{"id":"https://openalex.org/W2971408331","doi":"https://doi.org/10.7196/samj.2019.v109i9.13936","title":"Role of family history and clinical screening in the identification of families with idiopathic dilated cardiomyopathy in Johannesburg, South Africa","display_name":"Role of family history and clinical screening in the identification of families with idiopathic dilated cardiomyopathy in Johannesburg, South Africa","publication_year":2019,"publication_date":"2019-08-28","ids":{"openalex":"https://openalex.org/W2971408331","doi":"https://doi.org/10.7196/samj.2019.v109i9.13936","mag":"2971408331","pmid":"https://pubmed.ncbi.nlm.nih.gov/31635593"},"language":"en","primary_location":{"id":"doi:10.7196/samj.2019.v109i9.13936","doi":"https://doi.org/10.7196/samj.2019.v109i9.13936","is_oa":true,"landing_page_url":"https://doi.org/10.7196/samj.2019.v109i9.13936","pdf_url":"http://www.samj.org.za/index.php/samj/article/download/12695/8948","source":{"id":"https://openalex.org/S147026946","display_name":"South African Medical Journal","issn_l":"0256-9574","issn":["0256-9574","2078-5135"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["dhet","doaj","dongbi-c","doyens","jpps-2","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315351","host_organization_name":"Health and Medical Publishing Group","host_organization_lineage":["https://openalex.org/P4310315351"],"host_organization_lineage_names":["Health and Medical Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.samj.org.za/index.php/samj/article/download/12695/8948","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110007739","display_name":"C. Bailly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107920810","display_name":"National Health Laboratory Service","ror":"https://ror.org/00znvbk37","country_code":"ZA","type":"government","lineage":["https://openalex.org/I107920810"]},{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"C Bailly","raw_affiliation_strings":["Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. claudedidierbailly@gmail.com","Division of Human Genetics, National Health Laboratory Service","School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. claudedidierbailly@gmail.com","institution_ids":["https://openalex.org/I107920810","https://openalex.org/I192619145"]},{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service","institution_ids":["https://openalex.org/I107920810"]},{"raw_affiliation_string":"School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003759807","display_name":"Sasha Henriques","orcid":"https://orcid.org/0009-0008-0422-6468","observed_orcids":["https://orcid.org/0009-0008-0422-6468"]},"institutions":[{"id":"https://openalex.org/I107920810","display_name":"National Health Laboratory Service","ror":"https://ror.org/00znvbk37","country_code":"ZA","type":"government","lineage":["https://openalex.org/I107920810"]},{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"S Henriques","raw_affiliation_strings":["Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","Division of Human Genetics, National Health Laboratory Service","School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I107920810","https://openalex.org/I192619145"]},{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service","institution_ids":["https://openalex.org/I107920810"]},{"raw_affiliation_string":"School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057484270","display_name":"Nqoba Tsabedze","orcid":"https://orcid.org/0000-0002-7210-1447","observed_orcids":["https://orcid.org/0000-0002-7210-1447"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"N Tsabedze","raw_affiliation_strings":["Division of Cardiology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040897428","display_name":"Amanda Krause","orcid":"https://orcid.org/0000-0002-7157-0807","observed_orcids":["https://orcid.org/0000-0002-7157-0807"]},"institutions":[{"id":"https://openalex.org/I107920810","display_name":"National Health Laboratory Service","ror":"https://ror.org/00znvbk37","country_code":"ZA","type":"government","lineage":["https://openalex.org/I107920810"]},{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"A Krause","raw_affiliation_strings":["Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","Division of Human Genetics, National Health Laboratory Service","School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service; and School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I107920810","https://openalex.org/I192619145"]},{"raw_affiliation_string":"Division of Human Genetics, National Health Laboratory Service","institution_ids":["https://openalex.org/I107920810"]},{"raw_affiliation_string":"School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa","institution_ids":["https://openalex.org/I192619145"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5732,"currency":"ZAR","value_usd":311},"apc_paid":{"value":5732,"currency":"ZAR","value_usd":311},"fwci":0.1793,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.52940278,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"109","issue":"9","first_page":"673","last_page":"673"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-dilated-cardiomyopathy","display_name":"idiopathic dilated cardiomyopathy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/familial-dilated-cardiomyopathy","display_name":"familial dilated cardiomyopathy","score":0.9559999704360962},{"id":"https://openalex.org/keywords/family-history-medicine","display_name":"family history (medicine)","score":0.9319999814033508},{"id":"https://openalex.org/keywords/family-screening","display_name":"family screening","score":0.6930000185966492},{"id":"https://openalex.org/keywords/pedigree-analysis","display_name":"pedigree analysis","score":0.656000018119812},{"id":"https://openalex.org/keywords/cardiac-conduction-disorders","display_name":"cardiac conduction disorders","score":0.7519999742507935},{"id":"https://openalex.org/keywords/atrioventricular-block","display_name":"atrioventricular block","score":0.7699999809265137},{"id":"https://openalex.org/keywords/echocardiographic-abnormalities","display_name":"echocardiographic abnormalities","score":0.6470000147819519},{"id":"https://openalex.org/keywords/asymptomatic-relatives","display_name":"asymptomatic relatives","score":0.5550000071525574},{"id":"https://openalex.org/keywords/johannesburg","display_name":"Johannesburg","score":0.7990000247955322},{"id":"https://openalex.org/keywords/patient-demographics","display_name":"patient demographics","score":0.6480000019073486},{"id":"https://openalex.org/keywords/electrocardiographic-screening","display_name":"electrocardiogram screening","score":0.6869999766349792}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9164459109306335},{"id":"https://openalex.org/C188997412","wikidata":"https://www.wikidata.org/wiki/Q1640386","display_name":"Proband","level":4,"score":0.799035906791687},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.7962517738342285},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.6657346487045288},{"id":"https://openalex.org/C22593422","wikidata":"https://www.wikidata.org/wiki/Q3242583","display_name":"Pedigree chart","level":3,"score":0.6499350070953369},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5348910689353943},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.506777822971344},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4542572498321533},{"id":"https://openalex.org/C2779862289","wikidata":"https://www.wikidata.org/wiki/Q25098571","display_name":"First-degree relatives","level":3,"score":0.44477272033691406},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.43354180455207825},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.41528552770614624},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3266940116882324},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.08857643604278564},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08649870753288269},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005192","descriptor_name":"Family Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013019","descriptor_name":"South Africa","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.7196/samj.2019.v109i9.13936","doi":"https://doi.org/10.7196/samj.2019.v109i9.13936","is_oa":true,"landing_page_url":"https://doi.org/10.7196/samj.2019.v109i9.13936","pdf_url":"http://www.samj.org.za/index.php/samj/article/download/12695/8948","source":{"id":"https://openalex.org/S147026946","display_name":"South African Medical Journal","issn_l":"0256-9574","issn":["0256-9574","2078-5135"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["dhet","doaj","dongbi-c","doyens","jpps-2","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315351","host_organization_name":"Health and Medical Publishing Group","host_organization_lineage":["https://openalex.org/P4310315351"],"host_organization_lineage_names":["Health and Medical Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African Medical Journal","raw_type":"journal-article"},{"id":"pmid:31635593","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31635593","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7196/samj.2019.v109i9.13936","doi":"https://doi.org/10.7196/samj.2019.v109i9.13936","is_oa":true,"landing_page_url":"https://doi.org/10.7196/samj.2019.v109i9.13936","pdf_url":"http://www.samj.org.za/index.php/samj/article/download/12695/8948","source":{"id":"https://openalex.org/S147026946","display_name":"South African Medical Journal","issn_l":"0256-9574","issn":["0256-9574","2078-5135"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["dhet","doaj","dongbi-c","doyens","jpps-2","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310315351","host_organization_name":"Health and Medical Publishing Group","host_organization_lineage":["https://openalex.org/P4310315351"],"host_organization_lineage_names":["Health and Medical Publishing Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2971408331.pdf","grobid_xml":"https://content.openalex.org/works/W2971408331.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W143396582","https://openalex.org/W2023317230","https://openalex.org/W2051152155","https://openalex.org/W2077307965","https://openalex.org/W2097138831","https://openalex.org/W2111321537","https://openalex.org/W2121197940","https://openalex.org/W2129302503","https://openalex.org/W2132248940","https://openalex.org/W2147550085","https://openalex.org/W2157941678","https://openalex.org/W2167259218","https://openalex.org/W2171615081","https://openalex.org/W2179894531","https://openalex.org/W2237393579","https://openalex.org/W2325164739","https://openalex.org/W2549116887","https://openalex.org/W2590445414","https://openalex.org/W2766431870","https://openalex.org/W6884312047"],"related_works":["https://openalex.org/W1973063329","https://openalex.org/W2315633478","https://openalex.org/W166589975","https://openalex.org/W2150739339","https://openalex.org/W2889289500","https://openalex.org/W2019166705","https://openalex.org/W4311737073","https://openalex.org/W1968429813","https://openalex.org/W4306254952","https://openalex.org/W1967421571"],"abstract_inverted_index":{"BACKGROUND:":[0],"Familial":[1],"disease":[2,60,125],"is":[3,30,56],"implicated":[4],"in":[5,24,99,189,284,313],"20":[6],"-":[7,250],"50%":[8],"of":[9,11,19,38,58,68,123,155,187,201,220,233,246,261,267,293,302,338,362],"cases":[10],"idiopathic":[12],"dilated":[13,222],"cardiomyopathy":[14,223],"(IDCM)":[15],"worldwide.":[16],"The":[17,113,182,199],"contribution":[18],"familial":[20,59,124,221,234],"factors":[21],"to":[22,52,117,135,217,357],"IDCM":[23,41,90,188,328,344],"the":[25,35,100,119,136,141,190,268,282,294,300],"Johannesburg":[26,47],"area,":[27],"South":[28],"Africa,":[29],"unknown.":[31],"OBJECTIVES:":[32],"To":[33],"describe":[34],"demographic":[36],"details":[37],"patients":[39,228],"with":[40,89,242,259,274],"who":[42,374],"presented":[43],"at":[44,78,83,185,230,371],"Charlotte":[45],"Maxeke":[46],"Academic":[48],"Hospital":[49],"(CMJAH),":[50],"and":[51,65,91,94,126,162,179,215,225,321,335,360],"determine":[53],"if":[54],"there":[55,145],"evidence":[57],"through":[61],"family":[62,104,137,148,158,238,255,333,341,350,369],"history":[63,138,334],"assessment":[64],"clinical":[66,336],"screening":[67,152,337,356],"relatives.":[69],"METHODS:":[70],"This":[71],"was":[72,106,192],"a":[73,79,171,243,303,331,382],"single-centre,":[74],"cohort":[75],"study":[76],"performed":[77],"quaternary":[80],"care":[81],"centre":[82],"CMJAH.":[84],"Fifty":[85],"unrelated":[86],"probands":[87,191,202],"diagnosed":[88],"available":[92,150],"first-":[93],"second-degree":[95,164,323],"relatives":[96,273,292],"were":[97,115,146,166,203,213,229,240,257],"included":[98,170],"study.":[101],"A":[102],"three-generation":[103,332],"pedigree":[105],"drawn":[107],"up":[108],"for":[109,151,153,327,355],"all":[110,290,339],"50":[111,142,208],"probands.":[112],"pedigrees":[114,209],"analysed":[116],"identify":[118,368],"presence":[120],"or":[121,132,263,297,308],"absence":[122],"categorised":[127],"as":[128],"positive,":[129],"intermediate,":[130],"negative":[131],"unreliable":[133],"according":[134],"obtained.":[139],"From":[140],"proband":[143],"cases,":[144],"21":[147,269],"members":[149,159,239,256,351,370],"features":[154,260],"IDCM.":[156,363],"Eighty-two":[157,236],"(55":[160],"first-degree":[161,291,320,340],"27":[163],"relatives)":[165],"screened":[167,271],"clinically.":[168],"Screening":[169,326],"personal":[172],"history,":[173],"full":[174],"physical":[175],"examination,":[176],"electrocardiogram":[177],"(ECG)":[178],"echocardiogram.":[180],"RESULTS:":[181],"mean":[183],"age":[184,245],"diagnosis":[186],"41.7":[193],"(standard":[194],"deviation":[195],"(SD)":[196],"12.4)":[197],"years.":[198,252],"majority":[200],"males":[204],"(n=38;":[205],"76%).":[206],"Of":[207],"analysed,":[210],"14":[211],"(28%)":[212],"positive":[214],"likely":[216],"be":[218,381],"indicative":[219],"(DCM),":[224],"9":[226,319],"(18%)":[227],"intermediate":[231],"risk":[232],"disease.":[235],"asymptomatic":[237,254],"screened,":[241],"median":[244],"33":[247],"(range":[248],"11":[249],"76)":[251],"No":[253],"identified":[258,278,298],"DCM":[262,277],"presymptomatic":[264,276],"DCM.":[265],"Eleven":[266],"families":[270,286,315],"had":[272],"possible":[275],"by":[279],"abnormalities":[280],"on":[281,299],"echocardiogram":[283],"3":[285],"(14.3%)":[287],"(4":[288],"individuals;":[289,318],"index":[295],"case)":[296],"basis":[301],"conduction":[304],"defect":[305],"(an":[306],"arrhythmia":[307],"first-/":[309],"second-/third-degree":[310],"heart":[311],"block)":[312],"8":[314],"(72.7%)":[316],"(11":[317],"2":[322],"relatives).":[324],"CONCLUSIONS:":[325],"should":[329,352],"include":[330],"members.":[342],"As":[343],"has":[345],"an":[346],"age-related":[347],"penetrance,":[348],"at-risk":[349],"receive":[353],"follow-up":[354],"assess":[358],"symptoms":[359],"signs":[361],"Genetic":[364],"testing":[365],"would":[366,375],"potentially":[367],"high":[372],"risk,":[373],"benefit":[376],"from":[377],"screening;":[378],"this":[379],"might":[380],"less":[383],"expensive":[384],"option.":[385]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-09-12T00:00:00"}