{"id":"https://openalex.org/W2990153591","doi":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","title":"Role of penehyclidine in acute organophosphorus pesticide poisoning","display_name":"Role of penehyclidine in acute organophosphorus pesticide poisoning","publication_year":2019,"publication_date":"2019-11-25","ids":{"openalex":"https://openalex.org/W2990153591","doi":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","mag":"2990153591","pmid":"https://pubmed.ncbi.nlm.nih.gov/31893002","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6885584"},"language":"en","primary_location":{"id":"doi:10.5847/wjem.j.1920-8642.2020.01.006","doi":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","is_oa":true,"landing_page_url":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","pdf_url":"http://wjem.com.cn//EN/article/downloadArticleFile.do?attachType=PDF&id=6","source":{"id":"https://openalex.org/S2764653636","display_name":"World Journal of Emergency Medicine","issn_l":"1920-8642","issn":["1920-8642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","oarl","poland-140","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Emergency Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://wjem.com.cn//EN/article/downloadArticleFile.do?attachType=PDF&id=6","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103247271","display_name":"Shiyuan Yu","orcid":"https://orcid.org/0000-0003-2542-5091","observed_orcids":["https://orcid.org/0000-0003-2542-5091"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shi-yuan Yu","raw_affiliation_strings":["Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I2801228662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047420615","display_name":"Yanxia Gao","orcid":"https://orcid.org/0000-0001-8490-8494","observed_orcids":["https://orcid.org/0000-0001-8490-8494"]},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan-xia Gao","raw_affiliation_strings":["Department of Emergency Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055255943","display_name":"Joseph Harold Walline","orcid":"https://orcid.org/0000-0001-9582-1044","observed_orcids":["https://orcid.org/0000-0001-9582-1044"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Joseph Walline","raw_affiliation_strings":["Accident and Emergency Medicine Academic Unit, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Accident and Emergency Medicine Academic Unit, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008965883","display_name":"Xin Lu","orcid":"https://orcid.org/0000-0002-6272-0017","observed_orcids":["https://orcid.org/0000-0002-6272-0017"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Lu","raw_affiliation_strings":["Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I2801228662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039566796","display_name":"Lina Zhao","orcid":"https://orcid.org/0000-0002-1053-6824","observed_orcids":["https://orcid.org/0000-0002-1053-6824"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li-na Zhao","raw_affiliation_strings":["Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I2801228662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024445890","display_name":"Yuan-xu Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I144581915","display_name":"Jishou University","ror":"https://ror.org/056szk247","country_code":"CN","type":"education","lineage":["https://openalex.org/I144581915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan-xu Huang","raw_affiliation_strings":["Department of Emergency Medicine, the Fourth Affiliated Hospital of Jishou University, Huaihua, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, the Fourth Affiliated Hospital of Jishou University, Huaihua, China","institution_ids":["https://openalex.org/I144581915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074707275","display_name":"Jiang Tao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I144581915","display_name":"Jishou University","ror":"https://ror.org/056szk247","country_code":"CN","type":"education","lineage":["https://openalex.org/I144581915"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiang Tao","raw_affiliation_strings":["Department of Emergency Medicine, the Fourth Affiliated Hospital of Jishou University, Huaihua, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, the Fourth Affiliated Hospital of Jishou University, Huaihua, China","institution_ids":["https://openalex.org/I144581915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065552697","display_name":"An-yong Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I182386381","display_name":"Zunyi Medical University","ror":"https://ror.org/00g5b0g93","country_code":"CN","type":"education","lineage":["https://openalex.org/I182386381"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"An-yong Yu","raw_affiliation_strings":["Department of Emergency Medicine, the First Affiliated Hospital of Zunyi Medical University, Zunyi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, the First Affiliated Hospital of Zunyi Medical University, Zunyi, China","institution_ids":["https://openalex.org/I182386381"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Na Ta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121023","display_name":"Chifeng Municipal Hospital","ror":"https://ror.org/02j136k79","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121023"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Na Ta","raw_affiliation_strings":["Department of Emergency Medicine, Chifeng Municipal Hospital, Chifeng, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Chifeng Municipal Hospital, Chifeng, China","institution_ids":["https://openalex.org/I4210121023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075401107","display_name":"Ren-ju Xiao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ren-ju Xiao","raw_affiliation_strings":["Department of Emergency Medicine, Xingyi People's Hospital, Xingyi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Xingyi People's Hospital, Xingyi, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100421614","display_name":"Yi W. Li","orcid":"https://orcid.org/0000-0002-7158-3624","observed_orcids":["https://orcid.org/0000-0002-7158-3624"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I2801228662","display_name":"Peking Union Medical College Hospital","ror":"https://ror.org/04jztag35","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801228662"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Li","raw_affiliation_strings":["Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I2801228662"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1046,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.74359588,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"11","issue":"1","first_page":"37","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.9448000192642212,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.9448000192642212,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.04600000008940697,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/penehyclidine","display_name":"penehyclidine","score":0.9919999837875366},{"id":"https://openalex.org/keywords/organophosphorus-pesticide-poisoning","display_name":"organophosphorus pesticide poisoning","score":0.9679999947547913},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.8980000019073486},{"id":"https://openalex.org/keywords/anticholinergic-drugs","display_name":"anticholinergic agents","score":0.859000027179718},{"id":"https://openalex.org/keywords/atropinization","display_name":"atropinization","score":0.9160000085830688},{"id":"https://openalex.org/keywords/intermediate-syndrome","display_name":"intermediate syndrome","score":0.9900000095367432},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.8050000071525574},{"id":"https://openalex.org/keywords/cure-rate","display_name":"cure rate","score":0.7269999980926514},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8930000066757202},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7279999852180481},{"id":"https://openalex.org/keywords/atropine-overdose","display_name":"atropine overdose","score":0.40299999713897705}],"concepts":[{"id":"https://openalex.org/C2775859210","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine","level":2,"score":0.9652338624000549},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8742339611053467},{"id":"https://openalex.org/C2778689640","wikidata":"https://www.wikidata.org/wiki/Q113259","display_name":"Anticholinergic","level":2,"score":0.6391714215278625},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6012387275695801},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5103420615196228},{"id":"https://openalex.org/C2994123057","wikidata":"https://www.wikidata.org/wiki/Q1595418","display_name":"Cure rate","level":2,"score":0.5063596963882446},{"id":"https://openalex.org/C2776291473","wikidata":"https://www.wikidata.org/wiki/Q3363684","display_name":"Parasympatholytic","level":4,"score":0.41977107524871826},{"id":"https://openalex.org/C2779365888","wikidata":"https://www.wikidata.org/wiki/Q194168","display_name":"Antidote","level":3,"score":0.413646936416626},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3373420834541321},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.09492862224578857},{"id":"https://openalex.org/C33789571","wikidata":"https://www.wikidata.org/wiki/Q410959","display_name":"Muscarinic acetylcholine receptor","level":3,"score":0.07174620032310486},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5847/wjem.j.1920-8642.2020.01.006","doi":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","is_oa":true,"landing_page_url":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","pdf_url":"http://wjem.com.cn//EN/article/downloadArticleFile.do?attachType=PDF&id=6","source":{"id":"https://openalex.org/S2764653636","display_name":"World Journal of Emergency Medicine","issn_l":"1920-8642","issn":["1920-8642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","oarl","poland-140","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Emergency Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6885584","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6885584","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World J Emerg Med","raw_type":"Text"},{"id":"pmid:31893002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31893002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of emergency medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5847/wjem.j.1920-8642.2020.01.006","doi":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","is_oa":true,"landing_page_url":"https://doi.org/10.5847/wjem.j.1920-8642.2020.01.006","pdf_url":"http://wjem.com.cn//EN/article/downloadArticleFile.do?attachType=PDF&id=6","source":{"id":"https://openalex.org/S2764653636","display_name":"World Journal of Emergency Medicine","issn_l":"1920-8642","issn":["1920-8642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","oarl","poland-140","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Emergency Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2990153591.pdf","grobid_xml":"https://content.openalex.org/works/W2990153591.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1978138084","https://openalex.org/W1995420920","https://openalex.org/W2001894382","https://openalex.org/W2012657271","https://openalex.org/W2034988504","https://openalex.org/W2050054042","https://openalex.org/W2080558185","https://openalex.org/W2083844228","https://openalex.org/W2122139102","https://openalex.org/W2142424976","https://openalex.org/W2175283318","https://openalex.org/W2251683931","https://openalex.org/W2267892489","https://openalex.org/W2325689752","https://openalex.org/W2612183699","https://openalex.org/W2768845917","https://openalex.org/W2772062488","https://openalex.org/W2793578740","https://openalex.org/W2795355969","https://openalex.org/W3025128361"],"related_works":["https://openalex.org/W3030536847","https://openalex.org/W2348521856","https://openalex.org/W2387857132","https://openalex.org/W2369919068","https://openalex.org/W3029780136","https://openalex.org/W2370639335","https://openalex.org/W2393710213","https://openalex.org/W3029477203","https://openalex.org/W2392935748","https://openalex.org/W4306319767"],"abstract_inverted_index":{"BACKGROUND:":[0],"Penehyclidine":[1,239],"is":[2,243],"a":[3,185,190,245],"newly":[4],"developed":[5],"anticholinergic":[6],"agent.":[7],"We":[8,24],"aimed":[9],"to":[10,63,66,169,203,227],"investigate":[11],"the":[12,26,94,105,132,167,174,179,198,221],"role":[13],"of":[14,73,79,176,181,188,193,209,237],"penehyclidine":[15,102,160,194,215],"in":[16,161],"acute":[17,48],"organophosphorus":[18],"pesticide":[19],"poisoning":[20],"(OP)":[21],"patients.":[22],"METHODS:":[23],"searched":[25],"Pubmed,":[27],"Cochrane":[28],"library,":[29],"EMBASE,":[30],"Chinese":[31,36],"National":[32],"Knowledge":[33],"Infrastructure":[34],"(CNKI),":[35],"Biomedical":[37],"literature":[38],"(CBM)":[39],"and":[40,77,130,171,178,207,235],"Wanfang":[41],"databases.":[42],"Randomized":[43],"controlled":[44],"trials":[45],"(RCTs)":[46],"recruiting":[47],"OP":[49,162,217,250],"patients":[50,89,163,218,251],"were":[51,90],"identified":[52],"for":[53,249],"meta-analysis.":[54],"Main":[55],"outcomes":[56],"included":[57],"cure":[58,106,199,222],"rate,":[59,61,200,223,225,232],"mortality":[60,133,224],"time":[62,65,168,226],"atropinization,":[64,204,228],"60%":[67],"normal":[68],"acetylcholinesterase":[69],"(AchE)":[70],"level,":[71],"rate":[72,78,107,134,175,180,208],"intermediate":[74],"syndrome":[75],"(IMS)":[76],"adverse":[80],"drug":[81],"reactions":[82],"(ADR).":[83],"RESULTS:":[84],"Sixteen":[85],"RCTs":[86],"involving":[87],"1,334":[88],"identified.":[91],"Compared":[92,183],"with":[93,101,159,184,214,241],"atropine-":[95],"or":[96],"penehyclidine-alone":[97],"groups,":[98],"atropine":[99,242,253],"combined":[100,158,213,240],"significantly":[103,196],"increased":[104],"(penehyclidine+atropine":[108,135],"vs.":[109,112,120,123,136,139,147,150],"atropine,":[110,137,189],"0.97":[111],"0.86,":[113],"RR":[114,125,141,152],"1.13,":[115],"95%":[116,127,143,154],"CI":[117,128,144,155],"[1.07-1.19];":[118],"penehyclidine+atropine":[119,146],"penehyclidine,":[121,148],"0.93":[122],"0.80,":[124],"1.08,":[126],"[1.01-1.15])":[129],"reduced":[131,201],"0.015":[138],"0.11,":[140],"0.17,":[142],"[0.06-0.49];":[145],"0.13":[149],"0.08,":[151],"0.23,":[153],"[0.04-1.28]).":[156],"Atropine":[157,212],"also":[164,195],"helped":[165],"reduce":[166],"atropinization":[170],"AchE":[172,205,229],"recovery,":[173,206,230],"IMS":[177,231],"ADR.":[182],"single":[186,191],"dose":[187,192],"elevated":[197],"times":[202],"IMS.":[210],"CONCLUSION:":[211],"benefits":[216],"by":[219],"enhancing":[220],"total":[233],"ADR":[234],"duration":[236],"hospitalization.":[238],"likely":[244],"better":[246],"initial":[247],"therapy":[248],"than":[252],"alone.":[254]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2019-12-05T00:00:00"}