{"id":"https://openalex.org/W2992201181","doi":"https://doi.org/10.1089/ten.tea.2018.0308","title":"Three-Dimensional Culture of Salivary Gland Stem Cell in Orthotropic Decellularized Extracellular Matrix Hydrogels","display_name":"Three-Dimensional Culture of Salivary Gland Stem Cell in Orthotropic Decellularized Extracellular Matrix Hydrogels","publication_year":2019,"publication_date":"2019-01-11","ids":{"openalex":"https://openalex.org/W2992201181","doi":"https://doi.org/10.1089/ten.tea.2018.0308","mag":"2992201181","pmid":"https://pubmed.ncbi.nlm.nih.gov/30632466"},"language":"en","primary_location":{"id":"doi:10.1089/ten.tea.2018.0308","doi":"https://doi.org/10.1089/ten.tea.2018.0308","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.tea.2018.0308","pdf_url":null,"source":{"id":"https://openalex.org/S19081469","display_name":"Tissue Engineering Part A","issn_l":"1937-3341","issn":["1937-3341","1937-335X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part A","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049791239","display_name":"Kyungshin Shin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]},{"id":"https://openalex.org/I4210088603","display_name":"Korea Institute of Radiological and Medical Sciences","ror":"https://ror.org/00a8tg325","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210088603"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyungshin Shin","raw_affiliation_strings":["Department of Biotechnology, Korea University, Seoul, Republic of Korea","Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Korea University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210088603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015148383","display_name":"Kyung Hee Koo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088603","display_name":"Korea Institute of Radiological and Medical Sciences","ror":"https://ror.org/00a8tg325","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210088603"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyung Hee Koo","raw_affiliation_strings":["Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210088603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101532426","display_name":"Jaemin Jeong","orcid":"https://orcid.org/0000-0001-9758-7917","observed_orcids":["https://orcid.org/0000-0001-9758-7917"]},"institutions":[{"id":"https://openalex.org/I4210142845","display_name":"Hanyang University Seoul Hospital","ror":"https://ror.org/04n76mm80","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210142845","https://openalex.org/I4210152466","https://openalex.org/I4575257"]},{"id":"https://openalex.org/I4575257","display_name":"Hanyang University","ror":"https://ror.org/046865y68","country_code":"KR","type":"education","lineage":["https://openalex.org/I4575257"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jaemin Jeong","raw_affiliation_strings":["Department of Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210142845","https://openalex.org/I4575257"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014857464","display_name":"Sang Jun Park","orcid":"https://orcid.org/0000-0003-0542-2758","observed_orcids":["https://orcid.org/0000-0003-0542-2758"]},"institutions":[{"id":"https://openalex.org/I4210088603","display_name":"Korea Institute of Radiological and Medical Sciences","ror":"https://ror.org/00a8tg325","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210088603"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Jun Park","raw_affiliation_strings":["Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210088603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103553057","display_name":"Dong Jin Choi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088603","display_name":"Korea Institute of Radiological and Medical Sciences","ror":"https://ror.org/00a8tg325","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210088603"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dong Jin Choi","raw_affiliation_strings":["Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210088603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113581452","display_name":"Young\u2010Gyu Ko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young-Gyu Ko","raw_affiliation_strings":["Department of Life Sciences, Korea University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences, Korea University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089683343","display_name":"Heechung Kwon","orcid":"https://orcid.org/0000-0001-7193-866X","observed_orcids":["https://orcid.org/0000-0001-7193-866X"]},"institutions":[{"id":"https://openalex.org/I4210088603","display_name":"Korea Institute of Radiological and Medical Sciences","ror":"https://ror.org/00a8tg325","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210088603"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Heechung Kwon","raw_affiliation_strings":["Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210088603"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5089683343"],"corresponding_institution_ids":["https://openalex.org/I4210088603"],"apc_list":null,"apc_paid":null,"fwci":2.5815,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.88433107,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"25","issue":"19-20","first_page":"1396","last_page":"1403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9624000191688538,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.010099999606609344,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/salivary-gland-stem-cells","display_name":"salivary gland stem cells","score":0.9359999895095825},{"id":"https://openalex.org/keywords/3d-cell-culture","display_name":"3D cell culture","score":0.7630000114440918},{"id":"https://openalex.org/keywords/hyposalivation","display_name":"hyposalivation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/radiotherapy-complications","display_name":"radiotherapy complications","score":0.7099999785423279},{"id":"https://openalex.org/keywords/salivary-gland-regeneration","display_name":"salivary gland regeneration","score":0.8679999709129333},{"id":"https://openalex.org/keywords/organoids","display_name":"organoids","score":0.5669999718666077},{"id":"https://openalex.org/keywords/salivary-gland-differentiation","display_name":"salivary gland differentiation","score":0.6859999895095825},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.7609999775886536},{"id":"https://openalex.org/keywords/thyroid-cancer","display_name":"thyroid cancer","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.9846535325050354},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.8191614151000977},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7606847286224365},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5991548895835876},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5398089289665222},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.5244339108467102},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.510574221611023},{"id":"https://openalex.org/C131336679","wikidata":"https://www.wikidata.org/wiki/Q901006","display_name":"Orthotropic material","level":3,"score":0.48117977380752563},{"id":"https://openalex.org/C2778937882","wikidata":"https://www.wikidata.org/wiki/Q134938","display_name":"Salivary gland","level":2,"score":0.4698913097381592},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.4571629762649536},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4420817792415619},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.4247654676437378},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3812240660190582},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2625204920768738},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26068586111068726},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2388014793395996},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.15760335326194763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14621341228485107},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10697335004806519},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.10398778319358826},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.0987926721572876},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012212","descriptor_name":"Rheology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012469","descriptor_name":"Salivary Glands","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018929","descriptor_name":"Cell Culture Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/ten.tea.2018.0308","doi":"https://doi.org/10.1089/ten.tea.2018.0308","is_oa":false,"landing_page_url":"https://doi.org/10.1089/ten.tea.2018.0308","pdf_url":null,"source":{"id":"https://openalex.org/S19081469","display_name":"Tissue Engineering Part A","issn_l":"1937-3341","issn":["1937-3341","1937-335X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering Part A","raw_type":"journal-article"},{"id":"pmid:30632466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30632466","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue engineering. Part A","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1541104889","https://openalex.org/W1563959780","https://openalex.org/W1967807152","https://openalex.org/W1969432048","https://openalex.org/W1983023703","https://openalex.org/W1985190299","https://openalex.org/W1993222048","https://openalex.org/W1994077842","https://openalex.org/W2015375064","https://openalex.org/W2016736959","https://openalex.org/W2035489526","https://openalex.org/W2049786111","https://openalex.org/W2055549058","https://openalex.org/W2079312215","https://openalex.org/W2082946068","https://openalex.org/W2095830273","https://openalex.org/W2101228997","https://openalex.org/W2109939725","https://openalex.org/W2118772763","https://openalex.org/W2119727448","https://openalex.org/W2133683725","https://openalex.org/W2134244003","https://openalex.org/W2149411938","https://openalex.org/W2221253621","https://openalex.org/W2275788189","https://openalex.org/W2279282310","https://openalex.org/W2464973239","https://openalex.org/W2468452764","https://openalex.org/W2538427375","https://openalex.org/W2562305856","https://openalex.org/W2801200955"],"related_works":["https://openalex.org/W1985190299","https://openalex.org/W4309360881","https://openalex.org/W2165633058","https://openalex.org/W2138718282","https://openalex.org/W2507405703","https://openalex.org/W2072291394","https://openalex.org/W2264749951","https://openalex.org/W4312855378","https://openalex.org/W3037689511","https://openalex.org/W2996874347"],"abstract_inverted_index":{"Radiotherapy":[0],"in":[1,50,113,135,175,177,230],"patients":[2,20],"with":[3,21],"cancer":[4,7,25],"can":[5],"kill":[6],"cells":[8,13,105],"but":[9],"also":[10],"damage":[11],"normal":[12],"or":[14,26,98],"tissues.":[15],"During":[16],"the":[17,71,114,154,185,240,254,270,273],"treatment":[18],"of":[19,36,44,126,133,143,157,199,256,272,282],"head":[22],"and":[23,101,120,129,151,196,221,252],"neck":[24],"thyroid":[27],"cancer,":[28],"hyposalivation":[29,45],"is":[30,46],"a":[31,82,197,215,260,276],"representative":[32],"chronic":[33],"side":[34],"effect":[35],"radio-damaged":[37,228,283],"salivary":[38,243],"glands":[39],"(SGs).":[40],"The":[41],"major":[42],"symptom":[43],"mouth":[47],"dryness,":[48],"resulting":[49],"several":[51],"subsequent":[52],"long-term":[53],"complications.":[54],"No":[55],"effective":[56],"therapeutic":[57],"approaches":[58],"have":[59],"been":[60],"developed":[61,70],"to":[62,110,165,168,209,226],"manage":[63,227],"this":[64,67,236,257],"symptom.":[65],"In":[66,235],"study,":[68,237],"we":[69,238],"first":[72,241],"rat":[73,102,242],"SG":[74,89,103,122,171,200,210],"tissue-derived":[75,246],"decellularized":[76,247],"extracellular":[77,248],"matrix":[78,249,278],"hydrogel":[79,250,258],"(DSGM-hydrogel)":[80,251],"as":[81,214,259,275],"functional":[83,123,261],"orthotropic":[84,262],"bioscaffold":[85],"for":[86,192,218,222,279],"future":[87],"efficient":[88],"stem":[90,211],"cell":[91,194,212],"therapy.":[92],"DSGM-hydrogels":[93,176,186],"were":[94,107,163],"characterized":[95],"by":[96],"rheological":[97],"biochemical":[99],"analyses,":[100],"stem/progenitor":[104,146,193],"(rSGSCs)":[106],"then":[108],"subjected":[109],"three-dimensional":[111],"culture":[112,174],"DSGM-hydrogels.":[115],"Interestingly,":[116],"DSGM-hydrogel-embedded":[117],"rSGSCs":[118],"survived":[119],"expressed":[121],"differentiation":[124],"marker":[125],"amylase":[127],"IA":[128],"increased":[130],"enzyme":[131],"activity":[132],"\u03b1-amylase":[134],"protein":[136],"level,":[137],"whereas":[138],"they":[139],"showed":[140],"reduced":[141],"levels":[142,156,166],"adult":[144],"ductal":[145],"markers,":[147],"including":[148],"c-Kit,":[149],"c-Met,":[150],"CD44.":[152],"Furthermore,":[153],"expression":[155],"basic":[158],"epithelial":[159],"tight":[160],"junction":[161],"markers":[162],"recovered":[164],"similar":[167],"those":[169],"naked":[170],"tissues":[172],"after":[173],"transcription":[178],"level.":[179],"Therefore,":[180],"our":[181],"findings":[182,265],"suggested":[183],"that":[184],"could":[187,204],"provide":[188,266],"an":[189,206,219],"appropriate":[190],"microenvironment":[191],"survival":[195],"source":[198,217],"cytodifferentiation.":[201],"This":[202],"approach":[203],"be":[205],"applicable":[207],"method":[208],"research":[213],"potential":[216],"organoid":[220],"clinical":[223],"regenerative":[224,280],"reagents":[225],"SGs":[229],"vivo":[231],".":[232],"Impact":[233],"Statement":[234],"established":[239],"gland":[244],"(SG)":[245],"assessed":[253],"role":[255],"bioscaffold.":[263],"Our":[264],"important":[267],"insights":[268],"into":[269],"applications":[271],"DSGM-hydrogel":[274],"biocompatible":[277],"therapy":[281],"SGs.":[284]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-12-13T00:00:00"}
