{"id":"https://openalex.org/W2989613293","doi":"https://doi.org/10.1161/hypertensionaha.119.13580","title":"Severity of Hypertension Mediates the Association of Hyperuricemia With Stroke in the REGARDS Case Cohort Study","display_name":"Severity of Hypertension Mediates the Association of Hyperuricemia With Stroke in the REGARDS Case Cohort Study","publication_year":2019,"publication_date":"2019-12-02","ids":{"openalex":"https://openalex.org/W2989613293","doi":"https://doi.org/10.1161/hypertensionaha.119.13580","mag":"2989613293","pmid":"https://pubmed.ncbi.nlm.nih.gov/31786980"},"language":"en","primary_location":{"id":"doi:10.1161/hypertensionaha.119.13580","doi":"https://doi.org/10.1161/hypertensionaha.119.13580","is_oa":true,"landing_page_url":"https://doi.org/10.1161/hypertensionaha.119.13580","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.119.13580","source":{"id":"https://openalex.org/S67880631","display_name":"Hypertension","issn_l":"0194-911X","issn":["0194-911X","1524-4563"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hypertension","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.119.13580","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066807976","display_name":"Ninad S. Chaudhary","orcid":"https://orcid.org/0000-0003-1350-1093","observed_orcids":["https://orcid.org/0000-0003-1350-1093"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ninad S. Chaudhary","raw_affiliation_strings":["From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","Ninad S. Chaudhary From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Ninad S. Chaudhary From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090731148","display_name":"S. Louis Bridges","orcid":"https://orcid.org/0000-0003-3785-1389","observed_orcids":["https://orcid.org/0000-0003-3785-1389"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Louis Bridges","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","S. Louis Bridges Jr Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"S. Louis Bridges Jr Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046382845","display_name":"Kenneth G. Saag","orcid":"https://orcid.org/0000-0001-6189-8078","observed_orcids":["https://orcid.org/0000-0001-6189-8078"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth G. Saag","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Kenneth G. Saag Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Kenneth G. Saag Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071641808","display_name":"Elizabeth J. Rahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth J. Rahn","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Elizabeth J. Rahn Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Elizabeth J. Rahn Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000754711","display_name":"Jeffrey R. Curtis","orcid":"https://orcid.org/0000-0002-8907-8976","observed_orcids":["https://orcid.org/0000-0002-8907-8976"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey R. Curtis","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Jeffrey R. Curtis Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Jeffrey R. Curtis Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085175821","display_name":"Angelo Gaffo","orcid":"https://orcid.org/0000-0001-7365-7212","observed_orcids":["https://orcid.org/0000-0001-7365-7212"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4210115616","display_name":"Birmingham VA Medical Center","ror":"https://ror.org/0242qs713","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210115616","https://openalex.org/I4210131075"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angelo Gaffo","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","Angelo Gaffo Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","institution_ids":["https://openalex.org/I4210115616"]},{"raw_affiliation_string":"Angelo Gaffo Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","institution_ids":["https://openalex.org/I4210115616","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079771081","display_name":"Nita A. Limdi","orcid":"https://orcid.org/0000-0002-4672-8406","observed_orcids":["https://orcid.org/0000-0002-4672-8406"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nita A. Limdi","raw_affiliation_strings":["Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham","Nita A. Limdi Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Nita A. Limdi Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061452200","display_name":"Emily B. Levitan","orcid":"https://orcid.org/0000-0002-5429-3852","observed_orcids":["https://orcid.org/0000-0002-5429-3852"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily B. Levitan","raw_affiliation_strings":["From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","Emily B. Levitan From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Emily B. Levitan From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046999547","display_name":"Jasvinder A. Singh","orcid":"https://orcid.org/0000-0003-3485-0006","observed_orcids":["https://orcid.org/0000-0003-3485-0006"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4210115616","display_name":"Birmingham VA Medical Center","ror":"https://ror.org/0242qs713","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210115616","https://openalex.org/I4210131075"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jasvinder A. Singh","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","Jasvinder A. Singh Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","institution_ids":["https://openalex.org/I4210115616"]},{"raw_affiliation_string":"Jasvinder A. Singh Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham Medicine Service, Birmingham VA Medical Center, AL (A.G., J.A.S.)","institution_ids":["https://openalex.org/I4210115616","https://openalex.org/I4390039250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056799708","display_name":"Lisandro Dami\u00e1n Colantonio","orcid":"https://orcid.org/0000-0001-8742-1788","observed_orcids":["https://orcid.org/0000-0001-8742-1788"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisandro D. Colantonio","raw_affiliation_strings":["From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","Lisandro D. Colantonio From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Lisandro D. Colantonio From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088595592","display_name":"George Howard","orcid":"https://orcid.org/0000-0002-3068-5720","observed_orcids":["https://orcid.org/0000-0002-3068-5720"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George Howard","raw_affiliation_strings":["Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","George Howard Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"George Howard Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023858070","display_name":"Mary Cushman","orcid":"https://orcid.org/0000-0002-7871-6143","observed_orcids":["https://orcid.org/0000-0002-7871-6143"]},"institutions":[{"id":"https://openalex.org/I2801980284","display_name":"University of Vermont Medical Center","ror":"https://ror.org/04cewr321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801980284"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Cushman","raw_affiliation_strings":["Department of Hematology, University of Vermont Medical Center, Burlington (M.C.)","Mary Cushman Department of Hematology, University of Vermont Medical Center, Burlington (M.C.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University of Vermont Medical Center, Burlington (M.C.)","institution_ids":["https://openalex.org/I2801980284"]},{"raw_affiliation_string":"Mary Cushman Department of Hematology, University of Vermont Medical Center, Burlington (M.C.)","institution_ids":["https://openalex.org/I2801980284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024175492","display_name":"Matthew L. Flaherty","orcid":"https://orcid.org/0000-0002-6247-010X","observed_orcids":["https://orcid.org/0000-0002-6247-010X"]},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew L. Flaherty","raw_affiliation_strings":["University of Cincinnati School of Medicine, OH (M.L.F.)","Matthew L. Flaherty University of Cincinnati School of Medicine, OH (M.L.F.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Cincinnati School of Medicine, OH (M.L.F.)","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Matthew L. Flaherty University of Cincinnati School of Medicine, OH (M.L.F.)","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076115498","display_name":"Suzanne E. Judd","orcid":"https://orcid.org/0000-0001-7594-6587","observed_orcids":["https://orcid.org/0000-0001-7594-6587"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne Judd","raw_affiliation_strings":["Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","Suzanne Judd Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Suzanne Judd Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.)","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062964883","display_name":"Marguerite R. Irvin","orcid":"https://orcid.org/0000-0002-1442-2023","observed_orcids":["https://orcid.org/0000-0002-1442-2023"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marguerite R. Irvin","raw_affiliation_strings":["From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","Marguerite R. Irvin From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]},{"raw_affiliation_string":"Marguerite R. Irvin From the Department of Epidemiology, School of Public Health (N.S.C., E.B.L., L.D.C., M.R.I.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101940499","display_name":"Richard J. Reynolds","orcid":"https://orcid.org/0000-0001-6419-7779","observed_orcids":["https://orcid.org/0000-0001-6419-7779"]},"institutions":[{"id":"https://openalex.org/I111236770","display_name":"University of Vermont","ror":"https://ror.org/0155zta11","country_code":"US","type":"education","lineage":["https://openalex.org/I111236770"]},{"id":"https://openalex.org/I17301866","display_name":"University of Alabama","ror":"https://ror.org/03xrrjk67","country_code":"US","type":"education","lineage":["https://openalex.org/I17301866"]},{"id":"https://openalex.org/I2801980284","display_name":"University of Vermont Medical Center","ror":"https://ror.org/04cewr321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801980284"]},{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]},{"id":"https://openalex.org/I4210115616","display_name":"Birmingham VA Medical Center","ror":"https://ror.org/0242qs713","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210115616","https://openalex.org/I4210131075"]},{"id":"https://openalex.org/I4390039250","display_name":"UAB Medicine","ror":"https://ror.org/036554539","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I4390039250"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Richard J. Reynolds","raw_affiliation_strings":["Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.); Department of Hematology, University of Vermont Medical Center, Burlington (M.C.);","Department of Epidemiology, School of Public Health (N","Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham; Medicine Service, Birmingham VA Medical Center, AL","Division of Clinical Immunology and Rheumatology (","University of Alabama School of Medicine, 1852 University Blvd, Birmingham, Al 35233","University of Cincinnati School of Medicine, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (S.L.B., K.G.S., E.J.R., J.R.C., A.G., R.J.R., J.A.S.), University of Alabama at Birmingham","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Department of Biostatistics, School of Public Health of Alabama at Birmingham (G.H., S.J.); Department of Hematology, University of Vermont Medical Center, Burlington (M.C.);","institution_ids":["https://openalex.org/I111236770","https://openalex.org/I2801980284","https://openalex.org/I32389192"]},{"raw_affiliation_string":"Department of Epidemiology, School of Public Health (N","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, School of Medicine (N.A.L.), University of Alabama at Birmingham; Medicine Service, Birmingham VA Medical Center, AL","institution_ids":["https://openalex.org/I32389192","https://openalex.org/I4210115616","https://openalex.org/I4390039250"]},{"raw_affiliation_string":"Division of Clinical Immunology and Rheumatology (","institution_ids":[]},{"raw_affiliation_string":"University of Alabama School of Medicine, 1852 University Blvd, Birmingham, Al 35233","institution_ids":["https://openalex.org/I17301866","https://openalex.org/I32389192"]},{"raw_affiliation_string":"University of Cincinnati School of Medicine, OH","institution_ids":["https://openalex.org/I63135867"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5101940499"],"corresponding_institution_ids":["https://openalex.org/I111236770","https://openalex.org/I17301866","https://openalex.org/I2801980284","https://openalex.org/I32389192","https://openalex.org/I4210115616","https://openalex.org/I4390039250","https://openalex.org/I63135867"],"apc_list":null,"apc_paid":null,"fwci":5.2095,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.96207015,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"75","issue":"1","first_page":"246","last_page":"256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperuricemia","display_name":"hyperuricemia","score":1.0},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.8550000190734863},{"id":"https://openalex.org/keywords/hypertension-severity","display_name":"hypertension severity","score":0.7210000157356262},{"id":"https://openalex.org/keywords/treatment-resistant-hypertension","display_name":"treatment-resistant hypertension","score":0.9649999737739563},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.9150000214576721},{"id":"https://openalex.org/keywords/serum-uric-acid","display_name":"serum uric acid","score":0.8899999856948853},{"id":"https://openalex.org/keywords/mediation-analysis","display_name":"mediation analysis","score":0.8550000190734863},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.8320000171661377},{"id":"https://openalex.org/keywords/regards-study","display_name":"REGARDS study","score":0.8050000071525574}],"concepts":[{"id":"https://openalex.org/C2779721657","wikidata":"https://www.wikidata.org/wiki/Q49970","display_name":"Hyperuricemia","level":3,"score":0.9374282360076904},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9056401252746582},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.7830743789672852},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7169131636619568},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.715445339679718},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7021626234054565},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5765817761421204},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.574030339717865},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5288734436035156},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4482906460762024},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4457399249076843},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.3144601583480835},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.11988192796707153},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D033461","descriptor_name":"Hyperuricemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/hypertensionaha.119.13580","doi":"https://doi.org/10.1161/hypertensionaha.119.13580","is_oa":true,"landing_page_url":"https://doi.org/10.1161/hypertensionaha.119.13580","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.119.13580","source":{"id":"https://openalex.org/S67880631","display_name":"Hypertension","issn_l":"0194-911X","issn":["0194-911X","1524-4563"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hypertension","raw_type":"journal-article"},{"id":"pmid:31786980","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31786980","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hypertension (Dallas, Tex. : 1979)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:6685496","doi":null,"is_oa":false,"landing_page_url":"http://europepmc.org/pmc/articles/PMC7122733","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7122733","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7122733","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Hypertension","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1161/hypertensionaha.119.13580","doi":"https://doi.org/10.1161/hypertensionaha.119.13580","is_oa":true,"landing_page_url":"https://doi.org/10.1161/hypertensionaha.119.13580","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/HYPERTENSIONAHA.119.13580","source":{"id":"https://openalex.org/S67880631","display_name":"Hypertension","issn_l":"0194-911X","issn":["0194-911X","1524-4563"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hypertension","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8199999928474426}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1429240514","display_name":"VCID and Stroke in a Bi-racial National Cohort","funder_award_id":"5u01ns041588-21","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1442900148","display_name":null,"funder_award_id":"P30DK079626","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G1725353665","display_name":null,"funder_award_id":"K24HL133373","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G683916195","display_name":null,"funder_award_id":"P50-AR-060-772","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G6854337074","display_name":null,"funder_award_id":"R01HL092173","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7785385282","display_name":"INvestigations In Gout, Hyperuricemia, and comorbidiTies (INSIGHT) Center of Research Translation (CORT)","funder_award_id":"5p50ar060772-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G939786002","display_name":null,"funder_award_id":"U01 NS041588)","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2989613293.pdf","grobid_xml":"https://content.openalex.org/works/W2989613293.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W1200752817","https://openalex.org/W1757751439","https://openalex.org/W1963700573","https://openalex.org/W1964198430","https://openalex.org/W1964439201","https://openalex.org/W1968364422","https://openalex.org/W1984486405","https://openalex.org/W1984845078","https://openalex.org/W1985749449","https://openalex.org/W1989351453","https://openalex.org/W1996355835","https://openalex.org/W2001293211","https://openalex.org/W2002849282","https://openalex.org/W2010634472","https://openalex.org/W2019243843","https://openalex.org/W2020392093","https://openalex.org/W2024087337","https://openalex.org/W2031005241","https://openalex.org/W2043955249","https://openalex.org/W2047991430","https://openalex.org/W2053301665","https://openalex.org/W2067395123","https://openalex.org/W2072528042","https://openalex.org/W2077974673","https://openalex.org/W2083024896","https://openalex.org/W2087403652","https://openalex.org/W2088731733","https://openalex.org/W2090359115","https://openalex.org/W2093707453","https://openalex.org/W2099774808","https://openalex.org/W2111277253","https://openalex.org/W2114075168","https://openalex.org/W2114365596","https://openalex.org/W2122184484","https://openalex.org/W2125710993","https://openalex.org/W2132895884","https://openalex.org/W2134220846","https://openalex.org/W2138595885","https://openalex.org/W2141653683","https://openalex.org/W2153739619","https://openalex.org/W2160631219","https://openalex.org/W2169831409","https://openalex.org/W2193561325","https://openalex.org/W2233507690","https://openalex.org/W2252834308","https://openalex.org/W2335302945","https://openalex.org/W2560549015","https://openalex.org/W2599206788","https://openalex.org/W2606134018","https://openalex.org/W2896865390","https://openalex.org/W2909578528","https://openalex.org/W2913321579","https://openalex.org/W3174461150","https://openalex.org/W4212838134","https://openalex.org/W4235678124","https://openalex.org/W4251022474"],"related_works":["https://openalex.org/W4392812792","https://openalex.org/W2375522942","https://openalex.org/W3167171142","https://openalex.org/W3028648734","https://openalex.org/W2412642279","https://openalex.org/W3214382627","https://openalex.org/W2890068404","https://openalex.org/W2359673844","https://openalex.org/W3082828398","https://openalex.org/W2355917680"],"abstract_inverted_index":{"Previous":[0],"studies":[1],"do":[2],"not":[3],"widely":[4],"support":[5],"hyperuricemia":[6,22,184,213,224],"as":[7],"a":[8,29,47,227,252],"risk":[9,228],"factor":[10,229],"for":[11,38,120,230],"stroke":[12,25,51,111,215],"and":[13,23,40,53,58,75,93,123,125,172,192,199,214,242],"other":[14],"cardiovascular":[15,97],"diseases.":[16],"We":[17,45,221],"assessed":[18],"the":[19,34,65,101,173,181,202,210],"relationship":[20],"between":[21,212],"ischemic":[24,186],"(\u2248900":[26],"cases)":[27],"using":[28],"large":[30],"data":[31],"set":[32],"from":[33],"REGARDS":[35],"study":[36],"(Reasons":[37],"Geographic":[39],"Racial":[41],"Differences":[42],"in":[43,209],"Stroke).":[44],"employed":[46],"case-cohort":[48],"design":[49],"(incident":[50],"cases":[52],"randomly":[54],"selected":[55],"cohort":[56],"participants)":[57],"weighted":[59],"Cox-proportional":[60],"hazard":[61],"models":[62],"to":[63,77],"estimate":[64],"association":[66,104,130,211,237],"of":[67,96,168,175,183,194,201,235,244],"serum":[68,102],"urate":[69],"level":[70],"\u22656.8":[71],"mg/dL":[72,79,82],"(ie,":[73],"hyperuricemia)":[74],"6.0":[76],"<6.8":[78],"versus":[80],"<6.0":[81],"(reference)":[83],"with":[84,110],"incident":[85],"stroke.":[86,187,231],"Analyses":[87],"were":[88],"stratified":[89],"by":[90,140,216,238],"race,":[91,218],"gender,":[92],"age.":[94],"Mediation":[95],"disease":[98],"comorbidities":[99],"on":[100,162,185],"urate-stroke":[103],"was":[105,108,131,205],"tested.":[106],"Hyperuricemia":[107],"associated":[109],"(hazard":[112,134],"ratio,":[113,135],"1.40":[114],"[95%":[115,137],"CI,":[116,138],"1.10-1.78])":[117],"after":[118],"adjustment":[119],"demographic":[121],"variables":[122],"systolic":[124],"diastolic":[126,156],"blood":[127,150,157],"pressure.":[128],"This":[129],"substantially":[132],"attenuated":[133],"1.17":[136],"0.90-1.51])":[139],"additional":[141],"covariate":[142],"adjustment.":[143],"In":[144],"particular,":[145],"apparent":[146,189,239],"treatment-resistant":[147,190,240],"hypertension":[148,191,241,249],"(systolic":[149],"pressure":[151,158],"\u2265140":[152],"mm":[153,160],"Hg":[154,161],"or":[155,166,219],"\u226590":[159],"3":[163],"antihypertensive":[164,170,176,245],"medications":[165],"use":[167],"\u22654":[169],"medications)":[171],"count":[174],"medication":[177],"classes":[178],"significantly":[179],"reduced":[180],"effect":[182,207],"Specifically,":[188],"number":[193,243],"antihypertensive,":[195],"respectively,":[196],"mediate":[197],"45%":[198],"43%":[200],"association.":[203],"There":[204],"no":[206],"modification":[208],"age,":[217],"gender.":[220],"conclude":[222],"that":[223,247],"may":[225,250],"be":[226,251],"The":[232],"substantial":[233],"attenuation":[234],"this":[236],"suggests":[246],"severe":[248],"mediator.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":4}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}