{"id":"https://openalex.org/W2990072144","doi":null,"title":"[Divergent functions of the calcium-sensing receptor other than regulation ofmineral metabolism.]","display_name":"[Divergent functions of the calcium-sensing receptor other than regulation ofmineral metabolism.]","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2990072144","mag":"2990072144","pmid":"https://pubmed.ncbi.nlm.nih.gov/28336825"},"language":"ja","primary_location":{"id":"pmid:28336825","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28336825","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical calcium","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103935988","display_name":"Daisuke Inoue","orcid":"https://orcid.org/0009-0005-5842-2147","observed_orcids":["https://orcid.org/0009-0005-5842-2147"]},"institutions":[{"id":"https://openalex.org/I4210131333","display_name":"Teikyo University Chiba Medical Center","ror":"https://ror.org/03edth057","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210131333"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Daisuke Inoue","raw_affiliation_strings":["Third Department of Medicine, Teikyo University Chiba Medical Center, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Medicine, Teikyo University Chiba Medical Center, Japan","institution_ids":["https://openalex.org/I4210131333"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103935988"],"corresponding_institution_ids":["https://openalex.org/I4210131333"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"4","first_page":"499","last_page":"505"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.09300000220537186,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.016699999570846558,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/calcium-sensing-receptor","display_name":"calcium-sensing receptor","score":1.0},{"id":"https://openalex.org/keywords/g-protein-coupled-receptors","display_name":"G protein-coupled receptors","score":0.8809999823570251},{"id":"https://openalex.org/keywords/extracellular-calcium","display_name":"extracellular calcium","score":0.7360000014305115},{"id":"https://openalex.org/keywords/mineral-metabolism","display_name":"mineral metabolism","score":0.765999972820282},{"id":"https://openalex.org/keywords/parathyroid-glands","display_name":"parathyroid glands","score":0.8140000104904175},{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":0.9810000061988831},{"id":"https://openalex.org/keywords/lung","display_name":"lung","score":0.6800000071525574},{"id":"https://openalex.org/keywords/neurons","display_name":"neurons","score":0.972000002861023},{"id":"https://openalex.org/keywords/endocrine-pancreas","display_name":"endocrine pancreas","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C142590548","wikidata":"https://www.wikidata.org/wiki/Q417801","display_name":"Calcium-sensing receptor","level":4,"score":0.9435577392578125},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.7421139478683472},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6921612024307251},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6574003100395203},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.46870988607406616},{"id":"https://openalex.org/C135285700","wikidata":"https://www.wikidata.org/wiki/Q38173","display_name":"G protein-coupled receptor","level":3,"score":0.4339454174041748},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42172810435295105},{"id":"https://openalex.org/C87975464","wikidata":"https://www.wikidata.org/wiki/Q910704","display_name":"Calcium metabolism","level":3,"score":0.3982032537460327},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.388680100440979},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.35753118991851807},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3380470275878906},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32356733083724976},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14577403664588928}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007413","descriptor_name":"Intestinal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044169","descriptor_name":"Receptors, Calcium-Sensing","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058847","descriptor_name":"Inflammasomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:28336825","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28336825","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical calcium","raw_type":"Journal Article"},{"id":"mag:2990072144","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28336825","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W41516964","https://openalex.org/W58690323","https://openalex.org/W93053989","https://openalex.org/W1501473386","https://openalex.org/W1547733031","https://openalex.org/W1594144334","https://openalex.org/W2008492357","https://openalex.org/W2014707628","https://openalex.org/W2045562495","https://openalex.org/W2066613071","https://openalex.org/W2098511755","https://openalex.org/W2100604852","https://openalex.org/W2101503666","https://openalex.org/W2105894548","https://openalex.org/W2142099365","https://openalex.org/W2144930991","https://openalex.org/W2150891147","https://openalex.org/W2172421250","https://openalex.org/W2337485820","https://openalex.org/W2409360547","https://openalex.org/W2409679560","https://openalex.org/W2414044484","https://openalex.org/W2508997451","https://openalex.org/W2520211681","https://openalex.org/W2542822064","https://openalex.org/W2769671204","https://openalex.org/W2791309620","https://openalex.org/W2895903821","https://openalex.org/W2909894833","https://openalex.org/W2981617674","https://openalex.org/W2990840371","https://openalex.org/W3016852213","https://openalex.org/W3016940380","https://openalex.org/W3025259451","https://openalex.org/W3028330817","https://openalex.org/W3034225365","https://openalex.org/W3035467903","https://openalex.org/W3036451283","https://openalex.org/W3092541624","https://openalex.org/W3147479802","https://openalex.org/W6776928405"],"related_works":["https://openalex.org/W66940619","https://openalex.org/W4254332153","https://openalex.org/W4379536820","https://openalex.org/W2170730872","https://openalex.org/W2339190587","https://openalex.org/W6995729111","https://openalex.org/W2026577576","https://openalex.org/W2981447058","https://openalex.org/W2526426930","https://openalex.org/W2590513639"],"abstract_inverted_index":{"The":[0],"calcium-sensing":[1],"receptor(CaSR)is":[2],"a":[3,15,29,43],"G":[4],"protein-coupled":[5],"membrane":[6],"receptor":[7],"that":[8],"binds":[9],"extracellular":[10,36],"Ca2+and":[11],"other":[12,48],"cations":[13],"as":[14,62,64],"ligand.":[16],"CaSR":[17,38,59],"is":[18,39],"expressed":[19,41],"in":[20,32,60],"parathyroid":[21],"glands":[22],"at":[23],"the":[24,33],"highest":[25],"level":[26],"and":[27,71],"plays":[28],"critical":[30],"role":[31],"regulation":[34],"of":[35,46,58],"calcium.":[37],"also":[40],"by":[42],"wide":[44],"variety":[45],"tissues":[47,66],"than":[49],"calcium":[50],"metabolic":[51],"organs.":[52],"In":[53],"this":[54],"overview,":[55],"divergent":[56],"roles":[57],"inflammasome":[61],"well":[63],"various":[65],"including":[67],"intestines,":[68],"lungs,":[69],"neurons":[70],"endocrine":[72],"pancreas":[73],"will":[74],"be":[75],"briefly":[76],"summarized.":[77]},"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2019-12-05T00:00:00"}