{"id":"https://openalex.org/W2970044619","doi":null,"title":"Biopsy Records Do Not Reduce Diagnosis Variability in Cancer Patient EHRs: Are We More Uncertain After Knowing?","display_name":"Biopsy Records Do Not Reduce Diagnosis Variability in Cancer Patient EHRs: Are We More Uncertain After Knowing?","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2970044619","mag":"2970044619","pmid":"https://pubmed.ncbi.nlm.nih.gov/29888044","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961789"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5961789","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Jt Summits Transl Sci Proc","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066675455","display_name":"Franck Diaz\u2010Garelli","orcid":"https://orcid.org/0000-0002-4346-3799","observed_orcids":["https://orcid.org/0000-0002-4346-3799"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose-Franck Diaz-Garelli","raw_affiliation_strings":["Wake Forest Baptist Medical Center, Winston Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest Baptist Medical Center, Winston Salem, NC","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012688014","display_name":"Brian J. Wells","orcid":"https://orcid.org/0000-0001-7310-6525","observed_orcids":["https://orcid.org/0000-0001-7310-6525"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian J Wells","raw_affiliation_strings":["Wake Forest Baptist Medical Center, Winston Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest Baptist Medical Center, Winston Salem, NC","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021315592","display_name":"Caleb Yelton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caleb Yelton","raw_affiliation_strings":["Wake Forest Baptist Medical Center, Winston Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest Baptist Medical Center, Winston Salem, NC","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023144181","display_name":"Roy Ervin Strowd III","orcid":"https://orcid.org/0000-0001-6651-5267","observed_orcids":["https://orcid.org/0000-0001-6651-5267"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roy Strowd","raw_affiliation_strings":["Wake Forest Baptist Medical Center, Winston Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest Baptist Medical Center, Winston Salem, NC","institution_ids":["https://openalex.org/I1282516798"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023480695","display_name":"\u00dcmit Topalo\u011dlu","orcid":"https://orcid.org/0000-0002-3241-8773","observed_orcids":["https://orcid.org/0000-0002-3241-8773"]},"institutions":[{"id":"https://openalex.org/I1282516798","display_name":"Atrium Health Wake Forest Baptist","ror":"https://ror.org/04v8djg66","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282516798","https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Umit Topaloglu","raw_affiliation_strings":["Wake Forest Baptist Medical Center, Winston Salem, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wake Forest Baptist Medical Center, Winston Salem, NC","institution_ids":["https://openalex.org/I1282516798"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1282516798"],"apc_list":null,"apc_paid":null,"fwci":1.7491,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.84581827,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"2017","issue":null,"first_page":"72","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14400","display_name":"Medical Coding and Health Information","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T14400","display_name":"Medical Coding and Health Information","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electronic-health-records","display_name":"electronic health records","score":0.7649999856948853},{"id":"https://openalex.org/keywords/diagnostic-coding","display_name":"diagnosis coding","score":0.41499999165534973},{"id":"https://openalex.org/keywords/surgical-pathology-reporting","display_name":"surgical pathology reporting","score":0.6800000071525574},{"id":"https://openalex.org/keywords/brain-tumors","display_name":"brain tumors","score":0.8759999871253967},{"id":"https://openalex.org/keywords/diagnostic-uncertainty","display_name":"diagnostic uncertainty","score":0.4790000021457672},{"id":"https://openalex.org/keywords/cancer-diagnosis","display_name":"cancer diagnosis","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.761759877204895},{"id":"https://openalex.org/C45827449","wikidata":"https://www.wikidata.org/wiki/Q5270338","display_name":"Diagnosis code","level":3,"score":0.6309900283813477},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.546492338180542},{"id":"https://openalex.org/C82157600","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic test","level":2,"score":0.5209763646125793},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.5027265548706055},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.4777776002883911},{"id":"https://openalex.org/C179518139","wikidata":"https://www.wikidata.org/wiki/Q5140297","display_name":"Coding (social sciences)","level":2,"score":0.47509777545928955},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.4515092968940735},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.42798706889152527},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.4097650349140167},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32019326090812683},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.24775147438049316},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.22753754258155823},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.2146742045879364},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.15829643607139587},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1576155126094818},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:5961789","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Jt Summits Transl Sci Proc","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:4944171","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5961789","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:29888044","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29888044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science","raw_type":"Journal Article"},{"id":"mag:2970044619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29888044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5961789","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5961789/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AMIA Jt Summits Transl Sci Proc","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1849232265","display_name":"Wake Forest Clinical and Translational Science Award","funder_award_id":"UL1TR001420","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4052805727","display_name":"Postdoctoral Research, Instruction, and Mentoring Experience (PRIME)","funder_award_id":"K12GM102773","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000328302","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA012197","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2970044619.pdf","grobid_xml":"https://content.openalex.org/works/W2970044619.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1492309945","https://openalex.org/W1587439776","https://openalex.org/W1779612606","https://openalex.org/W1808652302","https://openalex.org/W1906650920","https://openalex.org/W1968088779","https://openalex.org/W1969208427","https://openalex.org/W1985547591","https://openalex.org/W1985926725","https://openalex.org/W1995967301","https://openalex.org/W1997057722","https://openalex.org/W2006952048","https://openalex.org/W2011627323","https://openalex.org/W2018161914","https://openalex.org/W2020197112","https://openalex.org/W2063613784","https://openalex.org/W2065391044","https://openalex.org/W2076934169","https://openalex.org/W2083468430","https://openalex.org/W2087779040","https://openalex.org/W2103351853","https://openalex.org/W2104333617","https://openalex.org/W2104608657","https://openalex.org/W2112861930","https://openalex.org/W2114388055","https://openalex.org/W2121382432","https://openalex.org/W2131965060","https://openalex.org/W2137796099","https://openalex.org/W2138278593","https://openalex.org/W2142456735","https://openalex.org/W2158939484","https://openalex.org/W2239231358","https://openalex.org/W2319214361","https://openalex.org/W2324370542","https://openalex.org/W2395975379","https://openalex.org/W2401036267","https://openalex.org/W2410631492","https://openalex.org/W2495120132","https://openalex.org/W2518786827","https://openalex.org/W2758723248","https://openalex.org/W4239825304","https://openalex.org/W4285719527","https://openalex.org/W4366076361"],"related_works":["https://openalex.org/W3021602169","https://openalex.org/W2965666399","https://openalex.org/W2418299364","https://openalex.org/W4387394742","https://openalex.org/W1980570292","https://openalex.org/W4319657117","https://openalex.org/W2486450071","https://openalex.org/W2404333230","https://openalex.org/W1493047760","https://openalex.org/W1849931491"],"abstract_inverted_index":{"Diagnostic":[0],"codes":[1,59,122,142],"are":[2,17],"crucial":[3],"for":[4,47],"analyses":[5],"of":[6,34,44,57,77,90,140,148,162],"electronic":[7],"health":[8],"record":[9],"(EHR)":[10],"data":[11],"but":[12],"their":[13],"accuracy":[14],"and":[15,109,151],"precision":[16,113],"often":[18],"lacking.":[19],"Although":[20,120],"providers":[21],"enter":[22],"precise":[23],"diagnoses":[24],"into":[25],"progress":[26],"notes,":[27],"billing":[28],"standards":[29],"may":[30],"limit":[31],"the":[32,42,55,70,88,138,141,149,160],"particularity":[33,154],"a":[35,48,134,163],"diagnostic":[36,50,58,85,93,102,112,121,129,157],"code.":[37,51],"Variability":[38],"also":[39],"arises":[40],"from":[41],"creation":[43],"multiple":[45],"descriptions":[46,94],"particular":[49],"We":[52],"hypothesized":[53],"that":[54],"variability":[56,139,152],"would":[60],"be":[61,146],"greater":[62],"before":[63],"surgical":[64],"pathology":[65,86,130],"results":[66],"were":[67,95],"recorded":[68],"in":[69,101,111,137,153,155],"medical":[71],"record.":[72],"A":[73],"well":[74],"annotated":[75],"cohort":[76],"patients":[78],"with":[79],"brain":[80],"neoplasms":[81],"was":[82,104,115,133],"studied.":[83],"After":[84],"reporting,":[87,131],"odds":[89],"more":[91,124],"distinct":[92,125],"2.30":[96],"times":[97,106,117],"higher":[98,107,118],"(p=0.00358),":[99],"entropy":[100,110],"sequences":[103],"2.26":[105],"(p=0.0259)":[108],"scores":[114],"15.5":[116],"(p=0.0324).":[119],"became":[123],"on":[126],"average":[127],"after":[128],"there":[132],"paradoxical":[135],"increase":[136],"selected.":[143],"Researchers":[144],"must":[145],"aware":[147],"inconsistencies":[150],"structured":[156],"coding":[158],"despite":[159],"presence":[161],"definitive":[164],"diagnosis.":[165]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2019-09-05T00:00:00"}