{"id":"https://openalex.org/W2993351297","doi":"https://doi.org/10.1123/jpah.2018-0588","title":"High-Intensity Interval Versus Moderate-Intensity Continuous Training in Individuals With Parkinson\u2019s Disease: Hemodynamic and Functional Adaptation","display_name":"High-Intensity Interval Versus Moderate-Intensity Continuous Training in Individuals With Parkinson\u2019s Disease: Hemodynamic and Functional Adaptation","publication_year":2019,"publication_date":"2019-12-05","ids":{"openalex":"https://openalex.org/W2993351297","doi":"https://doi.org/10.1123/jpah.2018-0588","mag":"2993351297","pmid":"https://pubmed.ncbi.nlm.nih.gov/31810064"},"language":"en","primary_location":{"id":"doi:10.1123/jpah.2018-0588","doi":"https://doi.org/10.1123/jpah.2018-0588","is_oa":false,"landing_page_url":"https://doi.org/10.1123/jpah.2018-0588","pdf_url":null,"source":{"id":"https://openalex.org/S2755080209","display_name":"Journal of Physical Activity and Health","issn_l":"1543-3080","issn":["1543-3080","1543-5474"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310322142","host_organization_name":"Human Kinetics","host_organization_lineage":["https://openalex.org/P4310322142"],"host_organization_lineage_names":["Human Kinetics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Physical Activity and Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11449/196985","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024083301","display_name":"Bianca Fernandes","orcid":"https://orcid.org/0000-0002-9322-0066","observed_orcids":["https://orcid.org/0000-0002-9322-0066"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bianca Fernandes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065962741","display_name":"F\u00e1bio Augusto Barbieri","orcid":"https://orcid.org/0000-0002-3678-8456","observed_orcids":["https://orcid.org/0000-0002-3678-8456"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fabio Augusto Barbieri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006114289","display_name":"Fernanda Zane Arthuso","orcid":"https://orcid.org/0000-0003-1262-9036","observed_orcids":["https://orcid.org/0000-0003-1262-9036"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernanda Zane Arthuso","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043796343","display_name":"Fabiana Ara\u00fajo Silva","orcid":"https://orcid.org/0000-0002-2204-8123","observed_orcids":["https://orcid.org/0000-0002-2204-8123"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fabiana Ara\u00fajo Silva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091375080","display_name":"Gabriel Felipe Moretto","orcid":"https://orcid.org/0000-0002-3362-0981","observed_orcids":["https://orcid.org/0000-0002-3362-0981"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriel Felipe Moretto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032125059","display_name":"Luis Felipe Itikawa Imaizumi","orcid":"https://orcid.org/0000-0002-7884-2297","observed_orcids":["https://orcid.org/0000-0002-7884-2297"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luis Felipe Itikawa Imaizumi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083537763","display_name":"Awassi Yuphiwa Ngomane","orcid":"https://orcid.org/0000-0002-4301-5304","observed_orcids":["https://orcid.org/0000-0002-4301-5304"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Awassi Yophiwa Ngomane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019188918","display_name":"Guilherme Veiga Guimar\u00e3es","orcid":"https://orcid.org/0000-0003-2304-3110","observed_orcids":["https://orcid.org/0000-0003-2304-3110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guilherme Veiga Guimar\u00e3es","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5048005248","display_name":"Emmanuel Gomes Ciolac","orcid":"https://orcid.org/0000-0002-2397-8162","observed_orcids":["https://orcid.org/0000-0002-2397-8162"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emmanuel Gomes Ciolac","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.0905,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.91478392,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"17","issue":"1","first_page":"85","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.013000000268220901,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9860000014305115},{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":1.0},{"id":"https://openalex.org/keywords/moderate-intensity-continuous-training","display_name":"moderate-intensity continuous training","score":0.9509999752044678},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.6069999933242798},{"id":"https://openalex.org/keywords/hemodynamic-adaptation","display_name":"hemodynamic adaptation","score":0.8040000200271606},{"id":"https://openalex.org/keywords/endothelial-reactivity","display_name":"endothelial reactivity","score":0.9449999928474426},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":0.8330000042915344},{"id":"https://openalex.org/keywords/pulse-wave-velocity","display_name":"pulse wave velocity","score":0.875},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.7149999737739563},{"id":"https://openalex.org/keywords/resting-heart-rate","display_name":"resting heart rate","score":0.9390000104904175},{"id":"https://openalex.org/keywords/cardiorespiratory-fitness","display_name":"cardiorespiratory fitness","score":0.9160000085830688},{"id":"https://openalex.org/keywords/functional-capacity","display_name":"functional capacity","score":0.6200000047683716},{"id":"https://openalex.org/keywords/sit-to-stand","display_name":"sit-to-stand","score":0.7829999923706055},{"id":"https://openalex.org/keywords/timed-up-and-go-test","display_name":"Timed Up and Go test","score":0.875},{"id":"https://openalex.org/keywords/6-minute-walk-test","display_name":"6-minute walk test","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C2781444488","wikidata":"https://www.wikidata.org/wiki/Q2756206","display_name":"High-intensity interval training","level":2,"score":0.7507515549659729},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.7265819311141968},{"id":"https://openalex.org/C2777973682","wikidata":"https://www.wikidata.org/wiki/Q1558681","display_name":"Interval training","level":2,"score":0.7088811993598938},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.629539966583252},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6206072568893433},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5758957266807556},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5284587740898132},{"id":"https://openalex.org/C93038891","wikidata":"https://www.wikidata.org/wiki/Q1061524","display_name":"Intensity (physics)","level":2,"score":0.49355828762054443},{"id":"https://openalex.org/C2815619","wikidata":"https://www.wikidata.org/wiki/Q5165527","display_name":"Continuous training","level":2,"score":0.44874000549316406},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.4282742738723755},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3476867973804474},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3212772011756897},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072696","descriptor_name":"High-Intensity Interval Training","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1123/jpah.2018-0588","doi":"https://doi.org/10.1123/jpah.2018-0588","is_oa":false,"landing_page_url":"https://doi.org/10.1123/jpah.2018-0588","pdf_url":null,"source":{"id":"https://openalex.org/S2755080209","display_name":"Journal of Physical Activity and Health","issn_l":"1543-3080","issn":["1543-3080","1543-5474"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310322142","host_organization_name":"Human Kinetics","host_organization_lineage":["https://openalex.org/P4310322142"],"host_organization_lineage_names":["Human Kinetics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Physical Activity and Health","raw_type":"journal-article"},{"id":"pmid:31810064","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31810064","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of physical activity & health","raw_type":"Journal Article"},{"id":"pmh:oai:repositorio.unesp.br:11449/196985","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/196985","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:repositorio.unesp.br:11449/201454","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/201454","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"pmh:oai:repositorio.unesp.br:11449/196985","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11449/196985","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNESP","raw_type":"info:eu-repo/semantics/publishedVersion"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1971474283","https://openalex.org/W1973309526","https://openalex.org/W1980500725","https://openalex.org/W1986900472","https://openalex.org/W1987580873","https://openalex.org/W1987663503","https://openalex.org/W1988315365","https://openalex.org/W1994425852","https://openalex.org/W1997757260","https://openalex.org/W2008560062","https://openalex.org/W2009153050","https://openalex.org/W2018075046","https://openalex.org/W2027359268","https://openalex.org/W2031626165","https://openalex.org/W2038968238","https://openalex.org/W2073196815","https://openalex.org/W2084254617","https://openalex.org/W2107699610","https://openalex.org/W2126008330","https://openalex.org/W2135332831","https://openalex.org/W2137206121","https://openalex.org/W2154642316","https://openalex.org/W2165687339","https://openalex.org/W2166960383","https://openalex.org/W2287494067","https://openalex.org/W2416239662","https://openalex.org/W2424754939","https://openalex.org/W2512924993","https://openalex.org/W2586065799","https://openalex.org/W2606705525","https://openalex.org/W2611567019","https://openalex.org/W2747361224","https://openalex.org/W2762186704","https://openalex.org/W2780538322","https://openalex.org/W2891849919","https://openalex.org/W4211123396","https://openalex.org/W6647207265"],"related_works":["https://openalex.org/W2807260795","https://openalex.org/W7065323640","https://openalex.org/W4400646209","https://openalex.org/W3185846145","https://openalex.org/W3093704775","https://openalex.org/W4402663767","https://openalex.org/W7133881906","https://openalex.org/W4313649777","https://openalex.org/W4378221055","https://openalex.org/W7047626924"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"investigate":[2],"the":[3],"effect":[4],"of":[5,116],"high-intensity":[6],"interval":[7],"training":[8,14],"(HIIT)":[9],"versus":[10,121],"moderate-intensity":[11],"continuous":[12],"exercise":[13,183],"(MICE)":[15],"on":[16,189],"hemodynamic":[17,87],"and":[18,53,63,67,74,76,82,88,156,192],"functional":[19,68,89],"variables":[20,69,90],"in":[21,109,119,173,195],"individuals":[22,196],"with":[23,197],"Parkinson's":[24,198],"disease.":[25,199],"METHODS:":[26],"Twenty":[27],"participants":[28],"(13":[29],"men)":[30],"were":[31,91,167],"randomly":[32],"assigned":[33],"to":[34,100,144],"a":[35],"thrice-weekly":[36],"HIIT":[37,120,130,149,170],"(n":[38,43],"=":[39,44],"12)":[40],"or":[41,171],"MICE":[42,122,157,172],"8)":[45],"for":[46],"12":[47],"weeks.":[48],"Hemodynamic":[49],"(resting":[50],"heart":[51,64],"rate":[52,65],"blood":[54],"pressure,":[55],"carotid":[56],"femoral":[57],"pulse":[58],"wave":[59],"velocity,":[60],"endothelial":[61,190],"reactivity,":[62],"variability)":[66],"(5-time":[70],"sit-to-stand,":[71],"timed":[72],"up":[73],"go,":[75],"6-min":[77],"walking":[78,126],"tests)":[79],"assessed":[80],"before":[81],"after":[83,102,106,129,141,148,169],"training.":[84],"RESULTS:":[85],"Demographic,":[86],"similar":[92],"between":[93],"groups":[94],"at":[95],"baseline.":[96],"Endothelial":[97],"reactivity":[98,191],"tended":[99],"increase":[101],"HIIT,":[103],"but":[104,137],"not":[105,139],"MICE,":[107],"resulting":[108],"improved":[110,128,146],"level":[111],"(\u223c8%,":[112],"P":[113,134,153,161],"<":[114,135,154,162],".01)":[115],"this":[117],"variable":[118,176],"during":[123],"follow-up.":[124],"Six-minute":[125],"test":[127],"(10.4":[131],"\u00b1":[132,151,159],"3.8%,":[133],".05),":[136],"did":[138],"change":[140],"MICE.":[142],"Sit":[143],"stand":[145],"similarly":[147],"(27.2":[150],"6.1%,":[152],".05)":[155],"(21.5":[158],"5.4%,":[160],".05).":[163],"No":[164],"significant":[165],"changes":[166],"found":[168],"any":[174],"other":[175],"assessed.":[177],"CONCLUSION:":[178],"These":[179],"results":[180],"suggest":[181],"that":[182],"intensity":[184],"may":[185],"influence":[186],"training-induced":[187],"adaptation":[188],"aerobic":[193],"capacity":[194]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-12-13T00:00:00"}