{"id":"https://openalex.org/W2975725795","doi":"https://doi.org/10.1177/0308575919856175","title":"Pathways from childhood maltreatment to cardiometabolic disease: a research review","display_name":"Pathways from childhood maltreatment to cardiometabolic disease: a research review","publication_year":2019,"publication_date":"2019-09-26","ids":{"openalex":"https://openalex.org/W2975725795","doi":"https://doi.org/10.1177/0308575919856175","mag":"2975725795"},"language":"en","primary_location":{"id":"doi:10.1177/0308575919856175","doi":"https://doi.org/10.1177/0308575919856175","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0308575919856175","pdf_url":null,"source":{"id":"https://openalex.org/S192886043","display_name":"Adoption & Fostering","issn_l":"0308-5759","issn":["0308-5759","1740-469X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adoption & Fostering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://discovery.ucl.ac.uk/10084574/3/Baldwin%20Revised%20paper%20with%20references%20cut%20clean%2020190528.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020468572","display_name":"Jessie R. Baldwin","orcid":"https://orcid.org/0000-0002-5703-5058","observed_orcids":["https://orcid.org/0000-0002-5703-5058"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jessie R Baldwin","raw_affiliation_strings":["University College London, UK; King\u2019s College London, UK","University College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University College London, UK; King\u2019s College London, UK","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I45129253"]},{"raw_affiliation_string":"University College London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064624409","display_name":"Andrea Danese","orcid":"https://orcid.org/0000-0001-8718-5412","observed_orcids":["https://orcid.org/0000-0001-8718-5412"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrea Danese","raw_affiliation_strings":["King\u2019s College London, UK; Maudsley NHS Foundation Trust, UK","King's College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King\u2019s College London, UK; Maudsley NHS Foundation Trust, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King's College London, UK","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020468572"],"corresponding_institution_ids":["https://openalex.org/I183935753","https://openalex.org/I45129253"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":3.215,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.90993123,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"43","issue":"3","first_page":"329","last_page":"339"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11380","display_name":"Child Welfare and Adoption","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3311","display_name":"Safety Research"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/child-abuse","display_name":"child abuse","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiometabolic-disease","display_name":"cardiometabolic disease","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9110000133514404},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/early-life-stress","display_name":"early life stress","score":0.8140000104904175},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.7129999995231628},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.9129999876022339},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.8299999833106995},{"id":"https://openalex.org/keywords/metabolic-changes","display_name":"metabolic changes","score":0.6520000100135803},{"id":"https://openalex.org/keywords/biological-mechanisms","display_name":"biological mechanisms","score":0.734000027179718},{"id":"https://openalex.org/keywords/prevention","display_name":"prevention","score":0.44200000166893005},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.6919999718666077}],"concepts":[{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6644998788833618},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5146051645278931},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5017328262329102},{"id":"https://openalex.org/C1691868","wikidata":"https://www.wikidata.org/wiki/Q1811049","display_name":"Life course approach","level":2,"score":0.4958523213863373},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.46987491846084595},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4266638159751892},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42270082235336304},{"id":"https://openalex.org/C2779422640","wikidata":"https://www.wikidata.org/wiki/Q3241451","display_name":"Childhood obesity","level":4,"score":0.4215797185897827},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.4110136926174164},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.30092835426330566},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.26041868329048157},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.191920667886734},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.10482719540596008},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09616687893867493}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1177/0308575919856175","doi":"https://doi.org/10.1177/0308575919856175","is_oa":false,"landing_page_url":"https://doi.org/10.1177/0308575919856175","pdf_url":null,"source":{"id":"https://openalex.org/S192886043","display_name":"Adoption & Fostering","issn_l":"0308-5759","issn":["0308-5759","1740-469X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Adoption & Fostering","raw_type":"journal-article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10084574","doi":null,"is_oa":true,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10084574/","pdf_url":"https://discovery.ucl.ac.uk/10084574/3/Baldwin%20Revised%20paper%20with%20references%20cut%20clean%2020190528.pdf","source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Adoption and Fostering , 43 (3) pp. 329-339. (2019)","raw_type":"Article"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/494b05ea-a0e7-4662-b456-cd49adc36574","doi":null,"is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/494b05ea-a0e7-4662-b456-cd49adc36574","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Baldwin, J R & Danese, A 2019, 'Pathways from childhood maltreatment to cardiometabolic disease : a research review', Adoption and Fostering, vol. 43, no. 3, pp. 329-339. https://doi.org/10.1177/0308575919856175","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:10084574","doi":null,"is_oa":true,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/10084574/","pdf_url":"https://discovery.ucl.ac.uk/10084574/3/Baldwin%20Revised%20paper%20with%20references%20cut%20clean%2020190528.pdf","source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Adoption and Fostering , 43 (3) pp. 329-339. (2019)","raw_type":"Article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2975725795.pdf","grobid_xml":"https://content.openalex.org/works/W2975725795.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W758061270","https://openalex.org/W1584609572","https://openalex.org/W1917557935","https://openalex.org/W1965376635","https://openalex.org/W1969157069","https://openalex.org/W1981500982","https://openalex.org/W1982560399","https://openalex.org/W1997319865","https://openalex.org/W2006656085","https://openalex.org/W2011914193","https://openalex.org/W2014932112","https://openalex.org/W2026340830","https://openalex.org/W2028744383","https://openalex.org/W2038714501","https://openalex.org/W2048695945","https://openalex.org/W2062221375","https://openalex.org/W2066181843","https://openalex.org/W2074469151","https://openalex.org/W2077730504","https://openalex.org/W2077940341","https://openalex.org/W2078858790","https://openalex.org/W2084060129","https://openalex.org/W2093500882","https://openalex.org/W2101746144","https://openalex.org/W2101843129","https://openalex.org/W2106097361","https://openalex.org/W2116839388","https://openalex.org/W2118488543","https://openalex.org/W2118811485","https://openalex.org/W2122192348","https://openalex.org/W2123930268","https://openalex.org/W2126795224","https://openalex.org/W2129399398","https://openalex.org/W2130495917","https://openalex.org/W2131285266","https://openalex.org/W2134808712","https://openalex.org/W2135402241","https://openalex.org/W2137399866","https://openalex.org/W2138555445","https://openalex.org/W2148628462","https://openalex.org/W2154374425","https://openalex.org/W2159691606","https://openalex.org/W2165277160","https://openalex.org/W2166400079","https://openalex.org/W2168007306","https://openalex.org/W2271144139","https://openalex.org/W2316376271","https://openalex.org/W2501801755","https://openalex.org/W2731708538","https://openalex.org/W2753286321","https://openalex.org/W2780541235","https://openalex.org/W2938440002","https://openalex.org/W3124893731"],"related_works":["https://openalex.org/W2923913791","https://openalex.org/W3024352503","https://openalex.org/W2554092752","https://openalex.org/W4391714369","https://openalex.org/W2518826056","https://openalex.org/W4282934301","https://openalex.org/W2606573611","https://openalex.org/W2780541235","https://openalex.org/W4414866687","https://openalex.org/W2901342547"],"abstract_inverted_index":{"Childhood":[0],"maltreatment":[1,42],"is":[2,33],"a":[3],"risk":[4,71,83],"factor":[5],"for":[6],"poor":[7],"physical":[8,143],"health":[9],"outcomes":[10],"in":[11,55,67,86,92,134],"later":[12,133],"life,":[13,135],"such":[14],"as":[15,144,146],"cardiovascular":[16],"disease":[17,75,132],"and":[18,61,88,94,121,138],"type":[19],"2":[20],"diabetes.":[21],"In":[22],"order":[23],"to":[24,28,35,43,59],"target":[25],"preventive":[26],"interventions":[27],"reduce":[29],"this":[30],"risk,":[31],"it":[32],"important":[34],"understand":[36],"the":[37,62,70,112],"biological":[38,56],"mechanisms":[39],"linking":[40],"childhood":[41],"cardiometabolic":[44,74,131],"disorders.":[45],"Research":[46],"reviewed":[47],"here":[48],"suggests":[49],"that":[50],"maltreated":[51,78,127],"children":[52,79,128],"show":[53,80],"alterations":[54],"systems":[57],"relating":[58],"metabolism":[60],"immune":[63,122],"system":[64],"which":[65],"could,":[66],"turn,":[68],"increase":[69],"of":[72,84,101,115],"long-term":[73],"risk.":[76],"Specifically,":[77],"an":[81],"elevated":[82],"obesity":[85,120],"adulthood":[87],"greater":[89],"inflammation":[90],"levels":[91],"adolescence":[93],"adulthood.":[95],"These":[96],"findings":[97],"from":[98,107,129],"observational":[99],"studies":[100],"humans":[102],"are":[103],"consistent":[104],"with":[105],"evidence":[106],"experimental":[108],"animal":[109],"models":[110],"showing":[111],"causal":[113],"effects":[114],"early":[116],"life":[117],"stress":[118],"on":[119,142],"function.":[123],"To":[124],"help":[125],"prevent":[126],"developing":[130],"clinical":[136],"assessment":[137],"treatment":[139],"should":[140],"focus":[141],"well":[145],"mental":[147],"health.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2019-10-03T00:00:00"}