{"id":"https://openalex.org/W2991158879","doi":null,"title":"Examining correlations of oxygen sensitive MRI (BOLD/TOLD) with [18F]FMISO PET in rat prostate tumors.","display_name":"Examining correlations of oxygen sensitive MRI (BOLD/TOLD) with [18F]FMISO PET in rat prostate tumors.","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2991158879","mag":"2991158879","pmid":"https://pubmed.ncbi.nlm.nih.gov/31139498","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6526364"},"language":"en","primary_location":{"id":"pmid:31139498","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31139498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of nuclear medicine and molecular imaging","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6526364/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113690224","display_name":"Heling Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heling Zhou","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079841646","display_name":"Srinivas Chiguru","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srinivas Chiguru","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001624932","display_name":"Rami R. Hallac","orcid":"https://orcid.org/0000-0001-9025-399X","observed_orcids":["https://orcid.org/0000-0001-9025-399X"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rami R Hallac","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","AIM Center, Children's Health Dallas, TX, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]},{"raw_affiliation_string":"AIM Center, Children's Health Dallas, TX, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018106832","display_name":"Donghan M. Yang","orcid":"https://orcid.org/0000-0003-1935-0214","observed_orcids":["https://orcid.org/0000-0003-1935-0214"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donghan Yang","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070272648","display_name":"Guiyang Hao","orcid":"https://orcid.org/0000-0001-6695-5123","observed_orcids":["https://orcid.org/0000-0001-6695-5123"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guiyang Hao","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015061264","display_name":"Peter Peschke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Peter Peschke","raw_affiliation_strings":["Medical Physics in Radiation Oncology, German Cancer Research Center Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Physics in Radiation Oncology, German Cancer Research Center Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090381580","display_name":"Ralph P. Mason","orcid":"https://orcid.org/0000-0001-7517-3721","observed_orcids":["https://orcid.org/0000-0001-7517-3721"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ralph P Mason","raw_affiliation_strings":["Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, UT Southwestern Medical Center Dallas, TX 75390-9058, USA","institution_ids":["https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5596,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.80930452,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"9","issue":"2","first_page":"156","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.4611999988555908,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.4611999988555908,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.2062000036239624,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.13369999825954437,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bold-mri","display_name":"BOLD MRI","score":0.9610000252723694},{"id":"https://openalex.org/keywords/18f-fluoromisonidazole","display_name":"18F-fluoromisonidazole","score":0.9160000085830688},{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.7329999804496765},{"id":"https://openalex.org/keywords/tumor-hypoxia","display_name":"tumor hypoxia","score":0.9079999923706055},{"id":"https://openalex.org/keywords/perfusion","display_name":"perfusion","score":0.5659999847412109},{"id":"https://openalex.org/keywords/regional-heterogeneity","display_name":"regional heterogeneity","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C2779081379","wikidata":"https://www.wikidata.org/wiki/Q7852677","display_name":"Tumor hypoxia","level":3,"score":0.7421553730964661},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6972998380661011},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.649720311164856},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5991965532302856},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.5897789001464844},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5425451993942261},{"id":"https://openalex.org/C2780238834","wikidata":"https://www.wikidata.org/wiki/Q796855","display_name":"Blood-oxygen-level dependent","level":3,"score":0.4405616521835327},{"id":"https://openalex.org/C39300077","wikidata":"https://www.wikidata.org/wiki/Q9530","display_name":"Breathing","level":2,"score":0.4319861829280853},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.36913520097732544},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3407231569290161},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.29399362206459045},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25725018978118896},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.16889038681983948},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15607285499572754},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:31139498","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31139498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of nuclear medicine and molecular imaging","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6526364","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6526364/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Nucl Med Mol Imaging","raw_type":"Text"},{"id":"mag:2991158879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31139498","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6526364","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6526364/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Nucl Med Mol Imaging","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9074000120162964,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2020088492","display_name":"Southwestern NMR Center for in Vivo Metabolism","funder_award_id":"P41RR002584","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G6074403036","display_name":"Hypoxia and Radiotherapy: Evaluation and Mitigation in Tumors","funder_award_id":"R01CA139043","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G871178886","display_name":"UT Southwestern Small Animal Imaging Resource","funder_award_id":"U24CA126608","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000898154","display_name":"UT Southwestern Medical Center Simmons Comprehensive Cancer Center","funder_award_id":"P30CA142543","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W119541022","https://openalex.org/W139714128","https://openalex.org/W1508029344","https://openalex.org/W1509715201","https://openalex.org/W1553997414","https://openalex.org/W1618154271","https://openalex.org/W1914698901","https://openalex.org/W1938513152","https://openalex.org/W1952813995","https://openalex.org/W1971345530","https://openalex.org/W1980086703","https://openalex.org/W1982513335","https://openalex.org/W1982845574","https://openalex.org/W1982912299","https://openalex.org/W1987138237","https://openalex.org/W1993669492","https://openalex.org/W1995544868","https://openalex.org/W2011766836","https://openalex.org/W2011810742","https://openalex.org/W2042855386","https://openalex.org/W2044245267","https://openalex.org/W2047603641","https://openalex.org/W2051636979","https://openalex.org/W2061050659","https://openalex.org/W2061277132","https://openalex.org/W2062442976","https://openalex.org/W2070538834","https://openalex.org/W2092371916","https://openalex.org/W2093623701","https://openalex.org/W2094146747","https://openalex.org/W2099461723","https://openalex.org/W2104898472","https://openalex.org/W2106935230","https://openalex.org/W2113664880","https://openalex.org/W2116263694","https://openalex.org/W2119846994","https://openalex.org/W2122771536","https://openalex.org/W2124496728","https://openalex.org/W2132690269","https://openalex.org/W2152749459","https://openalex.org/W2153209580","https://openalex.org/W2155105887","https://openalex.org/W2155491387","https://openalex.org/W2158106343","https://openalex.org/W2183741069","https://openalex.org/W2194245060","https://openalex.org/W2253530324","https://openalex.org/W2315721504","https://openalex.org/W2345464744","https://openalex.org/W2407715263","https://openalex.org/W2413175974","https://openalex.org/W2417841720","https://openalex.org/W2580568552","https://openalex.org/W2600703888","https://openalex.org/W2747259859","https://openalex.org/W2761502029","https://openalex.org/W2800858099","https://openalex.org/W2889082134","https://openalex.org/W2997194916","https://openalex.org/W3141585456"],"related_works":["https://openalex.org/W85841632","https://openalex.org/W2146308184","https://openalex.org/W7039659853","https://openalex.org/W3115686378","https://openalex.org/W2042855386","https://openalex.org/W2061111550","https://openalex.org/W2588193856","https://openalex.org/W2528754718","https://openalex.org/W2144808497","https://openalex.org/W2012390829"],"abstract_inverted_index":{"F]FMISO.":[0],"Correlations":[1],"were":[2,42],"observed":[3,43],"for":[4],"whole":[5],"tumor":[6,20,53],"as":[7,75],"well":[8,18],"on":[9,48],"a":[10,60,86],"regional":[11,70],"basis":[12],"with":[13,34],"stronger":[14],"correlations":[15,33,41,94],"in":[16,59,104],"the":[17,23,66,83,105,109],"perfused":[19,27],"periphery":[21],"indicating":[22,108],"strong":[24],"influence":[25],"of":[26,52,62,68,80,89,112],"vasculature.":[28],"After":[29],"90":[30],"minutes":[31],"most":[32],"signal":[35],"intensity":[36],"became":[37],"quite":[38],"weak,":[39],"but":[40],"between":[44,95],"hypoxic":[45],"fraction":[46],"based":[47],"FMISO":[49],"and":[50,72,99],"fractions":[51],"showing":[54],"BOLD":[55],"or":[56],"TOLD":[57],"response":[58],"subset":[61],"tumors.":[63],"This":[64],"emphasizes":[65],"importance":[67],"considering":[69],"heterogeneity":[71],"responsive":[73],"fractions,":[74],"opposed":[76],"to":[77],"simple":[78],"magnitudes":[79],"responses.":[81],"Although":[82],"data":[84],"represent":[85],"small":[87],"cohort":[88],"tumors":[90],"they":[91],"present":[92],"direct":[93],"oxygen":[96],"sensitive":[97],"MRI":[98],"PET":[100],"hypoxia":[101],"reporter":[102],"agents":[103],"same":[106],"tumors,":[107],"potential":[110],"utility":[111],"further":[113],"investigations.":[114]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":4}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2019-12-05T00:00:00"}
