{"id":"https://openalex.org/W2970256155","doi":"https://doi.org/10.1016/j.ppedcard.2019.101145","title":"Genomics and precision medicine to direct statin use in the young","display_name":"Genomics and precision medicine to direct statin use in the young","publication_year":2019,"publication_date":"2019-08-27","ids":{"openalex":"https://openalex.org/W2970256155","doi":"https://doi.org/10.1016/j.ppedcard.2019.101145","mag":"2970256155","pmid":"https://pubmed.ncbi.nlm.nih.gov/32855589","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7448579"},"language":"en","primary_location":{"id":"doi:10.1016/j.ppedcard.2019.101145","doi":"https://doi.org/10.1016/j.ppedcard.2019.101145","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ppedcard.2019.101145","pdf_url":null,"source":{"id":"https://openalex.org/S187747600","display_name":"Progress in Pediatric Cardiology","issn_l":"1058-9813","issn":["1058-9813","1558-1519"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Pediatric Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7448579","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063675300","display_name":"Jonathan B. Wagner","orcid":"https://orcid.org/0000-0001-7690-6798","observed_orcids":["https://orcid.org/0000-0001-7690-6798"]},"institutions":[{"id":"https://openalex.org/I1328594524","display_name":"Children's Mercy Hospital","ror":"https://ror.org/04zfmcq84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328594524"]},{"id":"https://openalex.org/I75421653","display_name":"University of Missouri\u2013Kansas City","ror":"https://ror.org/01w0d5g70","country_code":"US","type":"education","lineage":["https://openalex.org/I75421653"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jonathan B. Wagner","raw_affiliation_strings":["Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO","Division of Clinical Pharmacology, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO","Ward Family Heart Center, Kansas City, MO","Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, United States of America","Division of Clinical Pharmacology, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO, United States of America","Ward Family Heart Center, Kansas City, MO, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO","institution_ids":["https://openalex.org/I75421653"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO","institution_ids":["https://openalex.org/I1328594524"]},{"raw_affiliation_string":"Ward Family Heart Center, Kansas City, MO","institution_ids":[]},{"raw_affiliation_string":"Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, MO, United States of America","institution_ids":["https://openalex.org/I75421653"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Medical Toxicology and Therapeutic Innovation, Children's Mercy, Kansas City, MO, United States of America","institution_ids":["https://openalex.org/I1328594524"]},{"raw_affiliation_string":"Ward Family Heart Center, Kansas City, MO, United States of America","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5063675300"],"corresponding_institution_ids":["https://openalex.org/I1328594524","https://openalex.org/I75421653"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":null,"fwci":0.4911,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65005326,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"54","issue":null,"first_page":"101145","last_page":"101145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9092000126838684,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.04650000110268593,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.8270000219345093},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"precision medicine","score":0.8349999785423279},{"id":"https://openalex.org/keywords/pediatric-cardiology","display_name":"pediatric cardiology","score":0.9679999947547913},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.7839999794960022},{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.7599999904632568},{"id":"https://openalex.org/keywords/drug-disposition","display_name":"drug disposition","score":0.8960000276565552}],"concepts":[{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.8398581743240356},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8061601519584656},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.5656431913375854},{"id":"https://openalex.org/C2992545694","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Genomic medicine","level":2,"score":0.4466700851917267},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.4267405569553375},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.4190846085548401},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3333345055580139},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.32952868938446045},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3232434391975403},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.30336207151412964},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.2994243800640106},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2437291145324707},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2001858949661255},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.15459099411964417},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08836674690246582},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07525858283042908},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ppedcard.2019.101145","doi":"https://doi.org/10.1016/j.ppedcard.2019.101145","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ppedcard.2019.101145","pdf_url":null,"source":{"id":"https://openalex.org/S187747600","display_name":"Progress in Pediatric Cardiology","issn_l":"1058-9813","issn":["1058-9813","1558-1519"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Pediatric Cardiology","raw_type":"journal-article"},{"id":"pmid:32855589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32855589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in pediatric cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7448579","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7448579","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Prog Pediatr Cardiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7448579","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7448579","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Prog Pediatr Cardiol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G315238555","display_name":null,"funder_award_id":"KL2TR002367","funder_id":"https://openalex.org/F4320310131","funder_display_name":"University of Kansas"},{"id":"https://openalex.org/G6700595336","display_name":null,"funder_award_id":"13CRP17110023","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G9000895681","display_name":"Institutional Career Development Core","funder_award_id":"KL2TR002367","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320310131","display_name":"University of Kansas","ror":"https://ror.org/001tmjg57"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W106575814","https://openalex.org/W1657886501","https://openalex.org/W1884274622","https://openalex.org/W1934405147","https://openalex.org/W1970750464","https://openalex.org/W1974187375","https://openalex.org/W1975887871","https://openalex.org/W1978006382","https://openalex.org/W1994748439","https://openalex.org/W1994834284","https://openalex.org/W2002886895","https://openalex.org/W2007238584","https://openalex.org/W2010033213","https://openalex.org/W2016918159","https://openalex.org/W2017283757","https://openalex.org/W2018645250","https://openalex.org/W2019329200","https://openalex.org/W2021173802","https://openalex.org/W2034686245","https://openalex.org/W2039141364","https://openalex.org/W2039986849","https://openalex.org/W2048086967","https://openalex.org/W2052925329","https://openalex.org/W2057250118","https://openalex.org/W2060427373","https://openalex.org/W2084604930","https://openalex.org/W2085439023","https://openalex.org/W2089205302","https://openalex.org/W2103037352","https://openalex.org/W2106658801","https://openalex.org/W2110231085","https://openalex.org/W2110921888","https://openalex.org/W2113719939","https://openalex.org/W2133448117","https://openalex.org/W2152218609","https://openalex.org/W2153681048","https://openalex.org/W2156173568","https://openalex.org/W2161453510","https://openalex.org/W2189823828","https://openalex.org/W2262354148","https://openalex.org/W2280638736","https://openalex.org/W2318944362","https://openalex.org/W2336250349","https://openalex.org/W2342226006","https://openalex.org/W2444137400","https://openalex.org/W2556104363","https://openalex.org/W2739873817","https://openalex.org/W2790963960","https://openalex.org/W2902190679","https://openalex.org/W2905106264","https://openalex.org/W2913705661","https://openalex.org/W2949506289","https://openalex.org/W4205396676","https://openalex.org/W4249964811","https://openalex.org/W6695474964"],"related_works":["https://openalex.org/W106575814","https://openalex.org/W2736571152","https://openalex.org/W7213928242","https://openalex.org/W2804727148","https://openalex.org/W3174897907","https://openalex.org/W2083924223","https://openalex.org/W2103037352","https://openalex.org/W4256459876","https://openalex.org/W2220678796","https://openalex.org/W2087462834"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-09-05T00:00:00"}