{"id":"https://openalex.org/W2990195982","doi":null,"title":"CATCH-KB: Establishing a Pharmacogenomics Variant Repository for Chemotherapy-Induced Cardiotoxicity.","display_name":"CATCH-KB: Establishing a Pharmacogenomics Variant Repository for Chemotherapy-Induced Cardiotoxicity.","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2990195982","mag":"2990195982","pmid":"https://pubmed.ncbi.nlm.nih.gov/29888066","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:4944162","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060074314","display_name":"Maggie Morash","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maggie Morash","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104197959","display_name":"Hannah Mitchell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hannah Mitchell","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048519689","display_name":"Anthony Francis Yu","orcid":"https://orcid.org/0000-0002-7120-8285","observed_orcids":["https://orcid.org/0000-0002-7120-8285"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony Yu","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059954337","display_name":"Thomas R. Campion","orcid":"https://orcid.org/0000-0001-7624-769X","observed_orcids":["https://orcid.org/0000-0001-7624-769X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Campion","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047882814","display_name":"Himisha Beltran","orcid":"https://orcid.org/0000-0003-3259-2226","observed_orcids":["https://orcid.org/0000-0003-3259-2226"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Himisha Beltran","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061702711","display_name":"Olivier Elemento","orcid":"https://orcid.org/0000-0002-8061-9617","observed_orcids":["https://orcid.org/0000-0002-8061-9617"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivier Elemento","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051691741","display_name":"Jyotishman Pathak","orcid":"https://orcid.org/0000-0002-4856-410X","observed_orcids":["https://orcid.org/0000-0002-4856-410X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jyotishman Pathak","raw_affiliation_strings":["Weill Cornell Medicine, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Cornell Medicine, New York, USA","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3785,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.68308217,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"2017","issue":null,"first_page":"168","last_page":"177"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.8690999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11535","display_name":"Chemotherapy-induced cardiotoxicity and mitigation","score":0.8690999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.048500001430511475,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemotherapy-induced-cardiotoxicity","display_name":"chemotherapy-induced cardiotoxicity","score":0.968999981880188},{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.996999979019165},{"id":"https://openalex.org/keywords/genetic-variants","display_name":"genetic variants","score":0.8960000276565552},{"id":"https://openalex.org/keywords/gene-disease-association","display_name":"gene-disease association","score":0.5879999995231628},{"id":"https://openalex.org/keywords/genetic-screening","display_name":"genetic screening","score":0.8759999871253967},{"id":"https://openalex.org/keywords/cardiotoxicity-prevention","display_name":"cardiotoxicity prevention","score":0.7590000033378601},{"id":"https://openalex.org/keywords/knowledge-base","display_name":"knowledge base","score":0.36500000953674316}],"concepts":[{"id":"https://openalex.org/C170734499","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenomics","level":2,"score":0.8514721393585205},{"id":"https://openalex.org/C2778233292","wikidata":"https://www.wikidata.org/wiki/Q2118956","display_name":"Cardiotoxicity","level":3,"score":0.7937072515487671},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.4452225863933563},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42128443717956543},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4164888262748718},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3813592791557312},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3796103894710541},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30643603205680847},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.294411838054657},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2815782427787781},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19775745272636414},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.08679196238517761}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:4944162","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5961780","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Jt Summits Transl Sci Proc","raw_type":"Text"},{"id":"pmid:29888066","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29888066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science","raw_type":"Journal Article"},{"id":"mag:2990195982","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29888066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4944162","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961780","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2448904081","display_name":"National Infrastructure for Standardized and Portable EHR Phenotyping Algorithms","funder_award_id":"R01GM105688","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4704838373","display_name":"Informatics Tools for Pharmacogenomic Discovery using Practice-based Data","funder_award_id":"R01GM103859","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W141307743","https://openalex.org/W583528244","https://openalex.org/W1512691487","https://openalex.org/W1796210937","https://openalex.org/W1934602670","https://openalex.org/W1935683423","https://openalex.org/W1957326853","https://openalex.org/W1964978949","https://openalex.org/W1965072372","https://openalex.org/W1974971068","https://openalex.org/W1986051413","https://openalex.org/W1988152669","https://openalex.org/W1990765451","https://openalex.org/W1992656581","https://openalex.org/W2015038969","https://openalex.org/W2018352527","https://openalex.org/W2019688507","https://openalex.org/W2024751402","https://openalex.org/W2027856133","https://openalex.org/W2040935952","https://openalex.org/W2063280109","https://openalex.org/W2064337796","https://openalex.org/W2069435392","https://openalex.org/W2103273190","https://openalex.org/W2106883129","https://openalex.org/W2116678763","https://openalex.org/W2116868464","https://openalex.org/W2119443549","https://openalex.org/W2122732537","https://openalex.org/W2127856462","https://openalex.org/W2129844899","https://openalex.org/W2131660156","https://openalex.org/W2132073122","https://openalex.org/W2140074016","https://openalex.org/W2145578524","https://openalex.org/W2149908785","https://openalex.org/W2152922562","https://openalex.org/W2153150465","https://openalex.org/W2159317482","https://openalex.org/W2159482845","https://openalex.org/W2163780906","https://openalex.org/W2173969165","https://openalex.org/W2227148039","https://openalex.org/W2249991663","https://openalex.org/W2252794970","https://openalex.org/W2317648909","https://openalex.org/W2318605753","https://openalex.org/W2338021849","https://openalex.org/W2385169442","https://openalex.org/W2466271535","https://openalex.org/W2470078220","https://openalex.org/W2541932182","https://openalex.org/W2555338771","https://openalex.org/W2591131474","https://openalex.org/W2617871421","https://openalex.org/W2915667579"],"related_works":["https://openalex.org/W3166661276","https://openalex.org/W3020825494","https://openalex.org/W7075728952","https://openalex.org/W2783654878","https://openalex.org/W1964978949","https://openalex.org/W2591131474","https://openalex.org/W2800628510","https://openalex.org/W7127389703","https://openalex.org/W2320015066","https://openalex.org/W2769674691"],"abstract_inverted_index":{".":[0],"CATCH-KB":[1,41,61],"currently":[2],"contains":[3],"information":[4,32],"on":[5],"49":[6],"research":[7],"papers":[8],"published":[9],"between":[10],"2004":[11],"and":[12,33,46,49],"2017":[13],"investigating":[14],"a":[15],"total":[16],"of":[17,55],"2,210":[18],"variants":[19],"in":[20,58],"over":[21],"280":[22],"genes":[23],"for":[24],"an":[25],"association":[26],"with":[27],"CIC.":[28,60],"By":[29],"centralizing":[30],"this":[31],"linking":[34],"it":[35],"to":[36],"external":[37],"open-access":[38],"biomedical":[39],"resources,":[40],"will":[42,50],"facilitate":[43],"hypothesis":[44],"generation":[45],"meta-analysis":[47],"efforts":[48],"ultimately":[51],"accelerate":[52],"the":[53],"use":[54],"genetic":[56],"screening":[57],"preventing":[59],"is":[62],"publicly":[63],"accessible":[64],"via":[65],"http://catchkb.org.":[66]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-12-05T00:00:00"}