{"id":"https://openalex.org/W2993763808","doi":null,"title":"Recombinant Membrane-Targeted CD59 Inhibits the Growth of Choroidal Neovascular Complex in Murine Model of Laser-Induced Choroidal Neovascularization (CNV)","display_name":"Recombinant Membrane-Targeted CD59 Inhibits the Growth of Choroidal Neovascular Complex in Murine Model of Laser-Induced Choroidal Neovascularization (CNV)","publication_year":2010,"publication_date":"2010-04-17","ids":{"openalex":"https://openalex.org/W2993763808","mag":"2993763808"},"language":"en","primary_location":{"id":"mag:2993763808","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2369074","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019807835","display_name":"J. Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Liu","raw_affiliation_strings":["Univ of Arkansas for Med Sciences, Little Rock, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ of Arkansas for Med Sciences, Little Rock, Arkansas","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012585127","display_name":"P. Jha","orcid":"https://orcid.org/0009-0009-7211-8677","observed_orcids":["https://orcid.org/0009-0009-7211-8677"]},"institutions":[{"id":"https://openalex.org/I2799656382","display_name":"University of Arkansas Medical Center","ror":"https://ror.org/005k4dn45","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799656382"]},{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Jha","raw_affiliation_strings":["Ophthalmology, Jones Eye Institute - UAMS, Little Rock, Arkansas"],"raw_orcid":"https://orcid.org/0009-0009-7211-8677","affiliations":[{"raw_affiliation_string":"Ophthalmology, Jones Eye Institute - UAMS, Little Rock, Arkansas","institution_ids":["https://openalex.org/I2799656382","https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041702000","display_name":"V. V. Lyzogubov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799656382","display_name":"University of Arkansas Medical Center","ror":"https://ror.org/005k4dn45","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799656382"]},{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. V. Lyzogubov","raw_affiliation_strings":["Ophthalmology, Jones Eye Institute - UAMS, Little Rock, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, Jones Eye Institute - UAMS, Little Rock, Arkansas","institution_ids":["https://openalex.org/I2799656382","https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065261686","display_name":"Puran S. Bora","orcid":"https://orcid.org/0000-0003-4781-1217","observed_orcids":["https://orcid.org/0000-0003-4781-1217"]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Puran S. Bora","raw_affiliation_strings":["Ophthalmology/Jones Eye Inst, Univ of Arkansas for Med Sci, Little Rock, Arkansas"],"raw_orcid":"https://orcid.org/0000-0003-4781-1217","affiliations":[{"raw_affiliation_string":"Ophthalmology/Jones Eye Inst, Univ of Arkansas for Med Sci, Little Rock, Arkansas","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108250563","display_name":"Nalini S. Bora","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nalini S. Bora","raw_affiliation_strings":["Univ of Arkansas for Med Sciences, Little Rock, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ of Arkansas for Med Sciences, Little Rock, Arkansas","institution_ids":["https://openalex.org/I79620101"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.49734373,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"51","issue":"13","first_page":"405","last_page":"405"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd59","display_name":"CD59","score":0.9589999914169312},{"id":"https://openalex.org/keywords/choroidal-neovascularization","display_name":"choroidal neovascularization","score":0.8799999952316284},{"id":"https://openalex.org/keywords/recombinant-protein","display_name":"recombinant protein","score":0.8009999990463257},{"id":"https://openalex.org/keywords/laser-induced-cnv","display_name":"laser-induced CNV","score":0.8579999804496765},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.6539999842643738},{"id":"https://openalex.org/keywords/choroid","display_name":"choroid","score":0.640999972820282},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C2781359195","wikidata":"https://www.wikidata.org/wiki/Q5105209","display_name":"Choroidal neovascularization","level":3,"score":0.9712274074554443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47308021783828735},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.45305389165878296},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.444486141204834},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3945893347263336},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27438709139823914},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.17358967661857605},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05671977996826172},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0436326265335083}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2993763808","doi":null,"is_oa":false,"landing_page_url":"https://iovs.arvojournals.org/article.aspx?articleid=2369074","pdf_url":null,"source":{"id":"https://openalex.org/S76304953","display_name":"Investigative Ophthalmology & Visual Science","issn_l":"0146-0404","issn":["0146-0404","1552-5783"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321950","host_organization_name":"Cadmus Press","host_organization_lineage":["https://openalex.org/P4310321950"],"host_organization_lineage_names":["Cadmus Press"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigative Ophthalmology & Visual Science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2084557754","https://openalex.org/W776940134","https://openalex.org/W2993290960","https://openalex.org/W937729655","https://openalex.org/W2599199975","https://openalex.org/W1533359588","https://openalex.org/W762339248","https://openalex.org/W948047113","https://openalex.org/W1160334223","https://openalex.org/W3211736878"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2019-12-13T00:00:00"}