{"id":"https://openalex.org/W2978144679","doi":null,"title":"THE EFFECT OF FISH OIL ON OXIDANT/ANTIOXIDANT STATUS IN DIABETIC RATS THROUGH THE REDUCTION OF ARACHIDONIC ACID IN THE CELL MEMBRANE","display_name":"THE EFFECT OF FISH OIL ON OXIDANT/ANTIOXIDANT STATUS IN DIABETIC RATS THROUGH THE REDUCTION OF ARACHIDONIC ACID IN THE CELL MEMBRANE","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2978144679","mag":"2978144679"},"language":"en","primary_location":{"id":"mag:2978144679","doi":null,"is_oa":false,"landing_page_url":"http://www.ijppsjournal.com/Vol6Issue2/8707.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058538466","display_name":"Jihan Hussein","orcid":"https://orcid.org/0000-0002-1862-0385","observed_orcids":["https://orcid.org/0000-0002-1862-0385"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jihan Hussein","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1862-0385","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013888358","display_name":"Zakaria El-Khayat","orcid":"https://orcid.org/0000-0002-0876-7092","observed_orcids":["https://orcid.org/0000-0002-0876-7092"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zakaria El-Khayat","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0876-7092","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078197013","display_name":"Safaa Morsy","orcid":"https://orcid.org/0000-0002-5853-6145","observed_orcids":["https://orcid.org/0000-0002-5853-6145"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Safaa Morsy","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5853-6145","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034663045","display_name":"Fatma Oraby","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatma Oraby","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5075303297","display_name":"Gamal A. M. Singer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gamal A. M. Singer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6532,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.80703453,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fish-oil","display_name":"fish oil","score":0.8899999856948853},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.9900000095367432},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.925000011920929},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6660000085830688},{"id":"https://openalex.org/keywords/antioxidant-status","display_name":"antioxidant status","score":0.8130000233650208},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8539999723434448},{"id":"https://openalex.org/keywords/erythrocyte-membrane-phospholipids","display_name":"erythrocyte membrane phospholipids","score":0.9070000052452087},{"id":"https://openalex.org/keywords/8-hydroxyguanosine","display_name":"8-hydroxyguanosine","score":0.8809999823570251},{"id":"https://openalex.org/keywords/isoprostanes","display_name":"isoprostanes","score":0.8880000114440918},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9879999756813049},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.8180000185966492},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.8958107233047485},{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.8787497282028198},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5951688289642334},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5940603613853455},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5083913207054138},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4578399360179901},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.4550931453704834},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.453041136264801},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.3591299057006836},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.262553870677948},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1548578143119812},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13183382153511047},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.06547155976295471},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2978144679","doi":null,"is_oa":false,"landing_page_url":"http://www.ijppsjournal.com/Vol6Issue2/8707.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W85149963","https://openalex.org/W341193086","https://openalex.org/W1551234630","https://openalex.org/W1618818749","https://openalex.org/W1963710347","https://openalex.org/W1987420007","https://openalex.org/W1990089345","https://openalex.org/W1999848512","https://openalex.org/W2004312909","https://openalex.org/W2006485264","https://openalex.org/W2009718837","https://openalex.org/W2015090490","https://openalex.org/W2015166165","https://openalex.org/W2019837639","https://openalex.org/W2020383780","https://openalex.org/W2023943992","https://openalex.org/W2028164957","https://openalex.org/W2030409636","https://openalex.org/W2031819880","https://openalex.org/W2034921827","https://openalex.org/W2050007525","https://openalex.org/W2052664734","https://openalex.org/W2060762317","https://openalex.org/W2079818237","https://openalex.org/W2086361674","https://openalex.org/W2108258380","https://openalex.org/W2109225320","https://openalex.org/W2114589635","https://openalex.org/W2139976602","https://openalex.org/W2142720535","https://openalex.org/W2145833401","https://openalex.org/W2152311269","https://openalex.org/W2152656461","https://openalex.org/W2341666005","https://openalex.org/W2413270459","https://openalex.org/W2601676099"],"related_works":["https://openalex.org/W3013871052","https://openalex.org/W2053644769","https://openalex.org/W2291032234","https://openalex.org/W7101157618","https://openalex.org/W2731960193","https://openalex.org/W2106156891","https://openalex.org/W1992314872","https://openalex.org/W1749236681","https://openalex.org/W1969545540","https://openalex.org/W7218297372"],"abstract_inverted_index":{"Background:":[0],"Dietary":[1],"omega-3":[2],"fatty":[3],"acids":[4],"directly":[5],"affect":[6],"arachidonic":[7,55,114,148,175],"acid":[8,56,115,176],"(AA)":[9],"metabolism":[10],"because":[11],"they":[12],"displace":[13],"AA":[14],"from":[15],"membranes":[16],"and":[17,31,76,85,90,111,123,143,145],"compete":[18],"with":[19],"it":[20],"for":[21,106],"the":[22,26,39,47,52,172],"enzymes":[23],"that":[24,134],"catalyze":[25],"biosynthesis":[27],"of":[28,41,54,100,152,174],"thromboxanes,":[29],"prostaglandins":[30],"leukotrienes.":[32],"Objective:":[33],"This":[34],"study":[35,75],"aimed":[36],"to":[37],"evaluate":[38],"role":[40,169],"fish":[42,82,95,153],"oil":[43,89,96,154,164],"supplementation":[44,151,165],"in":[45,58,61,73,97,136,159,170,178,183,186],"reducing":[46],"free":[48,187],"radicals":[49,188],"production":[50],"through":[51],"reduction":[53,185],"level":[57],"erythrocyte":[59,112,124,146],"membrane":[60,113,125,147,180],"experimental":[62],"diabetic":[63,84,137],"rats.":[64],"Methods:":[65],"Forty":[66],"eight":[67],"male":[68],"albino":[69],"rats":[70,138],"were":[71,93,116,128],"used":[72],"this":[74],"divided":[77],"into":[78],"four":[79],"groups":[80,92],":control,":[81],"oil,":[83],"treated":[86,91,160],"groups.":[87],"Fish":[88,163],"administered":[94],"a":[98,184],"dose":[99],"1.2":[101],"ml":[102],"/kg":[103],"bw/day":[104],"orally":[105],"8":[107],"weeks.":[108],"Urinary":[109],"8-hydroxyguanosine":[110,142],"estimated":[117],"by":[118],"HPLC.":[119],"Also,":[120],"urinary":[121,141],"isoprostanes":[122,144],"superoxide":[126],"dismutase":[127],"determined.":[129],"Results:":[130],"Our":[131],"results":[132],"indicated":[133],"hyperglycemia":[135],"significantly":[139,155],"increased":[140],"acid,":[149],"whereas,":[150],"decreased":[156],"these":[157],"values":[158],"group.":[161],"Conclusion:":[162],"has":[166],"an":[167],"important":[168],"attenuating":[171],"elevation":[173],"(omega-6)":[177],"cell":[179],"phospholipids":[181],"resulting":[182],"production.":[189]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-10-10T00:00:00"}