{"id":"https://openalex.org/W2969647239","doi":null,"title":"\uc554 \uce58\ub8cc \ud45c\uc801\uc73c\ub85c\uc368 cathepsin S","display_name":"\uc554 \uce58\ub8cc \ud45c\uc801\uc73c\ub85c\uc368 cathepsin S","publication_year":2018,"publication_date":"2018-06-01","ids":{"openalex":"https://openalex.org/W2969647239","mag":"2969647239"},"language":"ko","primary_location":{"id":"mag:2969647239","doi":null,"is_oa":false,"landing_page_url":"http://dspace.kci.go.kr/handle/kci/1064231","pdf_url":null,"source":{"id":"https://openalex.org/S2947666954","display_name":"JoLS Journal of Life Sciences","issn_l":"2688-1020","issn":["2688-1020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4323237768","host_organization_name":"Society of Life Sciences","host_organization_lineage":["https://openalex.org/P4323237768"],"host_organization_lineage_names":["Society of Life Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"JoLS Journal of Life Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028360957","display_name":"\uc6b0\uc120\ubbfc","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\uc6b0\uc120\ubbfc","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023771868","display_name":"Taeg Kyu Kwon","orcid":"https://orcid.org/0000-0003-1204-2059","observed_orcids":["https://orcid.org/0000-0003-1204-2059","https://orcid.org/0000-0002-9794-6112"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Taeg Kyu Kwon","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1204-2059","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"6","first_page":"753","last_page":"763"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cathepsin-s","display_name":"cathepsin S","score":1.0},{"id":"https://openalex.org/keywords/cysteine-cathepsins","display_name":"cysteine cathepsins","score":0.9729999899864197},{"id":"https://openalex.org/keywords/cancer-therapy-targets","display_name":"cancer therapy targets","score":0.7480000257492065},{"id":"https://openalex.org/keywords/endolysosomal-pathway","display_name":"endolysosomal pathway","score":0.6510000228881836},{"id":"https://openalex.org/keywords/tumor-angiogenesis","display_name":"tumor angiogenesis","score":0.5979999899864197},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7850000262260437},{"id":"https://openalex.org/keywords/mhc-class-ii-antigen-presentation","display_name":"MHC class II antigen presentation","score":0.843999981880188},{"id":"https://openalex.org/keywords/cd74","display_name":"CD74","score":0.6370000243186951},{"id":"https://openalex.org/keywords/cell-death","display_name":"cell death","score":0.5860000252723694},{"id":"https://openalex.org/keywords/gene-amplification","display_name":"gene amplification","score":0.5059999823570251},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9750000238418579}],"concepts":[{"id":"https://openalex.org/C34695024","wikidata":"https://www.wikidata.org/wiki/Q14902030","display_name":"Cathepsin O","level":4,"score":0.9171428680419922},{"id":"https://openalex.org/C78553746","wikidata":"https://www.wikidata.org/wiki/Q423561","display_name":"Cathepsin A","level":4,"score":0.8825415372848511},{"id":"https://openalex.org/C174937957","wikidata":"https://www.wikidata.org/wiki/Q18248582","display_name":"Cathepsin E","level":5,"score":0.8082269430160522},{"id":"https://openalex.org/C51618164","wikidata":"https://www.wikidata.org/wiki/Q5052484","display_name":"Cathepsin H","level":4,"score":0.8057116270065308},{"id":"https://openalex.org/C81216549","wikidata":"https://www.wikidata.org/wiki/Q18022191","display_name":"Cathepsin L1","level":4,"score":0.7407156229019165},{"id":"https://openalex.org/C145734084","wikidata":"https://www.wikidata.org/wiki/Q14902080","display_name":"Cathepsin C","level":4,"score":0.6596719622612},{"id":"https://openalex.org/C151701858","wikidata":"https://www.wikidata.org/wiki/Q14902024","display_name":"Cathepsin S","level":4,"score":0.6261774897575378},{"id":"https://openalex.org/C28021979","wikidata":"https://www.wikidata.org/wiki/Q14911946","display_name":"Cathepsin B","level":3,"score":0.5671595335006714},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5102639198303223},{"id":"https://openalex.org/C2780034444","wikidata":"https://www.wikidata.org/wiki/Q5052485","display_name":"Cathepsin L","level":4,"score":0.4911896884441376},{"id":"https://openalex.org/C167844969","wikidata":"https://www.wikidata.org/wiki/Q426245","display_name":"Cathepsin","level":3,"score":0.4813971519470215},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4663388431072235},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.35627979040145874},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2617884576320648},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24602791666984558}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2969647239","doi":null,"is_oa":false,"landing_page_url":"http://dspace.kci.go.kr/handle/kci/1064231","pdf_url":null,"source":{"id":"https://openalex.org/S2947666954","display_name":"JoLS Journal of Life Sciences","issn_l":"2688-1020","issn":["2688-1020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4323237768","host_organization_name":"Society of Life Sciences","host_organization_lineage":["https://openalex.org/P4323237768"],"host_organization_lineage_names":["Society of Life Sciences"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"JoLS Journal of Life Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":108,"referenced_works":["https://openalex.org/W29354254","https://openalex.org/W77022750","https://openalex.org/W154972788","https://openalex.org/W183778759","https://openalex.org/W1481507356","https://openalex.org/W1519534578","https://openalex.org/W1550214637","https://openalex.org/W1553533097","https://openalex.org/W1582842606","https://openalex.org/W1598023718","https://openalex.org/W1604739148","https://openalex.org/W1812339273","https://openalex.org/W1892030779","https://openalex.org/W1964064744","https://openalex.org/W1964415617","https://openalex.org/W1967860838","https://openalex.org/W1969707082","https://openalex.org/W1973181401","https://openalex.org/W1980122273","https://openalex.org/W1982360880","https://openalex.org/W1983122657","https://openalex.org/W1993643473","https://openalex.org/W1993849398","https://openalex.org/W1993992129","https://openalex.org/W1994641823","https://openalex.org/W2000176833","https://openalex.org/W2001621817","https://openalex.org/W2002174978","https://openalex.org/W2003043590","https://openalex.org/W2007771379","https://openalex.org/W2009311291","https://openalex.org/W2010912389","https://openalex.org/W2013284852","https://openalex.org/W2019384302","https://openalex.org/W2033558282","https://openalex.org/W2034680726","https://openalex.org/W2034683251","https://openalex.org/W2035329189","https://openalex.org/W2044601575","https://openalex.org/W2046062086","https://openalex.org/W2046848104","https://openalex.org/W2050499474","https://openalex.org/W2054462619","https://openalex.org/W2055793916","https://openalex.org/W2055930652","https://openalex.org/W2056378929","https://openalex.org/W2059977705","https://openalex.org/W2061864588","https://openalex.org/W2062249523","https://openalex.org/W2070163884","https://openalex.org/W2074364707","https://openalex.org/W2075503331","https://openalex.org/W2075729810","https://openalex.org/W2076255850","https://openalex.org/W2078520504","https://openalex.org/W2078566293","https://openalex.org/W2081105252","https://openalex.org/W2084882698","https://openalex.org/W2086295016","https://openalex.org/W2087693731","https://openalex.org/W2093783077","https://openalex.org/W2097619603","https://openalex.org/W2097865892","https://openalex.org/W2102257705","https://openalex.org/W2103324057","https://openalex.org/W2104047638","https://openalex.org/W2104540904","https://openalex.org/W2109747041","https://openalex.org/W2116238049","https://openalex.org/W2117735446","https://openalex.org/W2118025220","https://openalex.org/W2129636440","https://openalex.org/W2130440034","https://openalex.org/W2134933135","https://openalex.org/W2137122152","https://openalex.org/W2140196515","https://openalex.org/W2143598351","https://openalex.org/W2145265436","https://openalex.org/W2148051205","https://openalex.org/W2152462290","https://openalex.org/W2153215523","https://openalex.org/W2153512675","https://openalex.org/W2159087408","https://openalex.org/W2161579181","https://openalex.org/W2161654709","https://openalex.org/W2163207898","https://openalex.org/W2165354092","https://openalex.org/W2169577908","https://openalex.org/W2169872465","https://openalex.org/W2171744625","https://openalex.org/W2181240439","https://openalex.org/W2187863746","https://openalex.org/W2206381430","https://openalex.org/W2277346997","https://openalex.org/W2292449879","https://openalex.org/W2400119641","https://openalex.org/W2409885875","https://openalex.org/W2417602147","https://openalex.org/W2419744185","https://openalex.org/W2465704855","https://openalex.org/W2507900780","https://openalex.org/W2520068325","https://openalex.org/W2560254877","https://openalex.org/W2756271200","https://openalex.org/W2792412577","https://openalex.org/W2795691578","https://openalex.org/W2883613047","https://openalex.org/W3020945095"],"related_works":["https://openalex.org/W2333201325","https://openalex.org/W2042594779","https://openalex.org/W1834367856","https://openalex.org/W4409388749","https://openalex.org/W4403830650","https://openalex.org/W7035923749","https://openalex.org/W2176714462","https://openalex.org/W7139679587","https://openalex.org/W4414560857","https://openalex.org/W3014156497"],"abstract_inverted_index":{"Cathepsin\uc740":[0],"\ub9ac\uc18c\uc880\uc5d0":[1],"\uc874\uc7ac\ud558\ub294":[2],"\ud6a8\uc18c\ub85c,":[3],"\uc5d4\ub3c4\uc880-\ub9ac\uc18c\uc880":[4],"\uacbd\ub85c\ub97c":[5],"\ud1b5\ud558\uc5ec":[6],"\uc190\uc0c1\ub41c":[7],"\ub2e8\ubc31\uc9c8\uc758":[8],"\ubd84\ud574\ub97c":[9],"\uc720\ub3c4\ud55c\ub2e4.":[10,128],"\uc774\ub7ec\ud55c":[11],"cathepsin\uc740":[12,28],"\ud65c\uc131\ud654\ub418\ub294":[13],"\ucd09\ub9e4":[14],"\uc794\uae30":[15],"\uc704\uce58(catalytic":[16],"residue":[17],"site)\uc5d0":[18],"\ub530\ub77c":[19],"cysteine,":[20],"aspartate,":[21],"serine":[22],"cathepsin\uc73c\ub85c":[23],"\ub098\ub25c\ub2e4.":[24],"\ub2e4\uc591\ud55c":[25],"\uc554\uc138\ud3ec\uc5d0\uc11c":[26,113],"cysteine":[27,45],"\uc720\uc804\uc790":[29],"\uc99d\ud3ed\uc774\ub098":[30],"\uc804\uc0ac,":[31],"\ubc88\uc5ed,":[32],"\uc804\uc0ac":[33],"\ud6c4":[34],"\ub2e8\uacc4\ub97c":[35],"\ud1b5\ud574":[36,81],"\ub192\uc740":[37],"\ubc1c\ud604\uc744":[38],"\uc720\uc9c0\ud55c\ub2e4.":[39],"\ud2b9\ud788":[40,112],"cathepsin":[41,68,86,114,130],"S\uc758":[42,97,115],"\uacbd\uc6b0,":[43],"\ub2e4\ub978":[44],"cathepsin\uacfc":[46],"\ub2ec\ub9ac":[47],"\uc911\uc131":[48],"pH":[49],"\ud658\uacbd\uc5d0\uc11c\ub3c4":[50],"\uc548\uc815\uc801\uc73c\ub85c":[51],"\ud65c\uc131\ub3c4\ub97c":[52],"\uc720\uc9c0\ud558\uba70":[53],"\ud2b9\uc815":[54],"\uc870\uc9c1\uc5d0\uc11c":[55],"\ubc1c\ud604\uc774":[56],"\uc81c\ud55c\uc801\uc774\ub77c\ub294":[57],"\ud2b9\uc9d5\uc744":[58],"\uac00\uc9c0\uace0":[59],"\uc788\uae30":[60],"\ub54c\ubb38\uc5d0":[61],"\uc9c8\ubcd1\uc758":[62],"\ubbf8\uc138\ud658\uacbd\uc5d0\uc11c":[63],"\uc911\uc694\ud55c":[64,76],"\uc5ed\ud560\uc744":[65,94],"\ud55c\ub2e4.":[66,95],"\uba74\uc5ed\uc138\ud3ec\uc5d0\uc11c\uc758":[67],"S\ub294":[69,87,131],"\ubd88\ubcc0":[70],"\uc0ac\uc2ac(invariant":[71],"chain)\uc744":[72],"\ubd84\ud574\ud558\uc5ec":[73],"\ud56d\uc6d0":[74],"\uc81c\uc2dc\uc5d0":[75],"MHC":[77],"class":[78],"II\uc758":[79],"\ud65c\uc131\ud654\ub97c":[80],"\uba74\uc5ed":[82],"\ubc18\uc751\uc744":[83],"\uc870\uc808\ud558\uba70,":[84],"\uc554\uc138\ud3ec\uc5d0\uc11c\uc758":[85],"\uc804\uc774\uc640":[88],"\ud608\uad00\uc2e0\uc0dd\uc744":[89,119],"\uc870\uc808\ud568\uc73c\ub85c\uc368":[90],"\uc554\uc138\ud3ec\uc758":[91,123],"\uc131\uc7a5\uc744":[92],"\uc99d\uac00\uc2dc\ud0a4\ub294":[93],"Cathepsin":[96],"\ubc1c\ud604":[98,116],"\uc870\uc808\uc5d0":[99],"\ubb38\uc81c\uac00":[100],"\uc0dd\uae30\uba74":[101],"\uc554,":[102],"\uad00\uc808\uc5fc,":[103],"\uc2ec\ud608\uad00":[104],"\uc9c8\ud658\uc744":[105],"\ud3ec\ud568\ud55c":[106],"\ub9ce\uc740":[107],"\ubcd1\ub9ac\ud559\uc801":[108],"\ud604\uc0c1\uc5d0":[109],"\uc601\ud5a5\uc744":[110],"\ubbf8\uce5c\ub2e4.":[111],"\uc5b5\uc81c\uc640":[117],"\uacb0\ud568\uc740":[118],"\uc5b5\uc81c\uc2dc\ud0ac":[120],"\ubfd0\ub9cc":[121],"\uc544\ub2c8\ub77c,":[122],"\uc131\uc7a5\uacfc":[124],"\uc804\uc774\ub97c":[125],"\uac10\uc18c\uc2dc\ud0a4\uace0":[126],"\uc138\ud3ec\uc0ac\uba78\uc744":[127],"\ub530\ub77c\uc11c,":[129],"\uc554":[132],"\uce58\ub8cc\uc5d0":[133],"\uc788\uc5b4":[134],"\uc88b\uc740":[135],"\ud45c\uc801\uc774":[136],"\ub420":[137],"\uc218":[138],"\uc788\ub2e4.":[139]},"counts_by_year":[],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2019-08-29T00:00:00"}
