{"id":"https://openalex.org/W2980729623","doi":"https://doi.org/10.1038/s42255-019-0132-x","title":"Systems genetics applications in metabolism research","display_name":"Systems genetics applications in metabolism research","publication_year":2019,"publication_date":"2019-10-21","ids":{"openalex":"https://openalex.org/W2980729623","doi":"https://doi.org/10.1038/s42255-019-0132-x","mag":"2980729623","pmid":"https://pubmed.ncbi.nlm.nih.gov/32259026","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7111511"},"language":"en","primary_location":{"id":"doi:10.1038/s42255-019-0132-x","doi":"https://doi.org/10.1038/s42255-019-0132-x","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s42255-019-0132-x","pdf_url":null,"source":{"id":"https://openalex.org/S4210232714","display_name":"Nature Metabolism","issn_l":"2522-5812","issn":["2522-5812"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Metabolism","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7111511","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043183177","display_name":"Marcus Michael Seldin","orcid":"https://orcid.org/0000-0001-8026-4759","observed_orcids":["https://orcid.org/0000-0001-8026-4759"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcus Seldin","raw_affiliation_strings":["Department of Biological Chemistry and Center for Epigenetics and Metabolism, University of California, Irvine, Irvine, CA, USA","Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA","Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA","Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Center for Epigenetics and Metabolism, University of California, Irvine, Irvine, CA, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088751229","display_name":"Xia Yang","orcid":"https://orcid.org/0000-0002-3971-038X","observed_orcids":["https://orcid.org/0000-0002-3971-038X"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xia Yang","raw_affiliation_strings":["Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-3971-038X","affiliations":[{"raw_affiliation_string":"Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024741961","display_name":"Aldons Jake Lusis","orcid":"https://orcid.org/0000-0001-9013-0228","observed_orcids":["https://orcid.org/0000-0001-9013-0228"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aldons J. Lusis","raw_affiliation_strings":["Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA"],"raw_orcid":"https://orcid.org/0000-0001-9013-0228","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA. jlusis@mednet.ucla.edu","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024741961"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":0.4696,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.44537662,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"1","issue":"11","first_page":"1038","last_page":"1050"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9047999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9047999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.06859999895095825,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systems-genetics","display_name":"systems genetics","score":1.0},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.9629999995231628},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.953000009059906},{"id":"https://openalex.org/keywords/multi-omics-integration","display_name":"multi-omics integration","score":0.7379999756813049},{"id":"https://openalex.org/keywords/gene-networks","display_name":"gene networks","score":0.5049999952316284},{"id":"https://openalex.org/keywords/complex-diseases","display_name":"complex diseases","score":0.7200000286102295},{"id":"https://openalex.org/keywords/genetic-databases","display_name":"genetic databases","score":0.42100000381469727},{"id":"https://openalex.org/keywords/reductionist-approach","display_name":"reductionist approach","score":0.5509999990463257},{"id":"https://openalex.org/keywords/nutritional-strategies","display_name":"nutritional strategies","score":0.5080000162124634},{"id":"https://openalex.org/keywords/pharmacological-strategies","display_name":"pharmacological strategies","score":0.8809999823570251},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.6190000176429749},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C173366509","wikidata":"https://www.wikidata.org/wiki/Q206829","display_name":"Reductionism","level":2,"score":0.7039903998374939},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5559833645820618},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5524387955665588},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5474085211753845},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5218614339828491},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5176897048950195},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5145056247711182},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.45798933506011963},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.45530977845191956},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.41676604747772217},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40355467796325684},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.341496080160141},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32520592212677},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.31306445598602295},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.260961651802063},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.21776136755943298},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18421080708503723},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000074705","descriptor_name":"Human Genetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008660","descriptor_name":"Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D049490","descriptor_name":"Systems Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055432","descriptor_name":"Metabolomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059647","descriptor_name":"Gene-Environment Interaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s42255-019-0132-x","doi":"https://doi.org/10.1038/s42255-019-0132-x","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s42255-019-0132-x","pdf_url":null,"source":{"id":"https://openalex.org/S4210232714","display_name":"Nature Metabolism","issn_l":"2522-5812","issn":["2522-5812"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Metabolism","raw_type":"journal-article"},{"id":"pmid:32259026","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32259026","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature metabolism","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:6069349","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7111511","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:7111511","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7111511","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Metab","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt5gg6p5s7","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/5gg6p5s7","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Metabolism, vol 1, iss 11","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:6069349","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7111511","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1322898251","display_name":"Systems genetics approach to inflammatory mechanisms in atherosclerosis","funder_award_id":"R01HL147883","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1393384433","display_name":null,"funder_award_id":"HL147883","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G2022497657","display_name":null,"funder_award_id":"HL138193","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2283908738","display_name":null,"funder_award_id":"HL144651","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G2853954127","display_name":null,"funder_award_id":"104363","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G3407260063","display_name":"Development of a strategy for endocrine axis discovery","funder_award_id":"K99HL138193","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4252304447","display_name":"Pharmacogenomics of Statin Therapy","funder_award_id":"P50GM115318","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5190863296","display_name":"Gut microbiota and metabolite interactions in atherosclerosis","funder_award_id":"R01HL144651","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6916468930","display_name":"DHA Reverses Gene Network Signatures of Fructose-induced Metabolic Syndrome","funder_award_id":"R01DK104363","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7597757235","display_name":null,"funder_award_id":"104363","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7944992577","display_name":null,"funder_award_id":"HL138193","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G8409837061","display_name":null,"funder_award_id":"HL147883","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8629754998","display_name":"A strategy for discovery of endocrine interactions","funder_award_id":"R00HL138193","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8729059623","display_name":null,"funder_award_id":"HL144651","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G891428347","display_name":"Molecular Genetic Approaches in Atherosclerosis Research","funder_award_id":"P01HL028481","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000861505","display_name":"Systems Genetics Dissection of Non-alcoholic Steatohepatitis","funder_award_id":"R01DK117850","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":112,"referenced_works":["https://openalex.org/W1107917109","https://openalex.org/W1240353884","https://openalex.org/W1509405108","https://openalex.org/W1775279835","https://openalex.org/W1839260472","https://openalex.org/W1856941844","https://openalex.org/W1875965364","https://openalex.org/W1966327575","https://openalex.org/W1968358424","https://openalex.org/W1969839871","https://openalex.org/W1982857307","https://openalex.org/W1991336522","https://openalex.org/W1993616000","https://openalex.org/W1999307837","https://openalex.org/W2000653200","https://openalex.org/W2006810478","https://openalex.org/W2007056893","https://openalex.org/W2012224745","https://openalex.org/W2032022203","https://openalex.org/W2035637607","https://openalex.org/W2042863127","https://openalex.org/W2073445330","https://openalex.org/W2073640336","https://openalex.org/W2083380010","https://openalex.org/W2090808827","https://openalex.org/W2091901410","https://openalex.org/W2092072293","https://openalex.org/W2104438296","https://openalex.org/W2106357843","https://openalex.org/W2115944543","https://openalex.org/W2117007075","https://openalex.org/W2120244696","https://openalex.org/W2121604817","https://openalex.org/W2134469465","https://openalex.org/W2139400673","https://openalex.org/W2141618557","https://openalex.org/W2145813488","https://openalex.org/W2152325859","https://openalex.org/W2158534900","https://openalex.org/W2161377204","https://openalex.org/W2165700891","https://openalex.org/W2175465469","https://openalex.org/W2200388872","https://openalex.org/W2264585211","https://openalex.org/W2276765849","https://openalex.org/W2295388714","https://openalex.org/W2326403029","https://openalex.org/W2328393125","https://openalex.org/W2340761255","https://openalex.org/W2342116893","https://openalex.org/W2415103133","https://openalex.org/W2434017435","https://openalex.org/W2437351093","https://openalex.org/W2462242997","https://openalex.org/W2470881009","https://openalex.org/W2473320909","https://openalex.org/W2497350880","https://openalex.org/W2515459743","https://openalex.org/W2518689855","https://openalex.org/W2548971621","https://openalex.org/W2550093768","https://openalex.org/W2558177706","https://openalex.org/W2572375651","https://openalex.org/W2573445961","https://openalex.org/W2581490583","https://openalex.org/W2585175142","https://openalex.org/W2587858407","https://openalex.org/W2588757737","https://openalex.org/W2611138580","https://openalex.org/W2612305061","https://openalex.org/W2612467560","https://openalex.org/W2626606138","https://openalex.org/W2671308999","https://openalex.org/W2725988230","https://openalex.org/W2737849140","https://openalex.org/W2739492614","https://openalex.org/W2742614542","https://openalex.org/W2750397561","https://openalex.org/W2753908609","https://openalex.org/W2759319697","https://openalex.org/W2761275051","https://openalex.org/W2766355510","https://openalex.org/W2767423581","https://openalex.org/W2773307810","https://openalex.org/W2775174939","https://openalex.org/W2784764983","https://openalex.org/W2791536572","https://openalex.org/W2792874817","https://openalex.org/W2794458614","https://openalex.org/W2794479004","https://openalex.org/W2800013084","https://openalex.org/W2800349415","https://openalex.org/W2807098985","https://openalex.org/W2808070351","https://openalex.org/W2808430950","https://openalex.org/W2808845633","https://openalex.org/W2809368942","https://openalex.org/W2886460044","https://openalex.org/W2889722506","https://openalex.org/W2889951764","https://openalex.org/W2894662039","https://openalex.org/W2898905022","https://openalex.org/W2898915993","https://openalex.org/W2910861117","https://openalex.org/W2911274412","https://openalex.org/W2917430324","https://openalex.org/W2924485771","https://openalex.org/W2941892501","https://openalex.org/W2952520709","https://openalex.org/W2952644935","https://openalex.org/W4323874344","https://openalex.org/W7097027624"],"related_works":["https://openalex.org/W2062860983","https://openalex.org/W2078982275","https://openalex.org/W7062468867","https://openalex.org/W214765324","https://openalex.org/W1575277508","https://openalex.org/W2975724441","https://openalex.org/W2342590206","https://openalex.org/W2116054884","https://openalex.org/W81094373","https://openalex.org/W2161927231"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2019-10-25T00:00:00"}