{"id":"https://openalex.org/W2987783230","doi":"https://doi.org/10.1038/s41559-019-1015-y","title":"Promotion of protocell self-assembly from mixed amphiphiles at the origin of life","display_name":"Promotion of protocell self-assembly from mixed amphiphiles at the origin of life","publication_year":2019,"publication_date":"2019-11-04","ids":{"openalex":"https://openalex.org/W2987783230","doi":"https://doi.org/10.1038/s41559-019-1015-y","mag":"2987783230","pmid":"https://pubmed.ncbi.nlm.nih.gov/31686020"},"language":"en","primary_location":{"id":"doi:10.1038/s41559-019-1015-y","doi":"https://doi.org/10.1038/s41559-019-1015-y","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41559-019-1015-y","pdf_url":null,"source":{"id":"https://openalex.org/S2764884935","display_name":"Nature Ecology & Evolution","issn_l":"2397-334X","issn":["2397-334X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Ecology & Evolution","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003652235","display_name":"Se\u00e1n F. Jordan","orcid":"https://orcid.org/0000-0001-8403-1100","observed_orcids":["https://orcid.org/0000-0001-8403-1100"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sean F. Jordan","raw_affiliation_strings":["Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0001-8403-1100","affiliations":[{"raw_affiliation_string":"Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070987833","display_name":"Hanadi Rammu","orcid":"https://orcid.org/0000-0002-9597-5059","observed_orcids":["https://orcid.org/0000-0002-9597-5059"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hanadi Rammu","raw_affiliation_strings":["Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075814212","display_name":"Ivan N. Zheludev","orcid":"https://orcid.org/0000-0002-9572-0574","observed_orcids":["https://orcid.org/0000-0002-9572-0574"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ivan N. Zheludev","raw_affiliation_strings":["Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088323430","display_name":"Andrew M. Hartley","orcid":"https://orcid.org/0000-0001-7986-6736","observed_orcids":["https://orcid.org/0000-0001-7986-6736"]},"institutions":[{"id":"https://openalex.org/I4210157240","display_name":"Institute of Structural and Molecular Biology","ror":"https://ror.org/05wsetc54","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210157240","https://openalex.org/I45129253","https://openalex.org/I98259816"]},{"id":"https://openalex.org/I98259816","display_name":"Birkbeck, University of London","ror":"https://ror.org/02mb95055","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I98259816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew M. Hartley","raw_affiliation_strings":["Institute of Structural and Molecular Biology, Birkbeck College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Structural and Molecular Biology, Birkbeck College, London, UK","institution_ids":["https://openalex.org/I4210157240","https://openalex.org/I98259816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039327431","display_name":"Amandine Mar\u00e9chal","orcid":"https://orcid.org/0000-0003-3460-3806","observed_orcids":["https://orcid.org/0000-0003-3460-3806"]},"institutions":[{"id":"https://openalex.org/I4210157240","display_name":"Institute of Structural and Molecular Biology","ror":"https://ror.org/05wsetc54","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210157240","https://openalex.org/I45129253","https://openalex.org/I98259816"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I98259816","display_name":"Birkbeck, University of London","ror":"https://ror.org/02mb95055","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I98259816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Amandine Mar\u00e9chal","raw_affiliation_strings":["Institute of Structural and Molecular Biology, Birkbeck College, London, UK","Institute of Structural and Molecular Biology, University College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0003-3460-3806","affiliations":[{"raw_affiliation_string":"Institute of Structural and Molecular Biology, Birkbeck College, London, UK","institution_ids":["https://openalex.org/I4210157240","https://openalex.org/I98259816"]},{"raw_affiliation_string":"Institute of Structural and Molecular Biology, University College London, London, UK","institution_ids":["https://openalex.org/I4210157240","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044237240","display_name":"Nick J. Lane","orcid":"https://orcid.org/0000-0002-5433-3973","observed_orcids":["https://orcid.org/0000-0002-5433-3973"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nick Lane","raw_affiliation_strings":["Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK. nick.lane@ucl.ac.uk","Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0002-5433-3973","affiliations":[{"raw_affiliation_string":"Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK. nick.lane@ucl.ac.uk","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, UK","institution_ids":["https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044237240"],"corresponding_institution_ids":["https://openalex.org/I45129253"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":8.4488,"has_fulltext":false,"cited_by_count":181,"citation_normalized_percentile":{"value":0.98591795,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"3","issue":"12","first_page":"1705","last_page":"1714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/origin-of-life","display_name":"origin of life","score":0.9620000123977661},{"id":"https://openalex.org/keywords/protocells","display_name":"protocells","score":0.9279999732971191},{"id":"https://openalex.org/keywords/vesicle-self-assembly","display_name":"vesicle self-assembly","score":0.9229999780654907},{"id":"https://openalex.org/keywords/single-chain-amphiphiles","display_name":"single-chain amphiphiles","score":0.9610000252723694},{"id":"https://openalex.org/keywords/fatty-acids","display_name":"fatty acids","score":0.8989999890327454},{"id":"https://openalex.org/keywords/fischer-tropsch-synthesis","display_name":"Fischer-Tropsch synthesis","score":0.890999972820282},{"id":"https://openalex.org/keywords/hydrothermal-vents","display_name":"hydrothermal vents","score":0.7009999752044678},{"id":"https://openalex.org/keywords/1-alkanols","display_name":"1-alkanols","score":0.8180000185966492},{"id":"https://openalex.org/keywords/terpenoids","display_name":"terpenoids","score":0.9319999814033508},{"id":"https://openalex.org/keywords/vesicle-stability","display_name":"vesicle stability","score":0.8190000057220459},{"id":"https://openalex.org/keywords/ph-tolerance","display_name":"pH tolerance","score":0.3580000102519989},{"id":"https://openalex.org/keywords/salinity","display_name":"salinity","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C114032466","wikidata":"https://www.wikidata.org/wiki/Q1389465","display_name":"Protocell","level":3,"score":0.9390099048614502},{"id":"https://openalex.org/C98147612","wikidata":"https://www.wikidata.org/wiki/Q215599","display_name":"Promotion (chess)","level":3,"score":0.6459905505180359},{"id":"https://openalex.org/C67407626","wikidata":"https://www.wikidata.org/wiki/Q5723218","display_name":"Amphiphile","level":4,"score":0.5955568552017212},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30911433696746826},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.10775992274284363},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10136067867279053},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.05574733018875122},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012623","descriptor_name":"Seawater","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058045","descriptor_name":"Artificial Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41559-019-1015-y","doi":"https://doi.org/10.1038/s41559-019-1015-y","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41559-019-1015-y","pdf_url":null,"source":{"id":"https://openalex.org/S2764884935","display_name":"Nature Ecology & Evolution","issn_l":"2397-334X","issn":["2397-334X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Ecology & Evolution","raw_type":"journal-article"},{"id":"pmid:31686020","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31686020","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature ecology & evolution","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.bbk.ac.uk.oai2:29841","doi":null,"is_oa":false,"landing_page_url":"https://eprints.bbk.ac.uk/id/eprint/29841/1/Jordan%20Lane%20Nat%20Ecol%20Evol%20accepted%20MS%202019.pdf","pdf_url":"https://eprints.bbk.ac.uk/id/eprint/29841/1/Jordan%20Lane%20Nat%20Ecol%20Evol%20accepted%20MS%202019.pdf","source":{"id":"https://openalex.org/S4306400465","display_name":"BIROn (Birkbeck, University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98259816","host_organization_name":"Birkbeck, University of London","host_organization_lineage":["https://openalex.org/I98259816"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10085211","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10085211/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Ecology & Evolution , 3 pp. 1705-1714. (2019)","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4350707255","display_name":"Growth and heredity of protocells at the origin of life under simulated hydrothermal conditions","funder_award_id":"2089390","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G5692429568","display_name":"Cytochrome c oxidase: structure, function and malfunction","funder_award_id":"MR/M00936X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320320240","display_name":"Research Councils UK","ror":"https://ror.org/00dq2kk65"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W1489938111","https://openalex.org/W1495374002","https://openalex.org/W1522131988","https://openalex.org/W1576811559","https://openalex.org/W1631795182","https://openalex.org/W1638884317","https://openalex.org/W1865861785","https://openalex.org/W1965932773","https://openalex.org/W1982264153","https://openalex.org/W1992031516","https://openalex.org/W1993130196","https://openalex.org/W1994097939","https://openalex.org/W2009680818","https://openalex.org/W2010659277","https://openalex.org/W2015506896","https://openalex.org/W2025579355","https://openalex.org/W2031532282","https://openalex.org/W2033636230","https://openalex.org/W2035339467","https://openalex.org/W2036896125","https://openalex.org/W2037358249","https://openalex.org/W2039027370","https://openalex.org/W2049683776","https://openalex.org/W2050285934","https://openalex.org/W2064855672","https://openalex.org/W2066840832","https://openalex.org/W2068934337","https://openalex.org/W2073934614","https://openalex.org/W2076968073","https://openalex.org/W2078637473","https://openalex.org/W2078913058","https://openalex.org/W2081345082","https://openalex.org/W2089644153","https://openalex.org/W2090887754","https://openalex.org/W2092402179","https://openalex.org/W2092943460","https://openalex.org/W2102770287","https://openalex.org/W2106509411","https://openalex.org/W2107710538","https://openalex.org/W2116244149","https://openalex.org/W2123612271","https://openalex.org/W2125611981","https://openalex.org/W2130107304","https://openalex.org/W2137343169","https://openalex.org/W2141155219","https://openalex.org/W2145198797","https://openalex.org/W2145601109","https://openalex.org/W2153085358","https://openalex.org/W2156233967","https://openalex.org/W2158033739","https://openalex.org/W2165966788","https://openalex.org/W2171224838","https://openalex.org/W2171945056","https://openalex.org/W2179913100","https://openalex.org/W2267335000","https://openalex.org/W2287313494","https://openalex.org/W2416897034","https://openalex.org/W2465519481","https://openalex.org/W2573268563","https://openalex.org/W2611775510","https://openalex.org/W2766339080","https://openalex.org/W2769922066","https://openalex.org/W2789784701","https://openalex.org/W2793350500","https://openalex.org/W2796284206","https://openalex.org/W2802080829","https://openalex.org/W2900416870","https://openalex.org/W2903074371","https://openalex.org/W2945125387","https://openalex.org/W2981184416","https://openalex.org/W2999518182","https://openalex.org/W4235033012","https://openalex.org/W4253687499","https://openalex.org/W4285719527","https://openalex.org/W6672007157"],"related_works":["https://openalex.org/W3185843397","https://openalex.org/W2775449936","https://openalex.org/W6946620265","https://openalex.org/W2134171083","https://openalex.org/W2769922066","https://openalex.org/W3097103114","https://openalex.org/W4386745030","https://openalex.org/W4385727466","https://openalex.org/W4400871266","https://openalex.org/W2287313494"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":30},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":25},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-11-22T00:00:00"}