{"id":"https://openalex.org/W2977329908","doi":"https://doi.org/10.2217/cer-2019-0118","title":"If we recognize heterogeneity of treatment effect can we lessen waste?","display_name":"If we recognize heterogeneity of treatment effect can we lessen waste?","publication_year":2019,"publication_date":"2019-10-01","ids":{"openalex":"https://openalex.org/W2977329908","doi":"https://doi.org/10.2217/cer-2019-0118","mag":"2977329908","pmid":"https://pubmed.ncbi.nlm.nih.gov/31571494"},"language":"en","primary_location":{"id":"doi:10.2217/cer-2019-0118","doi":"https://doi.org/10.2217/cer-2019-0118","is_oa":false,"landing_page_url":"https://doi.org/10.2217/cer-2019-0118","pdf_url":null,"source":{"id":"https://openalex.org/S2489859990","display_name":"Journal of Comparative Effectiveness Research","issn_l":"2042-6305","issn":["2042-6305","2042-6313"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Effectiveness Research","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005567441","display_name":"Jodi B Segal","orcid":"https://orcid.org/0000-0003-3978-9662","observed_orcids":["https://orcid.org/0000-0003-3978-9662"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jodi B Segal","raw_affiliation_strings":["Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, MD, USA"],"raw_orcid":"https://orcid.org/0000-0003-3978-9662","affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073980557","display_name":"Ravi Varadhan","orcid":"https://orcid.org/0000-0002-8434-1034","observed_orcids":["https://orcid.org/0000-0002-8434-1034"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ravi Varadhan","raw_affiliation_strings":["Department of Oncology, Division of Oncology Biostatistics, Johns Hopkins University School of Medicine, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Division of Oncology Biostatistics, Johns Hopkins University School of Medicine, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":"14","first_page":"1143","last_page":"1145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10845","display_name":"Advanced Causal Inference Techniques","score":0.49729999899864197,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10845","display_name":"Advanced Causal Inference Techniques","score":0.49729999899864197,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.22269999980926514,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.11209999769926071,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/treatment-heterogeneity","display_name":"treatment effect heterogeneity","score":0.9309999942779541},{"id":"https://openalex.org/keywords/waste-reduction","display_name":"waste reduction","score":0.6930000185966492},{"id":"https://openalex.org/keywords/health-care-costs","display_name":"health care costs","score":0.5220000147819519},{"id":"https://openalex.org/keywords/health-care-utilization","display_name":"health care utilization","score":0.34700000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.911278486251831},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.40738797187805176}],"mesh":[{"descriptor_ui":"D000069342","descriptor_name":"Medical Overuse","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2217/cer-2019-0118","doi":"https://doi.org/10.2217/cer-2019-0118","is_oa":false,"landing_page_url":"https://doi.org/10.2217/cer-2019-0118","pdf_url":null,"source":{"id":"https://openalex.org/S2489859990","display_name":"Journal of Comparative Effectiveness Research","issn_l":"2042-6305","issn":["2042-6305","2042-6313"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","medline","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Effectiveness Research","raw_type":"journal-article"},{"id":"pmid:31571494","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31571494","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of comparative effectiveness research","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1616099694","https://openalex.org/W1965226098","https://openalex.org/W1968670396","https://openalex.org/W1981313494","https://openalex.org/W2001299659","https://openalex.org/W2002684552","https://openalex.org/W2004792235","https://openalex.org/W2028659545","https://openalex.org/W2031367983","https://openalex.org/W2082636434","https://openalex.org/W2117654533","https://openalex.org/W2120104507","https://openalex.org/W2135894244","https://openalex.org/W2469201213","https://openalex.org/W2554384121","https://openalex.org/W2609498601","https://openalex.org/W2784960421","https://openalex.org/W2912729689","https://openalex.org/W2948332559"],"related_works":["https://openalex.org/W2156974459","https://openalex.org/W2331830215","https://openalex.org/W2751587556","https://openalex.org/W2410775588","https://openalex.org/W7161625745","https://openalex.org/W2424862289","https://openalex.org/W2030463798","https://openalex.org/W3011522221","https://openalex.org/W1992643093","https://openalex.org/W2409577453"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-10-10T00:00:00"}