{"id":"https://openalex.org/W2995498901","doi":"https://doi.org/10.3390/ijms21010011","title":"The Interaction between 30b-5p miRNA and MBNL1 mRNA is Involved in Vascular Smooth Muscle Cell Differentiation in Patients with Coronary Atherosclerosis","display_name":"The Interaction between 30b-5p miRNA and MBNL1 mRNA is Involved in Vascular Smooth Muscle Cell Differentiation in Patients with Coronary Atherosclerosis","publication_year":2019,"publication_date":"2019-12-18","ids":{"openalex":"https://openalex.org/W2995498901","doi":"https://doi.org/10.3390/ijms21010011","mag":"2995498901","pmid":"https://pubmed.ncbi.nlm.nih.gov/31861407","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6982107"},"language":"en","primary_location":{"id":"doi:10.3390/ijms21010011","doi":"https://doi.org/10.3390/ijms21010011","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ijms21010011","pdf_url":"https://www.mdpi.com/1422-0067/21/1/11/pdf?version=1577022092","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/21/1/11/pdf?version=1577022092","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108574157","display_name":"Chin Cheng Woo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Chin Cheng Woo","raw_affiliation_strings":["Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100629212","display_name":"Wenting Liu","orcid":"https://orcid.org/0000-0003-1461-3740","observed_orcids":["https://orcid.org/0000-0003-1461-3740","https://orcid.org/0009-0008-3957-7671"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wenting Liu","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore 138672, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiao Yun Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I4210150261","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Xiao Yun Lin","raw_affiliation_strings":["Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054773456","display_name":"Rajkumar Dorajoo","orcid":"https://orcid.org/0000-0001-6608-2051","observed_orcids":["https://orcid.org/0000-0001-6608-2051"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Rajkumar Dorajoo","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore 138672, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-6608-2051","affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059806599","display_name":"Kee Wah Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Kee Wah Lee","raw_affiliation_strings":["Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031262573","display_name":"Mark Richards","orcid":"https://orcid.org/0000-0002-2023-8177","observed_orcids":["https://orcid.org/0000-0002-2023-8177"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ","SG"],"is_corresponding":false,"raw_author_name":"A Mark Richards","raw_affiliation_strings":["Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","Christchurch Heart Institute, University of Otago, Christchurch 8140, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Christchurch Heart Institute, University of Otago, Christchurch 8140, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036035574","display_name":"Chuen Neng Lee","orcid":"https://orcid.org/0000-0001-9748-4424","observed_orcids":["https://orcid.org/0000-0001-9748-4424"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I4210150261","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Chuen Neng Lee","raw_affiliation_strings":["Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore","Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"raw_affiliation_string":"Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022928039","display_name":"Thidathip Wongsurawat","orcid":"https://orcid.org/0000-0002-3659-2074","observed_orcids":["https://orcid.org/0000-0002-3659-2074"]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thidathip Wongsurawat","raw_affiliation_strings":["Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA"],"raw_orcid":"https://orcid.org/0000-0002-3659-2074","affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008739880","display_name":"Intawat Nookaew","orcid":"https://orcid.org/0000-0001-8901-1088","observed_orcids":["https://orcid.org/0000-0001-8901-1088"]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Intawat Nookaew","raw_affiliation_strings":["Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102771695","display_name":"V. A. Sorokin","orcid":"https://orcid.org/0000-0003-4106-3908","observed_orcids":["https://orcid.org/0000-0003-4106-3908"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I4210150261","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Vitaly Sorokin","raw_affiliation_strings":["Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore","Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac, Thoracic and Vascular Surgery, National University Hospital, National University Health System, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"raw_affiliation_string":"Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5102771695"],"corresponding_institution_ids":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1824},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1824},"fwci":3.3864,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.94770145,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"21","issue":"1","first_page":"11","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mbnl1","display_name":"MBNL1","score":0.9570000171661377},{"id":"https://openalex.org/keywords/mirna-mrna-interactions","display_name":"miRNA-mRNA interactions","score":0.8980000019073486},{"id":"https://openalex.org/keywords/vascular-smooth-muscle-cells","display_name":"vascular smooth muscle cells","score":0.9409999847412109},{"id":"https://openalex.org/keywords/vascular-smooth-muscle-cell-proliferation","display_name":"vascular smooth muscle cell proliferation","score":0.925000011920929},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.8999999761581421},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9319999814033508},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.8650000095367432},{"id":"https://openalex.org/keywords/aortic-wall","display_name":"aortic wall","score":0.8889999985694885},{"id":"https://openalex.org/keywords/mirna-target-prediction","display_name":"miRNA target prediction","score":0.5770000219345093}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.847453236579895},{"id":"https://openalex.org/C2779395532","wikidata":"https://www.wikidata.org/wiki/Q7916469","display_name":"Vascular smooth muscle","level":3,"score":0.8227294683456421},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.5789369344711304},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5733516216278076},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5295499563217163},{"id":"https://openalex.org/C125965507","wikidata":"https://www.wikidata.org/wiki/Q1516595","display_name":"Laser capture microdissection","level":4,"score":0.495246559381485},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4244844615459442},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3846895396709442},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3805433511734009},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33858293294906616},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3283824324607849},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32806235551834106},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.24933603405952454},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22014835476875305},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2139878273010254},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20710459351539612},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.13005292415618896}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009131","descriptor_name":"Muscle, Smooth, Vascular","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032389","descriptor_name":"Myocytes, Smooth Muscle","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/ijms21010011","doi":"https://doi.org/10.3390/ijms21010011","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ijms21010011","pdf_url":"https://www.mdpi.com/1422-0067/21/1/11/pdf?version=1577022092","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5954009","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6982107","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6982107","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6982107","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:31861407","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31861407","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/198977","doi":null,"is_oa":true,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/198977","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus OA2020","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3390/ijms21010011","doi":"https://doi.org/10.3390/ijms21010011","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/ijms21010011","pdf_url":"https://www.mdpi.com/1422-0067/21/1/11/pdf?version=1577022092","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310058","display_name":"University of Arkansas","ror":"https://ror.org/05jbt9m15"},{"id":"https://openalex.org/F4320310585","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71"},{"id":"https://openalex.org/F4320327250","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2995498901.pdf","grobid_xml":"https://content.openalex.org/works/W2995498901.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1530967851","https://openalex.org/W1617495083","https://openalex.org/W1964064254","https://openalex.org/W1985213868","https://openalex.org/W1987693883","https://openalex.org/W2003171726","https://openalex.org/W2017051002","https://openalex.org/W2033896075","https://openalex.org/W2037564399","https://openalex.org/W2039068212","https://openalex.org/W2051209145","https://openalex.org/W2068700406","https://openalex.org/W2080725268","https://openalex.org/W2089577900","https://openalex.org/W2099951294","https://openalex.org/W2103680698","https://openalex.org/W2108661174","https://openalex.org/W2109025917","https://openalex.org/W2129033842","https://openalex.org/W2133707124","https://openalex.org/W2134629862","https://openalex.org/W2135782858","https://openalex.org/W2144993485","https://openalex.org/W2150581509","https://openalex.org/W2159675211","https://openalex.org/W2167125089","https://openalex.org/W2169589032","https://openalex.org/W2171398108","https://openalex.org/W2274924551","https://openalex.org/W2290526113","https://openalex.org/W2291937808","https://openalex.org/W2296829780","https://openalex.org/W2316068191","https://openalex.org/W2343700030","https://openalex.org/W2490358729","https://openalex.org/W2592584523","https://openalex.org/W2742564882","https://openalex.org/W2790334200"],"related_works":["https://openalex.org/W4225094262","https://openalex.org/W2888096376","https://openalex.org/W2080677936","https://openalex.org/W3124342352","https://openalex.org/W2075026487","https://openalex.org/W2342117657","https://openalex.org/W3215697773","https://openalex.org/W2742564882","https://openalex.org/W7171869476","https://openalex.org/W2944290617"],"abstract_inverted_index":{"Vascular":[0],"smooth":[1],"muscle":[2],"cells":[3],"(VSMCs)":[4],"in":[5,163,188,199],"the":[6,15,27,41,120,141,151],"arterial":[7],"wall":[8,54],"have":[9],"diverse":[10],"functions.":[11],"In":[12,156],"pathological":[13],"states,":[14],"interplay":[16],"between":[17,119],"transcripts":[18],"and":[19,32,64,108,122,135,195],"microRNAs":[20],"(miRNAs)":[21],"leads":[22],"to":[23,80,96,131,158,184],"phenotypic":[24],"changes.":[25],"Understanding":[26],"regulatory":[28],"role":[29],"of":[30,43,103,181,186],"miRNAs":[31,115],"their":[33],"target":[34,153],"genes":[35],"may":[36],"reveal":[37],"how":[38],"VSMCs":[39],"modulate":[40],"pathogenesis":[42],"coronary":[44,58],"artery":[45,59],"disease.":[46],"Laser":[47],"capture":[48],"microdissection":[49],"was":[50,78,94],"performed":[51],"on":[52],"aortic":[53],"tissues":[55],"obtained":[56],"from":[57],"bypass":[60],"graft":[61],"patients":[62,105],"with":[63,88,165,174],"without":[65],"recent":[66],"acute":[67],"myocardial":[68],"infarction":[69],"(MI).":[70],"The":[71,83,100],"mSMRT-qPCR":[72],"miRNA":[73,84,101],"assay":[74],"platform":[75],"(MiRXES,":[76],"Singapore)":[77],"used":[79],"profile":[81],"miRNA.":[82],"data":[85,177],"were":[86,111,116],"co-analyzed":[87],"significant":[89],"mRNA":[90],"transcripts.":[91],"TargetScan":[92,137],"7.1":[93],"applied":[95],"evaluate":[97],"miRNA\u2013mRNA":[98],"interactions.":[99],"profiles":[102],"29":[104],"(16":[106],"MI":[107,121],"13":[109],"non-MI)":[110],"evaluated.":[112],"Thirteen":[113],"VSMC-related":[114,142],"differentially":[117],"expressed":[118],"non-MI":[123],"groups.":[124],"Analysis":[125],"revealed":[126,138],"seven":[127],"miRNA-targeted":[128],"mRNAs":[129],"related":[130],"muscular":[132],"tissue":[133],"differentiation":[134],"proliferation.":[136],"that":[139,149,170,179],"among":[140],"transcripts,":[143],"MBNL1":[144,187],"had":[145],"a":[146],"recognition":[147],"site":[148],"matched":[150],"hsa-miR-30b-5p":[152,171,182],"seed":[154],"sequence.":[155],"addition":[157],"predicted":[159],"analysis,":[160],"our":[161],"experiment":[162],"vitro":[164],"human":[166],"VSMC":[167,193,200],"culture":[168],"confirmed":[169],"negatively":[172],"correlated":[173],"MBNL1.":[175],"Our":[176],"showed":[178],"overexpression":[180],"led":[183],"downregulation":[185],"VSMCs.":[189],"This":[190],"process":[191],"influences":[192],"proliferation":[194],"might":[196],"be":[197],"involved":[198],"differentiation.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":29},{"year":2020,"cited_by_count":6}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2019-12-26T00:00:00"}