{"id":"https://openalex.org/W2980219860","doi":"https://doi.org/10.1371/journal.pone.0223238","title":"Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson\u2019s disease","display_name":"Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson\u2019s disease","publication_year":2019,"publication_date":"2019-10-10","ids":{"openalex":"https://openalex.org/W2980219860","doi":"https://doi.org/10.1371/journal.pone.0223238","mag":"2980219860","pmid":"https://pubmed.ncbi.nlm.nih.gov/31600256","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6786615"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0223238","doi":"https://doi.org/10.1371/journal.pone.0223238","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0223238","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0223238&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0223238&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029147695","display_name":"Laura Bordoni","orcid":"https://orcid.org/0000-0001-6968-1164","observed_orcids":["https://orcid.org/0000-0001-6968-1164"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Bordoni","raw_affiliation_strings":["School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071965992","display_name":"Rosita Gabbianelli","orcid":"https://orcid.org/0000-0003-0037-7740","observed_orcids":["https://orcid.org/0000-0003-0037-7740"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosita Gabbianelli","raw_affiliation_strings":["School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038105619","display_name":"Donatella Fedeli","orcid":"https://orcid.org/0000-0002-3260-5288","observed_orcids":["https://orcid.org/0000-0002-3260-5288"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Donatella Fedeli","raw_affiliation_strings":["School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Molecular Biology Unit, University of Camerino, Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086294220","display_name":"Dennis Fiorini","orcid":"https://orcid.org/0000-0001-5055-6099","observed_orcids":["https://orcid.org/0000-0001-5055-6099"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Dennis Fiorini","raw_affiliation_strings":["School of Science and Technology, Chemistry Unit, University of Camerino, Camerino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Science and Technology, Chemistry Unit, University of Camerino, Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046717517","display_name":"Ina Bergheim","orcid":"https://orcid.org/0000-0002-3356-4115","observed_orcids":["https://orcid.org/0000-0002-3356-4115"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ina Bergheim","raw_affiliation_strings":["Department of Nutritional Sciences, RF Molecular Nutritional Science, University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences, RF Molecular Nutritional Science, University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I129774422"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101674969","display_name":"Cheng Jun Jin","orcid":"https://orcid.org/0000-0001-7235-0382","observed_orcids":["https://orcid.org/0000-0001-7235-0382"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Cheng Jun Jin","raw_affiliation_strings":["Institute of Nutritional Sciences, SD Model Systems of Molecular Nutrition, Friedrich-Schiller-University, Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Nutritional Sciences, SD Model Systems of Molecular Nutrition, Friedrich-Schiller-University, Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042618739","display_name":"Lisa Marinelli","orcid":"https://orcid.org/0000-0001-8611-6538","observed_orcids":["https://orcid.org/0000-0001-8611-6538"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lisa Marinelli","raw_affiliation_strings":["Department of Pharmacy, University of \"G. D'Annunzio\", Chieti, Italy","Department of Pharmacy, University of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, University of \"G. D'Annunzio\", Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]},{"raw_affiliation_string":"Department of Pharmacy, University of","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019767774","display_name":"Antonio Di Stefano","orcid":"https://orcid.org/0000-0002-3042-2234","observed_orcids":["https://orcid.org/0000-0002-3042-2234"]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonio Di Stefano","raw_affiliation_strings":["Department of Pharmacy, University of \"G. D'Annunzio\", Chieti, Italy","Department of Pharmacy, University of"],"raw_orcid":"https://orcid.org/0000-0002-3042-2234","affiliations":[{"raw_affiliation_string":"Department of Pharmacy, University of \"G. D'Annunzio\", Chieti, Italy","institution_ids":["https://openalex.org/I39387349"]},{"raw_affiliation_string":"Department of Pharmacy, University of","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062044858","display_name":"Cinzia Nasuti","orcid":"https://orcid.org/0000-0002-4470-7345","observed_orcids":["https://orcid.org/0000-0002-4470-7345"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Cinzia Nasuti","raw_affiliation_strings":["School of Pharmacy, Pharmacology Unit, University of Camerino, Camerino, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4470-7345","affiliations":[{"raw_affiliation_string":"School of Pharmacy, Pharmacology Unit, University of Camerino, Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5062044858"],"corresponding_institution_ids":["https://openalex.org/I112859197"],"apc_list":{"value":1595,"currency":"USD","value_usd":1595},"apc_paid":{"value":1595,"currency":"USD","value_usd":1595},"fwci":3.0362,"has_fulltext":true,"cited_by_count":50,"citation_normalized_percentile":{"value":0.91425493,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"14","issue":"10","first_page":"e0223238","last_page":"e0223238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.8568999767303467,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.8568999767303467,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":0.045099999755620956,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.019099999219179153,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9559999704360962},{"id":"https://openalex.org/keywords/electrolyzed-reduced-water","display_name":"electrolyzed reduced water","score":0.9909999966621399},{"id":"https://openalex.org/keywords/permethrin","display_name":"permethrin","score":0.8450000286102295},{"id":"https://openalex.org/keywords/pesticide-neurotoxicity","display_name":"pesticide neurotoxicity","score":0.7789999842643738},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.8600000143051147},{"id":"https://openalex.org/keywords/intestinal-barrier","display_name":"intestinal barrier","score":0.7250000238418579},{"id":"https://openalex.org/keywords/fecal-microbiota","display_name":"fecal microbiota","score":0.871999979019165},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.8960000276565552},{"id":"https://openalex.org/keywords/occludin","display_name":"occludin","score":0.7049999833106995},{"id":"https://openalex.org/keywords/zo-1","display_name":"ZO-1","score":0.8809999823570251},{"id":"https://openalex.org/keywords/butyrate-producing-bacteria","display_name":"butyrate-producing bacteria","score":0.8640000224113464},{"id":"https://openalex.org/keywords/butyrate","display_name":"butyrate","score":0.8579999804496765},{"id":"https://openalex.org/keywords/lachnospira","display_name":"Lachnospira","score":0.8949999809265137},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.6978311538696289},{"id":"https://openalex.org/C2777226302","wikidata":"https://www.wikidata.org/wiki/Q233345","display_name":"Ileum","level":2,"score":0.6612975001335144},{"id":"https://openalex.org/C2779704485","wikidata":"https://www.wikidata.org/wiki/Q3825240","display_name":"Lachnospiraceae","level":5,"score":0.6526970267295837},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.627178430557251},{"id":"https://openalex.org/C2781071285","wikidata":"https://www.wikidata.org/wiki/Q17141320","display_name":"Intestinal permeability","level":2,"score":0.5845952033996582},{"id":"https://openalex.org/C2776809568","wikidata":"https://www.wikidata.org/wiki/Q134955","display_name":"Duodenum","level":2,"score":0.5666394233703613},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4807719588279724},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.42413339018821716},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3689413368701935},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.36530524492263794},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.35020697116851807},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31545624136924744},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2267356514930725},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2203945815563202},{"id":"https://openalex.org/C2777695942","wikidata":"https://www.wikidata.org/wiki/Q149075","display_name":"Firmicutes","level":4,"score":0.17715445160865784},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16562116146087646},{"id":"https://openalex.org/C42062724","wikidata":"https://www.wikidata.org/wiki/Q1209205","display_name":"16S ribosomal RNA","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004572","descriptor_name":"Electrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010302","descriptor_name":"Parkinson Disease, Secondary","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D010302","descriptor_name":"Parkinson Disease, Secondary","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010302","descriptor_name":"Parkinson Disease, Secondary","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010302","descriptor_name":"Parkinson Disease, Secondary","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D026023","descriptor_name":"Permethrin","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1371/journal.pone.0223238","doi":"https://doi.org/10.1371/journal.pone.0223238","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0223238","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0223238&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6786615","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6786615","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:31600256","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31600256","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubblicazioni.unicam.it:11581/433862","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11581/433862","pdf_url":"http://hdl.handle.net/11581/433862","source":{"id":"https://openalex.org/S4306400819","display_name":"Unicam Scientific Publications (University of Camerino)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I112859197","host_organization_name":"Universit\u00e0 di Camerino","host_organization_lineage":["https://openalex.org/I112859197"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:bc156ff07c014921926ed98fccfbef0d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bc156ff07c014921926ed98fccfbef0d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 14, Iss 10, p e0223238 (2019)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/9966680","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Positive_effect_of_an_electrolyzed_reduced_water_on_gut_permeability_fecal_microbiota_and_liver_in_an_animal_model_of_Parkinson_s_disease/9966680","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0223238","doi":"https://doi.org/10.1371/journal.pone.0223238","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0223238","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0223238&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2980219860.pdf","grobid_xml":"https://content.openalex.org/works/W2980219860.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1903888485","https://openalex.org/W2002703043","https://openalex.org/W2017410917","https://openalex.org/W2034285706","https://openalex.org/W2036600184","https://openalex.org/W2039843492","https://openalex.org/W2053744831","https://openalex.org/W2059198752","https://openalex.org/W2067740038","https://openalex.org/W2072970694","https://openalex.org/W2074752351","https://openalex.org/W2079183971","https://openalex.org/W2084307273","https://openalex.org/W2086810938","https://openalex.org/W2090760015","https://openalex.org/W2097335121","https://openalex.org/W2113569012","https://openalex.org/W2124351063","https://openalex.org/W2132916165","https://openalex.org/W2163878401","https://openalex.org/W2169657429","https://openalex.org/W2170024099","https://openalex.org/W2280200013","https://openalex.org/W2470512478","https://openalex.org/W2517359801","https://openalex.org/W2536578467","https://openalex.org/W2548754181","https://openalex.org/W2551584212","https://openalex.org/W2570860549","https://openalex.org/W2586251226","https://openalex.org/W2588841770","https://openalex.org/W2756212061","https://openalex.org/W2797668595","https://openalex.org/W2800111908","https://openalex.org/W2807153072","https://openalex.org/W2886724356","https://openalex.org/W2905177566","https://openalex.org/W2908414305","https://openalex.org/W2916481157","https://openalex.org/W2948300621"],"related_works":["https://openalex.org/W2954857386","https://openalex.org/W7066557272","https://openalex.org/W7049365742","https://openalex.org/W2895750492","https://openalex.org/W2908414305","https://openalex.org/W4388518496","https://openalex.org/W4396691206","https://openalex.org/W4400960527","https://openalex.org/W2322057494","https://openalex.org/W2789728109"],"abstract_inverted_index":{"There":[0],"is":[1],"growing":[2],"awareness":[3],"within":[4],"the":[5,9,13,16,19,66,201,205,215,226,263,268],"scientific":[6],"community":[7],"of":[8,21,130,161,176,182,231,239,243,288,297],"strong":[10],"connection":[11],"between":[12],"inflammation":[14,279],"in":[15,47,54,104,116,134,140,145,150,155,174,180,200,217,225,258,292],"intestine":[17],"and":[18,59,97,100,122,127,157,164,184,196,219,295],"pathogenesis":[20],"Parkinson's":[22],"disease":[23],"(PD).":[24],"In":[25,125,266],"previous":[26],"studies":[27],"we":[28,42,63],"developed":[29],"a":[30],"PD":[31,269],"animal":[32,49,270],"model":[33,50,271],"exposing":[34],"pup":[35],"rats":[36,178,298],"to":[37,44,75,87,120,223,262,301],"permethrin":[38],"(PERM)":[39],"pesticide.":[40],"Here,":[41],"intended":[43],"explore":[45],"whether":[46],"our":[48],"there":[51],"were":[52,89,102,172,221,256,299],"changes":[53,302],"gut":[55,108,283,304],"permeability,":[56,109],"fecal":[57],"microbiota":[58,188],"hepatic":[60,278],"injury.":[61],"Moreover,":[62],"tested":[64],"if":[65],"co-treatment":[67,206,290],"with":[68,92,207,251,277,281],"an":[69],"electrolyzed":[70],"reduced":[71],"(ERW)":[72],"was":[73,114,132,148,193,209],"effective":[74],"protect":[76],"against":[77,211],"alterations":[78],"induced":[79],"by":[80,111],"PERM.":[81],"Rats":[82],"(from":[83],"postnatal":[84],"day":[85],"6":[86],"21)":[88],"gavaged":[90],"daily":[91],"PERM,":[93],"PERM+ERW":[94,123,158,183,259],"or":[95],"vehicle":[96],"gut,":[98,293],"liver":[99,294],"feces":[101],"analyzed":[103],"2-months-old":[105],"rats.":[106,186],"Increased":[107],"measured":[110,139,154],"FITC-dextran":[112],"assay,":[113],"detected":[115,257],"PERM":[117,141,156,202,212],"group":[118,136,260],"compared":[119,261],"control":[121,135,151,185,227],"groups.":[124,159,265],"duodenum":[126,146],"ileum,":[128],"concentration":[129],"occludin":[131],"higher":[133,149,173,252],"than":[137,152,179],"those":[138,153,181,224],"group,":[142,203],"whereas":[143,204],"only":[144],"ZO-1":[147],"Number":[160],"inflammatory":[162],"focis":[163],"neutrophils":[165],"as":[166,168,236],"well":[167],"iNOS":[169],"protein":[170],"levels":[171,255],"livers":[175],"PERM-treated":[177],"Fecal":[187],"analysis":[189],"revealed":[190],"that":[191],"Lachnospira":[192,218],"less":[194],"abundant":[195,199],"Defluviitaleaceae":[197,220],"more":[198],"ERW":[208,289],"protective":[210],"treatment":[213],"since":[214],"abundances":[216,230],"similar":[222],"group.":[228],"Higher":[229],"butyrate-":[232],"producing":[233],"bacteria":[234],"such":[235],"Blautia,":[237],"U.m.":[238,242],"Lachnospiraceae":[240],"family,":[241,245],"Ruminococcaceae":[244],"Papillibacter,":[246],"Roseburia,":[247],"Intestinimonas,":[248],"Shuttleworthia":[249],"together":[250,276],"butyric":[253],"acid":[254],"other":[264],"conclusion,":[267],"showed":[272],"increased":[273],"intestinal":[274],"permeability":[275],"correlated":[280],"altered":[282],"microbiota.":[284,305],"The":[285],"positive":[286],"effects":[287],"observed":[291],"brain":[296],"linked":[300],"on":[303]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-10-18T00:00:00"}