{"id":"https://openalex.org/W2993864019","doi":null,"title":"Taurine and dopamine-related effects of ethanol. An experimental study in rodents","display_name":"Taurine and dopamine-related effects of ethanol. An experimental study in rodents","publication_year":2019,"publication_date":"2019-11-18","ids":{"openalex":"https://openalex.org/W2993864019","mag":"2993864019"},"language":"en","primary_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/61682","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2077/61682","pdf_url":null,"source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012767089","display_name":"Lisa Ulenius","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Lisa Ulenius","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5012767089"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.5781000256538391,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.5781000256538391,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12533","display_name":"Aldose Reductase and Taurine","score":0.4074999988079071,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/taurine","display_name":"taurine","score":0.984000027179718},{"id":"https://openalex.org/keywords/ethanol","display_name":"ethanol","score":0.9150000214576721},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9359999895095825},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":0.996999979019165},{"id":"https://openalex.org/keywords/mesolimbic-dopamine-system","display_name":"mesolimbic dopamine system","score":0.8930000066757202},{"id":"https://openalex.org/keywords/alcohol-reinforcement","display_name":"alcohol reinforcement","score":0.9020000100135803},{"id":"https://openalex.org/keywords/alcoholism","display_name":"alcoholism","score":0.7960000038146973},{"id":"https://openalex.org/keywords/osmoregulation","display_name":"osmoregulation","score":0.8090000152587891},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.7910000085830688},{"id":"https://openalex.org/keywords/volume-regulated-anion-channel","display_name":"volume-regulated anion channel","score":0.9079999923706055},{"id":"https://openalex.org/keywords/locomotor-sensitization","display_name":"locomotor sensitization","score":0.7770000100135803},{"id":"https://openalex.org/keywords/energy-drinks","display_name":"energy drinks","score":0.8569999933242798},{"id":"https://openalex.org/keywords/chemogenetic-manipulation","display_name":"chemogenetic manipulation","score":0.6710000038146973}],"concepts":[{"id":"https://openalex.org/C2779701627","wikidata":"https://www.wikidata.org/wiki/Q207051","display_name":"Taurine","level":3,"score":0.746654748916626},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.7115585207939148},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.6009812951087952},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4375028908252716},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.36838483810424805},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.30763259530067444},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24257025122642517},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.09787604212760925}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:gupea.ub.gu.se:2077/61682","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2077/61682","pdf_url":null,"source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},{"id":"mag:2993864019","doi":null,"is_oa":false,"landing_page_url":"https://gupea.ub.gu.se/handle/2077/61682","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":340,"referenced_works":["https://openalex.org/W6854499","https://openalex.org/W8970091","https://openalex.org/W82912865","https://openalex.org/W118170242","https://openalex.org/W120625576","https://openalex.org/W182197855","https://openalex.org/W315706058","https://openalex.org/W325692610","https://openalex.org/W350375925","https://openalex.org/W577798607","https://openalex.org/W792325249","https://openalex.org/W1485678751","https://openalex.org/W1490848194","https://openalex.org/W1493864045","https://openalex.org/W1497508684","https://openalex.org/W1501723147","https://openalex.org/W1509881310","https://openalex.org/W1526855917","https://openalex.org/W1528675016","https://openalex.org/W1529567719","https://openalex.org/W1532230095","https://openalex.org/W1561878120","https://openalex.org/W1563267988","https://openalex.org/W1590067725","https://openalex.org/W1621301631","https://openalex.org/W1633847368","https://openalex.org/W1743649030","https://openalex.org/W1801570054","https://openalex.org/W1801785988","https://openalex.org/W1864800251","https://openalex.org/W1882675476","https://openalex.org/W1887149912","https://openalex.org/W1918535853","https://openalex.org/W1938300476","https://openalex.org/W1939041013","https://openalex.org/W1945462274","https://openalex.org/W1947243439","https://openalex.org/W1949404224","https://openalex.org/W1963889200","https://openalex.org/W1964287067","https://openalex.org/W1964381117","https://openalex.org/W1965352385","https://openalex.org/W1965528581","https://openalex.org/W1965880837","https://openalex.org/W1965949289","https://openalex.org/W1966403223","https://openalex.org/W1967619230","https://openalex.org/W1968160865","https://openalex.org/W1968900262","https://openalex.org/W1969082070","https://openalex.org/W1969992365","https://openalex.org/W1970168883","https://openalex.org/W1971556351","https://openalex.org/W1971837409","https://openalex.org/W1971993572","https://openalex.org/W1972265008","https://openalex.org/W1972413828","https://openalex.org/W1972559070","https://openalex.org/W1974265765","https://openalex.org/W1976482412","https://openalex.org/W1977844884","https://openalex.org/W1978866433","https://openalex.org/W1979768742","https://openalex.org/W1980277133","https://openalex.org/W1980478962","https://openalex.org/W1980695662","https://openalex.org/W1982422779","https://openalex.org/W1984390145","https://openalex.org/W1984631396","https://openalex.org/W1984963637","https://openalex.org/W1985327732","https://openalex.org/W1985779068","https://openalex.org/W1985904396","https://openalex.org/W1985908336","https://openalex.org/W1985931825","https://openalex.org/W1985982076","https://openalex.org/W1986269606","https://openalex.org/W1986794027","https://openalex.org/W1986918202","https://openalex.org/W1988659186","https://openalex.org/W1989248626","https://openalex.org/W1989594863","https://openalex.org/W1990189870","https://openalex.org/W1990336039","https://openalex.org/W1990546626","https://openalex.org/W1992559673","https://openalex.org/W1994093302","https://openalex.org/W1995451192","https://openalex.org/W1995494541","https://openalex.org/W1996519989","https://openalex.org/W1997238445","https://openalex.org/W1998335883","https://openalex.org/W1998585216","https://openalex.org/W1998620289","https://openalex.org/W2000060567","https://openalex.org/W2001865657","https://openalex.org/W2002577113","https://openalex.org/W2002660252","https://openalex.org/W2003123999","https://openalex.org/W2004650335","https://openalex.org/W2004763425","https://openalex.org/W2005534851","https://openalex.org/W2006090830","https://openalex.org/W2007188824","https://openalex.org/W2007469070","https://openalex.org/W2007525239","https://openalex.org/W2007736868","https://openalex.org/W2008088802","https://openalex.org/W2008969164","https://openalex.org/W2009562654","https://openalex.org/W2010775122","https://openalex.org/W2011246896","https://openalex.org/W2011830495","https://openalex.org/W2011885132","https://openalex.org/W2012553932","https://openalex.org/W2013274461","https://openalex.org/W2013488294","https://openalex.org/W2013734734","https://openalex.org/W2013792801","https://openalex.org/W2014415095","https://openalex.org/W2014459415","https://openalex.org/W2016414452","https://openalex.org/W2017897104","https://openalex.org/W2018785988","https://openalex.org/W2018808904","https://openalex.org/W2020091559","https://openalex.org/W2020860451","https://openalex.org/W2021172025","https://openalex.org/W2021677873","https://openalex.org/W2021923825","https://openalex.org/W2022027469","https://openalex.org/W2023335847","https://openalex.org/W2024479945","https://openalex.org/W2024493727","https://openalex.org/W2024540611","https://openalex.org/W2025440394","https://openalex.org/W2026137329","https://openalex.org/W2026255860","https://openalex.org/W2026627501","https://openalex.org/W2027889878","https://openalex.org/W2029626937","https://openalex.org/W2031799277","https://openalex.org/W2031887953","https://openalex.org/W2033374123","https://openalex.org/W2033376304","https://openalex.org/W2034586708","https://openalex.org/W2034788081","https://openalex.org/W2035264342","https://openalex.org/W2036042937","https://openalex.org/W2036169877","https://openalex.org/W2037457313","https://openalex.org/W2038425446","https://openalex.org/W2039993999","https://openalex.org/W2040047503","https://openalex.org/W2040397458","https://openalex.org/W2040740610","https://openalex.org/W2041712196","https://openalex.org/W2041991960","https://openalex.org/W2043311172","https://openalex.org/W2043403655","https://openalex.org/W2044816038","https://openalex.org/W2045341302","https://openalex.org/W2045556221","https://openalex.org/W2047165269","https://openalex.org/W2047313421","https://openalex.org/W2047942809","https://openalex.org/W2048336924","https://openalex.org/W2048723680","https://openalex.org/W2050317437","https://openalex.org/W2050654287","https://openalex.org/W2050760271","https://openalex.org/W2051473277","https://openalex.org/W2052225210","https://openalex.org/W2053101974","https://openalex.org/W2053169351","https://openalex.org/W2053368541","https://openalex.org/W2053661431","https://openalex.org/W2055872879","https://openalex.org/W2056015172","https://openalex.org/W2056124241","https://openalex.org/W2056671158","https://openalex.org/W2056878909","https://openalex.org/W2056883522","https://openalex.org/W2057281025","https://openalex.org/W2057344593","https://openalex.org/W2058305592","https://openalex.org/W2059378567","https://openalex.org/W2060588252","https://openalex.org/W2061342519","https://openalex.org/W2061549663","https://openalex.org/W2062214351","https://openalex.org/W2063604110","https://openalex.org/W2066733291","https://openalex.org/W2066779166","https://openalex.org/W2066848874","https://openalex.org/W2067060142","https://openalex.org/W2069072617","https://openalex.org/W2071029414","https://openalex.org/W2071042339","https://openalex.org/W2071761663","https://openalex.org/W2072371522","https://openalex.org/W2072830432","https://openalex.org/W2073537077","https://openalex.org/W2073636011","https://openalex.org/W2073830296","https://openalex.org/W2074991868","https://openalex.org/W2075038536","https://openalex.org/W2075455407","https://openalex.org/W2075605490","https://openalex.org/W2075821550","https://openalex.org/W2078837120","https://openalex.org/W2078995149","https://openalex.org/W2079590230","https://openalex.org/W2081631042","https://openalex.org/W2082532297","https://openalex.org/W2083067051","https://openalex.org/W2085653259","https://openalex.org/W2085719787","https://openalex.org/W2085743684","https://openalex.org/W2087086840","https://openalex.org/W2090931660","https://openalex.org/W2092241332","https://openalex.org/W2092271665","https://openalex.org/W2092512158","https://openalex.org/W2093046117","https://openalex.org/W2094146470","https://openalex.org/W2094896958","https://openalex.org/W2095088925","https://openalex.org/W2095191590","https://openalex.org/W2097744565","https://openalex.org/W2098620419","https://openalex.org/W2103624092","https://openalex.org/W2105173509","https://openalex.org/W2105393014","https://openalex.org/W2105557407","https://openalex.org/W2106862702","https://openalex.org/W2106923624","https://openalex.org/W2107157101","https://openalex.org/W2107277218","https://openalex.org/W2107402662","https://openalex.org/W2108914738","https://openalex.org/W2108973910","https://openalex.org/W2109064970","https://openalex.org/W2109366273","https://openalex.org/W2109518858","https://openalex.org/W2111986556","https://openalex.org/W2113070351","https://openalex.org/W2115362524","https://openalex.org/W2116867090","https://openalex.org/W2117516067","https://openalex.org/W2119453026","https://openalex.org/W2119569209","https://openalex.org/W2121135795","https://openalex.org/W2121379737","https://openalex.org/W2121584076","https://openalex.org/W2121680741","https://openalex.org/W2122592499","https://openalex.org/W2122946342","https://openalex.org/W2125588561","https://openalex.org/W2127946577","https://openalex.org/W2130092633","https://openalex.org/W2131491838","https://openalex.org/W2133180168","https://openalex.org/W2133191097","https://openalex.org/W2133615719","https://openalex.org/W2136192897","https://openalex.org/W2136717001","https://openalex.org/W2138067285","https://openalex.org/W2140893911","https://openalex.org/W2140948213","https://openalex.org/W2141536473","https://openalex.org/W2143850783","https://openalex.org/W2144312659","https://openalex.org/W2147381727","https://openalex.org/W2148496269","https://openalex.org/W2149232781","https://openalex.org/W2149361364","https://openalex.org/W2149927155","https://openalex.org/W2151607303","https://openalex.org/W2151895324","https://openalex.org/W2153368683","https://openalex.org/W2153379328","https://openalex.org/W2153532459","https://openalex.org/W2153773787","https://openalex.org/W2155090722","https://openalex.org/W2155612669","https://openalex.org/W2156257459","https://openalex.org/W2160585483","https://openalex.org/W2161971891","https://openalex.org/W2162097818","https://openalex.org/W2162445773","https://openalex.org/W2163602805","https://openalex.org/W2165398609","https://openalex.org/W2165531785","https://openalex.org/W2167411738","https://openalex.org/W2168550816","https://openalex.org/W2170081966","https://openalex.org/W2170528269","https://openalex.org/W2170672399","https://openalex.org/W2171098630","https://openalex.org/W2171928265","https://openalex.org/W2173087970","https://openalex.org/W2173939482","https://openalex.org/W2174764226","https://openalex.org/W2177909750","https://openalex.org/W2179007014","https://openalex.org/W2183513800","https://openalex.org/W2234997493","https://openalex.org/W2275148408","https://openalex.org/W2278090360","https://openalex.org/W2284615312","https://openalex.org/W2318335207","https://openalex.org/W2330761586","https://openalex.org/W2342980102","https://openalex.org/W2345391691","https://openalex.org/W2345832187","https://openalex.org/W2404371002","https://openalex.org/W2405778770","https://openalex.org/W2418214732","https://openalex.org/W2472534388","https://openalex.org/W2491859250","https://openalex.org/W2520320217","https://openalex.org/W2557290778","https://openalex.org/W2615827284","https://openalex.org/W2618452469","https://openalex.org/W2733140764","https://openalex.org/W2745223669","https://openalex.org/W2746023311","https://openalex.org/W2747664491","https://openalex.org/W2766132918","https://openalex.org/W2778311067","https://openalex.org/W2804376135","https://openalex.org/W2904542956","https://openalex.org/W2910981559","https://openalex.org/W2915270937","https://openalex.org/W2928114850","https://openalex.org/W2945728886","https://openalex.org/W4210950533","https://openalex.org/W4414004094","https://openalex.org/W6892271164"],"related_works":["https://openalex.org/W2990570015","https://openalex.org/W2746023311","https://openalex.org/W2945728886","https://openalex.org/W2747664491","https://openalex.org/W1945462274","https://openalex.org/W96294015","https://openalex.org/W7217679774","https://openalex.org/W2285748194","https://openalex.org/W2122125202","https://openalex.org/W2005534851"],"abstract_inverted_index":{"The":[0,87],"reinforcing":[1,212],"properties":[2,213,271],"of":[3,10,89,100,109,124,214,219,230,256,272,326],"alcohol":[4,41,44,347,353],"(ethanol)":[5],"are":[6,30],"associated":[7],"with":[8,138,151,201,233,277,355],"activation":[9],"the":[11,16,22,84,94,121,142,169,196,211,215,259,268,344],"mesolimbic":[12],"dopamine":[13,20,67,115,134,248,269,331],"system":[14,29],"and":[15,43,69,133,154,198,244,279,293,297,319],"concomitant":[17],"increase":[18,54,65,187,345],"in":[19,21,27,38,55,60,80,159,220,238,346,350],"nucleus":[23],"accumbens":[24],"(nAc).":[25],"Changes":[26],"this":[28,125,145],"thought":[31],"to":[32,64,82,98,128,192,195,210,240,251,343],"be":[33],"a":[34,52,106,171,206,234,246],"predominant":[35],"underlying":[36],"factor":[37],"promoting":[39],"excessive":[40],"intake":[42,88,108],"use":[45],"disorder.":[46],"We":[47],"have":[48],"previously":[49,208],"shown":[50],"that":[51,71,164,173,225,284,307],"simultaneous":[53],"endogenous":[56],"taurine":[57,90,110,132,167,179,199,236,263,286,310,338,340],"is":[58,78,117,174,288,333],"required":[59],"order":[61,81],"for":[62],"ethanol":[63,136,231,242,313],"nAc":[66,309],"levels,":[68],"hypothesize":[70],"taurine,":[72],"which":[73],"acts":[74],"as":[75],"an":[76,323],"osmoregulator,":[77],"released":[79],"re-equilibrate":[83],"osmotic":[85],"pressure.":[86],"has":[91],"escalated":[92],"over":[93],"last":[95],"decade":[96],"due":[97],"consumption":[99,348],"taurine-containing":[101],"energy":[102,356],"drinks,":[103],"but":[104],"whether":[105],"long-term":[107],"induces":[111],"adaptations":[112],"influencing":[113],"ethanol-induced":[114,204,285,330],"elevation":[116,237],"not":[118,175,186,266,289,334],"clear.":[119],"Thus,":[120],"overall":[122],"aim":[123],"thesis":[126],"was":[127],"investigate":[129],"correlations":[130],"between":[131],"during":[135],"exposure,":[137,339],"special":[139],"focus":[140],"on":[141],"nAc.":[143],"To":[144],"end,":[146],"behavioral":[147,193],"tests":[148],"were":[149],"combined":[150,200],"neurochemical":[152],"measurements":[153],"gene":[155],"expression":[156],"analysis":[157],"performed":[158],"rodents.":[160],"Our":[161],"data":[162],"show":[163,224],"systemically":[165],"administrated":[166],"enters":[168],"CNS,":[170],"process":[172],"influenced":[176,335],"by":[177,336],"sub-chronic":[178,337],"treatment.":[180],"Even":[181,328],"though":[182,329],"acute":[183,241],"exposure":[184,190,264,314],"does":[185,265],"locomotion,":[188,205],"repeated":[189,262],"leads":[191],"sensitization":[194],"drug,":[197],"caffeine":[202],"potentiates":[203],"phenomenon":[207],"linked":[209],"drug.":[216],"By":[217,274],"means":[218],"vivo":[221],"microdialysis":[222,276],"we":[223,282,305],"rats":[226,252],"consuming":[227,253],"high":[228],"levels":[229,311],"respond":[232],"blunted":[235],"response":[239],"treatment,":[243],"exhibit":[245],"lower":[247],"tone":[249],"compared":[250],"low":[254],"amounts":[255],"ethanol.":[257,273],"At":[258],"same":[260],"time,":[261],"influence":[267],"elevating":[270],"combining":[275],"pharmacological":[278],"chemogenetic":[280],"manipulations,":[281],"found":[283],"release":[287,332],"action":[290],"potential":[291],"dependent":[292],"may":[294],"involve":[295],"astrocytes":[296,318],"volume":[298],"regulated":[299],"anion":[300],"channels":[301],"(VRACs).":[302],"In":[303],"conclusion,":[304],"suggest":[306],"increased":[308],"following":[312],"mainly":[315],"derives":[316],"from":[317],"involves":[320],"VRACs,":[321],"supporting":[322],"osmoregulatory":[324],"role":[325],"taurine.":[327],"could":[341],"contribute":[342],"seen":[349],"humans":[351],"drinking":[352],"mixed":[354],"drinks.":[357]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-13T00:00:00"}
