{"id":"https://openalex.org/W2991701006","doi":"https://doi.org/10.1016/j.bjan.2019.09.007","title":"Associa\u00e7\u00e3o entre perfus\u00e3o perif\u00e9rica, microcircula\u00e7\u00e3o e mortalidade em sepse: uma revis\u00e3o sistem\u00e1tica","display_name":"Associa\u00e7\u00e3o entre perfus\u00e3o perif\u00e9rica, microcircula\u00e7\u00e3o e mortalidade em sepse: uma revis\u00e3o sistem\u00e1tica","publication_year":2019,"publication_date":"2019-11-01","ids":{"openalex":"https://openalex.org/W2991701006","doi":"https://doi.org/10.1016/j.bjan.2019.09.007","mag":"2991701006"},"language":"pt","primary_location":{"id":"doi:10.1016/j.bjan.2019.09.007","doi":"https://doi.org/10.1016/j.bjan.2019.09.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bjan.2019.09.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S003470941930368X/pdf","source":{"id":"https://openalex.org/S100946473","display_name":"Brazilian Journal of Anesthesiology","issn_l":"0034-7094","issn":["0034-7094","1806-907X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian Journal of Anesthesiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.sciencedirect.com/science/article/pii/S003470941930368X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017746987","display_name":"Danillo Menezes dos Santos","orcid":"https://orcid.org/0000-0002-6075-6147","observed_orcids":["https://orcid.org/0000-0002-6075-6147"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Danillo Menezes dos Santos","raw_affiliation_strings":["Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073188396","display_name":"Jullyana de Souza Siqueira Quintans","orcid":"https://orcid.org/0000-0001-6507-8982","observed_orcids":["https://orcid.org/0000-0001-6507-8982"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jullyana S.S. Quintans","raw_affiliation_strings":["Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072217846","display_name":"Lucindo Jos\u00e9 Quintans\u2010J\u00fanior","orcid":"https://orcid.org/0000-0001-5155-938X","observed_orcids":["https://orcid.org/0000-0001-5155-938X"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lucindo J. Quintans\u2010Junior","raw_affiliation_strings":["Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016275096","display_name":"Valter Joviniano Santana\u2010Filho","orcid":"https://orcid.org/0000-0003-1488-0259","observed_orcids":["https://orcid.org/0000-0003-1488-0259"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Valter J. Santana\u2010Filho","raw_affiliation_strings":["Universidade Federal de Sergipe, N\u00facleo de Fisioterapia, Aracaju, SE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Sergipe, N\u00facleo de Fisioterapia, Aracaju, SE, Brasil","institution_ids":["https://openalex.org/I190085865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113729847","display_name":"Cl\u00e1udio L. Pereira da Cunha","orcid":"https://orcid.org/0000-0002-2806-743X","observed_orcids":["https://orcid.org/0000-0002-2806-743X"]},"institutions":[{"id":"https://openalex.org/I4210134516","display_name":"Hospital de Cl\u00ednicas Universidade Federal do Paran\u00e1","ror":"https://ror.org/03ej9xm26","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210134516"]},{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cl\u00e1udio Leinig Pereira da Cunha","raw_affiliation_strings":["Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil","institution_ids":["https://openalex.org/I4210134516","https://openalex.org/I52418104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029327556","display_name":"Igor Alexandre C\u00f4rtes de Menezes","orcid":"https://orcid.org/0000-0001-9270-0079","observed_orcids":["https://orcid.org/0000-0001-9270-0079"]},"institutions":[{"id":"https://openalex.org/I4210134516","display_name":"Hospital de Cl\u00ednicas Universidade Federal do Paran\u00e1","ror":"https://ror.org/03ej9xm26","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210134516"]},{"id":"https://openalex.org/I52418104","display_name":"Universidade Federal do Paran\u00e1","ror":"https://ror.org/05syd6y78","country_code":"BR","type":"education","lineage":["https://openalex.org/I52418104"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Igor Alexandre Cortes Menezes","raw_affiliation_strings":["Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil. Electronic address: igoracmenezes1@gmail.com","Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil"],"raw_orcid":"https://orcid.org/0000-0001-9270-0079","affiliations":[{"raw_affiliation_string":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil. Electronic address: igoracmenezes1@gmail.com","institution_ids":["https://openalex.org/I4210134516","https://openalex.org/I52418104"]},{"raw_affiliation_string":"Universidade Federal do Paran\u00e1, Hospital de Cl\u00ednicas, Curitiba, PR, Brasil","institution_ids":["https://openalex.org/I4210134516","https://openalex.org/I52418104"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060671190","display_name":"M\u00e1rcio Roberto Viana dos Santos","orcid":"https://orcid.org/0000-0002-9458-0370","observed_orcids":["https://orcid.org/0000-0002-9458-0370"]},"institutions":[{"id":"https://openalex.org/I190085865","display_name":"Universidade Federal de Sergipe","ror":"https://ror.org/028ka0n85","country_code":"BR","type":"education","lineage":["https://openalex.org/I190085865"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M\u00e1rcio R. Viana Santos","raw_affiliation_strings":["Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Sergipe, Departamento de Fisiologia, S\u00e3o Crist\u00f3v\u00e3o, SE, Brasil","institution_ids":["https://openalex.org/I190085865"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5029327556"],"corresponding_institution_ids":["https://openalex.org/I4210134516","https://openalex.org/I52418104"],"apc_list":null,"apc_paid":null,"fwci":0.1627,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.20115607,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"69","issue":"6","first_page":"605","last_page":"621"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12333","display_name":"Abdominal Surgery and Complications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/peripheral-perfusion","display_name":"peripheral perfusion","score":0.953000009059906},{"id":"https://openalex.org/keywords/microcirculation","display_name":"microcirculation","score":0.9449999928474426},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8259999752044678},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.722000002861023},{"id":"https://openalex.org/keywords/near-infrared-spectroscopy","display_name":"near-infrared spectroscopy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/sidestream-dark-field-imaging","display_name":"sidestream dark field imaging","score":0.9240000247955322},{"id":"https://openalex.org/keywords/sublingual-microcirculation","display_name":"sublingual microcirculation","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hypoperfusion","display_name":"hypoperfusion","score":0.8169999718666077},{"id":"https://openalex.org/keywords/sepsis-severity","display_name":"sepsis severity","score":0.4620000123977661},{"id":"https://openalex.org/keywords/organ-dysfunction","display_name":"organ dysfunction","score":0.3959999978542328},{"id":"https://openalex.org/keywords/sepsis-severity-score","display_name":"sepsis severity score","score":0.382999986410141},{"id":"https://openalex.org/keywords/lactate","display_name":"lactate","score":0.3160000145435333},{"id":"https://openalex.org/keywords/vasopressors","display_name":"vasopressors","score":0.4659999907016754},{"id":"https://openalex.org/keywords/fluid-resuscitation","display_name":"fluid resuscitation","score":0.6000000238418579},{"id":"https://openalex.org/keywords/sepsis-mortality","display_name":"sepsis mortality","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5604718327522278}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bjan.2019.09.007","doi":"https://doi.org/10.1016/j.bjan.2019.09.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bjan.2019.09.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S003470941930368X/pdf","source":{"id":"https://openalex.org/S100946473","display_name":"Brazilian Journal of Anesthesiology","issn_l":"0034-7094","issn":["0034-7094","1806-907X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian Journal of Anesthesiology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bjan.2019.09.007","doi":"https://doi.org/10.1016/j.bjan.2019.09.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bjan.2019.09.007","pdf_url":"https://www.sciencedirect.com/science/article/pii/S003470941930368X/pdf","source":{"id":"https://openalex.org/S100946473","display_name":"Brazilian Journal of Anesthesiology","issn_l":"0034-7094","issn":["0034-7094","1806-907X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian Journal of Anesthesiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320323353","display_name":"Funda\u00e7\u00e3o de Apoio \u00e0 Pesquisa e \u00e0 Inova\u00e7\u00e3o Tecnol\u00f3gica do Estado de Sergipe","ror":"https://ror.org/028ka0n85"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2991701006.pdf","grobid_xml":"https://content.openalex.org/works/W2991701006.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W35572208","https://openalex.org/W1754819523","https://openalex.org/W1769566588","https://openalex.org/W1957312998","https://openalex.org/W1964504290","https://openalex.org/W1966142159","https://openalex.org/W1969367601","https://openalex.org/W1981194791","https://openalex.org/W1995485815","https://openalex.org/W2006216692","https://openalex.org/W2014607721","https://openalex.org/W2025813381","https://openalex.org/W2025856938","https://openalex.org/W2033070593","https://openalex.org/W2040159339","https://openalex.org/W2048876919","https://openalex.org/W2050498531","https://openalex.org/W2052869355","https://openalex.org/W2057364247","https://openalex.org/W2058678563","https://openalex.org/W2060568666","https://openalex.org/W2063603479","https://openalex.org/W2065926238","https://openalex.org/W2078546046","https://openalex.org/W2080347627","https://openalex.org/W2080552527","https://openalex.org/W2099417642","https://openalex.org/W2100667410","https://openalex.org/W2106282197","https://openalex.org/W2111364530","https://openalex.org/W2121933145","https://openalex.org/W2136372320","https://openalex.org/W2149592972","https://openalex.org/W2156125520","https://openalex.org/W2157684852","https://openalex.org/W2160967251","https://openalex.org/W2170988901","https://openalex.org/W2174224245","https://openalex.org/W2294908710","https://openalex.org/W2328648962","https://openalex.org/W2339828706","https://openalex.org/W2404727847","https://openalex.org/W2410994363","https://openalex.org/W2419156105","https://openalex.org/W2466129126","https://openalex.org/W2581605534","https://openalex.org/W2581953275","https://openalex.org/W2602406480","https://openalex.org/W2607389742","https://openalex.org/W2770186315","https://openalex.org/W2788885667","https://openalex.org/W2912774204","https://openalex.org/W3016555942"],"related_works":["https://openalex.org/W4400494180","https://openalex.org/W2982849011","https://openalex.org/W4406090063","https://openalex.org/W2908346898","https://openalex.org/W4402201331","https://openalex.org/W4282915129","https://openalex.org/W2900845672","https://openalex.org/W6940017145","https://openalex.org/W4308774962","https://openalex.org/W2571870846"],"abstract_inverted_index":{"Embora":[0],"evid\u00eancias":[1],"crescentes":[2],"apoiem":[3],"a":[4,19,24,34,78,141,175,189,208,423,429,483,522,528],"monitora\u00e7\u00e3o":[5],"da":[6,21,252,271,277],"perfus\u00e3o":[7,26,68,142,232],"perif\u00e9rica":[8,82,233],"em":[9,85,193,243],"pacientes":[10,128,151],"s\u00e9pticos,":[11],"nenhuma":[12],"revis\u00e3o":[13,145],"sistem\u00e1tica":[14],"foi":[15,44,207,248],"feita":[16,45],"para":[17,46,139,261],"explorar":[18],"for\u00e7a":[20],"associa\u00e7\u00e3o":[22,79,265],"entre":[23,80,159,230],"m\u00e1":[25,231],"avaliada":[27],"na":[28,177,281],"microcircula\u00e7\u00e3o":[29,66,209],"dos":[30,222],"tecidos":[31],"perif\u00e9ricos":[32,247],"e":[33,67,83,113,161,188,234],"mortalidade.":[35,235,253],"Uma":[36],"busca":[37],"nas":[38],"bases":[39],"de":[40,52,72,89,96,104,109,150,157,169,191,240,279],"dados":[41],"mais":[42,171,205],"importantes":[43],"encontrar":[47],"artigos":[48,95,111,114,124],"publicados":[49],"at\u00e9":[50],"fevereiro":[51],"2018":[53,334],"que":[54,76,115],"correspondessem":[55],"aos":[56],"crit\u00e9rios":[57,71,88],"deste":[58],"estudo,":[59],"com":[60,99,129,133,154],"diferentes":[61],"palavras\u2010chave:":[62],"sepse,":[63],"mortalidade,":[64],"progn\u00f3stico,":[65],"perif\u00e9rica.":[69,143],"Os":[70,87,167],"inclus\u00e3o":[73],"foram":[74,92,131,174],"estudos":[75,98,223,256],"avaliaram":[77],"perfus\u00e3o/microcircula\u00e7\u00e3o":[81],"mortalidade":[84,158],"sepse.":[86,282],"exclus\u00e3o":[90],"adotados":[91],"os":[93],"seguintes:":[94],"revis\u00e3o,":[97],"animais/pr\u00e9\u2010cl\u00ednicos,":[100],"metan\u00e1lises,":[101],"resumos,":[102],"anais":[103],"congressos,":[105],"editoriais,":[106],"cartas,":[107],"relatos":[108],"casos,":[110],"duplicados":[112],"n\u00e3o":[116,245],"continham":[117],"resumos":[118],"e/ou":[119],"texto.":[120],"Foram":[121],"selecionados":[122],"26":[123,398],"nos":[125],"quais":[126],"2465":[127,404],"sepse":[130],"avaliados":[132],"pelo":[134],"menos":[135],"um":[136,147,269,274],"m\u00e9todo":[137],"reconhecido":[138],"monitorar":[140],"A":[144,220,318],"demonstrou":[146,226],"grupo":[148],"heterog\u00eaneo":[149],"gravemente":[152],"enfermos":[153],"uma":[155,227],"taxa":[156],"3%":[160,432],"71%":[162,434],"(mediana":[163],"=":[164,436],"37%":[165,437],"[28%\u201043%]).":[166],"m\u00e9todos":[168],"avalia\u00e7\u00e3o":[170],"comumente":[172],"usados":[173],"espectroscopia":[176],"regi\u00e3o":[178],"do":[179,216],"infravermelho":[180],"pr\u00f3ximo":[181],"(Near\u2010Infrared":[182],"Spectroscopy":[183,448],"\u2013":[184,198],"NIRS)":[185],"(7":[186,450],"artigos)":[187,225],"an\u00e1lise":[190],"imagens":[192],"campo":[194],"escuro":[195],"(Sidestream":[196],"Dark\u2010Field":[197,454],"SDF)":[199],"(5":[200,457],"artigos).":[201,219],"O":[202],"leito":[203],"vascular":[204,460],"avaliado":[206],"sublingual/bucal":[210],"(8":[211,468],"artigos),":[212],"seguida":[213],"pela":[214],"ponta":[215],"dedo":[217],"(4":[218,473],"maioria":[221],"(23":[224,480],"clara":[228],"rela\u00e7\u00e3o":[229],"Em":[236],"conclus\u00e3o,":[237],"o":[238],"diagn\u00f3stico":[239],"hipoperfus\u00e3o/anormalidades":[241],"microcirculat\u00f3rias":[242],"\u00f3rg\u00e3os":[244,280],"vitais":[246],"associado":[249],"ao":[250],"aumento":[251],"No":[254],"entanto,":[255],"adicionais":[257],"devem":[258],"ser":[259,267],"feitos":[260],"verificar":[262],"se":[263],"essa":[264],"pode":[266],"considerada":[268],"marcador":[270],"gravidade":[272],"ou":[273],"fator":[275],"desencadeante":[276],"fal\u00eancia":[278],"Although":[283],"increasing":[284],"evidence":[285],"supports":[286],"the":[287,303,321,337,397,465,478,494,525],"monitoring":[288,417],"of":[289,305,313,320,339,379,477,496,524],"peripheral":[290,314,350,361,418,488,500],"perfusion":[291,309,489],"in":[292,311,365,402,499,534],"septic":[293],"patients,":[294],"no":[295,394],"systematic":[296],"review":[297,372,421],"has":[298],"been":[299],"undertaken":[300,513],"to":[301,328,514],"explore":[302],"strength":[304],"association":[306,359,518],"between":[307,360,431,486],"poor":[308,487],"assessed":[310,358],"microcirculation":[312,348,467],"tissues":[315],"and":[316,349,363,385,433,452,490],"mortality.":[317,491,507],"search":[319],"most":[322,440,462],"important":[323],"databases":[324],"was":[325,464,503],"carried":[326],"out":[327],"find":[329],"articles":[330,386,399],"published":[331],"until":[332],"February":[333],"that":[335,357,387],"met":[336],"criteria":[338,354,369],"this":[340,517],"study":[341],"using":[342,410],"different":[343],"keywords:":[344],"sepsis,":[345],"mortality,":[346],"prognosis,":[347],"perfusion.":[351,419],"The":[352,367,420,439,459,475],"inclusion":[353],"were":[355,400,408,446],"studies":[356,479,510],"perfusion/microcirculation":[362],"mortality":[364],"sepsis.":[366,535],"exclusion":[368],"adopted":[370],"were:":[371],"articles,":[373],"animal/pre\u2010clinical":[374],"studies,":[375],"meta\u2010analyzes,":[376],"abstracts,":[377],"annals":[378],"congress,":[380],"editorials,":[381],"letters,":[382],"case\u2010reports,":[383],"duplicate":[384],"did":[388],"not":[389],"present":[390],"abstracts":[391],"and/or":[392],"had":[393],"text.":[395],"In":[396,492],"chosen":[401],"which":[403],"patients":[405],"with":[406,428,505],"sepsis":[407],"evaluated":[409],"at":[411],"least":[412],"one":[413],"recognized":[414],"method":[415],"for":[416,444,531],"demonstrated":[422,482],"heterogeneous":[424],"critically":[425],"ill":[426],"group":[427],"mortality\u2010rate":[430],"(median":[435],"[28%\u201343%]).":[438],"commonly":[441],"used":[442],"methods":[443],"measurement":[445],"Near\u2010Infrared":[447],"(NIRS)":[449],"articles)":[451,481],"Sidestream":[453],"(SDF)":[455],"imaging":[456],"articles).":[458,474],"bed":[461],"studied":[463],"sublingual/buccal":[466],"articles),":[469],"followed":[470],"by":[471],"fingertip":[472],"majority":[476],"clear":[484],"relationship":[485],"conclusion,":[493],"diagnosis":[495],"hypoperfusion/microcirculatory":[497],"abnormalities":[498],"non\u2010vital":[501],"organs":[502],"associated":[504],"increased":[506],"However,":[508],"additional":[509],"must":[511],"be":[512,520],"verify":[515],"if":[516],"can":[519],"considered":[521],"marker":[523],"gravity":[526],"or":[527],"trigger":[529],"factor":[530],"organ":[532],"failure":[533]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-13T00:00:00"}