{"id":"https://openalex.org/W2990631332","doi":"https://doi.org/10.1289/isee.2014.o-030","title":"Ambient and Controlled Particle Exposures as Triggers for Acute ECG-Changes over the Next Few Hours","display_name":"Ambient and Controlled Particle Exposures as Triggers for Acute ECG-Changes over the Next Few Hours","publication_year":2014,"publication_date":"2014-10-20","ids":{"openalex":"https://openalex.org/W2990631332","doi":"https://doi.org/10.1289/isee.2014.o-030","mag":"2990631332"},"language":"en","primary_location":{"id":"doi:10.1289/isee.2014.o-030","doi":"https://doi.org/10.1289/isee.2014.o-030","is_oa":false,"landing_page_url":"https://doi.org/10.1289/isee.2014.o-030","pdf_url":null,"source":{"id":"https://openalex.org/S4210195765","display_name":"ISEE Conference Abstracts","issn_l":"1078-0475","issn":["1078-0475","2169-2181"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISEE Conference Abstracts","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113968343","display_name":"David Q. Rich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Q. Rich*","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088727034","display_name":"Annette Peters","orcid":"https://orcid.org/0000-0001-6645-0985","observed_orcids":["https://orcid.org/0000-0001-6645-0985","https://orcid.org/0000-0003-0984-2258","https://orcid.org/0000-0002-4623-3614"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Annette Peters","raw_affiliation_strings":["2. Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Germany,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2. Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Germany,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002121570","display_name":"Wojciech Zar\u0119ba","orcid":"https://orcid.org/0000-0003-4146-420X","observed_orcids":["https://orcid.org/0000-0003-4146-420X"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wojciech Zareba","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052113711","display_name":"Susanne Breitner","orcid":"https://orcid.org/0000-0002-0956-6911","observed_orcids":["https://orcid.org/0000-0002-0956-6911"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Susanne Breitner","raw_affiliation_strings":["Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060237610","display_name":"Jelani Wiltshire","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jelani Wiltshire","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024093542","display_name":"Mark W. Frampton","orcid":"https://orcid.org/0000-0002-6002-2119","observed_orcids":["https://orcid.org/0000-0002-6002-2119"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Frampton","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062800035","display_name":"Cathleen P. Kane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cathleen Kane","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108662433","display_name":"David Oakes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Oakes","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038157814","display_name":"Mark J. Utell","orcid":"https://orcid.org/0000-0002-4287-0384","observed_orcids":["https://orcid.org/0000-0002-4287-0384"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Utell","raw_affiliation_strings":["University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester School of Medicine and Dentistry, United States,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082234819","display_name":"Alexandra Elisabeth Schneider","orcid":"https://orcid.org/0000-0002-1084-2442","observed_orcids":["https://orcid.org/0000-0002-1084-2442"]},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Munich","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexandra Schneider","raw_affiliation_strings":["Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Germany,  E-mail Address: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Helmholtz Zentrum M\u00fcnchen - German Research Center for Environmental Health, Germany,  E-mail Address: [email\u00a0protected]","institution_ids":["https://openalex.org/I3018134672"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2014","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11002","display_name":"Indoor Air Quality and Microbial Exposure","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/particulate-matter","display_name":"particulate matter","score":0.7599999904632568},{"id":"https://openalex.org/keywords/ultrafine-particles","display_name":"ultrafine particles","score":0.9829999804496765},{"id":"https://openalex.org/keywords/pm2-5","display_name":"PM2.5","score":0.9879999756813049},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":0.9480000138282776},{"id":"https://openalex.org/keywords/sdnn","display_name":"SDNN","score":0.8420000076293945},{"id":"https://openalex.org/keywords/rmssd","display_name":"RMSSD","score":0.9980000257492065},{"id":"https://openalex.org/keywords/acute-cardiovascular-effects","display_name":"acute cardiovascular effects","score":0.6290000081062317},{"id":"https://openalex.org/keywords/air-pollution-exposure","display_name":"air pollution exposure","score":0.6190000176429749},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.6439999938011169},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cardiac-rehabilitation","display_name":"cardiac rehabilitation","score":0.7860000133514404},{"id":"https://openalex.org/keywords/panel-study","display_name":"panel survey","score":0.6129999756813049},{"id":"https://openalex.org/keywords/traffic-related-air-pollution","display_name":"traffic-related air pollution","score":0.6169999837875366},{"id":"https://openalex.org/keywords/electrocardiographic-changes","display_name":"electrocardiographic changes","score":0.5490000247955322},{"id":"https://openalex.org/keywords/replication-study","display_name":"replication study","score":0.5329999923706055},{"id":"https://openalex.org/keywords/augsburg","display_name":"Augsburg","score":0.7260000109672546},{"id":"https://openalex.org/keywords/rochester-new-york","display_name":"Rochester, New York","score":0.9430000185966492}],"concepts":[{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.7434889674186707},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6416497826576233},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.5702705383300781},{"id":"https://openalex.org/C150032891","wikidata":"https://www.wikidata.org/wiki/Q7880535","display_name":"Ultrafine particle","level":2,"score":0.5568422675132751},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4609464108943939},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3946276009082794},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.2614522874355316},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.15910124778747559},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1289/isee.2014.o-030","doi":"https://doi.org/10.1289/isee.2014.o-030","is_oa":false,"landing_page_url":"https://doi.org/10.1289/isee.2014.o-030","pdf_url":null,"source":{"id":"https://openalex.org/S4210195765","display_name":"ISEE Conference Abstracts","issn_l":"1078-0475","issn":["1078-0475","2169-2181"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319799","host_organization_name":"National Institute of Environmental Health Sciences","host_organization_lineage":["https://openalex.org/P4310319799","https://openalex.org/P4310316754"],"host_organization_lineage_names":["National Institute of Environmental Health Sciences","National Institutes of Health"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISEE Conference Abstracts","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2919215848","https://openalex.org/W6939704913","https://openalex.org/W2987161734","https://openalex.org/W4417184589","https://openalex.org/W2168025150","https://openalex.org/W4296893880","https://openalex.org/W2003433943","https://openalex.org/W3164743684","https://openalex.org/W2164646920","https://openalex.org/W1593575057"],"abstract_inverted_index":{"BACKGROUND.":[0],"Few":[1],"studies":[2,47,226],"have":[3],"examined":[4],"whether":[5,25],"short":[6],"term":[7],"increases":[8,116],"in":[9,48,80,117,155,174,221,232,266,279],"particulate":[10],"matter":[11],"concentrations":[12,31,65,122,178],"(within":[13],"a":[14,75,98,272],"few":[15,273],"hours)":[16,79],"impact":[17],"measures":[18],"of":[19,32,77,167,242,249,285],"heart":[20,268],"rate":[21,269],"variability":[22,270],"(HRV),":[23],"and":[24,29,44,51,63,82,94,100,119,144,159,176,201,251],"both":[26],"controlled":[27,45,224],"exposures":[28],"ambient":[30,60],"particles":[33],"lead":[34],"to":[35,59,74,104],"similar":[36],"health":[37],"effects.":[38],"METHODS.":[39],"Using":[40],"data":[41],"from":[42],"panel":[43,102,111,166],"exposure":[46,58,225,260,292],"Augsburg,":[49],"Germany":[50],"Rochester,":[52],"New":[53],"York,":[54],"we":[55,229],"hypothesized":[56],"that":[57,258],"ultrafine":[61],"(UFP)":[62],"PM2.5":[64,121,136,177,192,212],"were":[66,123,179],"associated":[67,124,180,234,262,289],"with":[68,125,157,181,235,263,290],"immediate":[69],"changes":[70],"(concurrent":[71],"hour":[72],"up":[73],"delay":[76],"6":[78],"SDNN":[81,127,183,233,255],"RMSSD.":[83,239],"We":[84],"used":[85],"linear":[86],"mixed":[87],"models,":[88],"adjusting":[89],"for":[90],"time":[91],"trends,":[92],"temperature,":[93],"relative":[95],"humidity,":[96],"applying":[97],"discovery":[99,110],"replication":[101,165],"approach":[103],"make":[105],"inference.":[106],"RESULTS.":[107],"In":[108,163],"the":[109,164,243,282],"(Augsburg),":[112],"interquartile":[113],"range":[114],"(IQR)":[115],"UFP":[118,175,250],"fine":[120,252],"decreased":[126,145,182,202],"(UFP":[128,184,204],"lag":[129,137,185,193,205,213],"1:":[130,138],"-2.1%;":[131,195],"95%":[132,140,151,188,196,208,216],"CI=":[133,141,152,189,209,217],"-3.7%,":[134],"-0.6%;":[135],"-4.6%;":[139],"-7.4%,":[142],"-1.8%),":[143],"RMSSD":[146,203],"(PM2.5":[147],"concurrent":[148],"hour:":[149],"-7.2%;":[150],"-12.1%,":[153],"-2.0%)":[154],"individuals":[156],"diabetes":[158],"impaired":[160],"glucose":[161],"tolerance.":[162],"cardiac":[168],"rehabilitation":[169],"patients":[170],"(Rochester":[171],"panel),":[172],"IQR-increases":[173],"0:":[186],"-1.2%;":[187],"-2.2%,":[190],"-0.1%;":[191],"4:":[194,214],"C":[197],"=":[198],"-3.9%,":[199],"-0.4%),":[200],"3:":[206],"-2.5%;":[207],"-4.0%,":[210],"-1.0%;":[211],"-3.5%;":[215],"-6.1%,":[218],"-0.8%).":[219],"However,":[220],"two":[222],"Rochester":[223],"(replication":[227],"panels),":[228],"observed":[230],"decreases":[231],"UFP,":[236],"but":[237],"not":[238],"CONCLUSIONS:":[240],"Regardless":[241],"underlying":[244],"lag-structure,":[245],"these":[246],"consistent":[247],"effects":[248],"PM":[253,259],"on":[254],"provide":[256],"evidence":[257],"is":[261],"rapid":[264],"decrements":[265],"overall":[267],"within":[271],"hours":[274],"or":[275],"less.":[276],"This":[277],"may,":[278],"part,":[280],"explain":[281],"increased":[283],"risk":[284],"acute":[286],"CV":[287],"events":[288],"traffic":[291],"reported":[293],"previously.":[294]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2019-12-05T00:00:00"}
