{"id":"https://openalex.org/W2980836141","doi":null,"title":"Chemical Meningitis and Status Epilepticus Caused by Accidental Epidural Administration of Digoxin.","display_name":"Chemical Meningitis and Status Epilepticus Caused by Accidental Epidural Administration of Digoxin.","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2980836141","mag":"2980836141","pmid":"https://pubmed.ncbi.nlm.nih.gov/31461586"},"language":"en","primary_location":{"id":"pmid:31461586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31461586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South Dakota medicine : the journal of the South Dakota State Medical Association","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Mohamed A Abdallah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamed A Abdallah","raw_affiliation_strings":["University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017503976","display_name":"Chencheng Xie","orcid":"https://orcid.org/0000-0002-5781-2697","observed_orcids":["https://orcid.org/0000-0002-5781-2697"]},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chencheng Xie","raw_affiliation_strings":["University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023673270","display_name":"Khalid Mohamed Ahmed","orcid":"https://orcid.org/0000-0001-5648-0670","observed_orcids":["https://orcid.org/0000-0001-5648-0670"]},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Khalid Mohamed Ahmed","raw_affiliation_strings":["University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020876185","display_name":"Anthony J. Hericks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114187","display_name":"Avera Heart Hospital","ror":"https://ror.org/0205d0r45","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799572201","https://openalex.org/I4210114187"]},{"id":"https://openalex.org/I4210152391","display_name":"Avera McKennan Hospital & University Health Center","ror":"https://ror.org/04rw83w19","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799572201","https://openalex.org/I4210152391"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony J Hericks","raw_affiliation_strings":["Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota","Avera Heart Hospital, Sioux Falls, South Dakota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota","institution_ids":["https://openalex.org/I4210152391"]},{"raw_affiliation_string":"Avera Heart Hospital, Sioux Falls, South Dakota","institution_ids":["https://openalex.org/I4210114187"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6369,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.67748336,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"72","issue":"7","first_page":"310","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.27390000224113464,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.27390000224113464,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.1200999990105629,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.11490000039339066,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/digoxin","display_name":"digoxin","score":0.7900000214576721},{"id":"https://openalex.org/keywords/intrathecal-administration","display_name":"intrathecal administration","score":0.6850000023841858},{"id":"https://openalex.org/keywords/epidural-anesthesia","display_name":"epidural anesthesia","score":0.6759999990463257},{"id":"https://openalex.org/keywords/accidental-drug-administration","display_name":"accidental drug administration","score":0.7519999742507935},{"id":"https://openalex.org/keywords/chemical-meningitis","display_name":"chemical meningitis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/status-epilepticus","display_name":"status epilepticus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/seizures","display_name":"seizures","score":0.746999979019165},{"id":"https://openalex.org/keywords/cesarean-section","display_name":"cesarean section","score":0.9480000138282776},{"id":"https://openalex.org/keywords/encephalopathy","display_name":"encephalopathy","score":0.6600000262260437},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-analysis","display_name":"cerebrospinal fluid analysis","score":0.6589999794960022},{"id":"https://openalex.org/keywords/anticonvulsant-therapy","display_name":"anticonvulsant therapy","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9186744689941406},{"id":"https://openalex.org/C2777341932","wikidata":"https://www.wikidata.org/wiki/Q980709","display_name":"Status epilepticus","level":3,"score":0.8258793354034424},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.769406795501709},{"id":"https://openalex.org/C2777707475","wikidata":"https://www.wikidata.org/wiki/Q422222","display_name":"Digoxin","level":3,"score":0.7002972364425659},{"id":"https://openalex.org/C2780066322","wikidata":"https://www.wikidata.org/wiki/Q719444","display_name":"Lumbar puncture","level":3,"score":0.5644187927246094},{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.5624091029167175},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.5389031171798706},{"id":"https://openalex.org/C126965237","wikidata":"https://www.wikidata.org/wiki/Q816335","display_name":"Accidental","level":2,"score":0.5147964358329773},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.4408458471298218},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.34434181451797485},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.307786762714386},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.1214158833026886},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0859454870223999},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000767","descriptor_name":"Anesthesia, Epidural","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D002585","descriptor_name":"Cesarean Section","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004077","descriptor_name":"Digoxin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004077","descriptor_name":"Digoxin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008581","descriptor_name":"Meningitis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013226","descriptor_name":"Status Epilepticus","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:31461586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31461586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South Dakota medicine : the journal of the South Dakota State Medical Association","raw_type":"Case Reports"},{"id":"mag:2980836141","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31461586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1964951705","https://openalex.org/W2412991586","https://openalex.org/W4400720454","https://openalex.org/W1975198869","https://openalex.org/W1983709346","https://openalex.org/W2141785404","https://openalex.org/W2048277843","https://openalex.org/W4387823507","https://openalex.org/W2092948047","https://openalex.org/W2081137645"],"abstract_inverted_index":{"Intrathecal":[0],"administration":[1,39],"of":[2,10,28,40,132,145],"digoxin":[3],"occurs":[4],"very":[5],"rarely.":[6],"Some":[7],"case":[8,27],"reports":[9],"inadvertently":[11],"administering":[12],"it":[13],"when":[14],"performing":[15],"spinal/epidural":[16],"anesthesia":[17,47],"were":[18,179],"described.":[19],"We":[20],"report":[21],"for":[22,48,117,124,153],"the":[23,56,96,134,140,168,185],"first":[24],"time":[25],"a":[26,29,49,92,130],"chemical":[30],"meningitis":[31],"and":[32,61,66,84,88,160,162,172,176],"status":[33,89],"epilepticus":[34,90],"caused":[35],"by":[36],"accidental":[37],"epidural":[38,46,147],"digoxin.":[41],"A":[42,106],"26-year-old":[43],"female":[44],"underwent":[45],"planned":[50],"cesarean":[51],"section":[52],"(CS).":[53],"Post":[54],"operatively":[55],"patient":[57,141,150,169],"became":[58,157],"lethargic,":[59],"agitated":[60],"encephalopathic,":[62],"she":[63],"was":[64,82,110,115,121,163,170,182],"intubated":[65,152],"transferred":[67],"to":[68],"our":[69],"hospital":[70,136,186],"intensive":[71],"care":[72],"unit":[73],"(ICU).":[74],"She":[75,156,181],"had":[76],"seizures":[77],"on":[78],"admission.":[79],"Electroencephalogram":[80],"(EEG)":[81],"performed":[83],"showed":[85],"generalized":[86],"slowing":[87],"with":[91],"focus":[93],"noted":[94],"in":[95],"right":[97],"temporal":[98],"region":[99],"which":[100],"resolved":[101],"after":[102,187],"antiepileptic":[103],"medication":[104],"administration.":[105],"lumbar":[107],"puncture":[108],"(LP)":[109],"performed;":[111],"cerebro-spinal":[112],"fluid":[113],"(CSF)":[114],"suggestive":[116],"meningitis.":[118],"However,":[119],"there":[120],"no":[122],"evidence":[123],"viral":[125],"or":[126],"bacterial":[127],"infections.":[128],"Within":[129],"day":[131],"admission,":[133],"referring":[135],"informed":[137],"us":[138],"that":[139],"received":[142],"250":[143],"mcg":[144],"digoxininadvertently-through":[146],"injection.":[148],"The":[149],"remained":[151],"four":[154],"days.":[155,189],"more":[158],"responsive":[159,171],"alert":[161],"eventually":[164],"extubated.":[165],"After":[166],"extubation,":[167],"full":[173],"neurological":[174],"exam":[175],"brain":[177],"imaging":[178],"normal.":[180],"discharged":[183],"from":[184],"seven":[188]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-10-25T00:00:00"}