{"id":"https://openalex.org/W2989170628","doi":"https://doi.org/10.7554/elife.03406.010","title":"Author response: Direct measurement of the mechanical work during translocation by the ribosome","display_name":"Author response: Direct measurement of the mechanical work during translocation by the ribosome","publication_year":2014,"publication_date":"2014-07-10","ids":{"openalex":"https://openalex.org/W2989170628","doi":"https://doi.org/10.7554/elife.03406.010","mag":"2989170628"},"language":"en","primary_location":{"id":"doi:10.7554/elife.03406.010","doi":"https://doi.org/10.7554/elife.03406.010","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.03406.010","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.03406.010","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Tingting Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tingting Liu","raw_affiliation_strings":["Department of Physics, University of California, Berkeley","Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055748555","display_name":"Ariel Kaplan","orcid":"https://orcid.org/0000-0002-9731-6962","observed_orcids":["https://orcid.org/0000-0002-9731-6962"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Ariel Kaplan","raw_affiliation_strings":["Department of Physics, University of California, Berkeley","Faculty of Biology, Technion-Israel Institute of Technology","Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley","Lorry I Lokey Interdisciplinary Center, Technion-Israel Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Faculty of Biology, Technion-Israel Institute of Technology","institution_ids":["https://openalex.org/I174306211"]},{"raw_affiliation_string":"Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Lorry I Lokey Interdisciplinary Center, Technion-Israel Institute of Technology","institution_ids":["https://openalex.org/I174306211"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lisa Alexander","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa Alexander","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014664746","display_name":"Shannon Yan","orcid":"https://orcid.org/0000-0001-7994-9427","observed_orcids":["https://orcid.org/0000-0001-7994-9427"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon Yan","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027198000","display_name":"Jin\u2010Der Wen","orcid":"https://orcid.org/0000-0001-8317-4329","observed_orcids":["https://orcid.org/0000-0001-8317-4329"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jin-Der Wen","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085910904","display_name":"Laura Lancaster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Lancaster","raw_affiliation_strings":["Center for Molecular Biology of RNA, University of California, Santa Cruz","Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Biology of RNA, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002956008","display_name":"C. E. Wickersham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles E Wickersham","raw_affiliation_strings":["Department of Physics, University of California, Berkeley","Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031416408","display_name":"Kurt L. Fredrick","orcid":"https://orcid.org/0000-0002-5115-6641","observed_orcids":["https://orcid.org/0000-0002-5115-6641"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kurt Fredrick","raw_affiliation_strings":["Center for Molecular Biology of RNA, University of California, Santa Cruz","Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Biology of RNA, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089776171","display_name":"Harry F. Noller","orcid":"https://orcid.org/0000-0002-2299-8700","observed_orcids":["https://orcid.org/0000-0002-2299-8700"]},"institutions":[{"id":"https://openalex.org/I185103710","display_name":"University of California, Santa Cruz","ror":"https://ror.org/03s65by71","country_code":"US","type":"education","lineage":["https://openalex.org/I185103710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry Noller","raw_affiliation_strings":["Center for Molecular Biology of RNA, University of California, Santa Cruz","Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Molecular Biology of RNA, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]},{"raw_affiliation_string":"Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz","institution_ids":["https://openalex.org/I185103710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111538822","display_name":"Ignacio Tinoco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ignacio Tinoco","raw_affiliation_strings":["Department of Chemistry, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010743284","display_name":"Carlos Bustamante","orcid":"https://orcid.org/0000-0002-2970-0073","observed_orcids":["https://orcid.org/0000-0002-2970-0073"]},"institutions":[{"id":"https://openalex.org/I103922791","display_name":"QB3","ror":"https://ror.org/04n1n3n22","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I103922791","https://openalex.org/I180670191","https://openalex.org/I185103710","https://openalex.org/I95457486"]},{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlos J Bustamante","raw_affiliation_strings":["California Institute for Quantitative Biosciences, University of California, Berkeley","Department of Chemistry, University of California, Berkeley","Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley","Department of Physics, University of California, Berkeley","Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"California Institute for Quantitative Biosciences, University of California, Berkeley","institution_ids":["https://openalex.org/I103922791","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Chemistry, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I95457486"]},{"raw_affiliation_string":"Department of Physics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Jason L Choy Laboratory of Single Molecule Biophysics, University of California, Berkeley","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ribosome","display_name":"ribosome","score":0.8109999895095825},{"id":"https://openalex.org/keywords/mrna-translocation","display_name":"mRNA translocation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/mechanical-work","display_name":"mechanical work","score":0.8040000200271606},{"id":"https://openalex.org/keywords/optical-tweezers","display_name":"optical tweezers","score":0.8709999918937683},{"id":"https://openalex.org/keywords/single-molecule-force-measurement","display_name":"single-molecule force measurement","score":0.6179999709129333},{"id":"https://openalex.org/keywords/translation-rate","display_name":"translation rate","score":0.8360000252723694},{"id":"https://openalex.org/keywords/brownian-ratchet","display_name":"Brownian ratchet","score":0.9179999828338623}],"concepts":[{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.7939910292625427},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.6208977699279785},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.576653003692627},{"id":"https://openalex.org/C10853874","wikidata":"https://www.wikidata.org/wiki/Q180618","display_name":"Genetic code","level":3,"score":0.45396149158477783},{"id":"https://openalex.org/C3675279","wikidata":"https://www.wikidata.org/wiki/Q211935","display_name":"Protein biosynthesis","level":2,"score":0.42942869663238525},{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.4170013666152954},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.4027068018913269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38003069162368774},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3572271764278412},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.343780517578125},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3076598048210144},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.3038027882575989},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2484588623046875}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.03406.010","doi":"https://doi.org/10.7554/elife.03406.010","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.03406.010","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"}],"best_oa_location":{"id":"doi:10.7554/elife.03406.010","doi":"https://doi.org/10.7554/elife.03406.010","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.03406.010","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2160371877","https://openalex.org/W2463294007","https://openalex.org/W1965588440","https://openalex.org/W99909373","https://openalex.org/W4294577699","https://openalex.org/W3160971404","https://openalex.org/W1988097982","https://openalex.org/W2060096574","https://openalex.org/W2025842415","https://openalex.org/W2593566059"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2019-11-22T00:00:00"}