{"id":"https://openalex.org/W2991200265","doi":null,"title":"How to train a mouse-methodological issues in pre-clinical exercise oncology.","display_name":"How to train a mouse-methodological issues in pre-clinical exercise oncology.","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2991200265","mag":"2991200265","pmid":"https://pubmed.ncbi.nlm.nih.gov/31285956","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6610064"},"language":"en","primary_location":{"id":"pmid:31285956","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31285956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cancer research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6610064/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013561260","display_name":"Luma Melo","orcid":"https://orcid.org/0000-0003-2240-7787","observed_orcids":["https://orcid.org/0000-0003-2240-7787"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luma Melo","raw_affiliation_strings":["Department of Environmental Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA","Department of History & Philosophy of Science & Medicine, Indiana University Bloomington, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, School of Public Health, Indiana University, Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of History & Philosophy of Science & Medicine, Indiana University Bloomington, IN, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026774283","display_name":"Amit Hagar","orcid":"https://orcid.org/0000-0002-7920-975X","observed_orcids":["https://orcid.org/0000-0002-7920-975X"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amit Hagar","raw_affiliation_strings":["Department of Environmental Health, School of Public Health, Indiana University Bloomington, IN 47405, USA","Department of Intelligent Systems Engineering, Indiana University Bloomington, IN, USA","Department of History & Philosophy of Science & Medicine, Indiana University Bloomington, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Health, School of Public Health, Indiana University Bloomington, IN 47405, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of Intelligent Systems Engineering, Indiana University Bloomington, IN, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"raw_affiliation_string":"Department of History & Philosophy of Science & Medicine, Indiana University Bloomington, IN, USA","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1611,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.74581476,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"9","issue":"6","first_page":"1246","last_page":"1253"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.45239999890327454,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.45239999890327454,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12281","display_name":"Animal testing and alternatives","score":0.2085999995470047,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.05719999969005585,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exercise-oncology","display_name":"exercise oncology","score":0.996999979019165},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5346433520317078},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5173680186271667},{"id":"https://openalex.org/C158154518","wikidata":"https://www.wikidata.org/wiki/Q7310970","display_name":"Relevance (law)","level":2,"score":0.42083317041397095},{"id":"https://openalex.org/C2776598537","wikidata":"https://www.wikidata.org/wiki/Q1812651","display_name":"Clinical Oncology","level":3,"score":0.41519221663475037},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3877023458480835},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3815539479255676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21734938025474548},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmid:31285956","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31285956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cancer research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6610064","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6610064/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cancer Res","raw_type":"Text"},{"id":"pmh:oai:iu.tind.io:2264","doi":null,"is_oa":false,"landing_page_url":"http://iu.tind.io/record/2264","pdf_url":null,"source":{"id":"https://openalex.org/S4306402656","display_name":"IUScholarWorks Open (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://iu.tind.io/record/2264","raw_type":"Text"},{"id":"mag:2991200265","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31285956","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6610064","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6610064/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cancer Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W49225998","https://openalex.org/W1496528573","https://openalex.org/W1549409082","https://openalex.org/W1964903369","https://openalex.org/W1974950104","https://openalex.org/W1979870505","https://openalex.org/W1989190637","https://openalex.org/W1991410461","https://openalex.org/W1994549184","https://openalex.org/W2007818439","https://openalex.org/W2009532375","https://openalex.org/W2019030744","https://openalex.org/W2022155486","https://openalex.org/W2030904822","https://openalex.org/W2031403711","https://openalex.org/W2073658789","https://openalex.org/W2086509130","https://openalex.org/W2095152426","https://openalex.org/W2096987797","https://openalex.org/W2104568311","https://openalex.org/W2110219786","https://openalex.org/W2114696686","https://openalex.org/W2115065909","https://openalex.org/W2121789107","https://openalex.org/W2142340251","https://openalex.org/W2146019567","https://openalex.org/W2148042563","https://openalex.org/W2148764339","https://openalex.org/W2155897243","https://openalex.org/W2182591962","https://openalex.org/W2203549709","https://openalex.org/W2315472919","https://openalex.org/W2330716957","https://openalex.org/W2402756356","https://openalex.org/W2473034500","https://openalex.org/W2493489412","https://openalex.org/W2576310876","https://openalex.org/W2593179916","https://openalex.org/W2605039992","https://openalex.org/W2770290353","https://openalex.org/W2792582996","https://openalex.org/W2948590113"],"related_works":["https://openalex.org/W7150996212","https://openalex.org/W4206928324","https://openalex.org/W3098141554","https://openalex.org/W7168094242","https://openalex.org/W2912145028","https://openalex.org/W2497894495","https://openalex.org/W3174592879","https://openalex.org/W4414548143","https://openalex.org/W4382516545","https://openalex.org/W2140090204"],"abstract_inverted_index":{"We":[0,119],"point":[1],"at":[2],"several":[3],"challenges":[4],"that":[5,46,65,126],"current":[6],"exercise":[7,25,90,123],"oncology":[8,26],"rodent":[9,124],"models":[10],"face,":[11],"which":[12],"call":[13],"their":[14,40],"human-relevance":[15],"into":[16,80],"question:":[17],"the":[18,59,63,85,93,105,114],"vast":[19],"majority":[20],"of":[21,53,88,95,130],"pre-clinical":[22,75],"studies":[23,76],"in":[24,101,113],"treat":[27],"\"physical":[28],"exercise\"":[29],"as":[30],"a":[31],"primitive":[32],"concept":[33],"without":[34],"further":[35],"analysis":[36,54],"or":[37],"qualification,":[38],"and":[39,55,104],"results":[41],"are":[42],"based":[43],"on":[44,91],"dosages":[45],"no":[47],"human":[48],"can":[49],"endure.":[50],"The":[51],"lack":[52],"qualification":[56],"together":[57],"with":[58],"dosage":[60],"mismatch":[61],"conceal":[62],"fact":[64],"rodents":[66],"do":[67],"not":[68],"run":[69],"like":[70],"humans.":[71],"Consequently,":[72],"while":[73],"these":[74,132],"may":[77],"yield":[78],"insights":[79],"potential":[81],"biological":[82],"mechanisms":[83],"underlying":[84],"systemic":[86],"effects":[87],"physical":[89],"cancer,":[92],"applicability":[94],"this":[96],"knowledge":[97],"to":[98,107,110],"preventive":[99],"interventions":[100],"healthy":[102],"humans":[103],"ability":[106],"translate":[108],"it":[109],"practical":[111],"therapies":[112],"critically":[115],"ill":[116],"remain":[117],"limited.":[118],"propose":[120],"an":[121],"alternative":[122],"model":[125],"has":[127],"better":[128],"chances":[129],"meeting":[131],"challenges.":[133]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-12-05T00:00:00"}