{"id":"https://openalex.org/W2974227283","doi":"https://doi.org/10.1001/jamanetworkopen.2019.11426","title":"Association of Timing of Adverse Childhood Experiences and Caregiver Support With Regionally Specific Brain Development in Adolescents","display_name":"Association of Timing of Adverse Childhood Experiences and Caregiver Support With Regionally Specific Brain Development in Adolescents","publication_year":2019,"publication_date":"2019-09-18","ids":{"openalex":"https://openalex.org/W2974227283","doi":"https://doi.org/10.1001/jamanetworkopen.2019.11426","mag":"2974227283","pmid":"https://pubmed.ncbi.nlm.nih.gov/31532514","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6751767"},"language":"en","primary_location":{"id":"doi:10.1001/jamanetworkopen.2019.11426","doi":"https://doi.org/10.1001/jamanetworkopen.2019.11426","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2019.11426","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2751389/luby_2019_oi_190446.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2751389/luby_2019_oi_190446.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014800788","display_name":"Joan L. Luby","orcid":"https://orcid.org/0000-0001-5352-1721","observed_orcids":["https://orcid.org/0000-0001-5352-1721"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joan L. Luby","raw_affiliation_strings":["Department of Psychiatry (Child), School of Medicine, Washington University in St Louis, St Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry (Child), School of Medicine, Washington University in St Louis, St Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051921038","display_name":"Rebecca Tillman","orcid":"https://orcid.org/0000-0002-7472-4971","observed_orcids":["https://orcid.org/0000-0002-7472-4971"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca Tillman","raw_affiliation_strings":["Department of Psychiatry, School of Medicine, Washington University in St Louis, St Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, School of Medicine, Washington University in St Louis, St Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026517414","display_name":"Deanna M. Barch","orcid":"https://orcid.org/0000-0003-1693-8506","observed_orcids":["https://orcid.org/0000-0003-1693-8506"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deanna M. Barch","raw_affiliation_strings":["Department of Psychiatry, School of Medicine, Washington University in St Louis, St Louis, Missouri","Department of Psychological and Brain Sciences, Washington University in St Louis, St Louis, Missouri"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, School of Medicine, Washington University in St Louis, St Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Psychological and Brain Sciences, Washington University in St Louis, St Louis, Missouri","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014800788"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":13.1297,"has_fulltext":true,"cited_by_count":97,"citation_normalized_percentile":{"value":0.99174477,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"2","issue":"9","first_page":"e1911426","last_page":"e1911426"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11380","display_name":"Child Welfare and Adoption","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3311","display_name":"Safety Research"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adverse-childhood-experiences","display_name":"adverse childhood experiences","score":0.996999979019165},{"id":"https://openalex.org/keywords/caregiver-support","display_name":"caregiver support","score":0.8339999914169312},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.597000002861023},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7310000061988831},{"id":"https://openalex.org/keywords/amygdala","display_name":"amygdala","score":1.0},{"id":"https://openalex.org/keywords/caudate-nucleus","display_name":"caudate nucleus","score":0.7480000257492065},{"id":"https://openalex.org/keywords/subgenual-cingulate","display_name":"subgenual cingulate","score":0.8740000128746033},{"id":"https://openalex.org/keywords/insular-cortex","display_name":"insula","score":0.9940000176429749},{"id":"https://openalex.org/keywords/limbic-system","display_name":"limbic system","score":0.7260000109672546},{"id":"https://openalex.org/keywords/striatum","display_name":"striatum","score":0.9079999923706055},{"id":"https://openalex.org/keywords/buffering-hypothesis","display_name":"buffering hypothesis","score":0.8529999852180481},{"id":"https://openalex.org/keywords/middle-childhood","display_name":"middle childhood","score":0.5109999775886536},{"id":"https://openalex.org/keywords/adolescence","display_name":"adolescence","score":0.984000027179718},{"id":"https://openalex.org/keywords/regional-specificity","display_name":"regional specificity","score":0.4950000047683716},{"id":"https://openalex.org/keywords/depressive-symptoms","display_name":"depressive symptoms","score":0.48100000619888306},{"id":"https://openalex.org/keywords/prevention","display_name":"prevention","score":0.6759999990463257},{"id":"https://openalex.org/keywords/daycare-centers","display_name":"daycare centers","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C104996578","wikidata":"https://www.wikidata.org/wiki/Q827617","display_name":"Insula","level":2,"score":0.637074887752533},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5691107511520386},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5353840589523315},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.5130009055137634},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48105528950691223},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4570058584213257},{"id":"https://openalex.org/C2777082460","wikidata":"https://www.wikidata.org/wiki/Q3377398","display_name":"Early childhood","level":2,"score":0.4251560568809509},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.413241982460022},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4109841287136078},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.37307628989219666},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.3597392439842224},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2534109354019165},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.10759761929512024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10208848118782043},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000067697","descriptor_name":"Adolescent Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000076783","descriptor_name":"Adverse Childhood Experiences","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000679","descriptor_name":"Amygdala","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002657","descriptor_name":"Child Development","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008923","descriptor_name":"Missouri","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012944","descriptor_name":"Social Support","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D017028","descriptor_name":"Caregivers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1001/jamanetworkopen.2019.11426","doi":"https://doi.org/10.1001/jamanetworkopen.2019.11426","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2019.11426","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2751389/luby_2019_oi_190446.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6751767","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6751767","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Netw Open","raw_type":"Text"},{"id":"pmid:31532514","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31532514","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA network open","raw_type":"Journal Article"},{"id":"pmh:oai:digitalcommons.wustl.edu:open_access_pubs-9869","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.wustl.edu/open_access_pubs/8863","pdf_url":"https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=9869&context=open_access_pubs","source":{"id":"https://openalex.org/S4306400764","display_name":"Digital Commons@Becker (Washington University School of Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204465549","host_organization_name":"Washington University in St. Louis","host_organization_lineage":["https://openalex.org/I204465549"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Open Access Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1001/jamanetworkopen.2019.11426","doi":"https://doi.org/10.1001/jamanetworkopen.2019.11426","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2019.11426","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2751389/luby_2019_oi_190446.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G9000881653","display_name":"Developmental Pathways to Borderline Personality Disorder: Longitudinal Observational, Clinical, and Neural Predictors From Early Childhood to Young Adulthood","funder_award_id":"R01MH090786","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2974227283.pdf","grobid_xml":"https://content.openalex.org/works/W2974227283.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1108352418","https://openalex.org/W1855665873","https://openalex.org/W1890675559","https://openalex.org/W1896909820","https://openalex.org/W1977419693","https://openalex.org/W1982041899","https://openalex.org/W1999889452","https://openalex.org/W2007581301","https://openalex.org/W2010878835","https://openalex.org/W2018031501","https://openalex.org/W2053041505","https://openalex.org/W2069735923","https://openalex.org/W2091574708","https://openalex.org/W2103481737","https://openalex.org/W2106915081","https://openalex.org/W2127914548","https://openalex.org/W2134144143","https://openalex.org/W2134744704","https://openalex.org/W2152293970","https://openalex.org/W2159252734","https://openalex.org/W2159772210","https://openalex.org/W2164355830","https://openalex.org/W2213415910","https://openalex.org/W2300556435","https://openalex.org/W2343259514","https://openalex.org/W2507387536","https://openalex.org/W2523665179","https://openalex.org/W2532661409","https://openalex.org/W2650764880","https://openalex.org/W2776467999","https://openalex.org/W2944382100","https://openalex.org/W2944831240","https://openalex.org/W2949900545","https://openalex.org/W4240488350","https://openalex.org/W4251864300","https://openalex.org/W4255813262"],"related_works":["https://openalex.org/W4206782390","https://openalex.org/W4302303772","https://openalex.org/W3005160856","https://openalex.org/W7213400104","https://openalex.org/W7127400814","https://openalex.org/W2766229616","https://openalex.org/W4414383664","https://openalex.org/W4400034805","https://openalex.org/W4411145269","https://openalex.org/W7131415718"],"abstract_inverted_index":{"Importance:":[0],"Few":[1],"data":[2,222,234,247,256],"are":[3,365],"available":[4,224,249],"to":[5,29,54,118,145],"inform":[6,30,383],"the":[7,12,38,44,92,99,162,263,275,284,287,318,325,352,355,384,393],"associations":[8,13,350,368],"and":[9,18,40,51,59,66,70,81,89,151,156,168,176,182,185,191,231,253,267,280,283,295,340,358,371,386],"timing":[10,23,39,385],"of":[11,22,43,57,107,131,159,161,173,187,197,202,262,277,286,320,327,354,369,389,395],"between":[14,46,265,274],"adversity,":[15],"caregiver":[16,52,178,311],"support,":[17],"brain":[19,61,375],"outcomes.":[20,398],"Consideration":[21],"has":[24],"important":[25,377],"public":[26],"health":[27],"implications":[28],"more":[31,314],"precise":[32],"prevention":[33],"strategies.":[34],"Objective:":[35],"To":[36],"evaluate":[37],"regional":[41,367],"specificity":[42],"association":[45,264,273],"adverse":[47],"childhood":[48,65],"experiences":[49],"(ACEs)":[50],"support":[53,179,233,255,268,282,312,341,370],"structural":[55],"development":[56,285,319,353],"limbic":[58],"striatal":[60],"regions":[62,322],"in":[63,91,154,324],"middle":[64],"adolescence.":[67],"Design,":[68],"Setting,":[69],"Participants:":[71],"This":[72],"15-year":[73],"developmental,":[74],"neuroimaging":[75,108],"cohort":[76,123],"study":[77],"included":[78],"211":[79,203],"children":[80,204,227,252],"their":[82],"caregivers":[83],"screened":[84],"from":[85,114,141],"day":[86],"care":[87],"centers":[88],"preschools":[90],"St":[93],"Louis,":[94],"Missouri,":[95],"metropolitan":[96],"area":[97],"during":[98,170,194],"preschool":[100,181,214,278,332],"period,":[101],"with":[102,128,271,317,351,373],"an":[103,272],"additional":[104],"4":[105,171,195],"waves":[106,172,196],"at":[109,180,209,238],"school":[110,183,239],"age":[111,240],"through":[112],"adolescence":[113,155],"November":[115],"14,":[116],"2007,":[117],"August":[119],"29,":[120],"2017.":[121],"The":[122,360],"was":[124,139,306,313],"oversampled":[125],"for":[126,225,235,250,257,378,392],"preschoolers":[127],"elevated":[129],"symptoms":[130],"depression":[132],"using":[133],"a":[134],"brief":[135],"screener.":[136],"Data":[137],"analysis":[138],"performed":[140],"March":[142],"19,":[143],"2019,":[144],"July":[146],"26,":[147],"2019.":[148],"Main":[149],"Outcomes":[150],"Measures:":[152],"Volumes":[153],"developmental":[157,397],"trajectories":[158],"volumes":[160,186],"amygdala,":[163,188],"hippocampus,":[164,189],"caudate,":[165],"subgenual":[166,192],"cingulate,":[167],"insula":[169],"scanning;":[174],"ACEs":[175,266,279,333],"observed":[177],"age;":[184],"insula,":[190],"cingulate":[193],"scanning.":[198],"Results:":[199],"A":[200,303],"total":[201],"(107":[205],"[50.7%]":[206],"male)":[207,230],"completed":[208],"least":[210],"1":[211],"scan.":[212],"At":[213],"(mean":[215,241],"[SD]":[216],"age,":[217],"5.5":[218],"[0.8]":[219],"years),":[220,245],"ACE":[221,246],"were":[223,248,269],"164":[226],"(84":[228],"[51.2%]":[229],"maternal":[232,254],"155":[236],"children;":[237],"[SD],":[242],"8.3":[243],"[1.2]":[244],"172":[251],"146":[258],"children.":[259],"Unique":[260],"patterns":[261],"found,":[270],"interaction":[276],"school-age":[281],"hippocampus":[288],"(t":[289,297,334,342],"=":[290,293,298,301,335,338,343,346],"-2.27;":[291],"P":[292,300,337,345],".02)":[294,339],"amygdala":[296],"-2.12;":[299],".04).":[302],"buffering":[304],"hypothesis":[305],"not":[307],"confirmed":[308],"because":[309],"high":[310],"strongly":[315],"associated":[316],"these":[321],"only":[323],"context":[326],"low":[328],"ACEs.":[329],"In":[330],"contrast,":[331],"-2.30;":[336],"2.59;":[344],".01)":[347],"had":[348],"independent":[349],"caudate.":[356],"Conclusions":[357],"Relevance:":[359],"findings":[361],"suggest":[362],"that":[363],"there":[364],"unique":[366],"adversity":[372],"key":[374],"structures":[376],"emotional":[379],"regulation.":[380],"Results":[381],"may":[382],"potential":[387],"targets":[388],"preventive":[390],"action":[391],"range":[394],"poor":[396]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-09-26T00:00:00"}