{"id":"https://openalex.org/W2979178503","doi":"https://doi.org/10.2210/pdb4tpo/pdb","title":"High-resolution structure of TxtE with bound tryptophan substrate","display_name":"High-resolution structure of TxtE with bound tryptophan substrate","publication_year":2014,"publication_date":"2014-06-08","ids":{"openalex":"https://openalex.org/W2979178503","doi":"https://doi.org/10.2210/pdb4tpo/pdb","mag":"2979178503"},"language":"en","primary_location":{"id":"doi:10.2210/pdb4tpo/pdb","doi":"https://doi.org/10.2210/pdb4tpo/pdb","is_oa":false,"landing_page_url":"https://doi.org/10.2210/pdb4tpo/pdb","pdf_url":null,"source":{"id":"https://openalex.org/S7407063902","display_name":"Worldwide Protein Data Bank","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Worldwide Protein Data Bank","raw_type":"dataset"},"volume":null,"type":"dataset","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053353039","display_name":"Jackson K. B. Cahn","orcid":"https://orcid.org/0000-0001-8849-4516","observed_orcids":["https://orcid.org/0000-0001-8849-4516"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.K.B. Cahn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012048639","display_name":"Sheel C. Dodani","orcid":"https://orcid.org/0000-0003-0271-6080","observed_orcids":["https://orcid.org/0000-0003-0271-6080"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S.C. Dodani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028122252","display_name":"Sabine Brinkmann\u2010Chen","orcid":"https://orcid.org/0000-0002-5419-4192","observed_orcids":["https://orcid.org/0000-0002-5419-4192"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Brinkmann-Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005121986","display_name":"T. Heinsich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Heinsich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071409928","display_name":"John A. McIntosh","orcid":"https://orcid.org/0000-0002-9487-490X","observed_orcids":["https://orcid.org/0000-0002-9487-490X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.A. McIntosh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5043841592","display_name":"Frances H. Arnold","orcid":"https://orcid.org/0000-0002-4027-364X","observed_orcids":["https://orcid.org/0000-0002-4027-364X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F.H. Arnold","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tryptophan-biosynthesis","display_name":"tryptophan biosynthesis","score":0.8669999837875366},{"id":"https://openalex.org/keywords/tryptophan-synthase","display_name":"tryptophan synthase","score":0.8209999799728394},{"id":"https://openalex.org/keywords/protein-structure","display_name":"protein structure","score":0.5519999861717224},{"id":"https://openalex.org/keywords/enzyme-substrate-complex","display_name":"enzyme-substrate complex","score":0.6029999852180481},{"id":"https://openalex.org/keywords/aromatic-amino-acid-biosynthesis","display_name":"aromatic amino acid biosynthesis","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.544590175151825},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.46087390184402466},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4187883734703064},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3950808644294739},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3524067997932434},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.28754347562789917},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.21033623814582825},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.17882254719734192},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11863842606544495},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.10846251249313354},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2210/pdb4tpo/pdb","doi":"https://doi.org/10.2210/pdb4tpo/pdb","is_oa":false,"landing_page_url":"https://doi.org/10.2210/pdb4tpo/pdb","pdf_url":null,"source":{"id":"https://openalex.org/S7407063902","display_name":"Worldwide Protein Data Bank","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Worldwide Protein Data Bank","raw_type":"dataset"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2977726734","https://openalex.org/W6888748143","https://openalex.org/W4411145791"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-10-10T00:00:00"}