{"id":"https://openalex.org/W2990578752","doi":"https://doi.org/10.15407/pp2018.02.280","title":"Specialised computer simulator \"SimEnPhysiol\"","display_name":"Specialised computer simulator \"SimEnPhysiol\"","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2990578752","doi":"https://doi.org/10.15407/pp2018.02.280","mag":"2990578752"},"language":"en","primary_location":{"id":"doi:10.15407/pp2018.02.280","doi":"https://doi.org/10.15407/pp2018.02.280","is_oa":true,"landing_page_url":"https://doi.org/10.15407/pp2018.02.280","pdf_url":"http://pp.isofts.kiev.ua/ojs1/article/download/291/285","source":{"id":"https://openalex.org/S4210223898","display_name":"PROBLEMS IN PROGRAMMING","issn_l":"1727-4907","issn":["1727-4907"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PROBLEMS IN PROGRAMMING","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://pp.isofts.kiev.ua/ojs1/article/download/291/285","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082082219","display_name":"Rafik D. Grygoryan","orcid":"https://orcid.org/0000-0001-8762-733X","observed_orcids":["https://orcid.org/0000-0001-8762-733X"]},"institutions":[{"id":"https://openalex.org/I4210113851","display_name":"Institute of Software Systems","ror":"https://ror.org/0258a2f50","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210113851"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"R.D. Grygoryan","raw_affiliation_strings":["Institute of Software Systems NAS of Ukraine"],"raw_orcid":"https://orcid.org/0000-0001-8762-733X","affiliations":[{"raw_affiliation_string":"Institute of Software Systems NAS of Ukraine","institution_ids":["https://openalex.org/I4210113851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108275067","display_name":"T.V. Aksenova","orcid":"https://orcid.org/0000-0001-5046-2375","observed_orcids":["https://orcid.org/0000-0001-5046-2375"]},"institutions":[{"id":"https://openalex.org/I4210113851","display_name":"Institute of Software Systems","ror":"https://ror.org/0258a2f50","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210113851"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"T.V. Aksonova","raw_affiliation_strings":["Institute of Software Systems NAS of Ukraine"],"raw_orcid":"https://orcid.org/0000-0001-5046-2375","affiliations":[{"raw_affiliation_string":"Institute of Software Systems NAS of Ukraine","institution_ids":["https://openalex.org/I4210113851"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040227425","display_name":"\u0410.G. Degoda","orcid":"https://orcid.org/0000-0001-6364-5568","observed_orcids":["https://orcid.org/0000-0001-6364-5568"]},"institutions":[{"id":"https://openalex.org/I4210113851","display_name":"Institute of Software Systems","ror":"https://ror.org/0258a2f50","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210113851"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"A.G. Degoda","raw_affiliation_strings":["Institute of Software Systems NAS of Ukraine"],"raw_orcid":"https://orcid.org/0000-0001-6364-5568","affiliations":[{"raw_affiliation_string":"Institute of Software Systems NAS of Ukraine","institution_ids":["https://openalex.org/I4210113851"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210113851"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"2-3","first_page":"280","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13286","display_name":"Modeling and Simulation Systems","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13286","display_name":"Modeling and Simulation Systems","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14270","display_name":"Simulation and Modeling Applications","score":0.06019999831914902,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.03799999877810478,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/physiological-simulation","display_name":"physiological simulation","score":0.48500001430511475},{"id":"https://openalex.org/keywords/negative-energy-balance","display_name":"negative energy balance","score":0.5329999923706055},{"id":"https://openalex.org/keywords/atp","display_name":"ATP","score":0.5400000214576721},{"id":"https://openalex.org/keywords/virtual-cell","display_name":"Virtual Cell","score":0.6349999904632568},{"id":"https://openalex.org/keywords/physiological-regulation","display_name":"physiological regulation","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C74318829","wikidata":"https://www.wikidata.org/wiki/Q36458","display_name":"Multicellular organism","level":3,"score":0.6297043561935425},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6017153859138489},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.5403791069984436},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.48683708906173706},{"id":"https://openalex.org/C148699463","wikidata":"https://www.wikidata.org/wiki/Q3492668","display_name":"SSS*","level":2,"score":0.469011515378952},{"id":"https://openalex.org/C186370098","wikidata":"https://www.wikidata.org/wiki/Q442787","display_name":"Energy (signal processing)","level":2,"score":0.4665994644165039},{"id":"https://openalex.org/C2777423268","wikidata":"https://www.wikidata.org/wiki/Q3663116","display_name":"Energy balance","level":2,"score":0.4296698570251465},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4134730100631714},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.23819926381111145},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.22713515162467957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17860627174377441},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.09260234236717224},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.08514541387557983},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.15407/pp2018.02.280","doi":"https://doi.org/10.15407/pp2018.02.280","is_oa":true,"landing_page_url":"https://doi.org/10.15407/pp2018.02.280","pdf_url":"http://pp.isofts.kiev.ua/ojs1/article/download/291/285","source":{"id":"https://openalex.org/S4210223898","display_name":"PROBLEMS IN PROGRAMMING","issn_l":"1727-4907","issn":["1727-4907"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PROBLEMS IN PROGRAMMING","raw_type":"journal-article"},{"id":"pmh:oai:pp.isofts.kiev.ua:article/291","doi":null,"is_oa":true,"landing_page_url":"https://pp.isofts.kiev.ua/index.php/ojs1/article/view/291","pdf_url":"https://pp.isofts.kiev.ua/index.php/ojs1/article/download/291/285","source":{"id":"https://openalex.org/S4210223898","display_name":"PROBLEMS IN PROGRAMMING","issn_l":"1727-4907","issn":["1727-4907"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"10.15407/pp2018.02","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dspace.nbuv.gov.ua:123456789/144639","doi":null,"is_oa":true,"landing_page_url":"http://dspace.nbuv.gov.ua/handle/123456789/144639","pdf_url":"http://dspace.nbuv.gov.ua/handle/123456789/144639","source":{"id":"https://openalex.org/S4306401959","display_name":"The scientific electronic library of periodicals of the National Academy of Sciences of Ukraine (National Academy of Sciences of Ukraine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149851306","host_organization_name":"National Academy of Sciences of Ukraine","host_organization_lineage":["https://openalex.org/I149851306"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:harvester.nas.gov.ua:pp_isofts_kiev_ua-article-291","doi":null,"is_oa":false,"landing_page_url":"https://harvester.nas.gov.ua/Record/pp_isofts_kiev_ua-article-291","pdf_url":null,"source":{"id":"https://openalex.org/S7407055165","display_name":"Open Publication Harvester of National Academy of Sciences of Ukraine","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.15407/pp2018.02.280","doi":"https://doi.org/10.15407/pp2018.02.280","is_oa":true,"landing_page_url":"https://doi.org/10.15407/pp2018.02.280","pdf_url":"http://pp.isofts.kiev.ua/ojs1/article/download/291/285","source":{"id":"https://openalex.org/S4210223898","display_name":"PROBLEMS IN PROGRAMMING","issn_l":"1727-4907","issn":["1727-4907"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PROBLEMS IN PROGRAMMING","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2990578752.pdf","grobid_xml":"https://content.openalex.org/works/W2990578752.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1261199295","https://openalex.org/W1515601487","https://openalex.org/W1964417181","https://openalex.org/W1980103104","https://openalex.org/W1995253129","https://openalex.org/W2112696414","https://openalex.org/W2153795286","https://openalex.org/W2168412919","https://openalex.org/W2626725022","https://openalex.org/W2710553436","https://openalex.org/W2727636249"],"related_works":["https://openalex.org/W7035076992","https://openalex.org/W2710553436","https://openalex.org/W7137560477","https://openalex.org/W2905292869","https://openalex.org/W7218048265","https://openalex.org/W7137742964","https://openalex.org/W160938525","https://openalex.org/W4407845720","https://openalex.org/W7164785771","https://openalex.org/W6997782072"],"abstract_inverted_index":{"A":[0],"specialized":[1],"software":[2,199],"simulator":[3],"(SSS)":[4],"is":[5,25,53,105,143,195,203],"described.":[6],"SSS":[7,24,52,152,194],"simulates":[8],"the":[9,15,45,51,59,62,89,111,113,120,126,132,135,138,161,167,172,177,181,198],"human":[10],"physiological":[11,32,100,122,173],"complex":[12],"reactions":[13],"to":[14,49,67,124,140,155,165],"appearance":[16],"of":[17,39,44,61,93,110,134,137,169,171,186],"energy":[18,40,76,86,117,128,178],"shortages":[19],"(ATP":[20],"molecules)":[21],"in":[22,41,175,180,197,211],"cells.":[23],"based":[26,147],"on":[27,148,160,207],"mathematical":[28],"models,":[29],"representing":[30],"multilevel":[31],"mechanisms":[33,91,101,123,136,142],"that":[34,57,107],"provide":[35],"a":[36,54,79,83,208],"long-term":[37],"balance":[38],"each":[42,170],"cell":[43,63,81,84,114,163],"body.":[46],"The":[47,151,184,191],"key":[48],"creating":[50],"binary":[55],"model":[56],"ignores":[58],"specialization":[60],"and":[64,95,98,164,202],"reduces":[65],"them":[66,72],"two":[68],"virtual":[69,162,182],"cells":[70,94],"differed":[71],"only":[73],"by":[74],"their":[75],"status":[77],"\u2013":[78],"balanced":[80],"or":[82],"experiencing":[85],"deficit.":[87],"Both":[88],"autonomous":[90,204],"(AM)":[92],"multicellular":[96,121],"local":[97],"general":[99],"are":[102,189],"modelled.":[103],"It":[104],"assumed":[106],"under":[108],"incapacity":[109],"AM,":[112],"having":[115],"an":[116],"deficit":[118,179],"activates":[119],"restore":[125],"disturbed":[127],"balance.":[129],"In":[130],"fact,":[131],"help":[133],"organism":[139],"cellular":[141],"provided":[144],"through":[145],"regulators":[146,174],"negative":[149],"feedback.":[150],"allows":[153],"one":[154],"simulate":[156],"every":[157],"dynamic":[158],"load":[159],"evaluate":[166],"contribution":[168],"counteracting":[176],"cell.":[183],"results":[185],"test":[187],"studies":[188],"presented.":[190],"physiologist-researcher":[192],"aimed":[193],"implemented":[196],"technology":[200],"DOT.NET,":[201],"for":[205],"use":[206],"PC.":[209],"Problems":[210],"programming":[212],"2018;":[213],"2-3:":[214],"280-287":[215]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-05T00:00:00"}