{"id":"https://openalex.org/W2989765925","doi":null,"title":"A comparison of the convolution and TMR10 treatment planning algorithms for Gamma Knife\u00ae radiosurgery.","display_name":"A comparison of the convolution and TMR10 treatment planning algorithms for Gamma Knife\u00ae radiosurgery.","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2989765925","mag":"2989765925","pmid":"https://pubmed.ncbi.nlm.nih.gov/29657896","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5893456"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:4828226","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5893456","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5893456","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070010840","display_name":"Peter Fallows","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Fallows","raw_affiliation_strings":["Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gavin Wright","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gavin Wright","raw_affiliation_strings":["Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019622141","display_name":"Natalie Harrold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Natalie Harrold","raw_affiliation_strings":["Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2799390153"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011571875","display_name":"Peter J. Bownes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799390153","display_name":"Leeds Teaching Hospitals NHS Trust","ror":"https://ror.org/00v4dac24","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Bownes","raw_affiliation_strings":["Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leeds Cancer Centre, Leeds Teaching Hospitals, Leeds, United Kingdom","institution_ids":["https://openalex.org/I2799390153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2799390153"],"apc_list":null,"apc_paid":null,"fwci":1.6051,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.82494989,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"5","issue":"2","first_page":"157","last_page":"167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-knife-radiosurgery","display_name":"gamma knife radiosurgery","score":0.9779999852180481},{"id":"https://openalex.org/keywords/treatment-planning-algorithms","display_name":"treatment planning algorithms","score":0.847000002861023},{"id":"https://openalex.org/keywords/dose-calculation-accuracy","display_name":"dose calculation accuracy","score":0.6790000200271606},{"id":"https://openalex.org/keywords/heterogeneous-phantoms","display_name":"heterogeneous phantoms","score":0.8529999852180481},{"id":"https://openalex.org/keywords/metastasis-treatment","display_name":"metastasis treatment","score":0.4690000116825104},{"id":"https://openalex.org/keywords/gamma-analysis","display_name":"gamma analysis","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C45347329","wikidata":"https://www.wikidata.org/wiki/Q5166604","display_name":"Convolution (computer science)","level":3,"score":0.86759352684021},{"id":"https://openalex.org/C104293457","wikidata":"https://www.wikidata.org/wiki/Q28324852","display_name":"Imaging phantom","level":2,"score":0.7181388139724731},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5696784853935242},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5099467039108276},{"id":"https://openalex.org/C204323151","wikidata":"https://www.wikidata.org/wiki/Q905424","display_name":"Range (aeronautics)","level":2,"score":0.47896555066108704},{"id":"https://openalex.org/C66882249","wikidata":"https://www.wikidata.org/wiki/Q169336","display_name":"Homogeneous","level":2,"score":0.47881561517715454},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.46314024925231934},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.44207850098609924},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.42594099044799805},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34090977907180786},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21342983841896057},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.18438684940338135},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.18103572726249695},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.10454168915748596},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.08328109979629517},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.07932785153388977},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:4828226","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5893456","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5893456","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5893456","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Radiosurg SBRT","raw_type":"Text"},{"id":"pmid:29657896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29657896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of radiosurgery and SBRT","raw_type":"Journal Article"},{"id":"mag:2989765925","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29657896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4828226","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5893456","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8027999997138977}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7300000190734863}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1980941739","https://openalex.org/W2009680874","https://openalex.org/W2086124133","https://openalex.org/W2091591227","https://openalex.org/W2149710876","https://openalex.org/W2173170004","https://openalex.org/W2551949713","https://openalex.org/W2731279912"],"related_works":["https://openalex.org/W2055857046","https://openalex.org/W2948433462","https://openalex.org/W1995258111","https://openalex.org/W3010815320","https://openalex.org/W2091591227","https://openalex.org/W2551949713","https://openalex.org/W4383483770","https://openalex.org/W2772272682","https://openalex.org/W965224356","https://openalex.org/W1977626073"],"abstract_inverted_index":{"AIMS:":[0],"To":[1],"compare":[2],"the":[3,6,17,67,144],"accuracies":[4],"of":[5,22,95,113,132,140,173],"convolution":[7,83,159],"and":[8,15,41,70,105],"TMR10":[9,86,124,154],"Gamma":[10,103],"Knife":[11],"treatment":[12,25],"planning":[13,76],"algorithms,":[14],"assess":[16],"impact":[18],"upon":[19],"clinical":[20],"practice":[21],"implementing":[23],"convolution-based":[24],"planning.":[26],"METHODS:":[27],"Doses":[28],"calculated":[29,47],"by":[30,48],"both":[31,49],"algorithms":[32,50],"were":[33,51,108],"compared":[34,52,78],"against":[35,53,85],"ionisation":[36],"chamber":[37],"measurements":[38],"in":[39,58,143,155,162],"homogeneous":[40],"heterogeneous":[42,60,156],"phantoms.":[43],"Relative":[44],"dose":[45,114,141],"distributions":[46],"film-derived":[54],"2D":[55],"isodose":[56,72],"plots":[57],"a":[59,171],"phantom,":[61],"with":[62,88],"distance-to-agreement":[63],"(DTA)":[64],"measured":[65],"at":[66],"80%,":[68],"50%":[69],"20%":[71],"levels.":[73],"A":[74],"retrospective":[75],"study":[77],"19":[79],"clinically":[80],"acceptable":[81],"metastasis":[82],"plans":[84,87],"matched":[89,123],"shot":[90,122],"times,":[91],"allowing":[92],"novel":[93],"comparison":[94],"true":[96],"dosimetric":[97],"parameters":[98],"rather":[99],"than":[100,121],"total":[101],"beam-on-time.":[102],"analysis":[104,107],"dose-difference":[106],"performed":[109],"on":[110],"each":[111],"pair":[112],"distributions.":[115],"RESULTS:":[116],"6.4%":[117],"(95%":[118],"CI:5.5%-7.3%,p<0.001)":[119],"less":[120],"plans.":[125],"For":[126],"gamma":[127],"passing":[128,135],"criteria":[129],"1%/1mm,":[130],"16%":[131],"targets":[133,145],"had":[134],"rates":[136],">95%.":[137],"The":[138],"range":[139],"differences":[142],"was":[146],"0.2-4.6Gy.":[147],"CONCLUSIONS:":[148],"Convolution":[149],"provides":[150],"superior":[151],"accuracy":[152],"versus":[153],"conditions.":[157],"Implementing":[158],"would":[160],"result":[161],"increased":[163],"target":[164],"doses":[165],"therefore":[166],"its":[167],"implementation":[168],"may":[169],"require":[170],"revaluation":[172],"prescription":[174],"doses.":[175]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2019-12-05T00:00:00"}
