{"id":"https://openalex.org/W2990224416","doi":"https://doi.org/10.3390/coatings9120790","title":"The Effects of Atmospheric Pressure Argon Plasma Treated Bovine Bone Substitute on Bone Regeneration","display_name":"The Effects of Atmospheric Pressure Argon Plasma Treated Bovine Bone Substitute on Bone Regeneration","publication_year":2019,"publication_date":"2019-11-25","ids":{"openalex":"https://openalex.org/W2990224416","doi":"https://doi.org/10.3390/coatings9120790","mag":"2990224416"},"language":"en","primary_location":{"id":"doi:10.3390/coatings9120790","doi":"https://doi.org/10.3390/coatings9120790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/coatings9120790","pdf_url":"https://www.mdpi.com/2079-6412/9/12/790/pdf?version=1576551401","source":{"id":"https://openalex.org/S4210205742","display_name":"Coatings","issn_l":"2079-6412","issn":["2079-6412"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coatings","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-6412/9/12/790/pdf?version=1576551401","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031672309","display_name":"Jong-Ju Ahn","orcid":"https://orcid.org/0000-0002-7771-9190","observed_orcids":["https://orcid.org/0000-0002-7771-9190"]},"institutions":[{"id":"https://openalex.org/I4210139927","display_name":"Pusan National University Dental Hospital","ror":"https://ror.org/041baww89","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jong-Ju Ahn","raw_affiliation_strings":["Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083366892","display_name":"Ji-Hyun Yoo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji-Hyun Yoo","raw_affiliation_strings":["Department of Oral Physiology, Dental Research Institute, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Physiology, Dental Research Institute, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066613479","display_name":"Eun\u2010Bin Bae","orcid":"https://orcid.org/0000-0002-9524-3835","observed_orcids":["https://orcid.org/0000-0002-9524-3835"]},"institutions":[{"id":"https://openalex.org/I4210139927","display_name":"Pusan National University Dental Hospital","ror":"https://ror.org/041baww89","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eun-Bin Bae","raw_affiliation_strings":["Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":"https://orcid.org/0000-0002-9524-3835","affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005336250","display_name":"Gyoo\u2010Cheon Kim","orcid":"https://orcid.org/0000-0003-3568-3529","observed_orcids":["https://orcid.org/0000-0003-3568-3529"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Gyoo-Cheon Kim","raw_affiliation_strings":["Department of Oral Anatomy and Cell Biology, School of Dentistry, Pusan National University, Yangsan 50612, Korea","Research & Development Center, FEAGLE Corporation, Yangsan 50614, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Anatomy and Cell Biology, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4921948"]},{"raw_affiliation_string":"Research & Development Center, FEAGLE Corporation, Yangsan 50614, Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034021534","display_name":"Jae Joon Hwang","orcid":"https://orcid.org/0000-0003-0379-8460","observed_orcids":["https://orcid.org/0000-0003-0379-8460"]},"institutions":[{"id":"https://openalex.org/I4210139927","display_name":"Pusan National University Dental Hospital","ror":"https://ror.org/041baww89","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jae Joon Hwang","raw_affiliation_strings":["Department of Oral and Maxillofacial Radiology, School of Dentistry, Pusan National University, Dental Research Institute, Yangsan 50612, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Radiology, School of Dentistry, Pusan National University, Dental Research Institute, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112479197","display_name":"Wan\u2010Sun Lee","orcid":"https://orcid.org/0000-0002-4410-5854","observed_orcids":["https://orcid.org/0000-0002-4410-5854"]},"institutions":[{"id":"https://openalex.org/I4210139927","display_name":"Pusan National University Dental Hospital","ror":"https://ror.org/041baww89","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Wan-Sun Lee","raw_affiliation_strings":["Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100744569","display_name":"Hyung Joon Kim","orcid":"https://orcid.org/0000-0002-2962-9553","observed_orcids":["https://orcid.org/0000-0002-2962-9553"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hyung-Joon Kim","raw_affiliation_strings":["Department of Oral Physiology, Dental Research Institute, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Physiology, Dental Research Institute, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084811011","display_name":"Jung\u2010Bo Huh","orcid":"https://orcid.org/0000-0001-7578-1989","observed_orcids":["https://orcid.org/0000-0001-7578-1989"]},"institutions":[{"id":"https://openalex.org/I4210139927","display_name":"Pusan National University Dental Hospital","ror":"https://ror.org/041baww89","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]},{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jung-Bo Huh","raw_affiliation_strings":["Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea"],"raw_orcid":"https://orcid.org/0000-0002-2962-9553","affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Dental Research Institute, Dental and Life Science Institute, BK21 PLUS Project, School of Dentistry, Pusan National University, Yangsan 50612, Korea","institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084811011","https://openalex.org/A5100744569"],"corresponding_institution_ids":["https://openalex.org/I4210139927","https://openalex.org/I4921948"],"apc_list":{"value":1600,"currency":"CHF","value_usd":1621},"apc_paid":{"value":1600,"currency":"CHF","value_usd":1621},"fwci":0.0778,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.3348008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"9","issue":"12","first_page":"790","last_page":"790"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10359","display_name":"Dental Implant Techniques and Outcomes","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xenogeneic-bone-substitute","display_name":"xenogeneic bone substitute","score":0.7260000109672546},{"id":"https://openalex.org/keywords/bone-regeneration","display_name":"bone regeneration","score":0.8899999856948853},{"id":"https://openalex.org/keywords/calvarial-defect","display_name":"calvarial defect","score":0.8500000238418579},{"id":"https://openalex.org/keywords/osteogenic-differentiation","display_name":"osteogenic differentiation","score":0.8989999890327454},{"id":"https://openalex.org/keywords/mineralization","display_name":"mineralization","score":0.9049999713897705},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C3019162307","wikidata":"https://www.wikidata.org/wiki/Q9530","display_name":"Expired air","level":2,"score":0.7566264867782593},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6757392883300781},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5502576231956482},{"id":"https://openalex.org/C2993291840","wikidata":"https://www.wikidata.org/wiki/Q1121544","display_name":"Bone formation","level":2,"score":0.5244331955909729},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5210630297660828},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3461911082267761},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2970573902130127},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27429407835006714},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11496713757514954},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.08913490176200867},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/coatings9120790","doi":"https://doi.org/10.3390/coatings9120790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/coatings9120790","pdf_url":"https://www.mdpi.com/2079-6412/9/12/790/pdf?version=1576551401","source":{"id":"https://openalex.org/S4210205742","display_name":"Coatings","issn_l":"2079-6412","issn":["2079-6412"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coatings","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/coatings9120790","doi":"https://doi.org/10.3390/coatings9120790","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/coatings9120790","pdf_url":"https://www.mdpi.com/2079-6412/9/12/790/pdf?version=1576551401","source":{"id":"https://openalex.org/S4210205742","display_name":"Coatings","issn_l":"2079-6412","issn":["2079-6412"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Coatings","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2990224416.pdf","grobid_xml":"https://content.openalex.org/works/W2990224416.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W146671891","https://openalex.org/W1417840079","https://openalex.org/W1600024584","https://openalex.org/W1716919355","https://openalex.org/W1972557410","https://openalex.org/W1975451456","https://openalex.org/W1977956953","https://openalex.org/W1995143529","https://openalex.org/W2007329550","https://openalex.org/W2007929121","https://openalex.org/W2012079711","https://openalex.org/W2017103564","https://openalex.org/W2028251796","https://openalex.org/W2034794242","https://openalex.org/W2044194804","https://openalex.org/W2052284195","https://openalex.org/W2057618822","https://openalex.org/W2058948421","https://openalex.org/W2059567868","https://openalex.org/W2064443286","https://openalex.org/W2070614648","https://openalex.org/W2078441252","https://openalex.org/W2079352528","https://openalex.org/W2083878294","https://openalex.org/W2100360262","https://openalex.org/W2110027504","https://openalex.org/W2125685916","https://openalex.org/W2128788864","https://openalex.org/W2135228968","https://openalex.org/W2164823732","https://openalex.org/W2171176742","https://openalex.org/W2199338994","https://openalex.org/W2470905682","https://openalex.org/W2499587366","https://openalex.org/W2573556537","https://openalex.org/W2791619823","https://openalex.org/W2800812169","https://openalex.org/W2803368633","https://openalex.org/W2886612354","https://openalex.org/W2898473495","https://openalex.org/W2899754560","https://openalex.org/W2912136263","https://openalex.org/W2954788687","https://openalex.org/W2973289391","https://openalex.org/W4205239344","https://openalex.org/W6628299986"],"related_works":["https://openalex.org/W2070614648","https://openalex.org/W3159790524","https://openalex.org/W2800812169","https://openalex.org/W7144824290","https://openalex.org/W3193530689","https://openalex.org/W2989849908","https://openalex.org/W3045778732","https://openalex.org/W4414451590","https://openalex.org/W3094089847","https://openalex.org/W3186085024"],"abstract_inverted_index":{"This":[0],"study":[1,158],"was":[2,103,149,187],"undertaken":[3],"to":[4,21,203],"compare":[5],"new":[6],"bone":[7,15,35,98,183,192,205],"formation":[8],"between":[9,153,195],"non-expired":[10],"and":[11,20,58,70,85,117,121,132,135],"expired":[12,34,56,66],"bovine-derived":[13],"xenogeneic":[14],"substitute":[16,36,99],"(expired,":[17],"out-of-use":[18],"period)":[19],"evaluate":[22],"the":[23,86,92,95,106,113,118,127,156,163,168,179,212],"efficacy":[24],"of":[25,94,100,129,165,171,182],"argon":[26],"(Ar)-based":[27],"atmospheric":[28],"pressure":[29],"plasma":[30],"(APP)":[31],"treatment":[32,170],"on":[33,91,178,201],"in":[37,75,82,155,191,197,211],"rat":[38],"calvarial":[39],"defect.":[40],"The":[41,97],"groups":[42,137,154,196],"were":[43,73,79,89,115,124,138],"divided":[44],"into":[45,105],"(1)":[46],"Non/Expired":[47,134],"group":[48,54,61,102,143],"(Using":[49,55,62],"regular":[50],"xenografts),":[51,57],"(2)":[52],"Expired":[53,142],"(3)":[59],"Ar/Expired":[60,136],"Ar-based":[63,172],"APP":[64,173,202],"treated":[65],"xenografts).":[67],"Surface":[68],"observation":[69],"cell":[71],"experiments":[72],"performed":[74],"vitro.":[76],"Twelve":[77],"rats":[78,114],"used":[80],"for":[81],"vivo":[83],"experiment":[84],"bony":[87],"defects":[88],"created":[90],"middle":[93],"cranium.":[96],"each":[101],"implanted":[104],"defective":[107],"site.":[108],"After":[109],"4":[110],"weeks,":[111],"all":[112],"sacrificed,":[116],"volumetric,":[119],"histologic,":[120],"histometric":[122],"analyses":[123],"performed.":[125],"In":[126],"results":[128],"osteogenic":[130],"differentiation":[131],"mineralization,":[133],"significantly":[139],"higher":[140],"than":[141],"(p":[144,159],"<":[145],"0.05).":[146,161],"However,":[147,185],"there":[148,186],"no":[150,188],"significant":[151,189],"difference":[152,190],"animal":[157],">":[160],"Within":[162],"limitations":[164],"this":[166],"study,":[167],"surface":[169,180],"has":[174],"a":[175],"potential":[176],"effect":[177],"modification":[181],"grafts.":[184],"regeneration":[193,206],"ability":[194],"vivo;":[198],"thus,":[199],"studies":[200],"enhance":[204],"should":[207],"be":[208],"carried":[209],"out":[210],"future.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-12-05T00:00:00"}
