{"id":"https://openalex.org/W2979819052","doi":null,"title":"Why Doesn\u2019t a Mother Reject a Genetically Different Fetus?","display_name":"Why Doesn\u2019t a Mother Reject a Genetically Different Fetus?","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2979819052","mag":"2979819052"},"language":"en","primary_location":{"id":"pmh:oai:touroscholar.touro.edu:sjlcas-1192","doi":null,"is_oa":true,"landing_page_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","pdf_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","source":{"id":"https://openalex.org/S4377196437","display_name":"Touro Scholar (Touro College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200437953","host_organization_name":"Touro College","host_organization_lineage":["https://openalex.org/I200437953"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Science Journal of the Lander College of Arts and Sciences","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050698119","display_name":"Devora Krumholtz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Devora Krumholtz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050698119"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1037,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.37788669,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"11","issue":"2","first_page":"3","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12715","display_name":"Pregnancy-related medical research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-fetal-immune-tolerance","display_name":"maternal-fetal immune tolerance","score":0.7089999914169312},{"id":"https://openalex.org/keywords/fetal-rejection","display_name":"fetal rejection","score":0.8330000042915344},{"id":"https://openalex.org/keywords/maternal-immune-system","display_name":"maternal immune system","score":0.7889999747276306},{"id":"https://openalex.org/keywords/pregnancy-immunology","display_name":"pregnancy immunology","score":0.7260000109672546},{"id":"https://openalex.org/keywords/immunosuppression-in-pregnancy","display_name":"immunosuppression in pregnancy","score":0.6100000143051147},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.5680000185966492},{"id":"https://openalex.org/keywords/mechanical-barriers","display_name":"mechanical barriers","score":0.5440000295639038},{"id":"https://openalex.org/keywords/organ-transplantation","display_name":"organ transplantation","score":0.5799999833106995},{"id":"https://openalex.org/keywords/reproductive-immunology","display_name":"reproductive immunology","score":0.5109999775886536}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37379634380340576}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:touroscholar.touro.edu:sjlcas-1192","doi":null,"is_oa":true,"landing_page_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","pdf_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","source":{"id":"https://openalex.org/S4377196437","display_name":"Touro Scholar (Touro College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200437953","host_organization_name":"Touro College","host_organization_lineage":["https://openalex.org/I200437953"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Science Journal of the Lander College of Arts and Sciences","raw_type":"article"},{"id":"mag:2979819052","doi":null,"is_oa":false,"landing_page_url":"https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1192&context=sjlcas","pdf_url":null,"source":{"id":"https://openalex.org/S4306532697","display_name":"The Science Journal of the Lander College of Arts and Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"The Science Journal of the Lander College of Arts and Sciences","raw_type":null}],"best_oa_location":{"id":"pmh:oai:touroscholar.touro.edu:sjlcas-1192","doi":null,"is_oa":true,"landing_page_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","pdf_url":"https://touroscholar.touro.edu/sjlcas/vol11/iss2/3","source":{"id":"https://openalex.org/S4377196437","display_name":"Touro Scholar (Touro College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200437953","host_organization_name":"Touro College","host_organization_lineage":["https://openalex.org/I200437953"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Science Journal of the Lander College of Arts and Sciences","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2979819052.pdf","grobid_xml":"https://content.openalex.org/works/W2979819052.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W585194358","https://openalex.org/W1627464957","https://openalex.org/W1983910492","https://openalex.org/W2001542236","https://openalex.org/W2082525904","https://openalex.org/W2150763544","https://openalex.org/W2252420057","https://openalex.org/W2785412519"],"related_works":["https://openalex.org/W2252420057","https://openalex.org/W2031058274","https://openalex.org/W2130919690","https://openalex.org/W2907855271","https://openalex.org/W2082525904","https://openalex.org/W4253824607","https://openalex.org/W7127408","https://openalex.org/W2129137454","https://openalex.org/W4255381285","https://openalex.org/W4282047155"],"abstract_inverted_index":{"Many":[0],"basic":[1],"multicellular":[2],"organisms":[3],"possess":[4],"some":[5],"form":[6],"of":[7,16,82,90,113,120,148,167],"immune":[8,54,75,93,121,133],"response":[9],"to":[10,70,127,162],"protect":[11],"themselves":[12],"against":[13],"the":[14,33,37,52,73,91,111,132,139,146,165],"invasion":[15],"foreign":[17],"objects.":[18],"It":[19],"was":[20],"not":[21],"until":[22],"British":[23],"scientist,":[24],"Peter":[25],"Medawar":[26],"proposed":[27,140],"a":[28,83,96],"fundamental":[29],"question":[30],"that":[31,68,157],"changed":[32],"way":[34],"researchers":[35],"studied":[36],"maternofetal":[38],"relationship.":[39],"A":[40],"fetus,":[41],"being":[42],"genetically":[43],"different":[44],"from":[45],"its":[46],"mother":[47],"should":[48],"be":[49],"rejected":[50],"by":[51],"maternal":[53,74,92],"system,":[55,94],"however,":[56],"it":[57],"is":[58,152,160],"not.":[59],"Researchers":[60],"have":[61,103],"since":[62],"discovered":[63],"and":[64,87,95],"developed":[65],"several":[66],"mechanisms":[67,141],"aim":[69],"explain":[71,164],"how":[72,149],"system":[76],"prevents":[77],"fetal":[78,150,168],"rejection.":[79,169],"The":[80],"formation":[81],"mechanical":[84],"barrier,":[85],"general":[86],"local":[88],"suppression":[89],"shift":[97],"in":[98,110,125],"cytokine":[99],"concentration":[100],"during":[101,123],"pregnancy":[102],"been":[104],"suggested":[105],"as":[106],"reasons.":[107],"Forthcoming":[108],"discoveries":[109],"field":[112],"reproductive":[114],"immunology":[115],"may":[116],"further":[117],"one\u2019s":[118],"understanding":[119,147],"regulation":[122],"pregnancy,":[124],"addition":[126],"other":[128],"applications,":[129],"such":[130],"as,":[131],"responses":[134],"regarding":[135],"organ":[136],"transplants.":[137],"Although":[138],"mentioned":[142],"above":[143],"helped":[144],"improve":[145],"rejection":[151],"avoided,":[153],"many":[154],"scientists":[155],"concur":[156],"additional":[158],"research":[159],"required":[161],"adequately":[163],"prevention":[166]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-10-18T00:00:00"}
