{"id":"https://openalex.org/W2979408352","doi":"https://doi.org/10.1111/imj.14649","title":"Short\u2010term colectomy is avoided in over half of regional patients failing medical therapy for acute severe ulcerative colitis with co\u2010ordinated transfer and tertiary care","display_name":"Short\u2010term colectomy is avoided in over half of regional patients failing medical therapy for acute severe ulcerative colitis with co\u2010ordinated transfer and tertiary care","publication_year":2019,"publication_date":"2019-10-07","ids":{"openalex":"https://openalex.org/W2979408352","doi":"https://doi.org/10.1111/imj.14649","mag":"2979408352","pmid":"https://pubmed.ncbi.nlm.nih.gov/31589361"},"language":"en","primary_location":{"id":"doi:10.1111/imj.14649","doi":"https://doi.org/10.1111/imj.14649","is_oa":false,"landing_page_url":"https://doi.org/10.1111/imj.14649","pdf_url":null,"source":{"id":"https://openalex.org/S60716783","display_name":"Internal Medicine Journal","issn_l":"1444-0903","issn":["1444-0903","1445-5994"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075128677","display_name":"Desmond Patrick","orcid":"https://orcid.org/0000-0002-1367-6945","observed_orcids":["https://orcid.org/0000-0002-1367-6945"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]},{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Desmond Patrick","raw_affiliation_strings":["Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia","Faculty of Medicine University of Queensland Brisbane Queensland Australia","Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0002-1367-6945","affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia","institution_ids":["https://openalex.org/I2799393793"]},{"raw_affiliation_string":"Faculty of Medicine University of Queensland Brisbane Queensland Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017855145","display_name":"James D. Doecke","orcid":"https://orcid.org/0000-0003-2863-0293","observed_orcids":["https://orcid.org/0000-0003-2863-0293"]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]},{"id":"https://openalex.org/I4210141844","display_name":"Australian e-Health Research Centre","ror":"https://ror.org/04ywhbc61","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801244131","https://openalex.org/I2801453606","https://openalex.org/I4210141844","https://openalex.org/I4387156119"]},{"id":"https://openalex.org/I4210142128","display_name":"CSIRO Health and Biosecurity","ror":"https://ror.org/03jh4jw93","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210142128","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"James D. Doecke","raw_affiliation_strings":["CSIRO Health and Biosecurity/Australian E-Health Research Centre Royal Brisbane and Women's Hospital Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Health and Biosecurity/Australian E-Health Research Centre Royal Brisbane and Women's Hospital Brisbane Queensland Australia","institution_ids":["https://openalex.org/I1292875679","https://openalex.org/I2799393793","https://openalex.org/I4210141844","https://openalex.org/I4210142128"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002717993","display_name":"James R. Irwin","orcid":"https://orcid.org/0000-0002-6804-1752","observed_orcids":["https://orcid.org/0000-0002-6804-1752"]},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"James Irwin","raw_affiliation_strings":["Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087839578","display_name":"Katherine Hanigan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Katherine Hanigan","raw_affiliation_strings":["Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006070385","display_name":"Lisa A. Simms","orcid":"https://orcid.org/0000-0002-5387-7397","observed_orcids":["https://orcid.org/0000-0002-5387-7397"]},"institutions":[{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Lisa A. Simms","raw_affiliation_strings":["Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia","institution_ids":["https://openalex.org/I217937681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056604982","display_name":"Mariko Howlett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Mariko Howlett","raw_affiliation_strings":["Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia","institution_ids":["https://openalex.org/I2799393793"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018605111","display_name":"Graham L Radford\u2010Smith","orcid":"https://orcid.org/0000-0002-2047-6239","observed_orcids":["https://orcid.org/0000-0002-2047-6239"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]},{"id":"https://openalex.org/I217937681","display_name":"QIMR Berghofer Medical Research Institute","ror":"https://ror.org/004y8wk30","country_code":"AU","type":"facility","lineage":["https://openalex.org/I217937681"]},{"id":"https://openalex.org/I2799393793","display_name":"Royal Brisbane and Women's Hospital","ror":"https://ror.org/05p52kj31","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2799393793","https://openalex.org/I2801244131"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Graham L. Radford\u2010Smith","raw_affiliation_strings":["Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia","Faculty of Medicine University of Queensland Brisbane Queensland Australia","Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology Royal Brisbane and Women's Hospital Brisbane Queensland Australia","institution_ids":["https://openalex.org/I2799393793"]},{"raw_affiliation_string":"Faculty of Medicine University of Queensland Brisbane Queensland Australia","institution_ids":["https://openalex.org/I165143802"]},{"raw_affiliation_string":"Gut Health Research Group QIMR Berghofer Medical Research Institute Brisbane Queensland Australia","institution_ids":["https://openalex.org/I217937681"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5075128677"],"corresponding_institution_ids":["https://openalex.org/I165143802","https://openalex.org/I217937681","https://openalex.org/I2799393793"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":null,"fwci":0.1823,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.52171347,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"50","issue":"7","first_page":"823","last_page":"829"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12518","display_name":"Diverticular Disease and Complications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-severe-ulcerative-colitis","display_name":"acute severe ulcerative colitis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/colectomy-avoidance","display_name":"colectomy avoidance","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hospital-transfer","display_name":"hospital transfer","score":0.5929999947547913},{"id":"https://openalex.org/keywords/regional-hospital","display_name":"regional hospital","score":0.5070000290870667},{"id":"https://openalex.org/keywords/tertiary-care-referral","display_name":"tertiary care referral","score":0.8130000233650208},{"id":"https://openalex.org/keywords/salvage-therapy","display_name":"salvage therapy","score":0.9670000076293945},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9589673280715942},{"id":"https://openalex.org/C2776667177","wikidata":"https://www.wikidata.org/wiki/Q1779148","display_name":"Colectomy","level":4,"score":0.8405157327651978},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.8361791372299194},{"id":"https://openalex.org/C2776135927","wikidata":"https://www.wikidata.org/wiki/Q5242559","display_name":"Referral","level":2,"score":0.4935058355331421},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4773021936416626},{"id":"https://openalex.org/C158739034","wikidata":"https://www.wikidata.org/wiki/Q1907114","display_name":"Metropolitan area","level":2,"score":0.4727906882762909},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.42499661445617676},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3733143210411072},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.34651368856430054},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3106551766395569},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.23405444622039795},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.05992808938026428},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003082","descriptor_name":"Colectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063128","descriptor_name":"Tertiary Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/imj.14649","doi":"https://doi.org/10.1111/imj.14649","is_oa":false,"landing_page_url":"https://doi.org/10.1111/imj.14649","pdf_url":null,"source":{"id":"https://openalex.org/S60716783","display_name":"Internal Medicine Journal","issn_l":"1444-0903","issn":["1444-0903","1445-5994"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal Medicine Journal","raw_type":"journal-article"},{"id":"pmid:31589361","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31589361","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Internal medicine journal","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1182597593","https://openalex.org/W1479962979","https://openalex.org/W1986066100","https://openalex.org/W2025341072","https://openalex.org/W2065637841","https://openalex.org/W2085161424","https://openalex.org/W2089991488","https://openalex.org/W2095805757","https://openalex.org/W2106136830","https://openalex.org/W2171789845","https://openalex.org/W2800093627","https://openalex.org/W6676308783"],"related_works":["https://openalex.org/W2761990651","https://openalex.org/W2604531487","https://openalex.org/W3032593706","https://openalex.org/W2914006668","https://openalex.org/W2755424312","https://openalex.org/W7125166395","https://openalex.org/W3132645891","https://openalex.org/W3110117649","https://openalex.org/W2140612434","https://openalex.org/W1976891063"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"AIMS:":[2],"Many":[3],"patients":[4,111,125,154,183],"presenting":[5],"with":[6,168],"an":[7],"acute":[8,61],"severe":[9,62],"ulcerative":[10,63],"colitis":[11,64],"to":[12,18,28,45,69,85,88,107,114],"a":[13,19,158,175],"regional":[14,67,100,159,191],"hospital":[15,21,72,192],"are":[16],"transferred":[17,65],"metropolitan":[20,71,116,177],"for":[22,171],"specialised":[23],"care.":[24],"This":[25],"study":[26,42],"aimed":[27],"evaluate":[29],"the":[30,47,153],"outcomes":[31],"and":[32,75,146,161],"characteristics":[33],"of":[34,60,110,123,137,152],"these":[35,124,138],"patients.":[36,102,139],"METHOD:":[37],"A":[38],"retrospective":[39],"observational":[40],"cohort":[41],"was":[43,96,105,119,132,141],"conducted":[44],"examine":[46,89],"30-day":[48,93],"colectomy":[49,81,94,167,188],"rate":[50,95],"using":[51],"prospectively":[52],"collected":[53],"data":[54],"on":[55],"69":[56],"consecutive":[57],"index":[58],"cases":[59],"from":[66],"hospitals":[68],"our":[70,115],"meeting":[73],"Truelove":[74],"Witts":[76],"criteria.":[77],"Those":[78],"that":[79],"avoided":[80,120,164],"were":[82],"followed":[83],"out":[84],"1":[86,147],"year":[87],"outcomes.":[90],"RESULTS:":[91],"The":[92],"46.4%":[97],"(32/69)":[98],"in":[99,121,134,157,174,189],"transfer":[101,113,163],"Rescue":[103],"therapy":[104,156,173],"administered":[106],"65%":[108],"(45/69)":[109],"after":[112],"hospital.":[117],"Colectomy":[118,129],"55%":[122],"at":[126,143],"30":[127,144],"days.":[128],"free":[130],"status":[131],"maintained":[133],"78%":[135],"(29/39)":[136],"Mortality":[140],"0%":[142],"days":[145],"year.":[148],"CONCLUSION:":[149],"Over":[150],"50%":[151],"failing":[155],"centre":[160],"requiring":[162],"short":[165],"term":[166],"co-ordinated":[169],"referral":[170],"rescue":[172],"tertiary":[176],"inflammatory":[178],"bowel":[179],"disease":[180],"unit.":[181],"These":[182],"would":[184],"have":[185],"ultimately":[186],"required":[187],"their":[190],"without":[193],"intervention.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-10-18T00:00:00"}