{"id":"https://openalex.org/W2990196239","doi":"https://doi.org/10.1111/jcpt.13084","title":"Genetic associations of docetaxel\u2010based chemotherapy\u2010induced myelosuppression in Chinese Han population","display_name":"Genetic associations of docetaxel\u2010based chemotherapy\u2010induced myelosuppression in Chinese Han population","publication_year":2019,"publication_date":"2019-11-28","ids":{"openalex":"https://openalex.org/W2990196239","doi":"https://doi.org/10.1111/jcpt.13084","mag":"2990196239","pmid":"https://pubmed.ncbi.nlm.nih.gov/31778586"},"language":"en","primary_location":{"id":"doi:10.1111/jcpt.13084","doi":"https://doi.org/10.1111/jcpt.13084","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jcpt.13084","pdf_url":null,"source":{"id":"https://openalex.org/S156693432","display_name":"Journal of Clinical Pharmacy and Therapeutics","issn_l":"0269-4727","issn":["0269-4727","1365-2710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pharmacy and Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109259882","display_name":"Weihua Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210125993","display_name":"Luoyang Central Hospital Affiliated to Zhengzhou University","ror":"https://ror.org/03cg5ap92","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210125993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weihua Ren","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","Clinical Laboratory Center, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Clinical Laboratory Center, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China","institution_ids":["https://openalex.org/I4210125993"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chenxi Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenxi Zhou","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026850915","display_name":"Yedong Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yedong Liu","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037708198","display_name":"Keli Su","orcid":"https://orcid.org/0000-0003-4910-978X","observed_orcids":["https://orcid.org/0000-0003-4910-978X"]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keli Su","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100652147","display_name":"Jia Li","orcid":"https://orcid.org/0000-0003-4017-1157","observed_orcids":["https://orcid.org/0000-0003-4017-1157","https://orcid.org/0009-0008-0485-1124"]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Jia","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101977687","display_name":"Luan Chen","orcid":"https://orcid.org/0000-0001-9635-066X","observed_orcids":["https://orcid.org/0000-0001-9635-066X"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Luan Chen","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100361469","display_name":"Mo Li","orcid":"https://orcid.org/0000-0002-9915-1348","observed_orcids":["https://orcid.org/0000-0002-9915-1348"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mo Li","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109462006","display_name":"Jingsong Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingsong Ma","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003115678","display_name":"Wei Zhou","orcid":"https://orcid.org/0000-0001-9636-7963","observed_orcids":["https://orcid.org/0000-0001-9636-7963"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Zhou","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011791931","display_name":"Suli Zhang","orcid":"https://orcid.org/0000-0002-9711-9387","observed_orcids":["https://orcid.org/0000-0002-9711-9387"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Suli Zhang","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","The Fourth People's Hospital of Jinan City Taishan Medical College Jinan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City Taishan Medical College Jinan China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100366416","display_name":"Di Zhang","orcid":"https://orcid.org/0000-0002-9199-5634","observed_orcids":["https://orcid.org/0000-0002-9199-5634","https://orcid.org/0000-0002-9661-7237","https://orcid.org/0000-0003-4551-5393","https://orcid.org/0009-0003-2700-7667"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Zhang","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","Life Science College, Anhui Medical University, Anhui, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Life Science College, Anhui Medical University, Anhui, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060921407","display_name":"Zhiliang Cong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiliang Cong","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032732272","display_name":"Xuecai Niu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuecai Niu","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shengui Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengui Zhang","raw_affiliation_strings":["Bio\u2010X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education) Shanghai Jiao Tong University Shanghai China","The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio\u2010X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education) Shanghai Jiao Tong University Shanghai China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100775693","display_name":"Lu Shen","orcid":"https://orcid.org/0000-0002-0659-2399","observed_orcids":["https://orcid.org/0000-0002-0659-2399"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu Shen","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102026730","display_name":"Cong Huai","orcid":"https://orcid.org/0000-0002-5946-3179","observed_orcids":["https://orcid.org/0000-0002-5946-3179"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cong Huai","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100765624","display_name":"Xiaofang Sun","orcid":"https://orcid.org/0000-0002-3308-5325","observed_orcids":["https://orcid.org/0000-0002-3308-5325"]},"institutions":[{"id":"https://openalex.org/I4210092091","display_name":"Third Affiliated Hospital of Guangzhou Medical University","ror":"https://ror.org/00fb35g87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210092091"]},{"id":"https://openalex.org/I92039509","display_name":"Guangzhou Medical University","ror":"https://ror.org/00zat6v61","country_code":"CN","type":"education","lineage":["https://openalex.org/I92039509"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofang Sun","raw_affiliation_strings":["The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210092091","https://openalex.org/I92039509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101920964","display_name":"Guorong Li","orcid":"https://orcid.org/0000-0002-9439-4754","observed_orcids":["https://orcid.org/0000-0002-9439-4754"]},"institutions":[{"id":"https://openalex.org/I28006308","display_name":"Shandong Normal University","ror":"https://ror.org/01wy3h363","country_code":"CN","type":"education","lineage":["https://openalex.org/I28006308"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guorong Li","raw_affiliation_strings":["Shandong Normal University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Normal University, Jinan, China","institution_ids":["https://openalex.org/I28006308"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030829801","display_name":"Shengying Qin","orcid":"https://orcid.org/0000-0002-8458-5960","observed_orcids":["https://orcid.org/0000-0002-8458-5960"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210092091","display_name":"Third Affiliated Hospital of Guangzhou Medical University","ror":"https://ror.org/00fb35g87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210092091"]},{"id":"https://openalex.org/I92039509","display_name":"Guangzhou Medical University","ror":"https://ror.org/00zat6v61","country_code":"CN","type":"education","lineage":["https://openalex.org/I92039509"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shengying Qin","raw_affiliation_strings":["Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-8458-5960","affiliations":[{"raw_affiliation_string":"Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I4210092091","https://openalex.org/I92039509"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101662583","display_name":"Liang Guo","orcid":"https://orcid.org/0000-0002-8748-5770","observed_orcids":["https://orcid.org/0000-0002-8748-5770","https://orcid.org/0000-0002-1085-8903","https://orcid.org/0009-0005-6166-3603"]},"institutions":[{"id":"https://openalex.org/I4210099937","display_name":"Fourth People\u2019s Hospital of Jinan","ror":"https://ror.org/012xbj452","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099937"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liang Guo","raw_affiliation_strings":["The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Fourth People's Hospital of Jinan City, Taishan Medical College, Jinan, China","institution_ids":["https://openalex.org/I4210099937"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5030829801","https://openalex.org/A5101662583"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210092091","https://openalex.org/I4210099937","https://openalex.org/I92039509"],"apc_list":{"value":3100,"currency":"USD","value_usd":3100},"apc_paid":null,"fwci":1.7577,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.83526159,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"45","issue":"2","first_page":"354","last_page":"364"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/docetaxel","display_name":"docetaxel","score":0.9919999837875366},{"id":"https://openalex.org/keywords/chemotherapy-induced-myelosuppression","display_name":"chemotherapy-induced myelosuppression","score":0.9190000295639038},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7020000219345093},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9769999980926514},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.8149999976158142},{"id":"https://openalex.org/keywords/han-chinese","display_name":"Han Chinese","score":0.8479999899864197},{"id":"https://openalex.org/keywords/pept1","display_name":"PepT1","score":0.8820000290870667},{"id":"https://openalex.org/keywords/pregnane-x-receptor","display_name":"pregnane X receptor","score":0.949999988079071},{"id":"https://openalex.org/keywords/fmo3","display_name":"FMO3","score":0.9980000257492065},{"id":"https://openalex.org/keywords/drug-transporters","display_name":"drug transporters","score":0.7059999704360962},{"id":"https://openalex.org/keywords/drug-metabolizing-enzymes","display_name":"drug-metabolizing enzymes","score":0.777999997138977},{"id":"https://openalex.org/keywords/gene-gene-interaction","display_name":"gene-gene interaction","score":0.7940000295639038},{"id":"https://openalex.org/keywords/personalized-chemotherapy","display_name":"personalized chemotherapy","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C2781190966","wikidata":"https://www.wikidata.org/wiki/Q420436","display_name":"Docetaxel","level":3,"score":0.8726806044578552},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8414808511734009},{"id":"https://openalex.org/C25249476","wikidata":"https://www.wikidata.org/wiki/Q6934678","display_name":"Multifactor dimensionality reduction","level":5,"score":0.7585210800170898},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6671760082244873},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.6412615776062012},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6290897130966187},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.4196354150772095},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4091919958591461},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.37107253074645996},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.36476054787635803},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2042103111743927},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16163310408592224},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09556823968887329}],"mesh":[{"descriptor_ui":"D000077143","descriptor_name":"Docetaxel","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000077143","descriptor_name":"Docetaxel","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/jcpt.13084","doi":"https://doi.org/10.1111/jcpt.13084","is_oa":false,"landing_page_url":"https://doi.org/10.1111/jcpt.13084","pdf_url":null,"source":{"id":"https://openalex.org/S156693432","display_name":"Journal of Clinical Pharmacy and Therapeutics","issn_l":"0269-4727","issn":["0269-4727","1365-2710"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Pharmacy and Therapeutics","raw_type":"journal-article"},{"id":"pmid:31778586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31778586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical pharmacy and therapeutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G113104360","display_name":null,"funder_award_id":"2016YFC120020 0","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G1905207532","display_name":null,"funder_award_id":"2016YFC0905000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G2906869900","display_name":"\u4e2d\u56fd\u4eba\u7fa4\u5229\u57f9\u916e\u836f\u6548\u76f8\u5173\u591a\u6001\u6027\u6807\u8bb0\u7684\u7cfb\u7edf\u6027\u7814\u7a76\u53ca\u5176\u68c0\u6d4b\u82af\u7247\u7684\u7814\u5236","funder_award_id":"30900799","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4173069720","display_name":null,"funder_award_id":"81273596","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5026246862","display_name":null,"funder_award_id":"13DZ2260500","funder_id":"https://openalex.org/F6602968322","funder_display_name":"Shanghai Key Laboratory of Psychotic Disorders"},{"id":"https://openalex.org/G563371026","display_name":null,"funder_award_id":"2012AA02A515","funder_id":"https://openalex.org/F4320335773","funder_display_name":"National High-tech Research and Development Program"},{"id":"https://openalex.org/G574439682","display_name":null,"funder_award_id":"81,773,818","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5888865255","display_name":null,"funder_award_id":"81671326","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6324177120","display_name":null,"funder_award_id":"2016YFC0906400","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G6432307361","display_name":null,"funder_award_id":"182300410385","funder_id":"https://openalex.org/F4320323845","funder_display_name":"Natural Science Foundation of Henan Province"},{"id":"https://openalex.org/G7050415737","display_name":null,"funder_award_id":"2012AA021802","funder_id":"https://openalex.org/F4320335773","funder_display_name":"National High-tech Research and Development Program"},{"id":"https://openalex.org/G8453613630","display_name":null,"funder_award_id":"2016YFC0905002","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323845","display_name":"Natural Science Foundation of Henan Province","ror":null},{"id":"https://openalex.org/F4320335773","display_name":"National High-tech Research and Development Program","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F6602968322","display_name":"Shanghai Key Laboratory of Psychotic Disorders","ror":"https://ror.org/03v7fwy38"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1525132786","https://openalex.org/W1545401674","https://openalex.org/W1667162022","https://openalex.org/W1849903145","https://openalex.org/W1935757694","https://openalex.org/W1968812281","https://openalex.org/W1984820569","https://openalex.org/W1986462580","https://openalex.org/W1989618497","https://openalex.org/W1991940477","https://openalex.org/W1992237854","https://openalex.org/W1996323553","https://openalex.org/W2000478673","https://openalex.org/W2009330784","https://openalex.org/W2009461889","https://openalex.org/W2034521424","https://openalex.org/W2045206092","https://openalex.org/W2047673200","https://openalex.org/W2052140659","https://openalex.org/W2063469571","https://openalex.org/W2064840777","https://openalex.org/W2070774470","https://openalex.org/W2083336892","https://openalex.org/W2083356003","https://openalex.org/W2084166179","https://openalex.org/W2085223528","https://openalex.org/W2089579716","https://openalex.org/W2095353714","https://openalex.org/W2097221602","https://openalex.org/W2106341748","https://openalex.org/W2107028900","https://openalex.org/W2125687910","https://openalex.org/W2126871433","https://openalex.org/W2129949847","https://openalex.org/W2145238269","https://openalex.org/W2152332945","https://openalex.org/W2154067964","https://openalex.org/W2161633633","https://openalex.org/W2164705071","https://openalex.org/W2173055827","https://openalex.org/W2323860656","https://openalex.org/W2415602004","https://openalex.org/W2605816708","https://openalex.org/W2746768441","https://openalex.org/W2888640327","https://openalex.org/W4298026321","https://openalex.org/W4322696731","https://openalex.org/W6675788183","https://openalex.org/W7073795171"],"related_works":["https://openalex.org/W2313770006","https://openalex.org/W2091554302","https://openalex.org/W2505771910","https://openalex.org/W2131443715","https://openalex.org/W6982005962","https://openalex.org/W1991940477","https://openalex.org/W1511083269","https://openalex.org/W2249392395","https://openalex.org/W1503260903","https://openalex.org/W2047673200"],"abstract_inverted_index":{"WHAT":[0,205],"IS":[1,206],"KNOWN":[2],"AND":[3,149,208],"OBJECTIVE:":[4],"Myelosuppression,":[5],"an":[6,187],"adverse":[7],"drug":[8,103],"reaction":[9],"(ADR),":[10],"often":[11],"causes":[12],"medical":[13],"treatment":[14],"termination":[15],"in":[16,45,52,88,97,113,157,231],"cancer":[17],"patients.":[18,73,91,243],"It":[19],"has":[20],"been":[21],"known":[22],"that":[23,100,154,178],"genetic":[24,48],"components,":[25],"such":[26],"as":[27],"single-nucleotide":[28],"polymorphisms":[29],"(SNPs),":[30],"influence":[31],"the":[32,37,60,125],"risk":[33],"of":[34,47,82,191,217,236],"myelosuppression":[35,69,87,193],"at":[36],"individual-patient":[38],"level.":[39],"However,":[40],"due":[41],"to":[42,59,240],"ethnic":[43],"variation":[44],"frequency":[46],"polymorphisms,":[49],"results":[50,152],"reported":[51],"Caucasian":[53],"patients":[54,117],"may":[55],"not":[56],"be":[57],"generalizable":[58],"Chinese":[61,71,90,115,241],"Han":[62,72,89,116,242],"population.":[63],"Until":[64],"now,":[65],"few":[66],"researches":[67],"on":[68],"included":[70],"In":[74],"this":[75],"study,":[76],"we":[77],"conducted":[78,123],"a":[79,179],"systematic":[80],"study":[81],"potential":[83],"biomarkers":[84,216],"for":[85,102],"docetaxel-induced":[86,173,192,218],"METHODS:":[92],"We":[93],"examined":[94],"61":[95],"SNPs":[96,130,156],"36":[98],"genes":[99,159],"code":[101],"transporters,":[104],"metabolism":[105],"enzymes,":[106],"nuclear":[107],"receptors":[108],"and":[109,136,168,224],"DNA":[110],"repair":[111],"pathway":[112],"110":[114],"receiving":[118],"docetaxel-based":[119,237],"chemotherapy.":[120],"Genotyping":[121],"was":[122,186],"using":[124],"Sequenom":[126],"MassARRAY":[127],"system.":[128],"Significant":[129],"were":[131,139,170],"identified":[132],"by":[133,141],"logistic":[134],"regression,":[135],"gene-gene":[137],"interactions":[138],"investigated":[140],"generalized":[142],"multifactor":[143],"dimensionality":[144],"reduction":[145],"(GMDR)":[146],"analysis.":[147],"RESULTS":[148],"DISCUSSION:":[150],"Our":[151,210],"revealed":[153],"11":[155],"nine":[158],"(SLC15A1,":[160],"SLCO1A2,":[161],"CYP2D6,":[162],"FMO3,":[163],"UGT1A1,":[164],"NAT2,":[165],"SULT2A1,":[166],"PXR":[167,222],"HNF4\u03b1)":[169],"associated":[171],"with":[172],"myelosuppression.":[174],"GMDR":[175],"analyses":[176],"suggested":[177],"3-locus":[180],"model:":[181],"SLC15A1":[182,220],"rs2297322-PXR":[183],"rs3732359-FMO3":[184],"rs2266782":[185],"appropriate":[188],"predictive":[189,215],"model":[190],"(P":[194],"=":[195,199,203],".017,":[196],"Testing":[197],"Bal.Acc":[198],"0.653,":[200],"CV":[201],"Consistency":[202],"10/10).":[204],"NEW":[207],"CONCLUSION:":[209],"findings":[211],"suggest":[212],"multiple":[213],"novel":[214],"myelosuppression:":[219],"rs2297322,":[221],"rs3732359":[223],"FMO3":[225],"rs2266782.":[226],"These":[227],"discoveries":[228],"should":[229],"help":[230],"advancing":[232],"future":[233],"personalized":[234],"therapy":[235],"chemotherapy":[238],"specific":[239]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-12-05T00:00:00"}