{"id":"https://openalex.org/W2973154392","doi":"https://doi.org/10.1161/strokeaha.119.026143","title":"Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile","display_name":"Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile","publication_year":2019,"publication_date":"2019-09-12","ids":{"openalex":"https://openalex.org/W2973154392","doi":"https://doi.org/10.1161/strokeaha.119.026143","mag":"2973154392","pmid":"https://pubmed.ncbi.nlm.nih.gov/31510897"},"language":"en","primary_location":{"id":"doi:10.1161/strokeaha.119.026143","doi":"https://doi.org/10.1161/strokeaha.119.026143","is_oa":false,"landing_page_url":"https://doi.org/10.1161/strokeaha.119.026143","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6817410","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021022648","display_name":"Babak Benjamin Navi","orcid":"https://orcid.org/0000-0001-8424-6128","observed_orcids":["https://orcid.org/0000-0001-8424-6128"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Babak B. Navi","raw_affiliation_strings":["Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","institution_ids":[]},{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050126514","display_name":"Ryna Mathias","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryna Mathias","raw_affiliation_strings":["From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","Ryna Mathias From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Ryna Mathias From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020774404","display_name":"Carla Pisarro Sherman","orcid":"https://orcid.org/0000-0003-4800-0061","observed_orcids":["https://orcid.org/0000-0003-4800-0061"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carla P. Sherman","raw_affiliation_strings":["From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","Carla P. Sherman From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Carla P. Sherman From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Julia Wolfe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia Wolfe","raw_affiliation_strings":["Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","Julia Wolfe Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","institution_ids":[]},{"raw_affiliation_string":"Julia Wolfe Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064975333","display_name":"Hooman Kamel","orcid":"https://orcid.org/0000-0002-5745-0307","observed_orcids":["https://orcid.org/0000-0002-5745-0307"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hooman Kamel","raw_affiliation_strings":["From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","Hooman Kamel From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Hooman Kamel From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007663088","display_name":"Scott T. Tagawa","orcid":"https://orcid.org/0000-0003-2777-8587","observed_orcids":["https://orcid.org/0000-0003-2777-8587"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott T. Tagawa","raw_affiliation_strings":["Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","Scott T. Tagawa Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Scott T. Tagawa Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075739031","display_name":"Ashish Saxena","orcid":"https://orcid.org/0000-0003-3353-129X","observed_orcids":["https://orcid.org/0000-0003-3353-129X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashish Saxena","raw_affiliation_strings":["Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","Ashish Saxena Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Ashish Saxena Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049924653","display_name":"Allyson J. Ocean","orcid":"https://orcid.org/0000-0003-3799-9527","observed_orcids":["https://orcid.org/0000-0003-3799-9527"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allyson J. Ocean","raw_affiliation_strings":["Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","Allyson J. Ocean Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Allyson J. Ocean Department of Medicine (S.T.T., A.S., A.J.O.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010768101","display_name":"Costantino Iadecola","orcid":"https://orcid.org/0000-0001-9797-073X","observed_orcids":["https://orcid.org/0000-0001-9797-073X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Costantino Iadecola","raw_affiliation_strings":["From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","Costantino Iadecola From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Costantino Iadecola From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004573264","display_name":"Lisa Marie DeAngelis","orcid":"https://orcid.org/0000-0002-6290-7818","observed_orcids":["https://orcid.org/0000-0002-6290-7818"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. DeAngelis","raw_affiliation_strings":["Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","Lisa M. DeAngelis From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","institution_ids":[]},{"raw_affiliation_string":"From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Lisa M. DeAngelis From the Department of Neurology and Feil Family Brain and Mind Research Institute (B.B.N, R.M., C.P.S., H.K., C.I., L.M.D.), Weill Cornell Medicine, New York, NY Department of Neurology, Memorial Sloan Kettering, New York, NY (B.B.N, J.W., L.M.D.)","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113514048","display_name":"Mitchell S.V. Elkind","orcid":"https://orcid.org/0000-0003-2562-1156","observed_orcids":["https://orcid.org/0000-0003-2562-1156"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell S.V. Elkind","raw_affiliation_strings":["Departments of Neurology (M.S.V.E.), Columbia University, New York, NY","Epidemiology (M.S.V.E.), Columbia University, New York, NY","Mitchell S.V. Elkind Departments of Neurology (M.S.V.E.), Columbia University, New York, NY Epidemiology (M.S.V.E.), Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Neurology (M.S.V.E.), Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Epidemiology (M.S.V.E.), Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Mitchell S.V. Elkind Departments of Neurology (M.S.V.E.), Columbia University, New York, NY Epidemiology (M.S.V.E.), Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108829685","display_name":"Heather Hull","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Hull","raw_affiliation_strings":["Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","Heather Hull Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Heather Hull Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088465643","display_name":"Glen C. Jickling","orcid":"https://orcid.org/0000-0003-3543-0820","observed_orcids":["https://orcid.org/0000-0003-3543-0820"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Glen C. Jickling","raw_affiliation_strings":["Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","Glen C. Jickling Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Glen C. Jickling Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021502220","display_name":"Frank R. Sharp","orcid":"https://orcid.org/0000-0002-5642-1459","observed_orcids":["https://orcid.org/0000-0002-5642-1459"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank R. Sharp","raw_affiliation_strings":["Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","Frank R. Sharp Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Frank R. Sharp Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081051831","display_name":"Bradley P. Ander","orcid":"https://orcid.org/0000-0003-2320-7920","observed_orcids":["https://orcid.org/0000-0003-2320-7920"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradley P. Ander","raw_affiliation_strings":["Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","Bradley P. Ander Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Bradley P. Ander Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015949085","display_name":"Boryana S. Stamova","orcid":"https://orcid.org/0000-0002-5440-8816","observed_orcids":["https://orcid.org/0000-0002-5440-8816"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Boryana Stamova","raw_affiliation_strings":["Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","Boryana Stamova Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Boryana Stamova Department of Neurology, University of California, Davis (H.H., G.C.J., F.R.S., B.P.A., B.S.)","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4877,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.82248053,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"50","issue":"11","first_page":"3259","last_page":"3264"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10510","display_name":"Stroke Rehabilitation and Recovery","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-ischemic-stroke","display_name":"acute ischemic stroke","score":0.9570000171661377},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.675000011920929},{"id":"https://openalex.org/keywords/cryptogenic-stroke","display_name":"cryptogenic stroke","score":0.8610000014305115},{"id":"https://openalex.org/keywords/autophagy-signaling-pathways","display_name":"autophagy signaling","score":0.9330000281333923},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/p62","display_name":"p62","score":0.7310000061988831},{"id":"https://openalex.org/keywords/creb1","display_name":"CREB1","score":0.9269999861717224},{"id":"https://openalex.org/keywords/interferon","display_name":"interferon","score":0.5450000166893005},{"id":"https://openalex.org/keywords/interleukin-1","display_name":"interleukin-1","score":0.7900000214576721},{"id":"https://openalex.org/keywords/mtor-signaling","display_name":"mTOR signaling","score":0.7450000047683716},{"id":"https://openalex.org/keywords/occult-cancer-detection","display_name":"occult cancer detection","score":0.875}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8485249876976013},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.7408350110054016},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7080923318862915},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5077889561653137},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.47233596444129944},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.353661447763443},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3299523591995239},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09793421626091003},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002545","descriptor_name":"Brain Ischemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012334","descriptor_name":"RNA, Neoplasm","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1161/strokeaha.119.026143","doi":"https://doi.org/10.1161/strokeaha.119.026143","is_oa":false,"landing_page_url":"https://doi.org/10.1161/strokeaha.119.026143","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"},{"id":"pmid:31510897","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31510897","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"Clinical Trial"},{"id":"pmh:oai:pubmedcentral.nih.gov:6817410","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6817410","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stroke","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6817410","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6817410","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stroke","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8299999833106995}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2302313662","display_name":null,"funder_award_id":"R01NS106950","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G2708783064","display_name":null,"funder_award_id":"R01NS097000","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6446405958","display_name":"Cancer And Risk Of Ischemic Stroke","funder_award_id":"K23NS091395","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W2004630197","https://openalex.org/W2011121262","https://openalex.org/W2019716616","https://openalex.org/W2035320411","https://openalex.org/W2051979907","https://openalex.org/W2120211376","https://openalex.org/W2555300784","https://openalex.org/W2567715867","https://openalex.org/W2591708623","https://openalex.org/W2798052076","https://openalex.org/W2805669408","https://openalex.org/W2906175764"],"related_works":["https://openalex.org/W2460041365","https://openalex.org/W2186113122","https://openalex.org/W1523310174","https://openalex.org/W2531913951","https://openalex.org/W2811135594","https://openalex.org/W2500702315","https://openalex.org/W4302381976","https://openalex.org/W4243634448","https://openalex.org/W2916797227","https://openalex.org/W2155562423"],"abstract_inverted_index":{"Background":[0],"and":[1,62,64,83,97,116,122,144,189,210,225],"Purpose-":[2],"Comorbid":[3],"cancer":[4,61,70,98,264],"is":[5],"common":[6],"in":[7,80,90,103,113,206,242,265],"patients":[8,248,266],"with":[9,57,68,249,267],"acute":[10],"ischemic":[11],"stroke":[12],"(AIS).":[13],"As":[14],"blood":[15,243,257],"mRNA":[16,141,244,258],"profiles":[17,246],"can":[18,259],"distinguish":[19,178],"AIS":[20,26,63,72],"mechanisms,":[21],"we":[22],"hypothesized":[23],"that":[24,176],"cancer-related":[25,250],"would":[27],"have":[28],"a":[29,238],"distinctive":[30,239],"gene":[31,156,211],"expression":[32,157,245],"profile.":[33],"Methods-":[34],"We":[35],"evaluated":[36],"4":[37],"groups":[38,67,85,118,171],"of":[39,55,166,202,220,247,262],"10":[40],"subjects":[41,89,112],"prospectively":[42],"enrolled":[43],"at":[44],"3":[45,65],"centers":[46],"from":[47],"2009":[48],"to":[49,88,111,130,153,185],"2018.":[50],"This":[51,233],"included":[52],"the":[53,81,91,104,114,162,182,186],"group":[54,93,108,184,188],"interest":[56],"active":[58,69],"solid":[59],"tumor":[60],"control":[66],"only,":[71,73],"or":[74],"vascular":[75,105,123],"risk":[76,106,124],"factors":[77],"only.":[78],"Subjects":[79,102],"AIS-only":[82],"cancer-only":[84,193],"were":[86,109,151,168,197],"matched":[87,110],"cancer-stroke":[92,115,163,183],"by":[94,119],"age,":[95,120],"sex,":[96,121],"type":[99],"(if":[100],"applicable).":[101],"factor":[107],"stroke-only":[117,187],"factors.":[125],"Blood":[126],"was":[127,137],"drawn":[128],"72":[129],"120":[131],"hours":[132],"after":[133,190],"stroke.":[134],"Total":[135],"RNA":[136],"processed":[138],"using":[139],"3'":[140],"sequencing.":[142],"ANOVA":[143],"Fisher":[145],"least":[146],"significant":[147],"difference":[148],"contrast":[149],"methods":[150],"used":[152],"estimate":[154],"differential":[155],"between":[158],"groups.":[159],"Results-":[160],"In":[161],"group,":[164],"50%":[165],"strokes":[167],"cryptogenic.":[169],"All":[170],"had":[172],"differentially":[173,198],"expressed":[174],"genes":[175,196],"could":[177],"among":[179],"them.":[180],"Comparing":[181],"accounting":[191],"for":[192,237],"genes,":[194],"438":[195],"expressed,":[199],"including":[200,213],"upregulation":[201],"multiple":[203],"genes/pathways":[204],"implicated":[205],"autophagy":[207],"signaling,":[208,222],"immunity/inflammation,":[209],"regulation,":[212],"IL":[214],"(interleukin)-1,":[215],"interferon,":[216],"relaxin,":[217],"mammalian":[218],"target":[219],"rapamycin":[221],"SQSTMI1":[223],"(sequestosome-1),":[224],"CREB1":[226],"(cAMP":[227],"response":[228],"element":[229],"binding":[230],"protein-1).":[231],"Conclusions-":[232],"study":[234],"provides":[235],"evidence":[236],"molecular":[240],"signature":[241],"AIS.":[251,268],"Future":[252],"studies":[253],"should":[254],"evaluate":[255],"whether":[256],"predict":[260],"detection":[261],"occult":[263],"Clinical":[269],"Trial":[270],"Registration-":[271],"URL:":[272],"https://clinicaltrials.gov.":[273],"Unique":[274],"identifier:":[275],"NCT02604667.":[276]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}