{"id":"https://openalex.org/W29709618","doi":null,"title":"Interactions of natural health products with biomedical cancer treatments.","display_name":"Interactions of natural health products with biomedical cancer treatments.","publication_year":2008,"publication_date":"2008-08-01","ids":{"openalex":"https://openalex.org/W29709618","mag":"29709618","pmid":"https://pubmed.ncbi.nlm.nih.gov/18769615","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2528552"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2528552","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Oncol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057397030","display_name":"Dugald Seely","orcid":"https://orcid.org/0000-0003-4893-5254","observed_orcids":["https://orcid.org/0000-0003-4893-5254"]},"institutions":[{"id":"https://openalex.org/I149634359","display_name":"Canadian College of Naturopathic Medicine","ror":"https://ror.org/03pjwtr87","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I149634359"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D Seely","raw_affiliation_strings":["Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto,ON. dseely@ccnm.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Clinical Epidemiology, The Canadian College of Naturopathic Medicine, Toronto,ON. dseely@ccnm.edu","institution_ids":["https://openalex.org/I149634359"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079992058","display_name":"Doreen Oneschuk","orcid":"https://orcid.org/0000-0001-8976-4610","observed_orcids":["https://orcid.org/0000-0001-8976-4610"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Oneschuk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.6607,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.93294096,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"15 Suppl 2","issue":null,"first_page":"s109.es81","last_page":"s10.es6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13444","display_name":"Traditional Chinese Medicine Clinical Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-health-products","display_name":"natural health products","score":1.0},{"id":"https://openalex.org/keywords/alternative-medicine","display_name":"complementary and alternative medicine","score":0.9940000176429749},{"id":"https://openalex.org/keywords/cancer-patients","display_name":"cancer patients","score":0.7940000295639038},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.8140000104904175},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.9449999928474426},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticancer-effects","display_name":"anticancer effects","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7931210994720459},{"id":"https://openalex.org/C2777363581","wikidata":"https://www.wikidata.org/wiki/Q15098235","display_name":"Harm","level":2,"score":0.6641002893447876},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6382330060005188},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.592193603515625},{"id":"https://openalex.org/C2776916960","wikidata":"https://www.wikidata.org/wiki/Q637156","display_name":"Warrant","level":2,"score":0.5635688900947571},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5553723573684692},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.4447324573993683},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15320932865142822},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12356984615325928},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.09945270419120789},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0885331928730011},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C106159729","wikidata":"https://www.wikidata.org/wiki/Q2294553","display_name":"Financial economics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2528552","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Oncol","raw_type":"Text"},{"id":"pmid:18769615","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18769615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current oncology (Toronto, Ont.)","raw_type":"Journal Article"},{"id":"mag:29709618","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18769615","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2528552","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2528552/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Curr Oncol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W29709618.pdf","grobid_xml":"https://content.openalex.org/works/W29709618.grobid-xml"},"referenced_works_count":113,"referenced_works":["https://openalex.org/W117457101","https://openalex.org/W122099627","https://openalex.org/W1514504985","https://openalex.org/W1534042983","https://openalex.org/W1967234838","https://openalex.org/W1968967017","https://openalex.org/W1970624988","https://openalex.org/W1970690033","https://openalex.org/W1970963818","https://openalex.org/W1971308124","https://openalex.org/W1974177203","https://openalex.org/W1976301396","https://openalex.org/W1978924740","https://openalex.org/W1980292972","https://openalex.org/W1982751346","https://openalex.org/W1983660130","https://openalex.org/W1985065867","https://openalex.org/W1985579798","https://openalex.org/W1988301104","https://openalex.org/W1993805292","https://openalex.org/W1994057795","https://openalex.org/W1995167508","https://openalex.org/W1998825194","https://openalex.org/W1999202014","https://openalex.org/W2000024765","https://openalex.org/W2003245098","https://openalex.org/W2003490109","https://openalex.org/W2009185888","https://openalex.org/W2012484330","https://openalex.org/W2015655959","https://openalex.org/W2015711926","https://openalex.org/W2017099176","https://openalex.org/W2018300894","https://openalex.org/W2018535477","https://openalex.org/W2018955711","https://openalex.org/W2022688266","https://openalex.org/W2024308239","https://openalex.org/W2024648720","https://openalex.org/W2038262824","https://openalex.org/W2039378021","https://openalex.org/W2039395036","https://openalex.org/W2039406936","https://openalex.org/W2041136085","https://openalex.org/W2041512459","https://openalex.org/W2043303178","https://openalex.org/W2045404756","https://openalex.org/W2046138018","https://openalex.org/W2053754605","https://openalex.org/W2057013967","https://openalex.org/W2059624486","https://openalex.org/W2060004662","https://openalex.org/W2060803082","https://openalex.org/W2062062765","https://openalex.org/W2062166266","https://openalex.org/W2062343573","https://openalex.org/W2064183272","https://openalex.org/W2064501521","https://openalex.org/W2066021473","https://openalex.org/W2067252902","https://openalex.org/W2069303416","https://openalex.org/W2074839099","https://openalex.org/W2085104178","https://openalex.org/W2085614949","https://openalex.org/W2090206349","https://openalex.org/W2090251305","https://openalex.org/W2095950966","https://openalex.org/W2101090426","https://openalex.org/W2102045361","https://openalex.org/W2102475188","https://openalex.org/W2102664366","https://openalex.org/W2104199154","https://openalex.org/W2105500446","https://openalex.org/W2111626122","https://openalex.org/W2116749308","https://openalex.org/W2118031614","https://openalex.org/W2118979497","https://openalex.org/W2120804125","https://openalex.org/W2121660666","https://openalex.org/W2124800758","https://openalex.org/W2126152724","https://openalex.org/W2128582971","https://openalex.org/W2131338584","https://openalex.org/W2132001873","https://openalex.org/W2132804094","https://openalex.org/W2133079030","https://openalex.org/W2133777904","https://openalex.org/W2137048483","https://openalex.org/W2138020718","https://openalex.org/W2144299645","https://openalex.org/W2148329528","https://openalex.org/W2148484573","https://openalex.org/W2148587874","https://openalex.org/W2148628698","https://openalex.org/W2152948824","https://openalex.org/W2154922703","https://openalex.org/W2158251611","https://openalex.org/W2168807041","https://openalex.org/W2171687298","https://openalex.org/W2179375682","https://openalex.org/W2220874307","https://openalex.org/W2278302766","https://openalex.org/W2295555304","https://openalex.org/W2400983324","https://openalex.org/W2411166080","https://openalex.org/W2467022164","https://openalex.org/W2517508667","https://openalex.org/W2548543256","https://openalex.org/W2554132869","https://openalex.org/W2738891826","https://openalex.org/W2740458460","https://openalex.org/W2781957004","https://openalex.org/W2810993483","https://openalex.org/W6746468913"],"related_works":["https://openalex.org/W7098948455","https://openalex.org/W4233281177","https://openalex.org/W1980292972","https://openalex.org/W4415657707","https://openalex.org/W2105831683","https://openalex.org/W4318257861","https://openalex.org/W4307373108","https://openalex.org/W3099797308","https://openalex.org/W2922652085","https://openalex.org/W4411931125"],"abstract_inverted_index":{"The":[0],"use":[1],"of":[2,11,49,63,88,95,120,133,138],"complementary":[3],"and":[4,25,46,66,112],"alternative":[5],"medicine":[6],"(CAM),":[7],"including":[8],"the":[9,29,60,77,86,131],"ingestion":[10],"natural":[12],"health":[13],"products":[14,55],"(NHPS),":[15],"is":[16,28,81,127,161],"common":[17],"among":[18],"cancer":[19],"patients.":[20],"Of":[21],"concern":[22],"to":[23,58,84,110,113],"clinicians":[24],"patients":[26],"alike":[27],"possibility":[30],"that":[31,42,52,76,98],"cam,":[32],"used":[33],"concurrently":[34],"with":[35,41],"biomedical":[36],"therapy,":[37,43],"may":[38,99,145],"interact":[39],"poorly":[40],"especially":[44],"chemotherapy":[45,111],"radiotherapy.":[47],"Proponents":[48],"NHPS":[50,97,139],"argue":[51],"taking":[53],"such":[54],"can":[56,67],"help":[57],"reduce":[59],"side":[61],"effects":[62],"conventional":[64,143],"therapy":[65,144],"provide":[68,100],"an":[69],"additional":[70],"anticancer":[71],"effect.":[72],"However,":[73],"opponents":[74],"insist":[75],"potential":[78],"for":[79],"harm":[80],"too":[82],"great":[83],"warrant":[85],"risk":[87],"concurrent":[89,149],"administration.":[90],"There":[91],"are":[92],"promising":[93],"examples":[94],"specific":[96,164],"patient":[101],"benefit":[102],"even":[103],"when":[104,129],"given":[105],"in":[106,117],"close":[107],"proximity":[108],"both":[109],"radiotherapy,":[114],"but":[115],"unfortunately,":[116],"part":[118],"because":[119],"a":[121,155],"rather":[122],"limited":[123],"evidence":[124,160],"base,":[125],"caution":[126],"warranted":[128],"considering":[130],"issue":[132],"therapeutic":[134],"interactions.":[135,165],"Strategic":[136],"application":[137,150],"before":[140],"or":[141],"after":[142],"be":[146,152],"considered;":[147],"however,":[148],"should":[151],"avoided":[153],"as":[154],"general":[156],"principle":[157],"until":[158],"further":[159],"available":[162],"regarding":[163]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}
