{"id":"https://openalex.org/W2994863552","doi":"https://doi.org/10.15537/smj.2019.12.24712","title":"The diagnostic power of circulating micro ribonucleic acid 34a in combination with cancer antigen 15-3 as a potential biomarker of breast cancer","display_name":"The diagnostic power of circulating micro ribonucleic acid 34a in combination with cancer antigen 15-3 as a potential biomarker of breast cancer","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2994863552","doi":"https://doi.org/10.15537/smj.2019.12.24712","mag":"2994863552","pmid":"https://pubmed.ncbi.nlm.nih.gov/31828273","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6969640"},"language":"en","primary_location":{"id":"doi:10.15537/smj.2019.12.24712","doi":"https://doi.org/10.15537/smj.2019.12.24712","is_oa":true,"landing_page_url":"https://doi.org/10.15537/smj.2019.12.24712","pdf_url":null,"source":{"id":"https://openalex.org/S73848604","display_name":"Saudi Medical Journal","issn_l":"0379-5284","issn":["0379-5284","1658-3175"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319313","host_organization_name":"Ministry of Defence and Aviation","host_organization_lineage":["https://openalex.org/P4310319313"],"host_organization_lineage_names":["Ministry of Defence and Aviation"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.15537/smj.2019.12.24712","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026831762","display_name":"Anmar R. Raheem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]},{"id":"https://openalex.org/I4210103044","display_name":"Ministry of Health","ror":"https://ror.org/01b1c8m98","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4210103044"]},{"id":"https://openalex.org/I4210127754","display_name":"Ministry of Health","ror":"https://ror.org/030atj633","country_code":"SA","type":"government","lineage":["https://openalex.org/I4210127754"]},{"id":"https://openalex.org/I56409017","display_name":"Nahrain University","ror":"https://ror.org/05v2p9075","country_code":"IQ","type":"education","lineage":["https://openalex.org/I56409017"]}],"countries":["IQ","SA"],"is_corresponding":false,"raw_author_name":"Anmar R. Raheem","raw_affiliation_strings":["Department of Medical Laboratories, Al-Imamain Al-Kadhimain Medical City, Ministry of Health, Baghdad, Iraq. E-mail. anmar_alshamary@yahoo.com","From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Laboratories, Al-Imamain Al-Kadhimain Medical City, Ministry of Health, Baghdad, Iraq. E-mail. anmar_alshamary@yahoo.com","institution_ids":["https://openalex.org/I4210103044"]},{"raw_affiliation_string":"From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","institution_ids":["https://openalex.org/I4210127754"]},{"raw_affiliation_string":"from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","institution_ids":["https://openalex.org/I56409017"]},{"raw_affiliation_string":"from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065516380","display_name":"Omar F. Abdul\u2010Rasheed","orcid":"https://orcid.org/0000-0003-3016-9176","observed_orcids":["https://orcid.org/0000-0003-3016-9176"]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]},{"id":"https://openalex.org/I4210103044","display_name":"Ministry of Health","ror":"https://ror.org/01b1c8m98","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4210103044"]},{"id":"https://openalex.org/I4210127754","display_name":"Ministry of Health","ror":"https://ror.org/030atj633","country_code":"SA","type":"government","lineage":["https://openalex.org/I4210127754"]},{"id":"https://openalex.org/I56409017","display_name":"Nahrain University","ror":"https://ror.org/05v2p9075","country_code":"IQ","type":"education","lineage":["https://openalex.org/I56409017"]}],"countries":["IQ","SA"],"is_corresponding":true,"raw_author_name":"Omar F. Abdul-Rasheed","raw_affiliation_strings":["From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health; from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University; and from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health; from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University; and from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706","https://openalex.org/I4210103044","https://openalex.org/I56409017"]},{"raw_affiliation_string":"From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","institution_ids":["https://openalex.org/I4210127754"]},{"raw_affiliation_string":"from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","institution_ids":["https://openalex.org/I56409017"]},{"raw_affiliation_string":"from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023902785","display_name":"Manwar A. Al-Naqqash","orcid":"https://orcid.org/0000-0002-5009-5146","observed_orcids":["https://orcid.org/0000-0002-5009-5146","https://orcid.org/0000-0002-7185-2898","https://orcid.org/0000-0001-9070-5415"]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]},{"id":"https://openalex.org/I4210103044","display_name":"Ministry of Health","ror":"https://ror.org/01b1c8m98","country_code":"IQ","type":"government","lineage":["https://openalex.org/I4210103044"]},{"id":"https://openalex.org/I4210127754","display_name":"Ministry of Health","ror":"https://ror.org/030atj633","country_code":"SA","type":"government","lineage":["https://openalex.org/I4210127754"]},{"id":"https://openalex.org/I56409017","display_name":"Nahrain University","ror":"https://ror.org/05v2p9075","country_code":"IQ","type":"education","lineage":["https://openalex.org/I56409017"]}],"countries":["IQ","SA"],"is_corresponding":false,"raw_author_name":"Manwar A. Al-Naqqash","raw_affiliation_strings":["From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health; from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University; and from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health; from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University; and from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706","https://openalex.org/I4210103044","https://openalex.org/I56409017"]},{"raw_affiliation_string":"From the Department of Medical Laboratories (Raheem), Al-Imamain Al-Kadhimain Medical City, Ministry of Health","institution_ids":["https://openalex.org/I4210127754"]},{"raw_affiliation_string":"from the Department of Chemistry and Biochemistry (Abdul-Rasheed), College of Medicine, Al-Nahrain University","institution_ids":["https://openalex.org/I56409017"]},{"raw_affiliation_string":"from the Department of Surgery (Al-Naqqash), College of Medicine, Baghdad University, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5065516380"],"corresponding_institution_ids":["https://openalex.org/I135120706","https://openalex.org/I4210103044","https://openalex.org/I4210127754","https://openalex.org/I56409017"],"apc_list":null,"apc_paid":null,"fwci":0.5992,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.55210485,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"40","issue":"12","first_page":"1218","last_page":"1226"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8669999837875366},{"id":"https://openalex.org/keywords/mir-34a","display_name":"miR-34a","score":0.9520000219345093},{"id":"https://openalex.org/keywords/ca-15-3","display_name":"CA15-3","score":0.8849999904632568},{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":0.9950000047683716},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.8309999704360962},{"id":"https://openalex.org/keywords/non-invasive-diagnosis","display_name":"non-invasive diagnosis","score":0.7940000295639038},{"id":"https://openalex.org/keywords/benign-breast-tumors","display_name":"benign breast tumors","score":0.8149999976158142},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.6190000176429749},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9454119205474854},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7631807327270508},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.6617264747619629},{"id":"https://openalex.org/C2992389814","wikidata":"https://www.wikidata.org/wiki/Q2459684","display_name":"Cancer antigen","level":3,"score":0.6514687538146973},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.610436201095581},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.538859486579895},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5100510716438293},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38800641894340515},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35259920358657837},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29810231924057007},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09644103050231934},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007493","descriptor_name":"Iraq","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018396","descriptor_name":"Mucin-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D055088","descriptor_name":"Early Detection of Cancer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.15537/smj.2019.12.24712","doi":"https://doi.org/10.15537/smj.2019.12.24712","is_oa":true,"landing_page_url":"https://doi.org/10.15537/smj.2019.12.24712","pdf_url":null,"source":{"id":"https://openalex.org/S73848604","display_name":"Saudi Medical Journal","issn_l":"0379-5284","issn":["0379-5284","1658-3175"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319313","host_organization_name":"Ministry of Defence and Aviation","host_organization_lineage":["https://openalex.org/P4310319313"],"host_organization_lineage_names":["Ministry of Defence and Aviation"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6969640","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6969640/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6969640/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Med J","raw_type":"Text"},{"id":"pmid:31828273","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31828273","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi medical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.15537/smj.2019.12.24712","doi":"https://doi.org/10.15537/smj.2019.12.24712","is_oa":true,"landing_page_url":"https://doi.org/10.15537/smj.2019.12.24712","pdf_url":null,"source":{"id":"https://openalex.org/S73848604","display_name":"Saudi Medical Journal","issn_l":"0379-5284","issn":["0379-5284","1658-3175"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319313","host_organization_name":"Ministry of Defence and Aviation","host_organization_lineage":["https://openalex.org/P4310319313"],"host_organization_lineage_names":["Ministry of Defence and Aviation"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2994863552.pdf","grobid_xml":"https://content.openalex.org/works/W2994863552.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W20799819","https://openalex.org/W1958462865","https://openalex.org/W1964770525","https://openalex.org/W1995003417","https://openalex.org/W2004759933","https://openalex.org/W2010419462","https://openalex.org/W2045604306","https://openalex.org/W2090464574","https://openalex.org/W2101979288","https://openalex.org/W2107277218","https://openalex.org/W2117352205","https://openalex.org/W2139528114","https://openalex.org/W2169583213","https://openalex.org/W2170481258","https://openalex.org/W2277250648","https://openalex.org/W2467019844","https://openalex.org/W2591278765","https://openalex.org/W2747144355","https://openalex.org/W2799297134","https://openalex.org/W2884407886","https://openalex.org/W2889615536","https://openalex.org/W2905162720","https://openalex.org/W2914541512","https://openalex.org/W4234660912"],"related_works":["https://openalex.org/W2799297134","https://openalex.org/W7165141725","https://openalex.org/W3174603910","https://openalex.org/W4311321786","https://openalex.org/W2591278765","https://openalex.org/W4220777361","https://openalex.org/W2077173951","https://openalex.org/W4246406305","https://openalex.org/W3125223002","https://openalex.org/W2900977247"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"investigate":[2],"the":[3,25,57,99,115,131,140,152,162,186,199,203,219],"circulating":[4],"levels":[5],"of":[6,14,27,32,59,104,118,124,133,142,154,164,176,205,222],"microRNA-34a":[7],"(miRNA-34a)":[8],"as":[9,159,212],"a":[10,171,213],"novel":[11],"non-invasive":[12,215],"biomarker":[13],"breast":[15,72,134,156],"cancer":[16,135,204],"(BC).":[17],"Methods:":[18],"The":[19,122],"case-control":[20],"study":[21],"was":[22],"conducted":[23],"at":[24],"Department":[26],"Chemistry":[28],"and":[29,74,81,88,111,144,179,183,207],"Biochemistry,":[30],"College":[31],"Medicine,":[33],"Al-Nahrain":[34],"University,":[35],"Baghdad,":[36],"Iraq,":[37],"from":[38,61],"December":[39],"2018":[40],"to":[41,52,113],"April":[42],"2019.":[43],"Real-time":[44],"quantitative":[45],"polymerase":[46],"chain":[47],"reaction":[48],"has":[49,126,147],"been":[50,127,148],"employed":[51,211],"analyze":[53],"miRNA-34a":[54,125,145,178,208],"expression":[55,123,146,194],"in":[56,130,139,151,161,198],"samples":[58],"serum":[60,201],"90":[62],"participants":[63],"(30":[64],"patients":[65,69],"with":[66,70,137,202],"BC":[67,190],"30":[68,75],"benign":[71,155],"tumors":[73],"control":[76],"subjects)":[77],"after":[78],"RNA":[79],"extraction":[80],"reverse":[82],"transcription.":[83],"Cancer":[84],"antigen":[85,90],"15-3":[86],"(CA15-3)":[87],"carcinoembryonic":[89],"(CEA)":[91],"were":[92],"measured":[93],"by":[94],"ELISA.":[95],"Additionally,":[96],"we":[97],"analyzed":[98],"receiver":[100],"operating":[101,167],"characteristic":[102],"curves":[103],"various":[105],"markers,":[106],"including":[107],"miRNA":[108],"-34a,":[109],"CA15-3,":[110],"CEA,":[112],"assess":[114],"diagnostic":[116],"power":[117,175],"each":[119],"marker.":[120],"Results:":[121],"significantly":[128,149,196],"lower":[129],"group":[132,141,153,163],"compared":[136,158],"that":[138,160],"control,":[143],"reduced":[150],"tumor":[157],"control.":[165],"Receiver":[166],"characteristics":[168],"analysis":[169],"showed":[170],"very":[172],"good":[173],"discriminative":[174],"combined":[177],"CA15-3":[180],"(specificity=77.7%;":[181],"sensitivity=83.3%":[182],"areas":[184],"under":[185],"curve":[187],"=0.842)":[188],"for":[189,218],"patients.":[191],"Conclusion:":[192],"MicroRNA-34a":[193],"is":[195],"decreased":[197],"patients'":[200],"breast,":[206],"can":[209],"be":[210],"potential":[214],"molecular":[216],"marker":[217],"early":[220],"diagnosis":[221],"BC.":[223]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2019-12-26T00:00:00"}