{"id":"https://openalex.org/W2977985111","doi":null,"title":"The association of systemic low-grade inflammation with health-related quality of life in Finnish young men","display_name":"The association of systemic low-grade inflammation with health-related quality of life in Finnish young men","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2977985111","mag":"2977985111"},"language":"en","primary_location":{"id":"pmh:oai:jyx.jyu.fi:123456789/64767","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:NBN:fi:jyu-201906203350","pdf_url":"https://jyx.jyu.fi/bitstreams/4b7c5ed8-9b72-4638-80b9-3741e42d3b26/download","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://jyx.jyu.fi/bitstreams/4b7c5ed8-9b72-4638-80b9-3741e42d3b26/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022307063","display_name":"Mika Alho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mika Alho","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5022307063"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.18950000405311584,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.047200001776218414,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-low-grade-inflammation","display_name":"low-grade inflammation","score":0.7250000238418579},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9440000057220459},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9819999933242798},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":1.0},{"id":"https://openalex.org/keywords/rand-36","display_name":"RAND-36","score":0.8519999980926514},{"id":"https://openalex.org/keywords/cardiorespiratory-fitness","display_name":"cardiorespiratory fitness","score":0.8489999771118164},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.8709999918937683},{"id":"https://openalex.org/keywords/young-men","display_name":"young men","score":0.843999981880188},{"id":"https://openalex.org/keywords/military-reservists","display_name":"military reservists","score":0.6480000019073486},{"id":"https://openalex.org/keywords/chronic-disease-risk","display_name":"chronic disease risk","score":0.6119999885559082},{"id":"https://openalex.org/keywords/finnish-defence-forces","display_name":"Finnish Defence Forces","score":0.5130000114440918},{"id":"https://openalex.org/keywords/physical-component-summary","display_name":"physical component summary","score":0.6019999980926514},{"id":"https://openalex.org/keywords/mental-component-summary","display_name":"mental component summary","score":0.972000002861023},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.6679999828338623},{"id":"https://openalex.org/keywords/smoking-status","display_name":"smoking status","score":0.9070000052452087},{"id":"https://openalex.org/keywords/sex-differences-in-inflammation","display_name":"sex differences in inflammation","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C2776252253","wikidata":"https://www.wikidata.org/wiki/Q7663815","display_name":"Systemic inflammation","level":3,"score":0.7170143723487854},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.6251626014709473},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.47938016057014465},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47129786014556885},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3998606204986572},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2903817296028137},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2433982789516449},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:jyx.jyu.fi:123456789/64767","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:NBN:fi:jyu-201906203350","pdf_url":"https://jyx.jyu.fi/bitstreams/4b7c5ed8-9b72-4638-80b9-3741e42d3b26/download","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},{"id":"mag:2977985111","doi":null,"is_oa":false,"landing_page_url":"https://jyx.jyu.fi/bitstream/123456789/64767/1/URN%3aNBN%3afi%3ajyu-201906203350.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:jyx.jyu.fi:123456789/64767","doi":null,"is_oa":true,"landing_page_url":"http://urn.fi/URN:NBN:fi:jyu-201906203350","pdf_url":"https://jyx.jyu.fi/bitstreams/4b7c5ed8-9b72-4638-80b9-3741e42d3b26/download","source":{"id":"https://openalex.org/S4306400563","display_name":"Jyv\u00e4skyl\u00e4 University Digital Archive (University of Jyv\u00e4skyl\u00e4)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I94722563","host_organization_name":"University of Jyv\u00e4skyl\u00e4","host_organization_lineage":["https://openalex.org/I94722563"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2977985111.pdf","grobid_xml":"https://content.openalex.org/works/W2977985111.grobid-xml"},"referenced_works_count":129,"referenced_works":["https://openalex.org/W7548499","https://openalex.org/W11060070","https://openalex.org/W581977681","https://openalex.org/W1443802491","https://openalex.org/W1506603089","https://openalex.org/W1517067677","https://openalex.org/W1559641753","https://openalex.org/W1623572367","https://openalex.org/W1704362931","https://openalex.org/W1779691448","https://openalex.org/W1793390792","https://openalex.org/W1872912193","https://openalex.org/W1913207704","https://openalex.org/W1915518362","https://openalex.org/W1918432791","https://openalex.org/W1964378817","https://openalex.org/W1964548199","https://openalex.org/W1965607454","https://openalex.org/W1969703545","https://openalex.org/W1974033843","https://openalex.org/W1979058351","https://openalex.org/W1980702134","https://openalex.org/W1981851376","https://openalex.org/W1991405020","https://openalex.org/W1994014704","https://openalex.org/W1999230674","https://openalex.org/W2000054651","https://openalex.org/W2002076761","https://openalex.org/W2006389546","https://openalex.org/W2008869160","https://openalex.org/W2009412710","https://openalex.org/W2014881669","https://openalex.org/W2015128984","https://openalex.org/W2024886564","https://openalex.org/W2025550733","https://openalex.org/W2025982542","https://openalex.org/W2027117067","https://openalex.org/W2027342611","https://openalex.org/W2028776997","https://openalex.org/W2031236369","https://openalex.org/W2031811366","https://openalex.org/W2035121795","https://openalex.org/W2036632702","https://openalex.org/W2040085142","https://openalex.org/W2043458443","https://openalex.org/W2044056466","https://openalex.org/W2047922146","https://openalex.org/W2050488546","https://openalex.org/W2056574221","https://openalex.org/W2060239587","https://openalex.org/W2061252559","https://openalex.org/W2061568817","https://openalex.org/W2063868657","https://openalex.org/W2064119981","https://openalex.org/W2065201220","https://openalex.org/W2066963386","https://openalex.org/W2068194533","https://openalex.org/W2071782474","https://openalex.org/W2073229291","https://openalex.org/W2078246545","https://openalex.org/W2078378191","https://openalex.org/W2079522334","https://openalex.org/W2088940658","https://openalex.org/W2093010100","https://openalex.org/W2093845352","https://openalex.org/W2094629035","https://openalex.org/W2096166726","https://openalex.org/W2096782637","https://openalex.org/W2097195468","https://openalex.org/W2103361158","https://openalex.org/W2103488083","https://openalex.org/W2104168490","https://openalex.org/W2111923167","https://openalex.org/W2113750014","https://openalex.org/W2114280375","https://openalex.org/W2115988342","https://openalex.org/W2116784956","https://openalex.org/W2117692326","https://openalex.org/W2117884819","https://openalex.org/W2118941602","https://openalex.org/W2119316150","https://openalex.org/W2121335554","https://openalex.org/W2122259487","https://openalex.org/W2124231622","https://openalex.org/W2125921569","https://openalex.org/W2128203138","https://openalex.org/W2128759000","https://openalex.org/W2129316761","https://openalex.org/W2129785124","https://openalex.org/W2130766522","https://openalex.org/W2133045909","https://openalex.org/W2134939550","https://openalex.org/W2136759091","https://openalex.org/W2137243269","https://openalex.org/W2139186181","https://openalex.org/W2141920121","https://openalex.org/W2143390125","https://openalex.org/W2146456234","https://openalex.org/W2146858278","https://openalex.org/W2152062280","https://openalex.org/W2152377123","https://openalex.org/W2157331442","https://openalex.org/W2159030880","https://openalex.org/W2160103886","https://openalex.org/W2165334726","https://openalex.org/W2166449272","https://openalex.org/W2171605715","https://openalex.org/W2173739601","https://openalex.org/W2175474731","https://openalex.org/W2197493130","https://openalex.org/W2219897714","https://openalex.org/W2222665820","https://openalex.org/W2238144582","https://openalex.org/W2255756224","https://openalex.org/W2270954162","https://openalex.org/W2279074305","https://openalex.org/W2288948543","https://openalex.org/W2303236807","https://openalex.org/W2305285387","https://openalex.org/W2315254617","https://openalex.org/W2316376271","https://openalex.org/W2318949390","https://openalex.org/W2335592397","https://openalex.org/W2410586044","https://openalex.org/W2427968543","https://openalex.org/W2460931195","https://openalex.org/W2484881635","https://openalex.org/W2621600772","https://openalex.org/W2951829513"],"related_works":["https://openalex.org/W2121335554","https://openalex.org/W2930577892","https://openalex.org/W154476129","https://openalex.org/W2344878982","https://openalex.org/W2981944601","https://openalex.org/W2126317091","https://openalex.org/W2732577594","https://openalex.org/W2888977002","https://openalex.org/W2134939550","https://openalex.org/W7097081450"],"abstract_inverted_index":{"Background":[0],"During":[1],"the":[2,93,137,169,185,198,251,331,354],"last":[3],"two":[4],"decades,":[5],"it":[6],"has":[7,51,85],"become":[8],"evident":[9],"that":[10,83,323],"inflammatory":[11,75,90,266,278,292,316,334],"mechanisms":[12],"have":[13,71],"central":[14],"role":[15],"in":[16,98,113,143,147,209,336],"pathological":[17],"processes":[18],"of":[19,46,136,158,168,175,188,197,250,330,356],"several":[20],"chronic":[21,32],"diseases":[22,40],"such":[23],"as":[24],"type":[25],"2":[26],"diabetes,":[27],"cardiovascular":[28,67],"disease,":[29,35],"stroke,":[30],"tumorigenesis,":[31],"obstructive":[33],"pulmonary":[34],"and":[36,69,77,109,120,162,179,192,195,203,208,219,229,240,264,277,281,289,302,313,315,333,347],"Alzheimer":[37],"disease.":[38],"Chronic":[39],"tend":[41],"to":[42,269],"lower":[43],"health-related":[44],"quality":[45],"life":[47],"(HRQoL).":[48],"Low":[49],"HRQoL":[50,84,108,159],"been":[52,72,86],"associated":[53,73,87,285],"with":[54,89,287,291],"increased":[55],"mortality":[56],"risk.":[57],"Several":[58],"factors":[59],"like":[60],"age,":[61,217,300],"gender,":[62],"body":[63],"mass":[64],"index,":[65],"smoking,":[66],"fitness,":[68],"morbidities":[70],"both":[74,265,311,345],"markers":[76,267,335],"HRQoL.":[78],"There":[79,257],"is":[80,95,325],"a":[81,114,156,326,337,351],"data":[82,94],"inversely":[88],"markers,":[91],"but":[92,273,307],"very":[96],"limited":[97],"healthy,":[99,338],"young,":[100,116,340],"adult":[101,341],"population.":[102,118],"Objective":[103],"To":[104],"investigate":[105],"associations":[106],"between":[107,262,275,310,328],"systemic":[110],"low-grade":[111],"inflammation":[112],"Finnish":[115,138],"men":[117,342],"Material":[119],"Methods":[121],"Participants":[122],"(n":[123],"=":[124],"777;":[125],"mean":[126],"age":[127],"26.5":[128],"SD":[129,255],"6.8":[130],"years)":[131],"were":[132,171,182,200,206,213,231,258,284,305],"volunteered":[133],"male":[134],"reservists":[135],"Defence":[139],"Forces":[140],"who":[141],"participated":[142],"refresher":[144],"courses":[145],"organized":[146],"seven":[148],"different":[149],"garrisons":[150],"around":[151],"Finland":[152],"during":[153],"2015.":[154],"As":[155],"measure":[157],"physical":[160],"(PCS)":[161],"mental":[163],"(MCS)":[164],"component":[165],"summary":[166],"scores":[167],"RAND-36":[170,332],"calculated.":[172],"Plasma":[173],"concentrations":[174],"C-reactive":[176],"protein":[177],"(CRP)":[178],"Interleukin-6":[180],"(IL-6)":[181],"analyzed":[183],"from":[184],"blood":[186],"samples":[187],"participants.":[189],"Cardiorespiratory":[190,280],"fitness":[191,196,283],"muscle":[193,282],"strength":[194],"participants":[199,252],"measured.":[201],"Correlation":[202],"regression":[204,210,295],"analysis":[205,211,296],"performed,":[207],"there":[212,304,324],"also":[214],"adjustments":[215,298],"for":[216,225,299],"BMI":[218],"smoking-status.":[220],"Results":[221],"The":[222,319],"means":[223],"(SD)":[224],"CRP,":[226],"IL-6,":[227],"PCS,":[228],"MCS":[230,276,314],"1.15":[232],"mg/L":[233],"(1.54),":[234],"1.10":[235],"pg/L":[236],"(1.35),":[237],"54.8":[238],"(4.6),":[239],"50.9":[241],"(9.4),":[242],"respectively.":[243],"Mean":[244],"VO2max":[245],"(ml":[246],"\u00b7":[247],"kg-1\u00b7":[248],"min-1)":[249],"was":[253],"41.3":[254],"7.7.":[256],"statistically":[259],"significant":[260,308],"association":[261,309],"PCS":[263,288,312,329],"(modified":[268],"natural":[270],"logarithmic":[271],"values),":[272],"not":[274],"markers.":[279,293,317],"positively":[286],"negatively":[290],"In":[294],"after":[297],"BMI,":[301],"smoking-status,":[303],"weak":[306],"Conclusion":[318],"present":[320],"study":[321],"shows":[322],"relationship":[327],"resilient,":[339],"population,":[343],"despite":[344],"CRP":[346],"IL-6":[348],"explained":[349],"only":[350],"little":[352],"about":[353],"variance":[355],"PCS.":[357]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-10-10T00:00:00"}
