{"id":"https://openalex.org/W2980880396","doi":"https://doi.org/10.7518/hxkq.2017.05.017","title":"[Clinical applications of stem cells from human exfoliated deciduous teeth in stem cell therapy].","display_name":"[Clinical applications of stem cells from human exfoliated deciduous teeth in stem cell therapy].","publication_year":2017,"publication_date":"2017-10-01","ids":{"openalex":"https://openalex.org/W2980880396","doi":"https://doi.org/10.7518/hxkq.2017.05.017","mag":"2980880396","pmid":"https://pubmed.ncbi.nlm.nih.gov/29188652","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7030391"},"language":"zh","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7030391","doi":"https://doi.org/10.7518/hxkq.2017.05.017","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7030391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hua Xi Kou Qiang Yi Xue Za Zhi","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7030391","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100348756","display_name":"Xiaoxia Li","orcid":"https://orcid.org/0000-0002-4872-9525","observed_orcids":["https://orcid.org/0000-0002-4872-9525"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210095659","display_name":"Peking University School and Hospital of Stomatology","ror":"https://ror.org/00s2xkh70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095659"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Xiaoxia","raw_affiliation_strings":["Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210095659"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Fangteng Jiaozi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210095659","display_name":"Peking University School and Hospital of Stomatology","ror":"https://ror.org/00s2xkh70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095659"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fangteng Jiaozi","raw_affiliation_strings":["Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210095659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114111337","display_name":"Yu Shi","orcid":"https://orcid.org/0009-0005-5749-515X","observed_orcids":["https://orcid.org/0009-0005-5749-515X"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210095659","display_name":"Peking University School and Hospital of Stomatology","ror":"https://ror.org/00s2xkh70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095659"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Shi","raw_affiliation_strings":["Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210095659"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhao Yuming","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210095659","display_name":"Peking University School and Hospital of Stomatology","ror":"https://ror.org/00s2xkh70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095659"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Yuming","raw_affiliation_strings":["Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210095659"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112481905","display_name":"GE Lihong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210095659","display_name":"Peking University School and Hospital of Stomatology","ror":"https://ror.org/00s2xkh70","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210095659"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ge Lihong","raw_affiliation_strings":["Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210095659"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1562,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.55364693,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"35","issue":"5","first_page":"533","last_page":"537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stem-cells-from-human-exfoliated-deciduous-teeth","display_name":"stem cells from human exfoliated deciduous teeth","score":0.9279999732971191},{"id":"https://openalex.org/keywords/dental-stem-cells","display_name":"dental stem cells","score":0.9240000247955322},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.902999997138977},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.8930000066757202},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.9049999713897705},{"id":"https://openalex.org/keywords/multilineage-differentiation","display_name":"multilineage differentiation","score":0.8370000123977661},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.972000002861023},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/dentin-pulp-regeneration","display_name":"dentin-pulp regeneration","score":0.9829999804496765},{"id":"https://openalex.org/keywords/maxillofacial-bone-regeneration","display_name":"maxillofacial bone regeneration","score":0.9919999837875366},{"id":"https://openalex.org/keywords/neurological-disorders","display_name":"neurological disorders","score":0.8240000009536743},{"id":"https://openalex.org/keywords/immune-system-diseases","display_name":"immune system diseases","score":0.9629999995231628},{"id":"https://openalex.org/keywords/stem-cell-transplantation","display_name":"stem cell transplantation","score":0.9039999842643738}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.8680688142776489},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6755838394165039},{"id":"https://openalex.org/C2779389132","wikidata":"https://www.wikidata.org/wiki/Q1533033","display_name":"Stem-cell therapy","level":3,"score":0.6556762456893921},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6376431584358215},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5589630603790283},{"id":"https://openalex.org/C2776981409","wikidata":"https://www.wikidata.org/wiki/Q281524","display_name":"Deciduous teeth","level":2,"score":0.4913095533847809},{"id":"https://openalex.org/C2777400515","wikidata":"https://www.wikidata.org/wiki/Q5259430","display_name":"Dental pulp stem cells","level":3,"score":0.475119411945343},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.4587472081184387},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.448763370513916},{"id":"https://openalex.org/C143441281","wikidata":"https://www.wikidata.org/wiki/Q5133858","display_name":"Clinical uses of mesenchymal stem cells","level":5,"score":0.4201813340187073},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.41078582406044006},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.31612470746040344},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.28953760862350464},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2709673047065735},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.2387295365333557},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0997610092163086},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003782","descriptor_name":"Dental Pulp","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014094","descriptor_name":"Tooth, Deciduous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:7030391","doi":"https://doi.org/10.7518/hxkq.2017.05.017","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7030391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hua Xi Kou Qiang Yi Xue Za Zhi","raw_type":"Text"},{"id":"pmid:29188652","doi":"https://doi.org/10.7518/hxkq.2017.05.017","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29188652","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","raw_type":"Journal Article"},{"id":"mag:2980880396","doi":"https://doi.org/10.7518/hxkq.2017.05.017","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29188652","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7030391","doi":"https://doi.org/10.7518/hxkq.2017.05.017","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7030391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hua Xi Kou Qiang Yi Xue Za Zhi","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1837964383","https://openalex.org/W1846124105","https://openalex.org/W1892832444","https://openalex.org/W1919100089","https://openalex.org/W1956428707","https://openalex.org/W1972478740","https://openalex.org/W1972487833","https://openalex.org/W1988477032","https://openalex.org/W1988830115","https://openalex.org/W1990552399","https://openalex.org/W2000041431","https://openalex.org/W2018258390","https://openalex.org/W2024326908","https://openalex.org/W2025093153","https://openalex.org/W2026989391","https://openalex.org/W2036550391","https://openalex.org/W2043396063","https://openalex.org/W2045183077","https://openalex.org/W2056274924","https://openalex.org/W2060677906","https://openalex.org/W2080137511","https://openalex.org/W2088344769","https://openalex.org/W2095544691","https://openalex.org/W2102069687","https://openalex.org/W2113148633","https://openalex.org/W2115437022","https://openalex.org/W2116316981","https://openalex.org/W2116864112","https://openalex.org/W2121776449","https://openalex.org/W2122032578","https://openalex.org/W2152938273","https://openalex.org/W2154330374","https://openalex.org/W2156895150","https://openalex.org/W2166364433","https://openalex.org/W2171537081","https://openalex.org/W2235702117","https://openalex.org/W2261291129","https://openalex.org/W2264005066","https://openalex.org/W2326908954","https://openalex.org/W2337598380"],"related_works":["https://openalex.org/W3082908857","https://openalex.org/W4401276200","https://openalex.org/W4400515548","https://openalex.org/W3138614684","https://openalex.org/W3003901264","https://openalex.org/W3195595850","https://openalex.org/W4212891358","https://openalex.org/W3120750924","https://openalex.org/W6903626287","https://openalex.org/W2116864112"],"abstract_inverted_index":{"Stem":[0],"cells":[1],"from":[2],"human":[3],"exfoliated":[4],"deciduous":[5],"teeth":[6],"(SHED)":[7],"are":[8],"one":[9],"category":[10],"of":[11,44,66,83,88,103],"dental":[12],"stem":[13,20,25,33,47,113],"cells.":[14,21],"They":[15],"belong":[16],"to":[17,85],"ectodermal":[18],"mesenchymal":[19],"As":[22],"an":[23],"ideal":[24],"cell":[26,34,48,64,114],"source,":[27],"SHED":[28,45,84,111],"possess":[29],"great":[30],"potential":[31,80],"in":[32,46,55,95],"therapy.":[35],"This":[36,90],"review":[37],"demonstrates":[38,92],"the":[39,75,79],"biological":[40],"characteristics":[41],"and":[42,50,58,68,101,106],"advantages":[43],"therapy":[49],"discusses":[51],"its":[52],"multiple":[53,61],"functions":[54],"tissue":[56],"regeneration":[57],"repair,":[59],"including":[60],"differentiation":[62],"potentiality,":[63],"secretion":[65],"cytokines,":[67],"immunomodulatory":[69],"ability.":[70],"Furthermore,":[71],"this":[72],"article":[73,91],"introduces":[74],"main":[76],"findings":[77],"regarding":[78],"clinical":[81],"applications":[82],"a":[86],"variety":[87],"diseases.":[89],"research":[93],"progress":[94],"dentin-pulp":[96],"regeneration,":[97,100],"maxillofacial":[98],"bone":[99],"treatment":[102],"nervous":[104],"system":[105,108],"immune":[107],"diseases":[109],"with":[110],"for":[112],"transplantation.":[115]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2019-10-25T00:00:00"}