{"id":"https://openalex.org/W2995640339","doi":"https://doi.org/10.1186/s12864-019-6360-3","title":"Network analysis uncovers putative genes affecting resistance to tick infestation in Braford cattle skin","display_name":"Network analysis uncovers putative genes affecting resistance to tick infestation in Braford cattle skin","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2995640339","doi":"https://doi.org/10.1186/s12864-019-6360-3","mag":"2995640339","pmid":"https://pubmed.ncbi.nlm.nih.gov/31856720","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6923859"},"language":"en","primary_location":{"id":"doi:10.1186/s12864-019-6360-3","doi":"https://doi.org/10.1186/s12864-019-6360-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-019-6360-3","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-019-6360-3","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-019-6360-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068461478","display_name":"Daniela D. Mor\u00e9","orcid":"https://orcid.org/0000-0002-3760-6757","observed_orcids":["https://orcid.org/0000-0002-3760-6757"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284042","display_name":"Embrapa Pecu\u00e1ria Sudeste","ror":"https://ror.org/02tcyjz11","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniela D. Mor\u00e9","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004727061","display_name":"F. F. Cardoso","orcid":"https://orcid.org/0000-0002-4145-1049","observed_orcids":["https://orcid.org/0000-0002-4145-1049"]},"institutions":[{"id":"https://openalex.org/I169248161","display_name":"Universidade Federal de Pelotas","ror":"https://ror.org/05msy9z54","country_code":"BR","type":"education","lineage":["https://openalex.org/I169248161"]},{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405285346","display_name":"Embrapa Pecu\u00e1ria Sul","ror":"https://ror.org/058j9ky09","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fernando F. Cardoso","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil","Federal University of Pelotas, Cap\u00e3o do Le\u00e3o, Rio Grande do Sul, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]},{"raw_affiliation_string":"Federal University of Pelotas, Cap\u00e3o do Le\u00e3o, Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I169248161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026174887","display_name":"Maur\u00edcio A. Mudadu","orcid":"https://orcid.org/0000-0002-2767-2507","observed_orcids":["https://orcid.org/0000-0002-2767-2507"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284356","display_name":"Embrapa Agricultura Digital","ror":"https://ror.org/03d8jng87","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284356"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maur\u00edcio A. Mudadu","raw_affiliation_strings":["EMBRAPA Inform\u00e1tica Agropecu\u00e1ria, Campinas, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Inform\u00e1tica Agropecu\u00e1ria, Campinas, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284356"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112424392","display_name":"Wilson Malag\u00f3","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284042","display_name":"Embrapa Pecu\u00e1ria Sudeste","ror":"https://ror.org/02tcyjz11","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Wilson Malag\u00f3-Jr","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069833859","display_name":"Claudia Cristina Gulias-Gomes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405285346","display_name":"Embrapa Pecu\u00e1ria Sul","ror":"https://ror.org/058j9ky09","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Claudia C. Gulias-Gomes","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038977341","display_name":"B. P. Sollero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405285346","display_name":"Embrapa Pecu\u00e1ria Sul","ror":"https://ror.org/058j9ky09","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bruna P. Sollero","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sul, Bag\u00e9, Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405285346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034157163","display_name":"A. M. G. Ibelli","orcid":"https://orcid.org/0000-0003-0626-8879","observed_orcids":["https://orcid.org/0000-0003-0626-8879"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405283075","display_name":"Embrapa Su\u00ednos e Aves","ror":"https://ror.org/00yxdqk51","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405283075"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Adriana M. G. Ibelli","raw_affiliation_strings":["EMBRAPA Su\u00ednos e Aves, Conc\u00f3rdia, Santa Catarina, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBRAPA Su\u00ednos e Aves, Conc\u00f3rdia, Santa Catarina, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405283075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080529521","display_name":"Luiz Lehmann Coutinho","orcid":"https://orcid.org/0000-0002-7266-8881","observed_orcids":["https://orcid.org/0000-0002-7266-8881"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiz L. Coutinho","raw_affiliation_strings":["Luiz de Queiroz College of Agriculture, University of S\u00e3o Paulo, Piracicaba, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Luiz de Queiroz College of Agriculture, University of S\u00e3o Paulo, Piracicaba, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044576559","display_name":"Luciana Correia de Almeida Regitano","orcid":"https://orcid.org/0000-0001-9242-8351","observed_orcids":["https://orcid.org/0000-0001-9242-8351"]},"institutions":[{"id":"https://openalex.org/I199691007","display_name":"Embrapa","ror":"https://ror.org/0482b5b22","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007"]},{"id":"https://openalex.org/I4405284042","display_name":"Embrapa Pecu\u00e1ria Sudeste","ror":"https://ror.org/02tcyjz11","country_code":"BR","type":"government","lineage":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Luciana C. A. Regitano","raw_affiliation_strings":["EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil. luciana.regitano@embrapa.br","EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9242-8351","affiliations":[{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil. luciana.regitano@embrapa.br","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]},{"raw_affiliation_string":"EMBRAPA Pecu\u00e1ria Sudeste, S\u00e3o Carlos, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5044576559"],"corresponding_institution_ids":["https://openalex.org/I199691007","https://openalex.org/I4405284042"],"apc_list":{"value":2145,"currency":"USD","value_usd":2145},"apc_paid":{"value":2145,"currency":"USD","value_usd":2145},"fwci":5.5657,"has_fulltext":true,"cited_by_count":45,"citation_normalized_percentile":{"value":0.97221847,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"20","issue":"1","first_page":"998","last_page":"998"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.02630000002682209,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tick-resistance","display_name":"tick resistance","score":0.9359999895095825},{"id":"https://openalex.org/keywords/braford-cattle","display_name":"Braford cattle","score":0.7900000214576721},{"id":"https://openalex.org/keywords/tick-infestation","display_name":"tick infestation","score":0.7329999804496765},{"id":"https://openalex.org/keywords/host-resistance-genetics","display_name":"host resistance genetics","score":0.328000009059906},{"id":"https://openalex.org/keywords/skin-transcriptome","display_name":"skin transcriptome","score":0.746999979019165},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9190000295639038},{"id":"https://openalex.org/keywords/wnt-signaling","display_name":"Wnt signaling","score":0.9309999942779541},{"id":"https://openalex.org/keywords/wnt7a","display_name":"Wnt7a","score":0.9980000257492065},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.7059999704360962},{"id":"https://openalex.org/keywords/nf-kb","display_name":"NF-kB","score":0.7860000133514404},{"id":"https://openalex.org/keywords/ap-1","display_name":"AP-1","score":0.8849999904632568},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.7900000214576721},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.6740000247955322},{"id":"https://openalex.org/keywords/il-22","display_name":"IL-22","score":0.996999979019165},{"id":"https://openalex.org/keywords/leukocyte-chemotaxis","display_name":"leukocyte chemotaxis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/skin-remodeling","display_name":"dermal remodeling","score":0.7429999709129333},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"genome-wide association study","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9282113313674927},{"id":"https://openalex.org/C2779780077","wikidata":"https://www.wikidata.org/wiki/Q4199106","display_name":"Tick infestation","level":3,"score":0.7927221655845642},{"id":"https://openalex.org/C2779620486","wikidata":"https://www.wikidata.org/wiki/Q10304508","display_name":"Tick","level":2,"score":0.7504218816757202},{"id":"https://openalex.org/C2776451879","wikidata":"https://www.wikidata.org/wiki/Q1292038","display_name":"Infestation","level":2,"score":0.6831293106079102},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6718964576721191},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6581417918205261},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.42162787914276123},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4208540916442871},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.1916634440422058},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.08669286966323853}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002418","descriptor_name":"Cattle Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002418","descriptor_name":"Cattle Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013984","descriptor_name":"Tick Infestations","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013984","descriptor_name":"Tick Infestations","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013984","descriptor_name":"Tick Infestations","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060449","descriptor_name":"Wnt Signaling Pathway","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060467","descriptor_name":"Disease Resistance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1186/s12864-019-6360-3","doi":"https://doi.org/10.1186/s12864-019-6360-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-019-6360-3","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-019-6360-3","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},{"id":"pmid:31856720","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31856720","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC genomics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6923859","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6923859/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"Text"},{"id":"pmh:oai:www.alice.cnptia.embrapa.br:doc/1118135","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/alice/handle/doc/1118135","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:americanae.aecid.es:2128271","doi":null,"is_oa":true,"landing_page_url":"http://www.alice.cnptia.embrapa.br/alice/handle/doc/1118135","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da EMBRAPA","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:38f0ea2a0b014cd1969070ab6335935c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/38f0ea2a0b014cd1969070ab6335935c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Genomics, Vol 20, Iss 1, Pp 1-20 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12864-019-6360-3","doi":"https://doi.org/10.1186/s12864-019-6360-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12864-019-6360-3","pdf_url":"https://bmcgenomics.biomedcentral.com/counter/pdf/10.1186/s12864-019-6360-3","source":{"id":"https://openalex.org/S28614077","display_name":"BMC Genomics","issn_l":"1471-2164","issn":["1471-2164"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Genomics","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3521043105","display_name":null,"funder_award_id":"02.09.07.004","funder_id":"https://openalex.org/F4320321675","funder_display_name":"Empresa Brasileira de Pesquisa Agropecu\u00e1ria"},{"id":"https://openalex.org/G3902415944","display_name":null,"funder_award_id":"02645/09-2","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G4015188921","display_name":null,"funder_award_id":"PNPD  02645/09\u20132","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G5623710353","display_name":null,"funder_award_id":"02.13.10.002","funder_id":"https://openalex.org/F4320321675","funder_display_name":"Empresa Brasileira de Pesquisa Agropecu\u00e1ria"},{"id":"https://openalex.org/G842983188","display_name":null,"funder_award_id":"PD 2012/24418-1","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320321675","display_name":"Empresa Brasileira de Pesquisa Agropecu\u00e1ria","ror":"https://ror.org/0482b5b22"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2995640339.pdf","grobid_xml":"https://content.openalex.org/works/W2995640339.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W176356951","https://openalex.org/W274546519","https://openalex.org/W1004089168","https://openalex.org/W1094579134","https://openalex.org/W1529404138","https://openalex.org/W1535820401","https://openalex.org/W1554414636","https://openalex.org/W1569678693","https://openalex.org/W1963859477","https://openalex.org/W1964631819","https://openalex.org/W1972209643","https://openalex.org/W1974554445","https://openalex.org/W1974595623","https://openalex.org/W1976182231","https://openalex.org/W1979103098","https://openalex.org/W1982036999","https://openalex.org/W1982336014","https://openalex.org/W1988952550","https://openalex.org/W1990103923","https://openalex.org/W1990352070","https://openalex.org/W1996722416","https://openalex.org/W2001064721","https://openalex.org/W2001624154","https://openalex.org/W2013275201","https://openalex.org/W2013888332","https://openalex.org/W2016387692","https://openalex.org/W2018938924","https://openalex.org/W2021686235","https://openalex.org/W2022570681","https://openalex.org/W2033497090","https://openalex.org/W2038131331","https://openalex.org/W2038539820","https://openalex.org/W2041935553","https://openalex.org/W2042750636","https://openalex.org/W2044665697","https://openalex.org/W2045671716","https://openalex.org/W2059675673","https://openalex.org/W2062841290","https://openalex.org/W2071192787","https://openalex.org/W2071588176","https://openalex.org/W2075774945","https://openalex.org/W2078128415","https://openalex.org/W2080378920","https://openalex.org/W2082159115","https://openalex.org/W2084686942","https://openalex.org/W2085297769","https://openalex.org/W2085680374","https://openalex.org/W2086969402","https://openalex.org/W2089509399","https://openalex.org/W2089590084","https://openalex.org/W2090811567","https://openalex.org/W2092571951","https://openalex.org/W2095056456","https://openalex.org/W2097147259","https://openalex.org/W2097849141","https://openalex.org/W2099357438","https://openalex.org/W2099438973","https://openalex.org/W2102025411","https://openalex.org/W2103390433","https://openalex.org/W2106464597","https://openalex.org/W2114104545","https://openalex.org/W2115379632","https://openalex.org/W2118090969","https://openalex.org/W2124638675","https://openalex.org/W2131888883","https://openalex.org/W2138028295","https://openalex.org/W2140729960","https://openalex.org/W2154344000","https://openalex.org/W2155350284","https://openalex.org/W2156626763","https://openalex.org/W2162041083","https://openalex.org/W2163350781","https://openalex.org/W2167034392","https://openalex.org/W2188896267","https://openalex.org/W2205614565","https://openalex.org/W2270785563","https://openalex.org/W2283933088","https://openalex.org/W2336176678","https://openalex.org/W2481660200","https://openalex.org/W2549263570","https://openalex.org/W2573146861","https://openalex.org/W2584003481","https://openalex.org/W2625585514","https://openalex.org/W2764102439","https://openalex.org/W2769496038","https://openalex.org/W2773128614","https://openalex.org/W2778951956","https://openalex.org/W2781636389","https://openalex.org/W2794796466","https://openalex.org/W2888364810","https://openalex.org/W2952454870","https://openalex.org/W4233623317","https://openalex.org/W4313371816"],"related_works":["https://openalex.org/W4392773800","https://openalex.org/W2738810096","https://openalex.org/W7159896638","https://openalex.org/W4283168102","https://openalex.org/W4319734041","https://openalex.org/W1567449216","https://openalex.org/W4392744857","https://openalex.org/W6982001351","https://openalex.org/W4263124","https://openalex.org/W4286489038"],"abstract_inverted_index":{"BACKGROUND:":[0],"Genetic":[1],"resistance":[2,38,171,191,320,335],"in":[3,164,169,184,200,211,321,336],"cattle":[4,315],"is":[5],"considered":[6],"a":[7,182,255,268],"suitable":[8],"way":[9],"to":[10,39,71,83,166,323,327],"control":[11],"tick":[12,40,67,108,167,324,334],"burden":[13],"and":[14,24,51,61,78,87,103,124,136,153,174,206,227,229,290,301],"its":[15],"consequent":[16],"losses":[17],"for":[18,284,299,333],"livestock":[19],"production.":[20],"Exploring":[21],"tick-resistant":[22],"(R)":[23],"tick-susceptible":[25],"(S)":[26],"hosts,":[27,56,138,202],"we":[28,157],"investigated":[29],"the":[30,34,59,65,140,147,185,193,220,230,251,261,264,279,294,328],"genetic":[31,85,310],"mechanisms":[32,311],"underlying":[33],"variation":[35,122],"of":[36,97,116,142,187,190,222,232,239,263,271,275,288,309,319,330],"Braford":[37,314],"infestation.":[41],"Skin":[42],"biopsies":[43],"from":[44,213],"four-times-artificially":[45],"infested":[46],"R":[47,135,214,300],"(n":[48,53],"=":[49,54],"20)":[50],"S":[52,137,285],"19)":[55],"obtained":[57],"before":[58,99],"first":[60],"24":[62],"h":[63],"after":[64,104],"fourth":[66],"infestation":[68,109,168],"were":[69,81,126,208,248,293],"submitted":[70],"RNA-Sequencing.":[72],"Differential":[73],"gene":[74,238],"expression,":[75],"functional":[76],"enrichment,":[77],"network":[79],"analysis":[80],"performed":[82],"identify":[84],"pathways":[86],"transcription":[88],"factors":[89],"(TFs)":[90],"affecting":[91],"host":[92],"resistance.":[93,272],"RESULTS:":[94],"Intergroup":[95],"comparisons":[96],"hosts":[98,247],"(Rpre":[100],"vs.":[101,106,151,155],"Spre)":[102],"(Rpost":[105],"Spost)":[107],"found":[110,158,210],"51":[111],"differentially":[112],"expressed":[113],"genes":[114,218,332],"(DEGs),":[115],"which":[117],"almost":[118],"all":[119],"presented":[120,312],"high":[121],"(TopDEGs),":[123],"38":[125],"redundant":[127],"genes.":[128],"Gene":[129],"expression":[130],"was":[131,198,243,278],"consistently":[132,244],"different":[133,188,317],"between":[134],"suggesting":[139],"existence":[141],"specific":[143],"anti-tick":[144,179],"mechanisms.":[145],"In":[146],"intragroup":[148],"comparisons,":[149],"Rpost":[150],"Rpre":[152],"Spost":[154],"Spre,":[156],"more":[159],"than":[160],"two":[161],"thousand":[162],"DEGs":[163],"response":[165,277,322],"both":[170,201],"groups.":[172],"Redundant":[173],"non-redundant":[175],"TopDEGs":[176,212],"with":[177,316],"potential":[178],"functions":[180],"suggested":[181],"role":[183],"development":[186],"levels":[189,318],"within":[192],"same":[194],"breed.":[195],"Leukocyte":[196],"chemotaxis":[197],"over-represented":[199],"whereas":[203],"skin":[204],"degradation":[205],"remodeling":[207],"only":[209],"hosts.":[215,286],"Also,":[216],"these":[217],"indicated":[219],"participation":[221],"cytokines,":[223],"such":[224],"as":[225,267],"IL6":[226],"IL22,":[228],"activation":[231],"Wingless":[233],"(WNT)-signaling":[234],"pathway.":[235],"A":[236],"central":[237],"this":[240],"pathway,":[241],"WNT7A,":[242],"modulated":[245],"when":[246],"compared.":[249],"Moreover,":[250],"findings":[252],"based":[253],"on":[254],"genome-wide":[256],"association":[257],"study":[258],"(GWAS)":[259],"corroborate":[260],"prediction":[262],"WNT-signaling":[265],"pathway":[266,282],"candidate":[269,331],"mechanism":[270],"The":[273],"regulation":[274],"immune":[276],"most":[280,295],"relevant":[281,296],"predicted":[283,298],"Members":[287],"Ap1":[289],"NF-kB":[291],"families":[292],"TFs":[297],"S,":[302],"respectively.":[303],"CONCLUSION:":[304],"This":[305],"work":[306],"provides":[307],"indications":[308],"by":[313],"infestation,":[325],"contributing":[326],"search":[329],"bovine.":[337]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2017,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-12-26T00:00:00"}