{"id":"https://openalex.org/W2994746417","doi":"https://doi.org/10.1177/0022034519897910","title":"Heritability of Caries Scores, Trajectories, and Disease Subtypes","display_name":"Heritability of Caries Scores, Trajectories, and Disease Subtypes","publication_year":2020,"publication_date":"2020-01-06","ids":{"openalex":"https://openalex.org/W2994746417","doi":"https://doi.org/10.1177/0022034519897910","mag":"2994746417","pmid":"https://pubmed.ncbi.nlm.nih.gov/31905308","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7036480"},"language":"en","primary_location":{"id":"doi:10.1177/0022034519897910","doi":"https://doi.org/10.1177/0022034519897910","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0022034519897910","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0022034519897910","source":{"id":"https://openalex.org/S62865007","display_name":"Journal of Dental Research","issn_l":"0022-0345","issn":["0022-0345","1544-0591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dental Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/0022034519897910","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030245646","display_name":"Simon J. Haworth","orcid":"https://orcid.org/0000-0001-7793-7326","observed_orcids":["https://orcid.org/0000-0001-7793-7326"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"S. Haworth","raw_affiliation_strings":["Bristol Dental School, University of Bristol, Bristol, UK","Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK"],"raw_orcid":"https://orcid.org/0000-0001-7793-7326","affiliations":[{"raw_affiliation_string":"Bristol Dental School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482"]},{"raw_affiliation_string":"Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067278554","display_name":"Anders Esberg","orcid":"https://orcid.org/0000-0002-4430-8125","observed_orcids":["https://orcid.org/0000-0002-4430-8125"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"A. Esberg","raw_affiliation_strings":["Section of Cariology, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-4430-8125","affiliations":[{"raw_affiliation_string":"Section of Cariology, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070439713","display_name":"Pernilla Lif Holgerson","orcid":"https://orcid.org/0000-0002-2779-5865","observed_orcids":["https://orcid.org/0000-0002-2779-5865"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"P. Lif Holgerson","raw_affiliation_strings":["Section of Pedodontics, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pedodontics, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052670662","display_name":"Ralf Kuja\u2010Halkola","orcid":"https://orcid.org/0000-0002-3765-2067","observed_orcids":["https://orcid.org/0000-0002-3765-2067"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"R. Kuja-Halkola","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064383725","display_name":"Nicholas John Timpson","orcid":"https://orcid.org/0000-0002-7141-9189","observed_orcids":["https://orcid.org/0000-0002-7141-9189"]},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]},{"id":"https://openalex.org/I4387155195","display_name":"MRC Integrative Epidemiology Unit","ror":"https://ror.org/030qtrs05","country_code":"GB","type":"facility","lineage":["https://openalex.org/I36234482","https://openalex.org/I4210087105","https://openalex.org/I4387155195","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"N.J. Timpson","raw_affiliation_strings":["Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK","institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022810412","display_name":"Patrik K. E. Magnusson","orcid":"https://orcid.org/0000-0002-7315-7899","observed_orcids":["https://orcid.org/0000-0002-7315-7899"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"P.K.E. Magnusson","raw_affiliation_strings":["Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024645589","display_name":"Paul W. Franks","orcid":"https://orcid.org/0000-0002-0520-7604","observed_orcids":["https://orcid.org/0000-0002-0520-7604"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE","US"],"is_corresponding":false,"raw_author_name":"P.W. Franks","raw_affiliation_strings":["Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malm\u00f6, Sweden","Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054532454","display_name":"Ingegerd Johansson","orcid":"https://orcid.org/0000-0002-9227-8434","observed_orcids":["https://orcid.org/0000-0002-9227-8434"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"I. Johansson","raw_affiliation_strings":["Section of Cariology, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cariology, Department of Odontology, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5030245646"],"corresponding_institution_ids":["https://openalex.org/I36234482","https://openalex.org/I4387155195"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":6.3847,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.97253009,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"99","issue":"3","first_page":"264","last_page":"270"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.9125999808311462,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.9125999808311462,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.03229999914765358,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.01979999989271164,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.9980000257492065},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.9769999980926514},{"id":"https://openalex.org/keywords/genetic-factors","display_name":"genetic factors","score":0.5009999871253967},{"id":"https://openalex.org/keywords/fissure-caries","display_name":"fissure caries","score":0.828000009059906},{"id":"https://openalex.org/keywords/molars","display_name":"molars","score":0.7850000262260437},{"id":"https://openalex.org/keywords/shared-environmental-factors","display_name":"shared environmental factors","score":0.7730000019073486},{"id":"https://openalex.org/keywords/additive-genetic-effects","display_name":"additive genetic effects","score":0.796999990940094},{"id":"https://openalex.org/keywords/twin-studies","display_name":"twin studies","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C161890455","wikidata":"https://www.wikidata.org/wiki/Q1503548","display_name":"Heritability","level":2,"score":0.7397611141204834},{"id":"https://openalex.org/C169594400","wikidata":"https://www.wikidata.org/wiki/Q244775","display_name":"Twin study","level":3,"score":0.5253329277038574},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5031318068504333},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.4467867612838745},{"id":"https://openalex.org/C68873052","wikidata":"https://www.wikidata.org/wiki/Q349856","display_name":"Genetic variation","level":3,"score":0.44629156589508057},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44570836424827576},{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.44098877906799316},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3310384750366211},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.30418920516967773},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.11372816562652588},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09516477584838867},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.08286422491073608},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008963","descriptor_name":"Molar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014070","descriptor_name":"Tooth","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1177/0022034519897910","doi":"https://doi.org/10.1177/0022034519897910","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0022034519897910","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0022034519897910","source":{"id":"https://openalex.org/S62865007","display_name":"Journal of Dental Research","issn_l":"0022-0345","issn":["0022-0345","1544-0591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dental Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7036480","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7036480","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Dent Res","raw_type":"Text"},{"id":"pmid:31905308","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31905308","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of dental research","raw_type":"Journal Article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire/ef5f3816-8320-402f-a191-6763854a4c1d","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/ef5f3816-8320-402f-a191-6763854a4c1d","pdf_url":null,"source":{"id":"https://openalex.org/S7407055359","display_name":"Explore Bristol Research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haworth, S, Esberg, A, Lif Holgerson, P, Kuja-Halkola, R, Timpson, N J, Magnusson, P K E, Franks, P W & Johansson, I 2020, 'Heritability of Caries Scores, Trajectories and Disease Subtypes', Journal of Dental Research.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research-information.bris.ac.uk:openaire_cris_publications/ef5f3816-8320-402f-a191-6763854a4c1d","doi":null,"is_oa":true,"landing_page_url":"https://research-information.bris.ac.uk/en/publications/ef5f3816-8320-402f-a191-6763854a4c1d","pdf_url":null,"source":{"id":"https://openalex.org/S4306400895","display_name":"Bristol Research (University of Bristol)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36234482","host_organization_name":"University of Bristol","host_organization_lineage":["https://openalex.org/I36234482"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Haworth, S, Esberg, A, Lif Holgerson, P, Kuja-Halkola, R, Timpson, N J, Magnusson, P K E, Franks, P W & Johansson, I 2020, 'Heritability of Caries Scores, Trajectories and Disease Subtypes', Journal of Dental Research.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:DiVA.org:umu-167627","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167627","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:lup.lub.lu.se:d3a909f1-f149-478a-a4ba-01196be7332c","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/d3a909f1-f149-478a-a4ba-01196be7332c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0022-0345","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1177/0022034519897910","doi":"https://doi.org/10.1177/0022034519897910","is_oa":true,"landing_page_url":"https://doi.org/10.1177/0022034519897910","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/0022034519897910","source":{"id":"https://openalex.org/S62865007","display_name":"Journal of Dental Research","issn_l":"0022-0345","issn":["0022-0345","1544-0591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dental Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1393938142","display_name":"Understanding dental caries through genetics and mircobiota characterization - the GLIDE consortium","funder_award_id":"2015-02597","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G1429508699","display_name":"Gene discovery in periodontitis and dental caries - the GLIDE consortium","funder_award_id":"2011-03372","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G5440808206","display_name":null,"funder_award_id":"ACF-2019-25-014","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G5461123751","display_name":null,"funder_award_id":"2017-019","funder_id":"https://openalex.org/F4320322610","funder_display_name":"Stiftelsen Patentmedelsfonden f\u00f6r Odontologisk Profylaxforskning"},{"id":"https://openalex.org/G5832648839","display_name":"Swedish twin registry","funder_award_id":"2017-00641","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G7991887228","display_name":null,"funder_award_id":"2017-00641","funder_id":"https://openalex.org/F4320322315","funder_display_name":"Karolinska Institutet"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322610","display_name":"Stiftelsen Patentmedelsfonden f\u00f6r Odontologisk Profylaxforskning","ror":"https://ror.org/04941h613"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2994746417.pdf","grobid_xml":"https://content.openalex.org/works/W2994746417.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1931812874","https://openalex.org/W1964063358","https://openalex.org/W1969491734","https://openalex.org/W2009373307","https://openalex.org/W2013583398","https://openalex.org/W2025319758","https://openalex.org/W2028345563","https://openalex.org/W2031597554","https://openalex.org/W2042395000","https://openalex.org/W2049621853","https://openalex.org/W2057048062","https://openalex.org/W2058629897","https://openalex.org/W2064594026","https://openalex.org/W2073758800","https://openalex.org/W2094134686","https://openalex.org/W2095456034","https://openalex.org/W2107406434","https://openalex.org/W2109349396","https://openalex.org/W2139741257","https://openalex.org/W2144283392","https://openalex.org/W2169115160","https://openalex.org/W2527824850","https://openalex.org/W2536687083","https://openalex.org/W2597775634","https://openalex.org/W2728017684","https://openalex.org/W2756388071","https://openalex.org/W2941627994","https://openalex.org/W2945665018","https://openalex.org/W4244554398"],"related_works":["https://openalex.org/W2169115160","https://openalex.org/W2044482860","https://openalex.org/W2329440448","https://openalex.org/W2278986145","https://openalex.org/W6995845269","https://openalex.org/W2187983131","https://openalex.org/W7039031416","https://openalex.org/W2042395000","https://openalex.org/W4210704078","https://openalex.org/W2049621853"],"abstract_inverted_index":{"Previous":[0],"studies":[1],"report":[2],"that":[3,204,217],"dental":[4,74,80],"caries":[5,28,31,51,90,97,105,122,135,145,148,180,191,224,252,268],"is":[6,11],"partially":[7,201,227],"heritable,":[8],"but":[9,184],"there":[10],"uncertainty":[12],"in":[13,46,63,96,107,134,144,178,181,187,210,248,262,267,286],"the":[14,38,47,64,237,249,258,281,287],"magnitude":[15],"of":[16,22,41,49,89,109,118,132,142,155,170,176,190,213,223,231,245,251,260,264,273],"genetic":[17,24,42,125,194,246],"effects":[18],"and":[19,43,73,103,130,137,140,160,173,216,253,270,276],"little":[20,185],"understanding":[21],"how":[23],"factors":[25,45,126,164,195,247],"might":[26],"influence":[27],"progression":[29,98],"or":[30],"subtypes.":[32],"This":[33],"study":[34],"aimed":[35],"to":[36,60,70,220],"estimate":[37],"relative":[39],"importance":[40],"environmental":[44,163],"etiology":[48,250],"different":[50,205,211],"outcomes":[52],"using":[53],"a":[54],"twin-based":[55],"design.":[56],"Analysis":[57],"included":[58],"up":[59],"41,678":[61],"twins":[62],"Swedish":[65],"Twin":[66],"Register":[67],"aged":[68],"7":[69],"97":[71],"y,":[72],"data":[75,256],"were":[76,85,150,165,199],"obtained":[77],"from":[78,100,115],"preexisting":[79],"records.":[81],"The":[82,193],"outcome":[83],"measures":[84],"1)":[86,242],"summary":[87],"indices":[88],"experience,":[91],"2)":[92,254],"parameters":[93],"representing":[94],"trajectory":[95],"derived":[99,114],"longitudinal":[101,265],"modeling,":[102],"3)":[104],"scores":[106,136],"groups":[108,212,230],"biologically":[110],"similar":[111],"tooth":[112,119,214,232],"surfaces":[113,120,215,233],"hierarchical":[116],"clustering":[117],"(termed":[121],"clusters).":[123],"Additive":[124],"explained":[127,174],"between":[128,138,158],"49.1%":[129],"62.7%":[131],"variation":[133,143,177,186],"50.0%":[139],"60.5%":[141],"trajectories.":[146],"Seven":[147],"clusters":[149,172,189,198,235],"identified,":[151],"which":[152],"had":[153],"estimates":[154],"heritability":[156],"lying":[157],"41.9%":[159],"54.3%.":[161],"Shared":[162],"important":[166,209],"for":[167,283],"only":[168,200],"some":[169,221],"these":[171,197],"16%":[175],"fissure":[179],"molar":[182],"teeth":[183],"other":[188],"presentation.":[192],"influencing":[196],"overlapping,":[202],"suggesting":[203],"biological":[206],"processes":[207],"are":[208],"innate":[218],"liability":[219],"patterns":[222,272],"presentation":[225],"may":[226,278],"explain":[228],"why":[229],"form":[234],"within":[236],"mouth.":[238],"These":[239],"results":[240],"provide":[241],"improved":[243],"quantification":[244],"new":[255],"about":[257],"role":[259],"genetics":[261],"terms":[263],"changes":[266],"status":[269],"specific":[271],"disease":[274],"presentation,":[275],"they":[277],"help":[279],"lay":[280],"foundations":[282],"personalized":[284],"interventions":[285],"future.":[288]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-12-26T00:00:00"}