{"id":"https://openalex.org/W2989609459","doi":"https://doi.org/10.1016/j.annder.2019.09.559","title":"X\u00e9rostomie induite par anti-PD1/PDL1 : caract\u00e9risation clinique, immunohistochimique et proposition de prise en charge","display_name":"X\u00e9rostomie induite par anti-PD1/PDL1 : caract\u00e9risation clinique, immunohistochimique et proposition de prise en charge","publication_year":2019,"publication_date":"2019-11-19","ids":{"openalex":"https://openalex.org/W2989609459","doi":"https://doi.org/10.1016/j.annder.2019.09.559","mag":"2989609459"},"language":"fr","primary_location":{"id":"doi:10.1016/j.annder.2019.09.559","doi":"https://doi.org/10.1016/j.annder.2019.09.559","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.annder.2019.09.559","pdf_url":null,"source":{"id":"https://openalex.org/S41786655","display_name":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie","issn_l":"0151-9638","issn":["0151-9638","2214-5451"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029308445","display_name":"\u00c9mmanuelle Vigarios","orcid":"https://orcid.org/0000-0002-3164-463X","observed_orcids":["https://orcid.org/0000-0002-3164-463X"]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"E.A. Vigarios","raw_affiliation_strings":["M\u00e9decine orale, institut universitaire du cancer Toulouse Oncopole, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M\u00e9decine orale, institut universitaire du cancer Toulouse Oncopole, Toulouse, France","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050203761","display_name":"Ariadna Ortiz\u2010Brugu\u00e9s","orcid":"https://orcid.org/0000-0001-6205-0941","observed_orcids":["https://orcid.org/0000-0001-6205-0941"]},"institutions":[{"id":"https://openalex.org/I4210121211","display_name":"Hospital Santa Caterina","ror":"https://ror.org/036dkm174","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210121211"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A. Ortiz Brugu\u00e9s","raw_affiliation_strings":["Dermatologie, h\u00f4pital Sta Caterina, Girone, Espagne"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dermatologie, h\u00f4pital Sta Caterina, Girone, Espagne","institution_ids":["https://openalex.org/I4210121211"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Epstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Epstein","raw_affiliation_strings":["Oral medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Health System, Los Angeles, \u00c9tats-Unis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oral medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Health System, Los Angeles, \u00c9tats-Unis","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084897187","display_name":"Bertrand Barres","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Barres","raw_affiliation_strings":["Anatomopathologie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anatomopathologie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065061478","display_name":"Sarah B\u00e9trian","orcid":"https://orcid.org/0000-0001-5369-9378","observed_orcids":["https://orcid.org/0000-0001-5369-9378"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Betrian","raw_affiliation_strings":["Oncologie m\u00e9dicale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncologie m\u00e9dicale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020724418","display_name":"Iphig\u00e9nie Korakis","orcid":"https://orcid.org/0000-0002-2112-5932","observed_orcids":["https://orcid.org/0000-0002-2112-5932"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. Korakis","raw_affiliation_strings":["Oncologie m\u00e9dicale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncologie m\u00e9dicale","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111144192","display_name":"Caroline de Bataille","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. de Bataille","raw_affiliation_strings":["M\u00e9decine orale, institut universitaire du cancer Toulouse Oncopole, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"M\u00e9decine orale, institut universitaire du cancer Toulouse Oncopole, Toulouse, France","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014438009","display_name":"C. Gomez Roca","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Gomez Roca","raw_affiliation_strings":["Oncologie m\u00e9dicale"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncologie m\u00e9dicale","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082390042","display_name":"Vincent Sibaud","orcid":"https://orcid.org/0000-0003-2585-6633","observed_orcids":["https://orcid.org/0000-0003-2585-6633"]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"V. Sibaud","raw_affiliation_strings":["Oncodermatologie, institut universitaire du cancer Toulouse Oncopole, Toulouse, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncodermatologie, institut universitaire du cancer Toulouse Oncopole, Toulouse, France","institution_ids":["https://openalex.org/I4210098740"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5029308445"],"corresponding_institution_ids":["https://openalex.org/I4210098740"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18021522,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"146","issue":"12","first_page":"A332","last_page":"A333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.6880000233650208,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.6880000233650208,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12198","display_name":"Oral health in cancer treatment","score":0.2653999924659729,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions","score":0.026000000536441803,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xerostomia","display_name":"xerostomia","score":0.8320000171661377},{"id":"https://openalex.org/keywords/pd-1-pd-l1-blockade","display_name":"PD-1/PD-L1 blockade","score":0.8889999985694885},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.8460000157356262},{"id":"https://openalex.org/keywords/immune-related-adverse-events","display_name":"immune-related adverse events","score":0.8399999737739563},{"id":"https://openalex.org/keywords/salivary-gland-biopsy","display_name":"salivary gland biopsy","score":0.7260000109672546},{"id":"https://openalex.org/keywords/lymphocytic-infiltration","display_name":"lymphocyte infiltration","score":0.906000018119812},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.8889999985694885},{"id":"https://openalex.org/keywords/prednisolone","display_name":"prednisolone","score":0.8090000152587891},{"id":"https://openalex.org/keywords/immunosuppressive-therapy","display_name":"immunosuppressive therapy","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8709279298782349},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.5399662256240845}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.annder.2019.09.559","doi":"https://doi.org/10.1016/j.annder.2019.09.559","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.annder.2019.09.559","pdf_url":null,"source":{"id":"https://openalex.org/S41786655","display_name":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie","issn_l":"0151-9638","issn":["0151-9638","2214-5451"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2552482409","https://openalex.org/W2902206124","https://openalex.org/W2550605958","https://openalex.org/W2549246533","https://openalex.org/W2945041753","https://openalex.org/W4311394552","https://openalex.org/W2553935741","https://openalex.org/W3108490924","https://openalex.org/W4388761051","https://openalex.org/W2754630785"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-12-05T00:00:00"}