{"id":"https://openalex.org/W2987228570","doi":null,"title":"Monitoring multiple myeloma.","display_name":"Monitoring multiple myeloma.","publication_year":2017,"publication_date":"2017-12-01","ids":{"openalex":"https://openalex.org/W2987228570","mag":"2987228570","pmid":"https://pubmed.ncbi.nlm.nih.gov/29315287"},"language":"en","primary_location":{"id":"pmid:29315287","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29315287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical advances in hematology & oncology : H&O","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044039905","display_name":"Kyle A. Udd","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151813","display_name":"Institute for Myeloma & Bone Cancer Research","ror":"https://ror.org/04xwmf991","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210151813"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyle A Udd","raw_affiliation_strings":["Institute for Myeloma and Bone Cancer Research, West Hollywood, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Myeloma and Bone Cancer Research, West Hollywood, California","institution_ids":["https://openalex.org/I4210151813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068437316","display_name":"Tanya Magazinnik Spektor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111451","display_name":"Oncotherapeutics (United States)","ror":"https://ror.org/01s33dn56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210111451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanya M Spektor","raw_affiliation_strings":["Oncotherapeutics, West Hollywood, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oncotherapeutics, West Hollywood, California","institution_ids":["https://openalex.org/I4210111451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040835019","display_name":"James R. Berenson","orcid":"https://orcid.org/0000-0003-1587-6104","observed_orcids":["https://orcid.org/0000-0003-1587-6104"]},"institutions":[{"id":"https://openalex.org/I4210111451","display_name":"Oncotherapeutics (United States)","ror":"https://ror.org/01s33dn56","country_code":"US","type":"company","lineage":["https://openalex.org/I4210111451"]},{"id":"https://openalex.org/I4210151813","display_name":"Institute for Myeloma & Bone Cancer Research","ror":"https://ror.org/04xwmf991","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210151813"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R Berenson","raw_affiliation_strings":["Institute for Myeloma and Bone Cancer Research, West Hollywood, California","Oncotherapeutics, West Hollywood, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Myeloma and Bone Cancer Research, West Hollywood, California","institution_ids":["https://openalex.org/I4210151813"]},{"raw_affiliation_string":"Oncotherapeutics, West Hollywood, California","institution_ids":["https://openalex.org/I4210111451"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2064,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.52176664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"15","issue":"12","first_page":"951","last_page":"961"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":1.0},{"id":"https://openalex.org/keywords/disease-surveillance","display_name":"disease surveillance","score":0.9539999961853027},{"id":"https://openalex.org/keywords/treatment-response-assessment","display_name":"treatment response assessment","score":0.7829999923706055},{"id":"https://openalex.org/keywords/monoclonal-paraprotein","display_name":"monoclonal paraprotein","score":0.9129999876022339},{"id":"https://openalex.org/keywords/free-light-chains","display_name":"free light chains","score":0.9079999923706055},{"id":"https://openalex.org/keywords/b-cell-maturation-antigen","display_name":"BCMA","score":0.9900000095367432},{"id":"https://openalex.org/keywords/positron-emission-tomography-computed-tomography","display_name":"positron emission tomography/computed tomography","score":0.9409999847412109},{"id":"https://openalex.org/keywords/bone-marrow-examination","display_name":"bone marrow examination","score":0.972000002861023},{"id":"https://openalex.org/keywords/tumor-burden","display_name":"tumor burden","score":0.7179999947547913},{"id":"https://openalex.org/keywords/plasma-cell-malignancy","display_name":"plasma cell malignancy","score":0.5659999847412109}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9633389115333557},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.8309076428413391},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.6561179161071777},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5821340680122375},{"id":"https://openalex.org/C2909984355","wikidata":"https://www.wikidata.org/wiki/Q2509220","display_name":"Hematologic malignancy","level":2,"score":0.5220051407814026},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4890194833278656},{"id":"https://openalex.org/C2776396001","wikidata":"https://www.wikidata.org/wiki/Q250694","display_name":"Plasma cell","level":3,"score":0.47227346897125244},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.44048431515693665},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4291859269142151},{"id":"https://openalex.org/C163864487","wikidata":"https://www.wikidata.org/wiki/Q6901461","display_name":"Monoclonal","level":4,"score":0.41692879796028137},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.39860236644744873},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3760288655757904},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.34375035762786865},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.24863505363464355},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.17274758219718933},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.15972855687141418}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:29315287","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29315287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical advances in hematology & oncology : H&O","raw_type":"Journal Article"},{"id":"mag:2987228570","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29315287","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":86,"referenced_works":["https://openalex.org/W18131798","https://openalex.org/W54494683","https://openalex.org/W64395884","https://openalex.org/W1492394546","https://openalex.org/W1534557867","https://openalex.org/W1535201509","https://openalex.org/W1591151205","https://openalex.org/W1661103064","https://openalex.org/W1706760553","https://openalex.org/W1853807720","https://openalex.org/W1903239767","https://openalex.org/W1955975006","https://openalex.org/W1970864109","https://openalex.org/W1976195576","https://openalex.org/W1979216455","https://openalex.org/W1984259729","https://openalex.org/W1985012922","https://openalex.org/W1985021407","https://openalex.org/W1990835696","https://openalex.org/W1996100864","https://openalex.org/W2002048624","https://openalex.org/W2006382315","https://openalex.org/W2006393030","https://openalex.org/W2006916642","https://openalex.org/W2008182609","https://openalex.org/W2013296669","https://openalex.org/W2018943586","https://openalex.org/W2020298011","https://openalex.org/W2020519329","https://openalex.org/W2025013606","https://openalex.org/W2031314023","https://openalex.org/W2043514329","https://openalex.org/W2046408556","https://openalex.org/W2047739508","https://openalex.org/W2050314073","https://openalex.org/W2052978273","https://openalex.org/W2056442040","https://openalex.org/W2060076496","https://openalex.org/W2063208192","https://openalex.org/W2068076832","https://openalex.org/W2072711146","https://openalex.org/W2079278201","https://openalex.org/W2080218360","https://openalex.org/W2085871891","https://openalex.org/W2086595383","https://openalex.org/W2086768501","https://openalex.org/W2087843841","https://openalex.org/W2091228530","https://openalex.org/W2092875330","https://openalex.org/W2097147259","https://openalex.org/W2118468335","https://openalex.org/W2120474651","https://openalex.org/W2124240218","https://openalex.org/W2128192762","https://openalex.org/W2132155854","https://openalex.org/W2144588669","https://openalex.org/W2144728882","https://openalex.org/W2146909892","https://openalex.org/W2157513488","https://openalex.org/W2159528874","https://openalex.org/W2165869640","https://openalex.org/W2167892065","https://openalex.org/W2168018375","https://openalex.org/W2168073366","https://openalex.org/W2208728563","https://openalex.org/W2285922762","https://openalex.org/W2300006655","https://openalex.org/W2345005763","https://openalex.org/W2352014362","https://openalex.org/W2414837378","https://openalex.org/W2463972652","https://openalex.org/W2486629951","https://openalex.org/W2500224976","https://openalex.org/W2531573595","https://openalex.org/W2549408839","https://openalex.org/W2556802956","https://openalex.org/W2562243521","https://openalex.org/W2579739608","https://openalex.org/W2586624477","https://openalex.org/W2587921568","https://openalex.org/W2589691843","https://openalex.org/W2605874853","https://openalex.org/W2609949358","https://openalex.org/W2724736336","https://openalex.org/W4238153906","https://openalex.org/W4312861613"],"related_works":["https://openalex.org/W4386305229","https://openalex.org/W4297253401","https://openalex.org/W4386086917","https://openalex.org/W2595092380","https://openalex.org/W6926592972","https://openalex.org/W4367319448","https://openalex.org/W2016998727","https://openalex.org/W2980399421","https://openalex.org/W4406428343","https://openalex.org/W4378349408"],"abstract_inverted_index":{"Multiple":[0],"myeloma":[1],"(MM)":[2],"is":[3,20,63],"a":[4,21,34],"B-cell":[5,108],"malignancy":[6],"characterized":[7],"by":[8],"the":[9,56,69,100,150,154],"accumulation":[10],"in":[11,55,181,184,190],"bone":[12],"marrow":[13,143],"of":[14,37,53,59,68,72,90,106,153,169],"terminally":[15],"differentiated":[16],"plasma":[17],"cells.":[18],"MM":[19,32,62,85,187],"slowly":[22],"growing,":[23],"heterogeneous":[24,151],"disease":[25,155],"with":[26,31,61,84,121,165,186],"no":[27],"known":[28],"cure.":[29],"Patients":[30],"have":[33,102],"median":[35],"survival":[36],"approximately":[38],"5":[39],"years,":[40],"during":[41],"which":[42],"they":[43],"may":[44,112],"experience":[45],"significant":[46],"morbidity.":[47],"More":[48],"reliable":[49],"and":[50,93,116,140,172,177],"rapid":[51],"determination":[52],"changes":[54,180],"clinical":[57],"status":[58],"patients":[60,83,120,164,185],"becoming":[64],"increasingly":[65],"important":[66],"because":[67],"increasing":[70],"number":[71],"available":[73,79],"treatments":[74],"for":[75,81,119,193],"these":[76,114,194],"patients.":[77,195],"Currently":[78],"tests":[80,101],"monitoring":[82],"most":[86],"often":[87],"include":[88],"assessments":[89],"monoclonal":[91],"paraprotein":[92],"serum":[94,107],"free":[95],"light":[96],"chain":[97],"levels,":[98],"but":[99,137,149],"several":[103],"limitations.":[104],"Measurement":[105],"maturation":[109],"antigen":[110],"level":[111],"overcome":[113],"limitations":[115],"improve":[117],"outcomes":[118,192],"MM.":[122,166],"Newer":[123],"radiologic":[124],"procedures":[125],"such":[126],"as":[127],"positron":[128],"emission":[129],"tomography/computed":[130],"tomography":[131],"are":[132,138],"superior":[133],"to":[134,159,162,174],"plain":[135],"radiographs,":[136],"costly":[139],"inconvenient.":[141],"Bone":[142],"examination":[144],"directly":[145],"identifies":[146],"malignant":[147],"cells,":[148],"nature":[152],"makes":[156],"it":[157],"problematic":[158],"use":[160],"routinely":[161],"follow":[163],"The":[167],"development":[168],"new":[170],"markers":[171],"approaches":[173],"more":[175],"accurately":[176],"quickly":[178],"assess":[179],"tumor":[182],"burden":[183],"should":[188],"result":[189],"better":[191]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-11-22T00:00:00"}