{"id":"https://openalex.org/W2969433956","doi":"https://doi.org/10.15252/embr.201947903","title":"Inter\u2010organ communication: a gatekeeper for metabolic health","display_name":"Inter\u2010organ communication: a gatekeeper for metabolic health","publication_year":2019,"publication_date":"2019-08-19","ids":{"openalex":"https://openalex.org/W2969433956","doi":"https://doi.org/10.15252/embr.201947903","mag":"2969433956","pmid":"https://pubmed.ncbi.nlm.nih.gov/31423716","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6726901"},"language":"en","primary_location":{"id":"doi:10.15252/embr.201947903","doi":"https://doi.org/10.15252/embr.201947903","is_oa":false,"landing_page_url":"https://doi.org/10.15252/embr.201947903","pdf_url":null,"source":{"id":"https://openalex.org/S57252141","display_name":"EMBO Reports","issn_l":"1469-221X","issn":["1469-221X","1469-3178"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Reports","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6726901","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047211503","display_name":"Judit Castillo\u2010Armengol","orcid":"https://orcid.org/0000-0001-7833-0569","observed_orcids":["https://orcid.org/0000-0001-7833-0569"]},"institutions":[{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Judit Castillo\u2010Armengol","raw_affiliation_strings":["Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I97565354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009899895","display_name":"Llu\u00eds Fajas","orcid":"https://orcid.org/0000-0002-1283-9503","observed_orcids":["https://orcid.org/0000-0002-1283-9503"]},"institutions":[{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Lluis Fajas","raw_affiliation_strings":["Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-1283-9503","affiliations":[{"raw_affiliation_string":"Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I97565354"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015907930","display_name":"Isabel C. L\u00f3pez\u2010Mej\u00eda","orcid":"https://orcid.org/0000-0001-5918-0227","observed_orcids":["https://orcid.org/0000-0001-5918-0227"]},"institutions":[{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Isabel C Lopez\u2010Mejia","raw_affiliation_strings":["Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I97565354"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009899895","https://openalex.org/A5015907930"],"corresponding_institution_ids":["https://openalex.org/I97565354"],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":1.7905,"has_fulltext":false,"cited_by_count":182,"citation_normalized_percentile":{"value":0.88167939,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"20","issue":"9","first_page":"e47903","last_page":"e47903"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inter-organ-communication","display_name":"inter-organ communication","score":0.9900000095367432},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.8299999833106995},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/metabolic-crosstalk","display_name":"metabolic crosstalk","score":0.753000020980835},{"id":"https://openalex.org/keywords/hormones","display_name":"hormones","score":0.6700000166893005},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.996999979019165},{"id":"https://openalex.org/keywords/bioactive-peptides","display_name":"bioactive peptides","score":0.9670000076293945},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8769999742507935},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.8679999709129333},{"id":"https://openalex.org/keywords/treatment-strategy","display_name":"treatment options","score":0.6290000081062317}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3857768177986145},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3521038889884949}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.15252/embr.201947903","doi":"https://doi.org/10.15252/embr.201947903","is_oa":false,"landing_page_url":"https://doi.org/10.15252/embr.201947903","pdf_url":null,"source":{"id":"https://openalex.org/S57252141","display_name":"EMBO Reports","issn_l":"1469-221X","issn":["1469-221X","1469-3178"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6726901","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6726901","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO Rep","raw_type":"Text"},{"id":"pmid:31423716","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31423716","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO reports","raw_type":"Journal Article"},{"id":"pmh:oai:serval.unil.ch:BIB_3D85056E88C8","doi":null,"is_oa":true,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_3D85056E88C8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO reports, vol. 20, no. 9, pp. e47903","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:oai:iris.unil.ch:iris/98272","doi":null,"is_oa":true,"landing_page_url":"https://iris.unil.ch/handle/iris/98272","pdf_url":null,"source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"review article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:6726901","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6726901","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO Rep","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8999999761581421,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5587090569","display_name":"Role of the SR protein SRSF1 in the integration of gene expression in adipose tissue during metabolic syndrome","funder_award_id":"168077","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":176,"referenced_works":["https://openalex.org/W240175869","https://openalex.org/W565001682","https://openalex.org/W1513674275","https://openalex.org/W1637971961","https://openalex.org/W1804718109","https://openalex.org/W1896220440","https://openalex.org/W1947875006","https://openalex.org/W1964063591","https://openalex.org/W1964532167","https://openalex.org/W1964603672","https://openalex.org/W1972553581","https://openalex.org/W1975544443","https://openalex.org/W1975673963","https://openalex.org/W1976348644","https://openalex.org/W1979030077","https://openalex.org/W1985982057","https://openalex.org/W1986410493","https://openalex.org/W1986602268","https://openalex.org/W1988527243","https://openalex.org/W1990112639","https://openalex.org/W1990777401","https://openalex.org/W1991845771","https://openalex.org/W1993235686","https://openalex.org/W1994270208","https://openalex.org/W1996713062","https://openalex.org/W1999310337","https://openalex.org/W1999624003","https://openalex.org/W2000665430","https://openalex.org/W2002941555","https://openalex.org/W2008675205","https://openalex.org/W2009127988","https://openalex.org/W2010408206","https://openalex.org/W2011588666","https://openalex.org/W2013082477","https://openalex.org/W2014093079","https://openalex.org/W2020515276","https://openalex.org/W2022349101","https://openalex.org/W2026363549","https://openalex.org/W2026372454","https://openalex.org/W2027241056","https://openalex.org/W2032919119","https://openalex.org/W2037226098","https://openalex.org/W2041451676","https://openalex.org/W2042444876","https://openalex.org/W2043531340","https://openalex.org/W2043958887","https://openalex.org/W2044386584","https://openalex.org/W2045522606","https://openalex.org/W2045656711","https://openalex.org/W2047306805","https://openalex.org/W2047589919","https://openalex.org/W2049375442","https://openalex.org/W2050509217","https://openalex.org/W2053079324","https://openalex.org/W2057919982","https://openalex.org/W2061096962","https://openalex.org/W2061863697","https://openalex.org/W2062842771","https://openalex.org/W2067096633","https://openalex.org/W2068195538","https://openalex.org/W2074479414","https://openalex.org/W2074644777","https://openalex.org/W2075248627","https://openalex.org/W2078409165","https://openalex.org/W2081028309","https://openalex.org/W2081393100","https://openalex.org/W2082974347","https://openalex.org/W2084001707","https://openalex.org/W2085397620","https://openalex.org/W2086562954","https://openalex.org/W2087133453","https://openalex.org/W2088603277","https://openalex.org/W2090672107","https://openalex.org/W2091685843","https://openalex.org/W2092136583","https://openalex.org/W2097615700","https://openalex.org/W2100538674","https://openalex.org/W2104321619","https://openalex.org/W2108365604","https://openalex.org/W2111653877","https://openalex.org/W2112202133","https://openalex.org/W2114280375","https://openalex.org/W2116843182","https://openalex.org/W2117457995","https://openalex.org/W2119331212","https://openalex.org/W2121921343","https://openalex.org/W2123371309","https://openalex.org/W2124205424","https://openalex.org/W2126188293","https://openalex.org/W2128485668","https://openalex.org/W2131622156","https://openalex.org/W2132358997","https://openalex.org/W2134944069","https://openalex.org/W2135068779","https://openalex.org/W2137438007","https://openalex.org/W2143711558","https://openalex.org/W2144925128","https://openalex.org/W2145142659","https://openalex.org/W2153349010","https://openalex.org/W2155317536","https://openalex.org/W2155560632","https://openalex.org/W2158673389","https://openalex.org/W2163644328","https://openalex.org/W2163865122","https://openalex.org/W2165958384","https://openalex.org/W2165995731","https://openalex.org/W2168695748","https://openalex.org/W2170874580","https://openalex.org/W2181471414","https://openalex.org/W2319001492","https://openalex.org/W2339416165","https://openalex.org/W2361659253","https://openalex.org/W2440558121","https://openalex.org/W2465919060","https://openalex.org/W2470343227","https://openalex.org/W2471590266","https://openalex.org/W2474050011","https://openalex.org/W2506442946","https://openalex.org/W2515318044","https://openalex.org/W2518904228","https://openalex.org/W2520032353","https://openalex.org/W2556766149","https://openalex.org/W2567812618","https://openalex.org/W2571988049","https://openalex.org/W2586842569","https://openalex.org/W2587815451","https://openalex.org/W2588757737","https://openalex.org/W2604914239","https://openalex.org/W2605110590","https://openalex.org/W2610238951","https://openalex.org/W2611486163","https://openalex.org/W2623238236","https://openalex.org/W2624389654","https://openalex.org/W2625485505","https://openalex.org/W2737206084","https://openalex.org/W2739586877","https://openalex.org/W2739667313","https://openalex.org/W2753963188","https://openalex.org/W2756478885","https://openalex.org/W2767126254","https://openalex.org/W2767694961","https://openalex.org/W2769191713","https://openalex.org/W2774279346","https://openalex.org/W2782974118","https://openalex.org/W2783262542","https://openalex.org/W2784121457","https://openalex.org/W2789458740","https://openalex.org/W2796003794","https://openalex.org/W2799463911","https://openalex.org/W2799467504","https://openalex.org/W2800349415","https://openalex.org/W2800808913","https://openalex.org/W2800926943","https://openalex.org/W2803398082","https://openalex.org/W2808196629","https://openalex.org/W2809999132","https://openalex.org/W2810887760","https://openalex.org/W2883879320","https://openalex.org/W2886566773","https://openalex.org/W2886808233","https://openalex.org/W2887420502","https://openalex.org/W2889974216","https://openalex.org/W2894120184","https://openalex.org/W2894391873","https://openalex.org/W2899627734","https://openalex.org/W2900996634","https://openalex.org/W2902138037","https://openalex.org/W2905067650","https://openalex.org/W2907048060","https://openalex.org/W2907926991","https://openalex.org/W2908997056","https://openalex.org/W2913676190","https://openalex.org/W2918397108","https://openalex.org/W4237666794","https://openalex.org/W4240089340","https://openalex.org/W4253137490"],"related_works":["https://openalex.org/W2993039085","https://openalex.org/W4378746785","https://openalex.org/W4389648838","https://openalex.org/W1970053607","https://openalex.org/W7134917801","https://openalex.org/W4415531993","https://openalex.org/W4390653845","https://openalex.org/W2404883061","https://openalex.org/W2293920961","https://openalex.org/W4410245985"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":25},{"year":2025,"cited_by_count":29},{"year":2024,"cited_by_count":38},{"year":2023,"cited_by_count":30},{"year":2022,"cited_by_count":28},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-08-29T00:00:00"}
