{"id":"https://openalex.org/W2980977120","doi":null,"title":"Comprehensive analysis of long non-coding RNA PVT1 gene interaction regulatory network in hepatocellular carcinoma using gene microarray and bioinformatics.","display_name":"Comprehensive analysis of long non-coding RNA PVT1 gene interaction regulatory network in hepatocellular carcinoma using gene microarray and bioinformatics.","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2980977120","mag":"2980977120","pmid":"https://pubmed.ncbi.nlm.nih.gov/28979669","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5622238"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:4551068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5622238","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5622238","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100433732","display_name":"Yu Zhang","orcid":"https://orcid.org/0000-0003-3474-422X","observed_orcids":["https://orcid.org/0000-0003-3474-422X","https://orcid.org/0000-0003-0349-7393"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Zhang","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103062437","display_name":"Yiwu Dang","orcid":"https://orcid.org/0000-0002-3026-2429","observed_orcids":["https://orcid.org/0000-0002-3026-2429"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi-Wu Dang","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100411447","display_name":"Xiao Wang","orcid":"https://orcid.org/0000-0002-0077-7341","observed_orcids":["https://orcid.org/0000-0002-0077-7341"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210116517","display_name":"Shandong Provincial Hospital","ror":"https://ror.org/02ar2nf05","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Wang","raw_affiliation_strings":["Department of Orthopedics, Shandong Provincial Hospital Affiliated to Shandong UniversityJinan 250012, Shandong Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Shandong Provincial Hospital Affiliated to Shandong UniversityJinan 250012, Shandong Province, China","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210116517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101535144","display_name":"Xia Yang","orcid":"https://orcid.org/0000-0003-1757-1355","observed_orcids":["https://orcid.org/0000-0003-1757-1355"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xia Yang","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100421935","display_name":"Rui Zhang","orcid":"https://orcid.org/0000-0001-5854-2468","observed_orcids":["https://orcid.org/0000-0001-5854-2468"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Zhang","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112119410","display_name":"Zili Lv","orcid":"https://orcid.org/0000-0001-9553-781X","observed_orcids":["https://orcid.org/0000-0001-9553-781X"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zi-Li Lv","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100389268","display_name":"Gang Chen","orcid":"https://orcid.org/0000-0002-4864-1451","observed_orcids":["https://orcid.org/0000-0002-4864-1451","https://orcid.org/0000-0003-2402-2987","https://orcid.org/0000-0002-8105-2384"]},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Chen","raw_affiliation_strings":["Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, First Affiliated Hospital of Guangxi Medical University6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China","institution_ids":["https://openalex.org/I4210126060"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4049,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.89352161,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9","issue":"9","first_page":"3904","last_page":"3917"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pvt1","display_name":"PVT1","score":0.9419999718666077},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dlc1","display_name":"DLC1","score":0.996999979019165},{"id":"https://openalex.org/keywords/hippo-signaling-pathway","display_name":"Hippo signaling pathway","score":0.8379999995231628},{"id":"https://openalex.org/keywords/gene-regulatory-networks","display_name":"gene regulatory networks","score":0.8379999995231628},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.7990000247955322},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8289999961853027},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.4059999883174896},{"id":"https://openalex.org/keywords/vascular-invasion","display_name":"vascular invasion","score":0.6169999837875366},{"id":"https://openalex.org/keywords/tumor-grade","display_name":"tumor grade","score":0.921999990940094}],"concepts":[{"id":"https://openalex.org/C2777394393","wikidata":"https://www.wikidata.org/wiki/Q18030968","display_name":"PVT1","level":5,"score":0.9115060567855835},{"id":"https://openalex.org/C152724338","wikidata":"https://www.wikidata.org/wiki/Q909442","display_name":"KEGG","level":5,"score":0.7967677712440491},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6614762544631958},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6181789040565491},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.502392053604126},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.49935221672058105},{"id":"https://openalex.org/C62203573","wikidata":"https://www.wikidata.org/wiki/Q15087973","display_name":"Long non-coding RNA","level":4,"score":0.4915352761745453},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.46288415789604187},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.4513702094554901},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.44047585129737854},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.42429083585739136},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3746519386768341},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3450005352497101},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3207889199256897},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.2528253495693207},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.2103196084499359}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:4551068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5622238","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:28979669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28979669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5622238","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5622238/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},{"id":"mag:2980977120","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28979669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4551068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5622238","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8999999761581421}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W133741797","https://openalex.org/W214448376","https://openalex.org/W563719155","https://openalex.org/W746630715","https://openalex.org/W1629166275","https://openalex.org/W1970741980","https://openalex.org/W1995504478","https://openalex.org/W2003997978","https://openalex.org/W2012273224","https://openalex.org/W2016722143","https://openalex.org/W2056910975","https://openalex.org/W2082668371","https://openalex.org/W2088924273","https://openalex.org/W2091161969","https://openalex.org/W2094407945","https://openalex.org/W2100967414","https://openalex.org/W2103017472","https://openalex.org/W2126504590","https://openalex.org/W2143785235","https://openalex.org/W2152369601","https://openalex.org/W2163265140","https://openalex.org/W2165474729","https://openalex.org/W2167198607","https://openalex.org/W2250182730","https://openalex.org/W2259432811","https://openalex.org/W2260312833","https://openalex.org/W2269199783","https://openalex.org/W2341774243","https://openalex.org/W2417073627","https://openalex.org/W2497522895","https://openalex.org/W2509610924","https://openalex.org/W2531066839","https://openalex.org/W2532643640","https://openalex.org/W2542690450","https://openalex.org/W2554761876","https://openalex.org/W2558036593","https://openalex.org/W2558639270","https://openalex.org/W2559569254","https://openalex.org/W2569647861","https://openalex.org/W2589036102","https://openalex.org/W2590032828","https://openalex.org/W2591715383","https://openalex.org/W2591863070","https://openalex.org/W2592407340","https://openalex.org/W2593480532","https://openalex.org/W2594337384","https://openalex.org/W2595139975","https://openalex.org/W2595268158","https://openalex.org/W2597262730","https://openalex.org/W2598907887","https://openalex.org/W2601298138","https://openalex.org/W2604381713","https://openalex.org/W2917837889"],"related_works":["https://openalex.org/W2799434578","https://openalex.org/W2833506229","https://openalex.org/W2745282358","https://openalex.org/W2100967414","https://openalex.org/W2983829641","https://openalex.org/W3129025031","https://openalex.org/W3008255149","https://openalex.org/W2799960940","https://openalex.org/W3122440071","https://openalex.org/W2831618164"],"abstract_inverted_index":{"PVT1":[0,19,41,51,68,113,124,147,168,180],"has":[1,135],"been":[2,136],"reported":[3],"to":[4,34,91],"be":[5,209],"involved":[6],"in":[7,20,53,117,130,139,159,175,186],"the":[8,16,93,110,162,201],"tumorigenesis":[9],"and":[10,44,49,64,85,88,96,156,169,189,196,200],"development":[11,188],"of":[12,18,83,98,146,193],"different":[13,140],"cancers.":[14],"However,":[15,205],"role":[17,185],"hepatocellular":[21],"carcinoma":[22],"(HCC)":[23],"remains":[24],"unclear.":[25],"In":[26],"this":[27,206],"study,":[28],"we":[29],"applied":[30],"gene":[31],"microarray":[32],"analysis":[33],"detect":[35],"differentially":[36],"expressed":[37],"genes":[38,63],"(DEGs)":[39],"between":[40],"RNAi":[42],"groups":[43],"controls.":[45],"We":[46,72,102,177],"initially":[47],"investigated":[48],"confirmed":[50,210],"expression":[52,125,145],"HCC":[54,187],"using":[55],"The":[56,61],"Cancer":[57],"Genome":[58],"Atlas":[59],"(TCGA).":[60],"potential":[62,100],"pathways":[65,95,195],"associated":[66,150],"with":[67,128,142,151],"were":[69],"also":[70,73],"analyzed.":[71],"performed":[74],"bioinformatics":[75],"analyses":[76],"(Gene":[77],"Ontology":[78],"(GO),":[79],"pathway,":[80],"Kyoto":[81],"Encyclopedia":[82],"Genes":[84],"Genomes":[86],"(KEGG),":[87],"network":[89],"analyses)":[90],"explore":[92],"underlying":[94],"networks":[97],"these":[99],"genes.":[101],"selected":[103],"DLC1":[104,120,129,170,199],"for":[105],"further":[106,137],"analysis.":[107],"Based":[108],"on":[109],"TCGA":[111],"database,":[112],"was":[114,121,148],"markedly":[115],"up-regulated":[116],"HCC,":[118,131],"whereas":[119],"down-regulated.":[122],"Moreover,":[123],"negatively":[126],"correlated":[127],"an":[132],"observation":[133],"that":[134,166,179],"validated":[138],"cohorts":[141],"Oncomine.":[143],"High":[144],"positively":[149],"gender,":[152],"race,":[153],"vascular":[154],"invasion":[155],"pathological":[157],"grade":[158],"HCC.":[160,176],"Additionally,":[161],"ROC":[163],"curve":[164],"indicated":[165],"both":[167],"have":[171],"high":[172],"diagnostic":[173],"value":[174],"speculated":[178],"might":[181],"play":[182],"a":[183],"significant":[184],"progression":[190],"via":[191],"regulation":[192],"various":[194],"genes,":[197],"especially":[198],"Hippo":[202],"signaling":[203],"pathway.":[204],"mechanism":[207],"should":[208],"by":[211],"functional":[212],"experiments.":[213]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":11}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-10-25T00:00:00"}
