{"id":"https://openalex.org/W2992740198","doi":"https://doi.org/10.1007/s00228-019-02788-w","title":"Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial","display_name":"Effect of magnesium supplementation on lactate clearance in critically ill patients with severe sepsis: a randomized clinical trial","publication_year":2019,"publication_date":"2019-12-09","ids":{"openalex":"https://openalex.org/W2992740198","doi":"https://doi.org/10.1007/s00228-019-02788-w","mag":"2992740198","pmid":"https://pubmed.ncbi.nlm.nih.gov/31814044"},"language":"en","primary_location":{"id":"doi:10.1007/s00228-019-02788-w","doi":"https://doi.org/10.1007/s00228-019-02788-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00228-019-02788-w","pdf_url":null,"source":{"id":"https://openalex.org/S31780008","display_name":"European Journal of Clinical Pharmacology","issn_l":"0031-6970","issn":["0031-6970","1432-1041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023828946","display_name":"Afsaneh Noormandi","orcid":"https://orcid.org/0000-0002-8479-0497","observed_orcids":["https://orcid.org/0000-0002-8479-0497"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Afsaneh Noormandi","raw_affiliation_strings":["Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065894925","display_name":"Hossein Khalili","orcid":"https://orcid.org/0000-0002-1590-6396","observed_orcids":["https://orcid.org/0000-0002-1590-6396"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Hossein Khalili","raw_affiliation_strings":["Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran. khalilih@tums.ac.ir","Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran"],"raw_orcid":"https://orcid.org/0000-0002-1590-6396","affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran. khalilih@tums.ac.ir","institution_ids":["https://openalex.org/I70640408"]},{"raw_affiliation_string":"Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box: 14155/6451, Tehran, 1417614411, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064706840","display_name":"Mostafa Mohammadi","orcid":"https://orcid.org/0000-0002-7084-0182","observed_orcids":["https://orcid.org/0000-0002-7084-0182"]},"institutions":[{"id":"https://openalex.org/I2800596343","display_name":"Imam Khomeini Hospital","ror":"https://ror.org/05v2x6b69","country_code":"IR","type":"healthcare","lineage":["https://openalex.org/I2800596343","https://openalex.org/I70640408"]},{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mostafa Mohammadi","raw_affiliation_strings":["Department of Intensive Care Unit, Imam Khomeini Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care Unit, Imam Khomeini Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I2800596343","https://openalex.org/I70640408"]}]},{"author_position":"last","author":{"id":null,"display_name":"Alireza Abdollahi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Alireza Abdollahi","raw_affiliation_strings":["Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5065894925"],"corresponding_institution_ids":["https://openalex.org/I70640408"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":2.4209,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.88897807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"76","issue":"2","first_page":"175","last_page":"184"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12280","display_name":"Magnesium in Health and Disease","score":0.04800000041723251,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnesium-supplementation","display_name":"magnesium supplementation","score":0.9819999933242798},{"id":"https://openalex.org/keywords/magnesium-sulfate","display_name":"magnesium sulfate","score":0.8820000290870667},{"id":"https://openalex.org/keywords/lactate-clearance","display_name":"lactate clearance","score":0.9819999933242798},{"id":"https://openalex.org/keywords/severe-sepsis","display_name":"severe sepsis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.9760000109672546},{"id":"https://openalex.org/keywords/serum-magnesium","display_name":"serum magnesium","score":0.7279999852180481},{"id":"https://openalex.org/keywords/sepsis-mortality","display_name":"sepsis mortality","score":0.7870000004768372},{"id":"https://openalex.org/keywords/icu-length-of-stay","display_name":"ICU length of stay","score":0.7490000128746033},{"id":"https://openalex.org/keywords/intravenous-magnesium","display_name":"intravenous magnesium","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C543218039","wikidata":"https://www.wikidata.org/wiki/Q660","display_name":"Magnesium","level":2,"score":0.7952898740768433},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7893321514129639},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.7131997346878052},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.7041239738464355},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.5595003962516785},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4823269546031952},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4815419316291809},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4701148569583893},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4540936350822449},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.43334531784057617},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.06252390146255493},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007362","descriptor_name":"Intensive Care Units","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D007902","descriptor_name":"Length of Stay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008278","descriptor_name":"Magnesium Sulfate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008278","descriptor_name":"Magnesium Sulfate","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008278","descriptor_name":"Magnesium Sulfate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D061605","descriptor_name":"Administration, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00228-019-02788-w","doi":"https://doi.org/10.1007/s00228-019-02788-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00228-019-02788-w","pdf_url":null,"source":{"id":"https://openalex.org/S31780008","display_name":"European Journal of Clinical Pharmacology","issn_l":"0031-6970","issn":["0031-6970","1432-1041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical Pharmacology","raw_type":"journal-article"},{"id":"pmid:31814044","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31814044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of clinical pharmacology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W106417294","https://openalex.org/W1576435157","https://openalex.org/W1587357481","https://openalex.org/W1915836761","https://openalex.org/W1986360229","https://openalex.org/W1998437727","https://openalex.org/W2006421326","https://openalex.org/W2007131833","https://openalex.org/W2087916276","https://openalex.org/W2103861359","https://openalex.org/W2114273947","https://openalex.org/W2119003509","https://openalex.org/W2126553012","https://openalex.org/W2134909543","https://openalex.org/W2198824178","https://openalex.org/W2306824567","https://openalex.org/W2442246762","https://openalex.org/W2529263277","https://openalex.org/W2529528719","https://openalex.org/W2595607582","https://openalex.org/W2724203315","https://openalex.org/W2733833714","https://openalex.org/W2755447372","https://openalex.org/W2757089737","https://openalex.org/W2767929859","https://openalex.org/W2773117682","https://openalex.org/W2799592883","https://openalex.org/W2799903692","https://openalex.org/W2802106280","https://openalex.org/W2805020527","https://openalex.org/W2884987392","https://openalex.org/W2888961094","https://openalex.org/W2902218078","https://openalex.org/W3023757607"],"related_works":["https://openalex.org/W7161796658","https://openalex.org/W7163188203","https://openalex.org/W2954603495","https://openalex.org/W7140176101","https://openalex.org/W4411380766","https://openalex.org/W4393861455","https://openalex.org/W4388002766","https://openalex.org/W4390026280","https://openalex.org/W3139491707","https://openalex.org/W2114273947"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-13T00:00:00"}