{"id":"https://openalex.org/W2969964941","doi":"https://doi.org/10.1016/j.pnpbp.2019.109735","title":"Efficacy of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: A systematic review and meta-analysis","display_name":"Efficacy of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: A systematic review and meta-analysis","publication_year":2019,"publication_date":"2019-08-19","ids":{"openalex":"https://openalex.org/W2969964941","doi":"https://doi.org/10.1016/j.pnpbp.2019.109735","mag":"2969964941","pmid":"https://pubmed.ncbi.nlm.nih.gov/31437480"},"language":"en","primary_location":{"id":"doi:10.1016/j.pnpbp.2019.109735","doi":"https://doi.org/10.1016/j.pnpbp.2019.109735","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pnpbp.2019.109735","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022798675","display_name":"Anees Bahji","orcid":"https://orcid.org/0000-0002-3490-314X","observed_orcids":["https://orcid.org/0000-0002-3490-314X"]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Anees Bahji","raw_affiliation_strings":["Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada. Electronic address: 0ab104@queensu.ca","Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","Department of Public Health Sciences, Queen\u2019s University, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Department of Public Health Sciences, Queen's University, Kingston, Ontario, Canada. Electronic address: 0ab104@queensu.ca","institution_ids":["https://openalex.org/I204722609"]},{"raw_affiliation_string":"Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]},{"raw_affiliation_string":"Department of Public Health Sciences, Queen\u2019s University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055778919","display_name":"Ashleigh Forsyth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]},{"id":"https://openalex.org/I4405268446","display_name":"Providence Care Hospital","ror":"https://ror.org/00zq1aj91","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4405268446"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ashleigh Forsyth","raw_affiliation_strings":["Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Providence Care Hospital, Kingston, Ontario, Canada","Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","Providence Care Hospital, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Providence Care Hospital, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609","https://openalex.org/I4405268446"]},{"raw_affiliation_string":"Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]},{"raw_affiliation_string":"Providence Care Hospital, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I4405268446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060281456","display_name":"Dianne Groll","orcid":"https://orcid.org/0000-0001-6913-5710","observed_orcids":["https://orcid.org/0000-0001-6913-5710"]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Dianne Groll","raw_affiliation_strings":["Department of Psychiatry, Queen's University, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Queen's University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021568220","display_name":"Emily R. Hawken","orcid":"https://orcid.org/0000-0002-4980-9674","observed_orcids":["https://orcid.org/0000-0002-4980-9674"]},"institutions":[{"id":"https://openalex.org/I204722609","display_name":"Queen's University","ror":"https://ror.org/02y72wh86","country_code":"CA","type":"education","lineage":["https://openalex.org/I204722609"]},{"id":"https://openalex.org/I4405268446","display_name":"Providence Care Hospital","ror":"https://ror.org/00zq1aj91","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4405268446"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Emily R. Hawken","raw_affiliation_strings":["Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Providence Care Hospital, Kingston, Ontario, Canada","Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","Providence Care Hospital, Kingston, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Queen's University, Kingston, Ontario, Canada; Providence Care Hospital, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609","https://openalex.org/I4405268446"]},{"raw_affiliation_string":"Department of Psychiatry, Queen\u2019s University, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I204722609"]},{"raw_affiliation_string":"Providence Care Hospital, Kingston, Ontario, Canada","institution_ids":["https://openalex.org/I4405268446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5022798675"],"corresponding_institution_ids":["https://openalex.org/I204722609"],"apc_list":{"value":2400,"currency":"USD","value_usd":2400},"apc_paid":null,"fwci":1.3692,"has_fulltext":false,"cited_by_count":96,"citation_normalized_percentile":{"value":0.78716745,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"96","issue":null,"first_page":"109735","last_page":"109735"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12553","display_name":"Psychedelics and Drug Studies","score":0.7670999765396118,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12553","display_name":"Psychedelics and Drug Studies","score":0.7670999765396118,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.2222999930381775,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11921","display_name":"Electroconvulsive Therapy Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mdma-assisted-therapy","display_name":"MDMA-assisted psychotherapy","score":0.996999979019165},{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.8569999933242798},{"id":"https://openalex.org/keywords/mdma","display_name":"MDMA","score":0.8289999961853027},{"id":"https://openalex.org/keywords/ptsd-symptom-reduction","display_name":"PTSD symptom reduction","score":0.8119999766349792},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.8410000205039978},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.625},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.7879999876022339},{"id":"https://openalex.org/keywords/psychedelic-therapy","display_name":"psychedelic therapy","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C2780876324","wikidata":"https://www.wikidata.org/wiki/Q69488","display_name":"MDMA","level":2,"score":0.8157467842102051},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6916214227676392},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5822184681892395},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5557498335838318},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4547937512397766},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4427061378955841},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4415636658668518},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4138687551021576},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.40156060457229614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1721983551979065},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.10402563214302063},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011613","descriptor_name":"Psychotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D013313","descriptor_name":"Stress Disorders, Post-Traumatic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D015928","descriptor_name":"Cognitive Behavioral Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018759","descriptor_name":"Adrenergic Uptake Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D018817","descriptor_name":"N-Methyl-3,4-methylenedioxyamphetamine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.pnpbp.2019.109735","doi":"https://doi.org/10.1016/j.pnpbp.2019.109735","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pnpbp.2019.109735","pdf_url":null,"source":{"id":"https://openalex.org/S142279999","display_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","issn_l":"0278-5846","issn":["0278-5846","1878-4216"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","raw_type":"journal-article"},{"id":"pmid:31437480","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31437480","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Progress in neuro-psychopharmacology & biological psychiatry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W138586294","https://openalex.org/W155331202","https://openalex.org/W1514491136","https://openalex.org/W1514792206","https://openalex.org/W1540425568","https://openalex.org/W1788048136","https://openalex.org/W1796823137","https://openalex.org/W1964851255","https://openalex.org/W1964972447","https://openalex.org/W1969892668","https://openalex.org/W1972551146","https://openalex.org/W1994673996","https://openalex.org/W1995263930","https://openalex.org/W2003532970","https://openalex.org/W2003585110","https://openalex.org/W2005621296","https://openalex.org/W2007549333","https://openalex.org/W2007985340","https://openalex.org/W2013923425","https://openalex.org/W2016255142","https://openalex.org/W2019004312","https://openalex.org/W2028756415","https://openalex.org/W2028998494","https://openalex.org/W2029410796","https://openalex.org/W2033174093","https://openalex.org/W2044428513","https://openalex.org/W2045543698","https://openalex.org/W2045664047","https://openalex.org/W2057069777","https://openalex.org/W2067658969","https://openalex.org/W2073927880","https://openalex.org/W2076507685","https://openalex.org/W2089004346","https://openalex.org/W2089149909","https://openalex.org/W2089306255","https://openalex.org/W2093943230","https://openalex.org/W2093982682","https://openalex.org/W2096933190","https://openalex.org/W2098234705","https://openalex.org/W2098923148","https://openalex.org/W2102027817","https://openalex.org/W2109121812","https://openalex.org/W2116280488","https://openalex.org/W2121748618","https://openalex.org/W2127654449","https://openalex.org/W2134015193","https://openalex.org/W2137981069","https://openalex.org/W2140634520","https://openalex.org/W2142184494","https://openalex.org/W2147606470","https://openalex.org/W2147821006","https://openalex.org/W2159597393","https://openalex.org/W2159630298","https://openalex.org/W2163014120","https://openalex.org/W2168194391","https://openalex.org/W2170792539","https://openalex.org/W2171035570","https://openalex.org/W2193378755","https://openalex.org/W2218174899","https://openalex.org/W2257615813","https://openalex.org/W2283505034","https://openalex.org/W2283929383","https://openalex.org/W2292804940","https://openalex.org/W2334295439","https://openalex.org/W2343567633","https://openalex.org/W2440481462","https://openalex.org/W2460356786","https://openalex.org/W2465993615","https://openalex.org/W2494226394","https://openalex.org/W2507165056","https://openalex.org/W2517765349","https://openalex.org/W2524355626","https://openalex.org/W2553282953","https://openalex.org/W2592339042","https://openalex.org/W2611299108","https://openalex.org/W2611362676","https://openalex.org/W2739337936","https://openalex.org/W2751968906","https://openalex.org/W2764244927","https://openalex.org/W2783806245","https://openalex.org/W2784340661","https://openalex.org/W2792164490","https://openalex.org/W2794934757","https://openalex.org/W2799742551","https://openalex.org/W2899027265","https://openalex.org/W2905272468","https://openalex.org/W2915031944","https://openalex.org/W2931582381","https://openalex.org/W2944263526","https://openalex.org/W3005563669","https://openalex.org/W3022903699","https://openalex.org/W4238626981","https://openalex.org/W6750345151","https://openalex.org/W6750648856"],"related_works":["https://openalex.org/W7110582841","https://openalex.org/W6889881343","https://openalex.org/W4403255583","https://openalex.org/W4415357511","https://openalex.org/W2910921484","https://openalex.org/W4294189615","https://openalex.org/W4399701295","https://openalex.org/W2109121812","https://openalex.org/W7143392773","https://openalex.org/W6926884405"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":9}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-08-29T00:00:00"}