{"id":"https://openalex.org/W2980525909","doi":null,"title":"Combination therapy with extracorporeal shock wave and melatonin markedly attenuated neuropathic pain in rat.","display_name":"Combination therapy with extracorporeal shock wave and melatonin markedly attenuated neuropathic pain in rat.","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2980525909","mag":"2980525909","pmid":"https://pubmed.ncbi.nlm.nih.gov/29118920","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5666067"},"language":"en","primary_location":{"id":"pmid:29118920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29118920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5666067/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112464018","display_name":"Kuan Hung Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Kuan-Hung Chen","raw_affiliation_strings":["Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100852710","display_name":"Chien Hui Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chien-Hui Yang","raw_affiliation_strings":["Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072627858","display_name":"Christopher Glenn Wallace","orcid":"https://orcid.org/0000-0003-1897-9520","observed_orcids":["https://orcid.org/0000-0003-1897-9520"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christopher Glenn Wallace","raw_affiliation_strings":["Department of Plastic Surgery, University Hospital of South ManchesterManchester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plastic Surgery, University Hospital of South ManchesterManchester, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035470831","display_name":"Chung\u2010Ren Lin","orcid":"https://orcid.org/0000-0001-6808-0295","observed_orcids":["https://orcid.org/0000-0001-6808-0295"]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chung-Ren Lin","raw_affiliation_strings":["Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109340043","display_name":"Chia-Kai Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chia-Kai Liu","raw_affiliation_strings":["Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042455926","display_name":"Tsung\u2010Cheng Yin","orcid":"https://orcid.org/0000-0002-2468-6196","observed_orcids":["https://orcid.org/0000-0002-2468-6196"]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tsung-Cheng Yin","raw_affiliation_strings":["Department of Orthopedics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112012205","display_name":"Tien\u2010Hung Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tien-Hung Huang","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100738422","display_name":"Yi\u2010Ling Chen","orcid":"https://orcid.org/0000-0002-9789-2441","observed_orcids":["https://orcid.org/0000-0002-9789-2441"]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yi-Ling Chen","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003281072","display_name":"Cheuk\u2010Kwan Sun","orcid":"https://orcid.org/0000-0002-2524-9684","observed_orcids":["https://orcid.org/0000-0002-2524-9684"]},"institutions":[{"id":"https://openalex.org/I4210091198","display_name":"E-Da Hospital","ror":"https://ror.org/00eh7f421","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210091198"]},{"id":"https://openalex.org/I98298690","display_name":"I-Shou University","ror":"https://ror.org/04d7e4m76","country_code":"TW","type":"education","lineage":["https://openalex.org/I98298690"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Cheuk-Kwan Sun","raw_affiliation_strings":["Department of Emergency Medicine, E-Da Hospital, I-Shou University School of Medicine for International StudentsKaohsiung 82445, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, E-Da Hospital, I-Shou University School of Medicine for International StudentsKaohsiung 82445, Taiwan, R.O.C","institution_ids":["https://openalex.org/I4210091198","https://openalex.org/I98298690"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108117497","display_name":"Hon-Kan Yip","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143578492","display_name":"Asia University","ror":"https://ror.org/038a1tp19","country_code":"TW","type":"education","lineage":["https://openalex.org/I143578492"]},{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I4210093821","display_name":"Kaohsiung Chang Gung Memorial Hospital","ror":"https://ror.org/00k194y12","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210093821"]},{"id":"https://openalex.org/I4210126829","display_name":"China Medical University Hospital","ror":"https://ror.org/0368s4g32","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210126829"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hon-Kan Yip","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","Department of Medical Research, China Medical University Hospital, China Medical UniversityTaichung 40402, Taiwan, R.O.C","Department of Nursing, Asia UniversityTaichung 41354, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]},{"raw_affiliation_string":"Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]},{"raw_affiliation_string":"Center for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung 83301, Taiwan, R.O.C","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I4210093821"]},{"raw_affiliation_string":"Department of Medical Research, China Medical University Hospital, China Medical UniversityTaichung 40402, Taiwan, R.O.C","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I4210126829"]},{"raw_affiliation_string":"Department of Nursing, Asia UniversityTaichung 41354, Taiwan, R.O.C","institution_ids":["https://openalex.org/I143578492"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.166,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.91281154,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"9","issue":"10","first_page":"4593","last_page":"4606"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extracorporeal-shock-wave-therapy","display_name":"extracorporeal shock wave therapy","score":0.925000011920929},{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":1.0},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.9589999914169312},{"id":"https://openalex.org/keywords/chronic-constriction-injury","display_name":"chronic constriction injury","score":0.9629999995231628},{"id":"https://openalex.org/keywords/sciatic-nerve","display_name":"sciatic nerve","score":0.9430000185966492},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.9340000152587891},{"id":"https://openalex.org/keywords/dorsal-root-ganglia","display_name":"dorsal root ganglia","score":0.8730000257492065},{"id":"https://openalex.org/keywords/spinal-cord-dorsal-horn","display_name":"dorsal horn","score":0.906000018119812},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8029999732971191},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8259999752044678},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.4970000088214874},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9100000262260437},{"id":"https://openalex.org/keywords/nav1-3","display_name":"Nav1.3","score":0.7799999713897705},{"id":"https://openalex.org/keywords/nav1-8","display_name":"Nav1.8","score":0.9860000014305115},{"id":"https://openalex.org/keywords/nav1-9","display_name":"Nav1.9","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pain-facilitation","display_name":"pain facilitation","score":0.5730000138282776},{"id":"https://openalex.org/keywords/mitochondrial-damage","display_name":"mitochondrial damage","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.7923393249511719},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6313750147819519},{"id":"https://openalex.org/C2781149210","wikidata":"https://www.wikidata.org/wiki/Q307869","display_name":"Sciatic nerve","level":2,"score":0.6272084712982178},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.5471656322479248},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.531541109085083},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.493203341960907},{"id":"https://openalex.org/C51551487","wikidata":"https://www.wikidata.org/wiki/Q2043632","display_name":"p38 mitogen-activated protein kinases","level":4,"score":0.45449769496917725},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4529600739479065},{"id":"https://openalex.org/C2779245659","wikidata":"https://www.wikidata.org/wiki/Q1633866","display_name":"Hyperalgesia","level":4,"score":0.4287511706352234},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4207732081413269},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3862541913986206},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2903907895088196},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.28758490085601807},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.21121862530708313},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1443251669406891},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.14377403259277344},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09506300091743469}],"mesh":[],"locations_count":3,"locations":[{"id":"pmid:29118920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29118920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of translational research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5666067","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5666067/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},{"id":"mag:2980525909","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29118920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5666067","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5666067/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Transl Res","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W203673464","https://openalex.org/W1841237986","https://openalex.org/W1879507096","https://openalex.org/W1934204403","https://openalex.org/W1942074295","https://openalex.org/W1959152155","https://openalex.org/W1963857381","https://openalex.org/W1967997160","https://openalex.org/W1981435820","https://openalex.org/W1993039838","https://openalex.org/W1993766157","https://openalex.org/W1997515903","https://openalex.org/W2000427819","https://openalex.org/W2000574545","https://openalex.org/W2006161356","https://openalex.org/W2007939267","https://openalex.org/W2036108169","https://openalex.org/W2040698392","https://openalex.org/W2058020736","https://openalex.org/W2059234147","https://openalex.org/W2059646315","https://openalex.org/W2060630008","https://openalex.org/W2065051702","https://openalex.org/W2065588637","https://openalex.org/W2067212451","https://openalex.org/W2069977126","https://openalex.org/W2071488336","https://openalex.org/W2082958467","https://openalex.org/W2092918915","https://openalex.org/W2093967086","https://openalex.org/W2098227317","https://openalex.org/W2099749229","https://openalex.org/W2121270079","https://openalex.org/W2131188261","https://openalex.org/W2133316133","https://openalex.org/W2135247591","https://openalex.org/W2137367741","https://openalex.org/W2144042624","https://openalex.org/W2149599746","https://openalex.org/W2154507501","https://openalex.org/W2159059571","https://openalex.org/W2166939791","https://openalex.org/W2169299798","https://openalex.org/W2278128380","https://openalex.org/W2284966345","https://openalex.org/W2301250741","https://openalex.org/W2311672730","https://openalex.org/W2317729401","https://openalex.org/W2322058666","https://openalex.org/W2406239494","https://openalex.org/W2477369408","https://openalex.org/W2478981212","https://openalex.org/W2534361057","https://openalex.org/W2544746799","https://openalex.org/W2613947589"],"related_works":["https://openalex.org/W2910075829","https://openalex.org/W3029200145","https://openalex.org/W3030298692","https://openalex.org/W1971879533","https://openalex.org/W2596087635","https://openalex.org/W2098203011","https://openalex.org/W25485283","https://openalex.org/W3093741747","https://openalex.org/W1976742435","https://openalex.org/W2170349508"],"abstract_inverted_index":{"This":[0],"study":[1],"tested":[2],"the":[3,33,68,144,178,198],"hypothesis":[4],"that":[5],"combination":[6,206],"therapy":[7,207],"using":[8],"extracorporeal":[9],"shock":[10],"wave":[11],"(ECSW)-melatonin":[12],"(Mel)":[13],"was":[14,25],"superior":[15],"to":[16,32,175,195],"either":[17],"alone":[18],"at":[19],"ameliorating":[20],"neuropathic":[21],"pain":[22],"(NP).":[23],"NP":[24,210],"induced":[26,211],"by":[27,212],"chronic":[28],"constriction":[29],"injury":[30],"(CCI)":[31],"left":[34],"sciatic":[35,169],"nerve":[36,170],"in":[37,80,84,89,93,129,151,155,168],"rats.":[38],"Animals":[39],"were":[40,78],"categorized":[41],"into":[42],"sham":[43],"control":[44],"(group":[45,49,52,55,59],"1),":[46],"CCI":[47],"only":[48],"2),":[50],"CCI-ECSW":[51],"3),":[53],"CCI-Mel":[54],"4)":[56],"and":[57,64,96,100,107,124,133,166],"CCI-ECSW-Mel":[58],"5).":[60],"By":[61],"days":[62],"2":[63],"8":[65],"after":[66],"CCI,":[67],"mechanical":[69],"paw":[70,74],"withdrawal":[71,75],"threshold":[72],"(MPWT)/thermal":[73],"latency":[76],"(TPWL)":[77],"highest":[79],"group":[81,85,90,152,156],"2,":[82],"lowest":[83],"1,":[86],"significantly":[87,102,149],"lower":[88],"5":[91],"than":[92,154],"groups":[94,105,180,200],"3":[95,106,157],"4":[97,153],"(all":[98,158,181,201],"p<0.0001),":[99],"not":[101],"different":[103],"between":[104],"4.":[108],"The":[109,160],"protein":[110,161],"expressions":[111,162,186],"of":[112,141,163],"inflammatory":[113],"(TNF-\u03b1/NF-\u03baB/MMP-9/IL-1\u00df/GFAP/ox42),":[114],"oxidative-stress":[115],"(NOX-1/NOX-2/NOX-4/oxidized":[116],"protein),":[117],"DNA/mitochondrial-damaged":[118],"(\u03b3-H2AX/cytosolic":[119],"mitochondria),":[120],"apoptotic":[121],"(cleaved":[122],"capase-3/PARP),":[123],"MAPK":[125],"family":[126],"biomarkers":[127],"(p-P38/p-JNK/p-ERK1/2)":[128],"dorsal":[130,135],"root":[131],"ganglia":[132],"spinal":[134],"horn":[136],"expressed":[137],"a":[138],"similar":[139],"pattern":[140,174,194],"MPWT/TPWL":[142],"among":[143,177,197],"five":[145,179,199],"groups,":[146],"except":[147],"for":[148],"higher":[150],"p<0.0001).":[159,202],"Nav.1.3,":[164],"Nav.1.8":[165],"Nav.1.9":[167],"displayed":[171,191],"an":[172,192],"identical":[173,193],"inflammation":[176,196],"p<0.001).":[182],"Pain":[183],"facilitated":[184],"cellular":[185],"(p-P38+/peripherin+":[187],"cells,":[188],"P38+/NF200+":[189],"cells)":[190],"In":[203],"conclusion,":[204],"ECSW-Mel":[205],"markedly":[208],"ameliorated":[209],"CCI.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-10-25T00:00:00"}