{"id":"https://openalex.org/W2994820409","doi":"https://doi.org/10.1186/s12882-019-1655-9","title":"A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study","display_name":"A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2994820409","doi":"https://doi.org/10.1186/s12882-019-1655-9","mag":"2994820409","pmid":"https://pubmed.ncbi.nlm.nih.gov/31830936","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6909506"},"language":"en","primary_location":{"id":"doi:10.1186/s12882-019-1655-9","doi":"https://doi.org/10.1186/s12882-019-1655-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12882-019-1655-9","pdf_url":"https://bmcnephrol.biomedcentral.com/track/pdf/10.1186/s12882-019-1655-9","source":{"id":"https://openalex.org/S172421378","display_name":"BMC Nephrology","issn_l":"1471-2369","issn":["1471-2369"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://bmcnephrol.biomedcentral.com/track/pdf/10.1186/s12882-019-1655-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008851016","display_name":"Atsushi Yaguchi","orcid":"https://orcid.org/0000-0002-9235-605X","observed_orcids":["https://orcid.org/0000-0002-9235-605X"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Atsushi Yaguchi","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan. atsushi_yaguchi@pharm.kissei.co.jp","Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":"https://orcid.org/0000-0002-9235-605X","affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan. atsushi_yaguchi@pharm.kissei.co.jp","institution_ids":["https://openalex.org/I4210119256"]},{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068515999","display_name":"Kenji Akahane","orcid":"https://orcid.org/0000-0003-0778-6782","observed_orcids":["https://orcid.org/0000-0003-0778-6782"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Akahane","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078692391","display_name":"Kumi Tsuchioka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kumi Tsuchioka","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087327139","display_name":"Saori Yonekubo","orcid":"https://orcid.org/0000-0003-0577-0058","observed_orcids":["https://orcid.org/0000-0003-0577-0058"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Saori Yonekubo","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061895792","display_name":"Shota Yamamoto","orcid":"https://orcid.org/0000-0002-3948-1601","observed_orcids":["https://orcid.org/0000-0002-3948-1601"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shota Yamamoto","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090355438","display_name":"Yasuaki Tamai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasuaki Tamai","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052335186","display_name":"Satoshi Tatemichi","orcid":"https://orcid.org/0000-0003-4572-4507","observed_orcids":["https://orcid.org/0000-0003-4572-4507"]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Satoshi Tatemichi","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052382093","display_name":"Hiroo Takeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119256","display_name":"Kissei Pharmaceutical (Japan)","ror":"https://ror.org/028gkfr23","country_code":"JP","type":"company","lineage":["https://openalex.org/I4210119256"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroo Takeda","raw_affiliation_strings":["Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacology Research Group, Pharmacology and Pharmacokinetics Research Laboratory, R&D, Kissei Pharmaceutical Co., Ltd., 4365-1 Kashiwabara, Hotaka, Azumino, Nagano, 399-8304, Japan","institution_ids":["https://openalex.org/I4210119256"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5008851016"],"corresponding_institution_ids":["https://openalex.org/I4210119256"],"apc_list":{"value":2170,"currency":"USD","value_usd":2170},"apc_paid":{"value":2170,"currency":"USD","value_usd":2170},"fwci":0.9631,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.76070541,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"20","issue":"1","first_page":"465","last_page":"465"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phosphate-binders","display_name":"phosphate binders","score":0.9850000143051147},{"id":"https://openalex.org/keywords/calcium-carbonate","display_name":"calcium carbonate","score":0.8370000123977661},{"id":"https://openalex.org/keywords/sucroferric-oxyhydroxide","display_name":"sucroferric oxyhydroxide","score":0.9850000143051147},{"id":"https://openalex.org/keywords/sevelamer-hydrochloride","display_name":"sevelamer hydrochloride","score":0.996999979019165},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.8009999990463257},{"id":"https://openalex.org/keywords/serum-phosphorus","display_name":"serum phosphorus","score":0.7400000095367432},{"id":"https://openalex.org/keywords/dialysis","display_name":"dialysis","score":0.6309999823570251},{"id":"https://openalex.org/keywords/gastrointestinal-ph","display_name":"gastrointestinal pH","score":0.8600000143051147}],"concepts":[{"id":"https://openalex.org/C2778624547","wikidata":"https://www.wikidata.org/wiki/Q421317","display_name":"Lanthanum carbonate","level":4,"score":0.8272601962089539},{"id":"https://openalex.org/C2777425297","wikidata":"https://www.wikidata.org/wiki/Q904153","display_name":"Sevelamer","level":4,"score":0.7353668808937073},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.7055308818817139},{"id":"https://openalex.org/C2778039128","wikidata":"https://www.wikidata.org/wiki/Q23767","display_name":"Calcium carbonate","level":2,"score":0.6333681344985962},{"id":"https://openalex.org/C2779148903","wikidata":"https://www.wikidata.org/wiki/Q661790","display_name":"Phosphate binder","level":4,"score":0.5728403925895691},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.545569896697998},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.512726902961731},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5030924677848816},{"id":"https://openalex.org/C2780659211","wikidata":"https://www.wikidata.org/wiki/Q181699","display_name":"Carbonate","level":2,"score":0.5002918243408203},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4817345440387726},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.385213166475296},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.34045201539993286},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3326255679130554},{"id":"https://openalex.org/C2776036575","wikidata":"https://www.wikidata.org/wiki/Q1641062","display_name":"Hyperphosphatemia","level":3,"score":0.25123661756515503},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2445906102657318},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12356850504875183},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002119","descriptor_name":"Calcium Carbonate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002119","descriptor_name":"Calcium Carbonate","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005290","descriptor_name":"Ferric Compounds","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005290","descriptor_name":"Ferric Compounds","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010710","descriptor_name":"Phosphates","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013395","descriptor_name":"Sucrose","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D013395","descriptor_name":"Sucrose","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12882-019-1655-9","doi":"https://doi.org/10.1186/s12882-019-1655-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12882-019-1655-9","pdf_url":"https://bmcnephrol.biomedcentral.com/track/pdf/10.1186/s12882-019-1655-9","source":{"id":"https://openalex.org/S172421378","display_name":"BMC Nephrology","issn_l":"1471-2369","issn":["1471-2369"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Nephrology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5872437","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6909506","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6909506","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6909506","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Nephrol","raw_type":"Text"},{"id":"pmid:31830936","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31830936","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC nephrology","raw_type":"Comparative Study"},{"id":"pmh:oai:doaj.org/article:1179c30c5268418592710baf450fb8ee","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1179c30c5268418592710baf450fb8ee","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Nephrology, Vol 20, Iss 1, Pp 1-12 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12882-019-1655-9","doi":"https://doi.org/10.1186/s12882-019-1655-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12882-019-1655-9","pdf_url":"https://bmcnephrol.biomedcentral.com/track/pdf/10.1186/s12882-019-1655-9","source":{"id":"https://openalex.org/S172421378","display_name":"BMC Nephrology","issn_l":"1471-2369","issn":["1471-2369"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Nephrology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316495","display_name":"Kissei","ror":"https://ror.org/028gkfr23"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2994820409.pdf","grobid_xml":"https://content.openalex.org/works/W2994820409.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1462714624","https://openalex.org/W1494926937","https://openalex.org/W1833121085","https://openalex.org/W1901381621","https://openalex.org/W1933163786","https://openalex.org/W1963541108","https://openalex.org/W1967791683","https://openalex.org/W1981461721","https://openalex.org/W1982049511","https://openalex.org/W1995714199","https://openalex.org/W2002822427","https://openalex.org/W2015402531","https://openalex.org/W2015786599","https://openalex.org/W2023653442","https://openalex.org/W2053932423","https://openalex.org/W2056035912","https://openalex.org/W2056614431","https://openalex.org/W2071516781","https://openalex.org/W2083738012","https://openalex.org/W2085757856","https://openalex.org/W2102420952","https://openalex.org/W2105719970","https://openalex.org/W2113262086","https://openalex.org/W2123780246","https://openalex.org/W2139932170","https://openalex.org/W2146507287","https://openalex.org/W2148869844","https://openalex.org/W2156899992","https://openalex.org/W2165096152","https://openalex.org/W2172159264","https://openalex.org/W2236453181","https://openalex.org/W2284523118","https://openalex.org/W2313433516","https://openalex.org/W2317296551","https://openalex.org/W2515429597","https://openalex.org/W2551770172","https://openalex.org/W2723066115","https://openalex.org/W2763043360","https://openalex.org/W2907854450"],"related_works":["https://openalex.org/W2236453181","https://openalex.org/W2723066115","https://openalex.org/W2907854450","https://openalex.org/W4403859660","https://openalex.org/W2330128250","https://openalex.org/W1993742910","https://openalex.org/W2000598460","https://openalex.org/W2117639138","https://openalex.org/W2056694775","https://openalex.org/W2751909540"],"abstract_inverted_index":{"BACKGROUND:":[0],"Approximately":[1],"30%":[2],"of":[3,21,29,33,40,50,130,162,174,214,237,249,260,277,289,307,321],"patients":[4],"on":[5],"dialysis":[6],"received":[7],"combination":[8,34,79,230],"therapy":[9],"for":[10,18,88,119],"their":[11],"phosphate":[12,22,74,83,116,131],"binder":[13],"prescription;":[14],"however,":[15],"few":[16],"studies":[17],"combined":[19,44,60,201,218,247,275],"effects":[20,202],"binders":[23,75,117],"are":[24],"reported.":[25],"For":[26,65,103],"the":[27,31,38,72,93,95,99,114,144,150,166,170,193,225,229,238,242,246,274,319,322,341],"purpose":[28],"evaluating":[30],"efficacy":[32,39,234,317,343],"therapy,":[35],"we":[36],"compared":[37],"sucroferric":[41],"oxyhydroxide":[42],"(PA21)":[43],"with":[45,48,61,183,219,335],"calcium":[46,62,69,111,184,220,252,265,282,294,310,336],"carbonate":[47,52,70,112,181,185,221,253,262,266,279,283,295,311,329,337],"that":[49,208,259,288,305,326],"lanthanum":[51,180,261,278,328],"hydrate,":[53],"sevelamer":[54,120,176],"hydrochloride,":[55,177],"and":[56,71,113,149,156,179,228,251,258,264,281,287,293,309,314,325,331],"ferric":[57,215,290,332],"citrate":[58,216,291,333],"hydrate":[59,182,217,263,280,292,330,334],"carbonate.":[63],"METHODS:":[64],"in":[66,78,82,98,104,124,167,207,243],"vitro":[67,168],"studies,":[68,106],"other":[73,115],"alone":[76,122],"or":[77,123,137,190],"were":[80,108,141,154,203,270,299],"stirred":[81],"solution":[84,132],"at":[85,146,254,267,284,296],"pH":[86,135,206,256,268,285,297,324],"2-8":[87],"2":[89,136,269,298],"h.":[90],"After":[91],"centrifuging":[92],"suspension,":[94],"phosphorus":[96,152],"level":[97],"supernatant":[100],"was":[101,186,222],"determined.":[102],"vivo":[105,244],"rats":[107,145],"orally":[109],"administered":[110],"(except":[118],"hydrochloride)":[121],"combination,":[125],"followed":[126],"by":[127],"oral":[128],"administration":[129],"adjusted":[133],"to":[134,189,205],"7.":[138],"Serum":[139],"samples":[140],"collected":[142],"from":[143],"predetermined":[147],"timepoints":[148],"serum":[151],"levels":[153],"determined":[155],"analyzed":[157],"using":[158],"a":[159],"two-way":[160],"analysis":[161],"variance.":[163],"RESULTS:":[164],"In":[165,241,272],"study,":[169,245],"measured":[171,211],"phosphate-binding":[172,212],"capacity":[173,213],"combining":[175,327],"PA21,":[178],"approximately":[187],"equal":[188],"greater":[191],"than":[192,224],"theoretical":[194,226],"values":[195,257],"under":[196,235,344],"most":[197],"conditions.":[198,240,346],"Furthermore,":[199],"these":[200],"insensitive":[204],"order.":[209],"The":[210],"smaller":[223],"values,":[227],"did":[231],"not":[232,339],"exhibit":[233],"any":[236],"tested":[239],"effect":[248,276],"PA21":[250,308],"both":[255],"additive.":[271],"contrast,":[273],"7":[286],"antagonistic.":[300],"CONCLUSIONS:":[301],"These":[302],"results":[303],"suggest":[304],"coadministration":[306],"showed":[312],"good":[313],"relatively":[315],"stable":[316],"throughout":[318],"range":[320],"gastrointestinal":[323],"may":[338],"produce":[340],"expected":[342],"certain":[345]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-26T00:00:00"}