{"id":"https://openalex.org/W2993515369","doi":null,"title":"Changing pattern of valve surgery.","display_name":"Changing pattern of valve surgery.","publication_year":1996,"publication_date":"1996-11-01","ids":{"openalex":"https://openalex.org/W2993515369","mag":"2993515369","pmid":"https://pubmed.ncbi.nlm.nih.gov/8901730"},"language":"en","primary_location":{"id":"pmid:8901730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8901730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"V Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801845744","display_name":"Toronto General Hospital","ror":"https://ror.org/026pg9j08","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1325899441","https://openalex.org/I2801845744"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"V Rao","raw_affiliation_strings":["Division of Cardiovascular Surgery, Toronto Hospital, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Surgery, Toronto Hospital, Ontario, Canada","institution_ids":["https://openalex.org/I2801845744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089802232","display_name":"George T. Christakis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G T Christakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113586792","display_name":"Richard D. Weisel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R D Weisel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073670086","display_name":"Karen J. Buth","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K J Buth","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061655266","display_name":"John S. Ikonomidis","orcid":"https://orcid.org/0000-0002-1540-7167","observed_orcids":["https://orcid.org/0000-0002-1540-7167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J S Ikonomidis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102843738","display_name":"Toshizumi Shirai","orcid":"https://orcid.org/0000-0002-7465-6016","observed_orcids":["https://orcid.org/0000-0002-7465-6016"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Shirai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"G Cohen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Cohen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109070640","display_name":"T. David","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T E David","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8773,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.78939852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"94","issue":"9 Suppl","first_page":"II113","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aortic-valve-replacement","display_name":"aortic valve replacement","score":0.9860000014305115},{"id":"https://openalex.org/keywords/mitral-valve-replacement","display_name":"mitral valve replacement","score":1.0},{"id":"https://openalex.org/keywords/postoperative-mortality","display_name":"postoperative mortality","score":0.984000027179718},{"id":"https://openalex.org/keywords/perioperative-risk-factors","display_name":"perioperative risk factors","score":0.7480000257492065},{"id":"https://openalex.org/keywords/high-risk-patients","display_name":"high-risk patients","score":0.6389999985694885},{"id":"https://openalex.org/keywords/valvular-calcification","display_name":"valve calcification","score":0.6769999861717224},{"id":"https://openalex.org/keywords/cardiac-surgery-outcomes","display_name":"cardiac surgery outcomes","score":0.40799999237060547}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9671199321746826},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.7640693187713623},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5913633108139038},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.5883716344833374},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5334498882293701},{"id":"https://openalex.org/C2775854548","wikidata":"https://www.wikidata.org/wiki/Q6882369","display_name":"Mitral valve replacement","level":3,"score":0.46300366520881653},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4179738163948059},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.41670531034469604},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.4027324914932251},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.348043292760849},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3179250955581665},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.0987648069858551},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001021","descriptor_name":"Aortic Valve","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008943","descriptor_name":"Mitral Valve","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8901730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8901730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},{"id":"mag:2993515369","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8901730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2413588786","https://openalex.org/W2025114389","https://openalex.org/W2417628428","https://openalex.org/W2417565082","https://openalex.org/W2023449891","https://openalex.org/W2075499413","https://openalex.org/W2384519962","https://openalex.org/W1967891830","https://openalex.org/W2318624766","https://openalex.org/W2317600306"],"abstract_inverted_index":{"BACKGROUND:":[0],"Advances":[1],"in":[2,182,197,251,280,288],"surgical":[3],"technique":[4],"and":[5,15,47,57,91,105,112,120,165,245],"perioperative":[6,55],"myocardial":[7],"protection":[8],"have":[9,24,41],"reduced":[10,25],"the":[11,26,64,79,149,168,175,183,200,228,231,265],"risk":[12,53,160,173,241],"of":[13,21,28,66,115,132,171,177,213],"aortic":[14,71,294],"mitral":[16,74,296],"valve":[17,22,32,38,76,297],"surgery.":[18,298],"Improved":[19],"methods":[20],"repair":[23],"proportion":[27,170],"patients":[29,35,68,84,134,155,215,237],"who":[30,36,69,85,98],"require":[31,37],"replacement.":[33],"However,":[34],"replacement":[39,77],"often":[40],"advanced":[42],"disease":[43],"and/or":[44],"extensive":[45],"calcification":[46],"may":[48],"therefore":[49],"be":[50],"at":[51,78],"increased":[52],"for":[54,126,162,243],"morbidity":[56,291],"mortality.":[58],"METHODS":[59],"AND":[60],"RESULTS:":[61],"We":[62,82],"reviewed":[63],"results":[65],"2898":[67],"underwent":[70,86,135,216],"(AVR)":[72],"or":[73,262,290,295],"(MVR)":[75],"Toronto":[80],"Hospital.":[81],"compared":[83],"surgery":[87],"between":[88,102,199,264],"January":[89,103],"1982":[90],"December":[92,106],"1986":[93],"(early":[94],"group)":[95],"with":[96,156,227,238,293],"those":[97],"were":[99,124],"operated":[100],"on":[101],"1989":[104],"1993":[107],"(late":[108],"group).":[109],"The":[110],"univariable":[111],"multivariable":[113,240],"predictors":[114],"postoperative":[116,178,252],"low-output":[117],"syndrome":[118],"(LOS)":[119],"operative":[121,159],"mortality":[122,289],"(OM)":[123],"determined":[125],"each":[127],"time":[128],"period.":[129],"A":[130,211],"total":[131],"1779":[133],"AVR":[136],"(late,":[137,203,218,254,268],"n":[138,142,219,223],"=":[139,143,191,209,220,224,260,274],"997;":[140],"early,":[141,188,206,222,257,271],"782).":[144],"Multivariable":[145],"analyses":[146],"revealed":[147],"that":[148],"late":[150,184,232],"group":[151,185,233],"had":[152,234],"significantly":[153,235],"more":[154,236],"independent":[157],"pre-epidemiology":[158],"factors":[161,242],"both":[163],"OM":[164,198,244,263],"LOS.":[166,246],"Despite":[167,277],"greater":[169],"high":[172],"patients,":[174,282],"incidence":[176],"LOS":[179,253],"was":[180,194,248,284],"lower":[181],"(10%":[186],"versus":[187,205,256,270],"14%;":[189],"P":[190,208,259,273],".012).":[192],"There":[193,247],"no":[195,249,285],"difference":[196,250],"two":[201,266],"groups":[202,267],"3.4%":[204],"3.7%;":[207],".732).":[210],"Total":[212],"1119":[214],"MVR":[217],"493;":[221],"626).":[225],"Compared":[226],"early":[229],"group,":[230],"preoperative":[239],"19%":[255],"21%;":[258],".361)":[261],"5.8%":[269],"6.9%;":[272],".432).":[275],"CONCLUSIONS:":[276],"an":[278],"increase":[279,287],"high-risk":[281],"there":[283],"significant":[286],"associated":[292]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-12-13T00:00:00"}