{"id":"https://openalex.org/W2970103499","doi":"https://doi.org/10.1128/cmr.00031-19","title":"Epidemiology and Treatment of Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa Infections","display_name":"Epidemiology and Treatment of Multidrug-Resistant and Extensively Drug-Resistant Pseudomonas aeruginosa Infections","publication_year":2019,"publication_date":"2019-08-27","ids":{"openalex":"https://openalex.org/W2970103499","doi":"https://doi.org/10.1128/cmr.00031-19","mag":"2970103499","pmid":"https://pubmed.ncbi.nlm.nih.gov/31462403"},"language":"en","primary_location":{"id":"doi:10.1128/cmr.00031-19","doi":"https://doi.org/10.1128/cmr.00031-19","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cmr.00031-19","pdf_url":"https://cmr.asm.org/content/cmr/32/4/e00031-19.full.pdf","source":{"id":"https://openalex.org/S112662651","display_name":"Clinical Microbiology Reviews","issn_l":"0893-8512","issn":["0893-8512","1070-6305","1098-6618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology Reviews","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://cmr.asm.org/content/cmr/32/4/e00031-19.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025716337","display_name":"Juan Pablo Horcajada","orcid":"https://orcid.org/0000-0001-9873-5459","observed_orcids":["https://orcid.org/0000-0001-9873-5459"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I4210120947","display_name":"Red Espanola de Investigacion en Patologia Infecciosa","ror":"https://ror.org/02nwht553","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210120947"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan P. Horcajada","raw_affiliation_strings":["Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain"],"raw_orcid":"https://orcid.org/0000-0001-9873-5459","affiliations":[{"raw_affiliation_string":"Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942","https://openalex.org/I4210130874","https://openalex.org/I4210156109"]},{"raw_affiliation_string":"Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain","institution_ids":["https://openalex.org/I4210120947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081965144","display_name":"M. Montero","orcid":"https://orcid.org/0000-0001-5991-6804","observed_orcids":["https://orcid.org/0000-0001-5991-6804"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I4210120947","display_name":"Red Espanola de Investigacion en Patologia Infecciosa","ror":"https://ror.org/02nwht553","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210120947"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Milagro Montero","raw_affiliation_strings":["Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain"],"raw_orcid":"https://orcid.org/0000-0001-5991-6804","affiliations":[{"raw_affiliation_string":"Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942","https://openalex.org/I4210130874","https://openalex.org/I4210156109"]},{"raw_affiliation_string":"Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain","institution_ids":["https://openalex.org/I4210120947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048017496","display_name":"Antonio Oliver","orcid":"https://orcid.org/0000-0001-9327-1894","observed_orcids":["https://orcid.org/0000-0001-9327-1894"]},"institutions":[{"id":"https://openalex.org/I4210126021","display_name":"Health Research Institute of the Balearic Islands","ror":"https://ror.org/037xbgq12","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210126021"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Antonio Oliver","raw_affiliation_strings":["Service of Microbiology, Hospital Son Espases, Instituto de Investigaci\u00f3n Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain"],"raw_orcid":"https://orcid.org/0000-0001-9327-1894","affiliations":[{"raw_affiliation_string":"Service of Microbiology, Hospital Son Espases, Instituto de Investigaci\u00f3n Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain","institution_ids":["https://openalex.org/I4210126021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064384865","display_name":"Luisa Sorl\u00ed","orcid":"https://orcid.org/0000-0001-9562-514X","observed_orcids":["https://orcid.org/0000-0001-9562-514X"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210120947","display_name":"Red Espanola de Investigacion en Patologia Infecciosa","ror":"https://ror.org/02nwht553","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210120947"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Luisa Sorl\u00ed","raw_affiliation_strings":["Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Pompeu Fabra, Barcelona, Spain","Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Pompeu Fabra, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210130874","https://openalex.org/I4210156109"]},{"raw_affiliation_string":"Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain","institution_ids":["https://openalex.org/I4210120947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033921563","display_name":"S\u00f2nia Luque","orcid":"https://orcid.org/0000-0002-3215-320X","observed_orcids":["https://orcid.org/0000-0002-3215-320X"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210136145","display_name":"Municipal Institute for Medical Research","ror":"https://ror.org/039evc422","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210136145"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"S\u00f2nia Luque","raw_affiliation_strings":["Service of Pharmacy, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service of Pharmacy, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942","https://openalex.org/I4210130874","https://openalex.org/I4210136145","https://openalex.org/I4210156109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018232762","display_name":"S\u00edlvia G\u00f3mez-Zorrilla","orcid":"https://orcid.org/0000-0002-5987-068X","observed_orcids":["https://orcid.org/0000-0002-5987-068X"]},"institutions":[{"id":"https://openalex.org/I170486558","display_name":"Universitat Pompeu Fabra","ror":"https://ror.org/04n0g0b29","country_code":"ES","type":"education","lineage":["https://openalex.org/I170486558"]},{"id":"https://openalex.org/I4210120947","display_name":"Red Espanola de Investigacion en Patologia Infecciosa","ror":"https://ror.org/02nwht553","country_code":"ES","type":"other","lineage":["https://openalex.org/I4210120947"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Silvia G\u00f3mez-Zorrilla","raw_affiliation_strings":["Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Pompeu Fabra, Barcelona, Spain","Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service of Infectious Diseases, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Pompeu Fabra, Barcelona, Spain","institution_ids":["https://openalex.org/I170486558","https://openalex.org/I4210130874","https://openalex.org/I4210156109"]},{"raw_affiliation_string":"Spanish Network for Research in Infectious Diseases (REIPI), Madrid, Spain","institution_ids":["https://openalex.org/I4210120947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056852015","display_name":"Natividad Benito","orcid":"https://orcid.org/0000-0001-6410-013X","observed_orcids":["https://orcid.org/0000-0001-6410-013X"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I2801795740","display_name":"Hospital de Sant Pau","ror":"https://ror.org/059n1d175","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2801795740"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Natividad Benito","raw_affiliation_strings":["Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Institut d'Investigaci\u00f3 Biom\u00e8dica Sant Pau, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"],"raw_orcid":"https://orcid.org/0000-0001-6410-013X","affiliations":[{"raw_affiliation_string":"Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Institut d'Investigaci\u00f3 Biom\u00e8dica Sant Pau, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942","https://openalex.org/I2801795740"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027284548","display_name":"Santiago Grau","orcid":"https://orcid.org/0000-0002-8428-1836","observed_orcids":["https://orcid.org/0000-0002-8428-1836"]},"institutions":[{"id":"https://openalex.org/I123044942","display_name":"Universitat Aut\u00f2noma de Barcelona","ror":"https://ror.org/052g8jq94","country_code":"ES","type":"education","lineage":["https://openalex.org/I123044942"]},{"id":"https://openalex.org/I4210130874","display_name":"Hospital Del Mar","ror":"https://ror.org/03a8gac78","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130874"]},{"id":"https://openalex.org/I4210136145","display_name":"Municipal Institute for Medical Research","ror":"https://ror.org/039evc422","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210136145"]},{"id":"https://openalex.org/I4210156109","display_name":"Hospital del Mar Research Institute","ror":"https://ror.org/042nkmz09","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210156109","https://openalex.org/I4387153040"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Santiago Grau","raw_affiliation_strings":["Service of Pharmacy, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service of Pharmacy, Hospital del Mar, Infectious Pathology and Antimicrobials Research Group, Institut Hospital del Mar d\u2019Investigacions M\u00e8diques (IMIM), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I123044942","https://openalex.org/I4210130874","https://openalex.org/I4210136145","https://openalex.org/I4210156109"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":25.8517,"has_fulltext":false,"cited_by_count":965,"citation_normalized_percentile":{"value":0.99883544,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"32","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.04129999876022339,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9789999723434448},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.9729999899864197},{"id":"https://openalex.org/keywords/extensively-drug-resistant-bacteria","display_name":"extensively drug-resistant bacteria","score":0.9089999794960022},{"id":"https://openalex.org/keywords/antibiotic-resistance-mechanisms","display_name":"antibiotic resistance mechanisms","score":0.7310000061988831},{"id":"https://openalex.org/keywords/imipenem-relebactam","display_name":"imipenem-relebactam","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cefepime-zidebactam","display_name":"cefepime/zidebactam","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cefiderocol","display_name":"cefiderocol","score":0.9990000128746033},{"id":"https://openalex.org/keywords/new-antibiotics","display_name":"novel antibiotics","score":0.47600001096725464},{"id":"https://openalex.org/keywords/vaccines","display_name":"vaccines","score":0.5979999899864197},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8679999709129333},{"id":"https://openalex.org/keywords/bacteriocins","display_name":"bacteriocins","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-quorum-sensing","display_name":"anti-quorum sensing","score":0.9490000009536743},{"id":"https://openalex.org/keywords/bacteriophages","display_name":"bacteriophages","score":0.8930000066757202}],"concepts":[{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.8165055513381958},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6792933940887451},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.6273826360702515},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.6152786016464233},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5119853615760803},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.49255046248435974},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4187208414077759},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.39136096835136414},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3754749894142151},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37283855676651},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1541050374507904},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.1352725625038147},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.09362268447875977},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.054915398359298706}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011550","descriptor_name":"Pseudomonas aeruginosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011552","descriptor_name":"Pseudomonas Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/cmr.00031-19","doi":"https://doi.org/10.1128/cmr.00031-19","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cmr.00031-19","pdf_url":"https://cmr.asm.org/content/cmr/32/4/e00031-19.full.pdf","source":{"id":"https://openalex.org/S112662651","display_name":"Clinical Microbiology Reviews","issn_l":"0893-8512","issn":["0893-8512","1070-6305","1098-6618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology Reviews","raw_type":"journal-article"},{"id":"pmid:31462403","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31462403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical microbiology reviews","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6730496","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6730496","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clin Microbiol Rev","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1128/cmr.00031-19","doi":"https://doi.org/10.1128/cmr.00031-19","is_oa":true,"landing_page_url":"https://doi.org/10.1128/cmr.00031-19","pdf_url":"https://cmr.asm.org/content/cmr/32/4/e00031-19.full.pdf","source":{"id":"https://openalex.org/S112662651","display_name":"Clinical Microbiology Reviews","issn_l":"0893-8512","issn":["0893-8512","1070-6305","1098-6618"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-3","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology Reviews","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8500000238418579,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2970103499.pdf"},"referenced_works_count":365,"referenced_works":["https://openalex.org/W204406804","https://openalex.org/W1481920844","https://openalex.org/W1548036406","https://openalex.org/W1557300516","https://openalex.org/W1582342805","https://openalex.org/W1588092333","https://openalex.org/W1776825207","https://openalex.org/W1793924104","https://openalex.org/W1800273246","https://openalex.org/W1804516907","https://openalex.org/W1904922831","https://openalex.org/W1932296131","https://openalex.org/W1937852950","https://openalex.org/W1948640124","https://openalex.org/W1959513603","https://openalex.org/W1963802535","https://openalex.org/W1964226118","https://openalex.org/W1964492077","https://openalex.org/W1965061186","https://openalex.org/W1966390128","https://openalex.org/W1971489011","https://openalex.org/W1977482442","https://openalex.org/W1978057383","https://openalex.org/W1978839325","https://openalex.org/W1979976798","https://openalex.org/W1980325515","https://openalex.org/W1982091703","https://openalex.org/W1982349279","https://openalex.org/W1983774126","https://openalex.org/W1984693521","https://openalex.org/W1984907372","https://openalex.org/W1986795560","https://openalex.org/W1988629557","https://openalex.org/W1993956372","https://openalex.org/W1994909653","https://openalex.org/W1995689455","https://openalex.org/W1996587466","https://openalex.org/W1999979510","https://openalex.org/W2001654877","https://openalex.org/W2002773042","https://openalex.org/W2002834465","https://openalex.org/W2003961381","https://openalex.org/W2004918900","https://openalex.org/W2005031995","https://openalex.org/W2005824807","https://openalex.org/W2006533357","https://openalex.org/W2008679353","https://openalex.org/W2011253627","https://openalex.org/W2012372004","https://openalex.org/W2013974039","https://openalex.org/W2015190955","https://openalex.org/W2015720649","https://openalex.org/W2015984063","https://openalex.org/W2019288208","https://openalex.org/W2021909817","https://openalex.org/W2023328426","https://openalex.org/W2026335574","https://openalex.org/W2026698060","https://openalex.org/W2027225993","https://openalex.org/W2031593458","https://openalex.org/W2033235589","https://openalex.org/W2037685605","https://openalex.org/W2043179794","https://openalex.org/W2043209435","https://openalex.org/W2045211463","https://openalex.org/W2046290563","https://openalex.org/W2049229095","https://openalex.org/W2052459767","https://openalex.org/W2052899239","https://openalex.org/W2055399323","https://openalex.org/W2056847691","https://openalex.org/W2057418340","https://openalex.org/W2062238065","https://openalex.org/W2065791238","https://openalex.org/W2069107501","https://openalex.org/W2070752040","https://openalex.org/W2070828665","https://openalex.org/W2072066156","https://openalex.org/W2073556554","https://openalex.org/W2075287054","https://openalex.org/W2078064161","https://openalex.org/W2079925139","https://openalex.org/W2081528817","https://openalex.org/W2081697175","https://openalex.org/W2086919865","https://openalex.org/W2087993538","https://openalex.org/W2090570219","https://openalex.org/W2091090665","https://openalex.org/W2096148345","https://openalex.org/W2096606588","https://openalex.org/W2097145546","https://openalex.org/W2097533517","https://openalex.org/W2098310975","https://openalex.org/W2099264750","https://openalex.org/W2100030863","https://openalex.org/W2100773669","https://openalex.org/W2100841241","https://openalex.org/W2102388088","https://openalex.org/W2102732904","https://openalex.org/W2102778949","https://openalex.org/W2103382313","https://openalex.org/W2103752133","https://openalex.org/W2107050135","https://openalex.org/W2107932853","https://openalex.org/W2108378498","https://openalex.org/W2109362895","https://openalex.org/W2110880963","https://openalex.org/W2112209788","https://openalex.org/W2113480160","https://openalex.org/W2113717321","https://openalex.org/W2114545903","https://openalex.org/W2115402841","https://openalex.org/W2116245384","https://openalex.org/W2116950515","https://openalex.org/W2118734761","https://openalex.org/W2119078694","https://openalex.org/W2119209016","https://openalex.org/W2119561074","https://openalex.org/W2119644572","https://openalex.org/W2120266293","https://openalex.org/W2120587721","https://openalex.org/W2120696678","https://openalex.org/W2121636760","https://openalex.org/W2123122657","https://openalex.org/W2123135656","https://openalex.org/W2123978275","https://openalex.org/W2125197050","https://openalex.org/W2125826936","https://openalex.org/W2126058908","https://openalex.org/W2127128579","https://openalex.org/W2127422236","https://openalex.org/W2128136074","https://openalex.org/W2129842338","https://openalex.org/W2130070772","https://openalex.org/W2130730733","https://openalex.org/W2130765730","https://openalex.org/W2131610691","https://openalex.org/W2132086274","https://openalex.org/W2132109557","https://openalex.org/W2132490807","https://openalex.org/W2133740160","https://openalex.org/W2134053082","https://openalex.org/W2134744238","https://openalex.org/W2134896944","https://openalex.org/W2135522266","https://openalex.org/W2137729811","https://openalex.org/W2137799330","https://openalex.org/W2140024196","https://openalex.org/W2140127459","https://openalex.org/W2141060269","https://openalex.org/W2142343447","https://openalex.org/W2143982063","https://openalex.org/W2145037862","https://openalex.org/W2146291304","https://openalex.org/W2148753657","https://openalex.org/W2148795002","https://openalex.org/W2149033372","https://openalex.org/W2149088130","https://openalex.org/W2149623513","https://openalex.org/W2150502003","https://openalex.org/W2150729119","https://openalex.org/W2151685719","https://openalex.org/W2153679512","https://openalex.org/W2153977073","https://openalex.org/W2154015301","https://openalex.org/W2154126135","https://openalex.org/W2155985488","https://openalex.org/W2158518385","https://openalex.org/W2158958674","https://openalex.org/W2159810437","https://openalex.org/W2161460874","https://openalex.org/W2163881342","https://openalex.org/W2164032940","https://openalex.org/W2165923378","https://openalex.org/W2167117360","https://openalex.org/W2167331013","https://openalex.org/W2168223549","https://openalex.org/W2168502103","https://openalex.org/W2168808631","https://openalex.org/W2169951238","https://openalex.org/W2170187421","https://openalex.org/W2170997653","https://openalex.org/W2171444448","https://openalex.org/W2171632431","https://openalex.org/W2176363076","https://openalex.org/W2195031027","https://openalex.org/W2199091941","https://openalex.org/W2203490562","https://openalex.org/W2220788206","https://openalex.org/W2232017074","https://openalex.org/W2262202809","https://openalex.org/W2281337223","https://openalex.org/W2294927917","https://openalex.org/W2301543346","https://openalex.org/W2308304054","https://openalex.org/W2310063671","https://openalex.org/W2310497493","https://openalex.org/W2329413502","https://openalex.org/W2331058291","https://openalex.org/W2339819000","https://openalex.org/W2340133943","https://openalex.org/W2345096571","https://openalex.org/W2345171513","https://openalex.org/W2346226798","https://openalex.org/W2346730904","https://openalex.org/W2407151623","https://openalex.org/W2408072278","https://openalex.org/W2418930205","https://openalex.org/W2419509696","https://openalex.org/W2440036468","https://openalex.org/W2463855494","https://openalex.org/W2470176545","https://openalex.org/W2473016454","https://openalex.org/W2473630156","https://openalex.org/W2489857405","https://openalex.org/W2497449406","https://openalex.org/W2505961383","https://openalex.org/W2507780315","https://openalex.org/W2508377408","https://openalex.org/W2511941815","https://openalex.org/W2519911390","https://openalex.org/W2527705259","https://openalex.org/W2528087434","https://openalex.org/W2528590647","https://openalex.org/W2531311911","https://openalex.org/W2538195174","https://openalex.org/W2538899501","https://openalex.org/W2545469315","https://openalex.org/W2551981896","https://openalex.org/W2555442806","https://openalex.org/W2557470621","https://openalex.org/W2557895104","https://openalex.org/W2566076583","https://openalex.org/W2566638444","https://openalex.org/W2567139420","https://openalex.org/W2568826445","https://openalex.org/W2569599529","https://openalex.org/W2575028928","https://openalex.org/W2577499121","https://openalex.org/W2584184235","https://openalex.org/W2586033112","https://openalex.org/W2586169463","https://openalex.org/W2588163058","https://openalex.org/W2591044857","https://openalex.org/W2592326115","https://openalex.org/W2593444269","https://openalex.org/W2597381021","https://openalex.org/W2597609238","https://openalex.org/W2597657952","https://openalex.org/W2598898392","https://openalex.org/W2601144035","https://openalex.org/W2605200150","https://openalex.org/W2606412122","https://openalex.org/W2614060724","https://openalex.org/W2617124917","https://openalex.org/W2619049102","https://openalex.org/W2620266053","https://openalex.org/W2620438757","https://openalex.org/W2635337892","https://openalex.org/W2683726696","https://openalex.org/W2731060259","https://openalex.org/W2732025234","https://openalex.org/W2736277296","https://openalex.org/W2736611040","https://openalex.org/W2736633473","https://openalex.org/W2737419044","https://openalex.org/W2739079221","https://openalex.org/W2745939174","https://openalex.org/W2746635144","https://openalex.org/W2748897372","https://openalex.org/W2751894072","https://openalex.org/W2751939257","https://openalex.org/W2754981836","https://openalex.org/W2755559441","https://openalex.org/W2756266760","https://openalex.org/W2758091881","https://openalex.org/W2761417493","https://openalex.org/W2761927392","https://openalex.org/W2762251864","https://openalex.org/W2763408425","https://openalex.org/W2764206951","https://openalex.org/W2765377794","https://openalex.org/W2766112856","https://openalex.org/W2769066464","https://openalex.org/W2769523151","https://openalex.org/W2769609314","https://openalex.org/W2769664028","https://openalex.org/W2770431582","https://openalex.org/W2771891407","https://openalex.org/W2773548512","https://openalex.org/W2773882131","https://openalex.org/W2775867344","https://openalex.org/W2777692148","https://openalex.org/W2779019546","https://openalex.org/W2781181029","https://openalex.org/W2783669395","https://openalex.org/W2785470379","https://openalex.org/W2786314763","https://openalex.org/W2788197198","https://openalex.org/W2789749219","https://openalex.org/W2790069031","https://openalex.org/W2790352179","https://openalex.org/W2790955358","https://openalex.org/W2790969462","https://openalex.org/W2791125312","https://openalex.org/W2791383582","https://openalex.org/W2791481114","https://openalex.org/W2791976824","https://openalex.org/W2792462191","https://openalex.org/W2792875856","https://openalex.org/W2793130594","https://openalex.org/W2793753655","https://openalex.org/W2794923017","https://openalex.org/W2794932613","https://openalex.org/W2795056352","https://openalex.org/W2795345046","https://openalex.org/W2795519233","https://openalex.org/W2795869226","https://openalex.org/W2795878486","https://openalex.org/W2796052358","https://openalex.org/W2800004776","https://openalex.org/W2802899356","https://openalex.org/W2803451096","https://openalex.org/W2803919049","https://openalex.org/W2804230504","https://openalex.org/W2804303558","https://openalex.org/W2804498042","https://openalex.org/W2807903540","https://openalex.org/W2808163815","https://openalex.org/W2809078834","https://openalex.org/W2809662916","https://openalex.org/W2810112672","https://openalex.org/W2822687727","https://openalex.org/W2883244120","https://openalex.org/W2883285900","https://openalex.org/W2883881590","https://openalex.org/W2884175705","https://openalex.org/W2884336796","https://openalex.org/W2884705835","https://openalex.org/W2884748363","https://openalex.org/W2884841859","https://openalex.org/W2885315720","https://openalex.org/W2886054672","https://openalex.org/W2886208449","https://openalex.org/W2886627908","https://openalex.org/W2888104887","https://openalex.org/W2889257467","https://openalex.org/W2889381503","https://openalex.org/W2889826018","https://openalex.org/W2890300667","https://openalex.org/W2890501899","https://openalex.org/W2890990246","https://openalex.org/W2891577800","https://openalex.org/W2892193782","https://openalex.org/W2893776390","https://openalex.org/W2898130317","https://openalex.org/W2898222539","https://openalex.org/W2899247965","https://openalex.org/W2899536177","https://openalex.org/W2911566892","https://openalex.org/W2911568801","https://openalex.org/W2911687977","https://openalex.org/W2938377221","https://openalex.org/W2950896690","https://openalex.org/W4242318543"],"related_works":["https://openalex.org/W2799529293","https://openalex.org/W406616055","https://openalex.org/W4362472892","https://openalex.org/W3214394573","https://openalex.org/W3084162811","https://openalex.org/W2367514298","https://openalex.org/W2964191569","https://openalex.org/W2086452998","https://openalex.org/W2996713688","https://openalex.org/W2294187591"],"abstract_inverted_index":{",":[0],"especially":[1],"strains":[2],"with":[3],"certain":[4],"specific":[5],"mechanisms":[6],"of":[7,32],"resistance.":[8],"A":[9],"section":[10],"is":[11],"devoted":[12],"to":[13],"reviewing":[14],"upcoming":[15],"active":[16],"drugs":[17],"such":[18,29],"as":[19,30,42],"imipenem-relebactam,":[20],"cefepime-zidebactam,":[21],"cefiderocol,":[22],"and":[23,38],"murepavadin.":[24],"Finally,":[25],"other":[26],"therapeutic":[27],"strategies,":[28],"use":[31],"vaccines,":[33],"antibodies,":[34],"bacteriocins,":[35],"anti-quorum":[36],"sensing,":[37],"bacteriophages,":[39],"are":[40],"described":[41],"future":[43],"options.":[44]},"counts_by_year":[{"year":2026,"cited_by_count":110},{"year":2025,"cited_by_count":180},{"year":2024,"cited_by_count":155},{"year":2023,"cited_by_count":163},{"year":2022,"cited_by_count":169},{"year":2021,"cited_by_count":120},{"year":2020,"cited_by_count":59},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4}],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2025-10-10T00:00:00"}
